Hee Kyun Oh

• Chonnam National University

1. Purpose : This study aimed to investigate the differences in bone regeneration capacity following extraction between a control group without biomaterial placement and experimental groups where biomaterials were inserted (including xenograft, synthetic bone-containing collagen plugs, and collagen plugs).2. Materials and Methods : Bilateral extrac...

Background Relapses following orthognathic surgery have been reported to exceed 2% to 50%, depending on multiple factors. This study aimed to analyze the stability after orthognathic surgery in patients with mandibular ramus height asymmetry through 3D reconstruction using Cone-beam CT. Methods This retrospective cohort study investigated patients...

Closed treatment of mandibular condylar fractures has been used for its indications based on the fracture site, fracture status, and patient age. Posttreatment mandibular condyle size is associated with mandibular function; however, a few studies have reported bone remodeling patterns and volume changes in the condyle and glenoid fossa after mandib...

Background Mandibular condyle remodeling and displacement are post-orthognathic surgery concerns that can potentially lead to occlusal issues after bilateral sagittal split ramus osteotomy. This retrospective study examined the relationship between condylar volume changes and position alterations after surgery in patients with skeletal class II and...

Peri-implantitis is an inflammatory lesion leading to bone destruction resulting from bacterial infection and biofilm formation. Treatments of peri-implantitis aim at bacterial controls and decontamination to promote re-osseointegration. The present study aimed to assess the decontamination of biofilm and the osseointegration of titanium discs in a...

Reactive oxygen species (ROS)-sensitive polymer nanoparticles were synthesized for tumor targeting of an anticancer drug, doxorubicin (DOX). For this purpose, chitosan-methoxy poly(ethylene glycol) (mPEG) (ChitoPEG)-graft copolymer was synthesized and then DOX was conjugated to the backbone of chitosan using a thioketal linker. Subsequently, the ch...

Life-threatening airway obstruction is a major concern in patients with Pierre-Robin sequence. Tongue-lip adhesion (TLA) has been used to manage airway obstruction. The authors present the case of a female neonate with Pierre-Robin sequence who presented with airway obstruction and a cleft palate. She underwent a TLA procedure with modified tongue...

Background: Computer-aided design and manufacturing is widely used in clinical practice. This technology may change existing methods for mandibular fracture management. Purpose: The purpose of this in-vitro study was to determine if the reduction for mandibular symphysis fracture is performed without maxillomandibular fixation (MMF) using 3-dime...

Objectives: Selection of treatment methods for mandibular condylar fractures remains controversial. In this study, we investigated treatment methods for condylar fractures to determine the indications for open or closed reduction. Patients and. Methods: Patients >12 years of age treated for mandibular condylar fractures with a follow-up period o...

Background Recently developed imaging techniques, such as cone beam computed tomography (CBCT) and CAD/CAM technology, have facilitated reliable implant planning and implant surgical guide production by 3D printing. This study compared the accuracy of implant-guided surgery using the R2GATE ® program with CBCT before and after surgery. Patients an...

Purpose The aim of this study was to predict and compare postoperative changes of mandibular position between mandibular setback and advancement surgery in a surgery-first approach (SFA). Materials and Methods The study population included patients who underwent mandibular setback or advancement surgery using bilateral sagittal split ramus osteoto...

The need for the repair of bone defects has been increasing due to various causes of loss of skeletal tissue. High density polyethylenes (HDPE) have been used as bone substitutes due to their excellent biocompatibility and mechanical strength. In the present study, we investigated the preosteoblast cell proliferation and differentiation on the addi...

Background The aim of this multicenter, randomized, open-label, comparative, investigator-blinded study was to investigate the efficacy and safety of recombinant human bone morphogenetic protein 2 (rhBMP-2) combined with β-TCP (rhBMP-2/β-TCP) in alveolar ridge preservation. Materials and methods Eighty-four subjects from three centers were enrolle...

This study aimed to assess the effect of bone buttressing at the vertical osteotomy site on postoperative stability after mandibular setback surgery and determine factors contributing to postoperative relapse. This retrospective study was conducted on patients who received mandibular setback surgery using bilateral sagittal split ramus osteotomy. P...

The purposes of this study were to investigate the influence of the orthodontics-first approach (OFA) and surgery-first approach (SFA) on changes in the signs and symptoms of temporomandibular joint disorders (TMDs) and to compare pre- and postoperative orthodontic treatment duration and total treatment duration between the two approaches. This ret...

Physio-chemical surface properties to biomaterial has been attention in tissue engineering due to their properties on cell adhesion, proliferation, and differentiation. The object of this study is to evaluate the preosteoblast biological response on physio-chemical surface-layered 3D PCL scaffold and 3D PCL/ β -TCP scaffold. 3D scaffolds were fabri...

Purpose This study aimed to assess postoperative bone remodeling after simultaneous sagittal split ramus osteotomy (SSRO) and mandibular angle ostectomy using a three-dimensional (3D) analysis of computed tomography (CT) data. Materials and Methods The authors designed and implemented a retrospective study composed of patients who underwent SSRO w...

Objectives This study aimed to evaluate postoperative changes of condyle after unilateral sagittal split ramus osteotomy (USSRO) and to compare them with changes after bilateral sagittal split ramus osteotomy (BSSRO). Study Design For 50 condyles from 25 patients, positional and volumetric changes of condyle were analyzed using computed tomography...

It is necessary to prevent the invasion of soft tissue into bone defects for successful outcomes in guided bone regeneration (GBR). For this reason, many materials are used as protective barriers to bone defects. In this study, a gellan gum/tuna skin gelatin (GEL/TSG) film was prepared, and its effectiveness in bone regeneration was evaluated. The...

Background: Transverse facial clefts are Tessier's number 7 facial cleft among numbers 1-15 in Tessier's classification of craniofacial malformations, which varies from a simple widening