Helena Hachul

Helena Hachul
Universidade Federal de São Paulo | UNIFESP · Departamento de Psicobiologia e Ginecologia

PhD MD

About

91
Publications
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Publications

Publications (91)
Article
Introduction The complaint of nocturnal awakening with headache (NAH), was prevalent (8.4%) in the São Paulo population and was associated with sleep disturbances, as demonstrated in a study conducted in 2007 (EPISONO). Indeed, this relationship between sleep and headache is well documented in the literature. Objective: To assess the incidence and...
Article
Introduction Sleep is essential for women’s health and its deprivation leads to serious physiological consequences. In addition, insomnia is a common complaint in postmenopausal women. Thus, the present study aimed to evaluate the effect of Lavandula angustifolia essential oil inhalation on sleep and menopausal symptoms in postmenopausal women with...
Article
Introduction Hormonal changes may trigger sleep disturbances in women. Insomnia affects one in every three-to-four of them, most likely during pre to post menopause, and especially in association with hot flashes. Thus, the present study aimed to investigate the occurrence of hot flashes among women with and without insomnia and on different reprod...
Article
Introduction The effects of hormonal contraceptives on sleep has been matter of debate in current literature. While some articles observed a sleep promoting effect and reduced sleep disordered breathing, others have failed to detect any result or even detected a worse sleep pattern in women using hormonal contraception. As the literature has been g...
Poster
Full-text available
Objective: The aim of the present case report is to present the effect of mindfulness meditation training in a chronic insomnia patient, presenting vasomotor symptoms and REM parasomnias (somnambulism) that did not improve with traditional pharmacological treatment. Method: This study follows a post-menopausal woman with day and night hot flashes a...
Article
Introduction Many postmenopausal women suffer from insomnia and chronic musculoskeletal pain, which are considered hallmarks of menopausal symptomatology. Our aim was to investigate the temporal association between chronic musculoskeletal pain and sleep in postmenopausal women in a 10-day actigraphic study. Methods This is a microlongitudinal stud...
Article
Full-text available
Introduction Disruption in regular menstrual cycle could modulate inflammatory profile. This context indicates that anovulation status could be related to low-grade inflammation leading to health impairments. We hypothesized that anovulatory women had higher circulating levels of inflammatory markers compared with women in regular menstrual cycle o...
Article
Introduction Previous reports account for beneficial effects of female sexual hormones administration (both estrogens and progestogens) and hormone replacement therapy in postmenopausal women, both as hypnogenic agents and potential therapeutic alternatives for obstructive sleep apnea and insomnia. Data are scarce for premenopausal women and the ef...
Article
Introduction Obstructive sleep apnea (OSA) is a highly prevalent sleep disorder. Obesity is the most common risk factor for OSA. In women, the prevalence of sleep apnea increases substantially during and after the onset of menopause as obesity is more prevalent in this reproductive life stage. Our aim was to identify the anthropometric measure most...
Chapter
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Global life expectancy has increased substantially over the last century. For women, this means that they now live nearly one-third of their lives in the climacteric period with the undesirable effects of hypoestrogenism. The consequences of this decrease in estrogen may occur in the short or long term. Among the early manifestations, the most impo...
Article
Background: Sleep disturbances and pain are assumed to be reciprocally linked. Insomnia and pain are central symptoms of the postmenopausal period and are closely related. Insomnia affects quality of life, increases pain sensitivity, the risk of pain-related disability, and other health problems. Objective: To investigate whether insomnia influence...
Article
Context • During the postmenopausal stage, women go through many remarkable changes, including physical, emotional, and hormonal. They also experience some unwanted effects, such as vasomotor symptoms, anxiety, and insomnia. The use of Bach flower remedies has been described as a supporting therapy for those symptoms. Objectives • The investigation...
Article
Objectives: Sleep is essential for physical and mental well-being. However, poor sleep is a common complaint among caregivers. The aim of the present study was to determine sleep patterns of caregiver-mothers (CM group) of sons with Duchenne muscular dystrophy (DMD) and also to examine the differences between non-carriers and carriers of the gene...
Article
Obstructive sleep apnea (OSA) has been associated with increased risk of cardiovascular morbidity and mortality. Although inflammatory markers may mediate this association, it is unknown the influence of gender in this mechanism. Thus, we aimed to evaluate the interaction effects between OSA and gender on metabolic and inflammatory profile in a pop...
Article
Objectives To investigate the association between reproductive life stage, pain perception and musculoskeletal pain complaint in a representative sample of women from São Paulo, Brazil. Methods A population-based survey was carried out with 574 women who were classified as being in the premenopausal or postmenopausal stage. They answered questions...
Article
Objective: This case report aimed to evaluate 4 months of yoga practice on the quality of life (QOL) and estradiol levels of two postmenopausal women. Methods: Participants were clinically healthy postmenopausal women, with follicle-stimulating hormone levels greater than or equal to 30 mIU/mL and a body mass index lower than 30 kg/m. The partic...
Article
Purpose: To characterize the onset of natural menopause and to investigate the associated factors with the age of menarche and natural menopause in a population aged 29-59 yrs in Sao Paulo, Brazil. Methods: In total, 426 women underwent clinical evaluation and blood collection for biochemical analysis. Participants were classified as being in the p...
Article
Full-text available
Several studies have reported an increase in the prevalence of adult female acne. This subtype of acne presents particular characteristics, and can be triggered by several factors such as smoking, stress, the use of oily cosmetics and even by poor sleep. Sleep quality is related to well-being and the maintenance of body homeostasis. In addition, se...
Article
Full-text available
Sleep disorders are commonly observed among postmenopausal women, with negative effects on their quality of life. The search for complementary therapies for sleep disorders during postmenopausal period is of high importance, and acupuncture stands out as an appropriate possibility. The present review intended to systematically evaluate the availabl...
Article
The current study aimed to investigate stages of reproductive aging as an associated factor for obstructive sleep apnea syndrome (OSAS) among women in a representative sample of Sao Paulo, Brazil. Four hundred seven women underwent clinical evaluation, polysomnography, and biochemical analysis. Stages of reproductive aging were defined as premenopa...
Article
Our objective was to investigate the influence of menopausal status on sleep patterns in a representative sample of women from São Paulo, Brazil. A population-based survey with a probabilistic three-stage cluster sample of the city of São Paulo was used to represent the local population according to gender, age (20-80 years) and socioeconomic statu...
Article
Sleep disorders are highly prevalent in patients with fibromyalgia (FM). Many of the daytime symptoms, such as chronic pain and fatigue, may be related to the non-restorative sleep patterns associated with the disease. Pain influences the sleep process and sleep disturbances decrease the pain threshold in a reciprocal framework. Thus, understanding...
Article
Full-text available
IntroductionThe task of the caregiver, especially a caregiving mother of a son with a chronic and fatal disease, may interfere with their quality of sleep, sexuality, and some hormone levels.AimThe aim of this study was to evaluate the sexual function and the quality of sleep of caregiving mothers of sons with Duchenne muscular dystrophy (DMD).Meth...
Article
Full-text available
With increases life expectancy, the incidence of undesirable manifestations of menopause has increased as well. The effects of lost ovarian function include progressive decrease in estradiol secretion, trophic changes in the breast, vasomotor symptoms, anxiety, depression, and sleep disorders. Insomnia, which has physiological consequences and can...
Article
ABSTRACT Menopause is an important episode in the life of women and for the great majority of women occurs in their fifties. The climacteric period, which is often associated with insomnia, represents one of the most important changes in the female reproductive cycle because it marks the end of reproductive capacity. Hormonal therapy has been consi...
Article
Introduction Insomnia is a frequent postmenopausal symptom and may be due to hormonal changes, depressive states related to this period of life, hot flashes or nocturia. Chiropractic care has been demonstrated to be effective in the treatment of these symptoms. Objectives The aim of this study was to review chiropractic interventions in postmenopa...
Article
To evaluate the frequency of sleep disorders, such as obstructive sleep apnea, restless leg syndrome and insomnia in overweight/obese postmenopausal women seen in a climacteric sleep disorders clinic. Thirty-four postmenopausal women were selected using the following inclusion criteria: age between 50 and 70 years; at least 12 months of amenorrhea;...
Article
Full-text available
OBJETIVOS: Avaliar a frequência dos distúrbios do sono, como apneia obstrutiva do sono, síndrome das pernas inquietas e insônia, em pacientes na pós-menopausa com sobrepeso/obesidade no ambulatório de distúrbios do sono no climatério. MÉTODOS: Foram selecionadas 34 pacientes na pós-menopausa, e os seguintes critérios de inclusão foram adotados: id...
Article
Purpose: Obstructive sleep apnea syndrome (OSAS) is associated with impaired cognition, especially executive functions. However, various of its comorbid conditions are also known to cause cognitive impairment, so it is unclear whether OSAS itself is responsible for cognitive deficits. Our aim was to determine the effects of OSAS on executive funct...
Article
Full-text available
Objective: Some studies have shown a higher prevalence of nonalcoholic fatty liver disease (NAFLD) and obstructive sleep apnea (OSA) in patients with polycystic ovary syndrome (PCOS). The objective of this study was to assess NAFLD in PCOS women with and without OSA. A possible role of high serum androgen levels in the development of OSA in PCOS w...
Article
Victims of child sexual abuse (CSA) often experience symptoms such as recurrent nightmares, which affect their adult life. This study aimed to evaluate the effect of psychotherapy on the quality of life and sleep in a female patient with a previous history of CSA. The patient was climacteric (menopausal transition) and treated in an outpatient clin...
Article
Mindfulness has been defined as being intentionally aware of internal and external experiences that occur at the present moment, without judgment. Techniques that develop mindfulness, such as meditation, have positive effects on reducing insomnia, a sleep disorder that is common both during and after menopause. Our aim was to establish whether post...
Article
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APS. 2013 abr/jun; 16(2): 122-128. 122 RESUMO Objetivo: Identificar o conhecimento sobre a Higiene do Sono em mulheres que frequentavam um ambulatório de climatério. Método: Os dados foram obtidos pelo preen-chimento de questionário sobre a higiene do sono, por 72 mulheres na perimenopausa/pós-menopausa, sendo que 30 eram atendidas pelo ambulatório...
Article
Objective: To investigate the effects of the phases of the menstrual cycle and the use of hormonal contraception on sleep patterns in a population-based study. Methods: In a prospective study carried out among premenopausal women between July and December 2007, a 3-stage cluster sampling was used to ensure accurate representation of the general...
Article
Objective: The aim of the present study was to assess whether menopausal status influences the occurrence of nocturnal awakening with headache (NAH) in the female population of Sao Paulo, Brazil. We also examined the relationship of this complaint to sociodemographic determinants, hot flushes, sleep quality and parameters, anxiety and depressive s...
Article
Background: Insomnia increases in frequency as women approach and pass through menopause. Studies have not shown acupuncture efficacy for insomnia in postmenopausal women. Objectives: The aim of this study was to evaluate the effectiveness of acupuncture therapy on sleep parameters, depression symptoms and quality of life in postmenopausal women...
Article
Full-text available
A menopausa ocorre na grande maioria das mulheres por volta dos 50 anos. Cerca de 70% das mulheres apresentam sintomas decorrentes da perda hormonal (hipoestrogenismo). Entre estes sintomas estão: as ondas de calor (sintomas vasomotores), insônia, irritabilidade, labilidade emocional, cefaléia, tontura entre outros. Com isso, se as pacientes não fo...
Article
Full-text available
Introdução: A prática de yoga tem se mostrado positiva na redução de insônia. Outros estudos mostram redução de sintomas de climatério. Porém nenhum estudo havia sido realizado até o momento para verificar os efeitos da prática do yoga em mulheres na pós-menopausa com diagnóstico de insônia. Objetivo: avaliar o efeito da prática de Yoga como um tra...
Article
Physiological and psychological alterations in the climacteric period frequently influence women's quality of life. Hot flushes, nocturia, mood alterations, respiratory disturbances, insomnia and restless leg syndrome all affect sleep, and the altered hormonal state in this period impacts the aging process. As hormonal therapy is not indicated in s...
Article
Menstrual pain is a common problem in women of reproductive age and often interferes with the ability to work and with general well-being. Because painful conditions frequently affect sleep, we investigated the impact of this menstrual disorder on sleep patterns in adult women. Additionally, we examined whether medications used to alleviate menstru...
Article
Full-text available
The practice of yoga has been proven to have positive effects on reducing insomnia. Studies have also shown its effects on reducing climacteric symptoms. To date, however, no studies that evaluate the effects of yoga on postmenopausal women with a diagnosis of insomnia in a randomized clinical trial have been conducted. The aim of this study was to...
Article
Full-text available
The aim of this study was to identify factors that most influence the perception of sleep quality in postmenopausal women. We used the methodological strategy of the Collective Subject Discourse (CSD), which is based on a theoretical framework of social representations theory. We obtained the data by interviewing 22 postmenopausal Brazilian women w...
Article
Full-text available
In this article, we provide a concise review of the literature on nocturia and its interference with sleep and, consequently, on quality of life. There are few studies addressing the possible influences of nocturia on sleep disruption. Nocturia is a potential contributor to sleep disorders because affected individuals experience nonrestorative slee...
Article
Testosterone has been the focus of several investigations and review studies in males, but few have addressed its effects on sleep and sexual function, despite evidence of its androgenic effects on circadian activity in both sexes. Studies have been conducted to understand how sleeping increases (and how waking decreases) testosterone levels and ho...
Article
To evaluate sleep quality among women using 2 different types of sanitary pad. Seventeen women (18-40 years) with menstrual cycles of 28-30 days and self-reported moderate-to-intense menstrual flow were enrolled in a crossover study from March to August 2009 in Sao Paulo, Brazil. Sleep assessments were made by polysomnography and by means of valida...
Article
Full-text available
Sleep architecture and polysomnographic findings show that the majority of sleepwalking episodes occur during slow-wave sleep (SWS).1–4 Although genetics play an important role in the manifestation of sleepwalking,5,6 recent studies have shown that parasomnias are also associated with other sleep or mental disorders3,7,10,11 and psychological facto...
Article
Most postmenopausal women have insomnia. Some of these women also have respiratory sleep disorders. Recent reports have documented that the phytohormones, isoflavones, are capable of reducing the symptoms of climacterium. The purpose of this investigation was to examine subjective and objective sleep parameters and to measure changes in these param...
Article
Full-text available
Nearly 80% of women going through menopause experience some kind of clinical symptom and in 40% of cases the symptoms are sufficiently intense to lead the patient to seek medical assistance.1 The most common symptoms are vasomotor instability, nervousness, anxiety, irritability, depression and insomnia, all significantly detrimental to well-being....
Article
Full-text available
As insomnia is highly prevalent, and side effects of medication are well-known, mind-body interventions are increasingly being sought. The objective of this study is to present a narrative review regarding the effects of mind-body interventions for the treatment of insomnia. A PubMed search was conducted including only randomized, controlled trials...
Article
Female sexual dysfunction (FSD) is a complex and multifactorial condition. An increased incidence of FSD is especially associated with the decline of estrogen. Thus, menopause is a critical phase for FSD complaints. In this context, medicinal plants may be a therapeutic option. To identify and describe the popular and clinical uses of medicinal pla...
Article
Full-text available
Hormone decline is common to all women during aging and, associated with other factors, leads to cognitive impairment. Its replacement enhances cognitive performance, but not all women present a clinical and family or personal history that justifies its use, mainly women with a history of cancer. The aim of this study was to determine whether a dai...
Article
The Prospective and Retrospective Memory Questionnaire (PRMQ) has been shown to have acceptable reliability and factorial, predictive, and concurrent validity. However, the PRMQ has never been administered to a probability sample survey representative of all ages in adulthood, nor have previous studies controlled for factors that are known to influ...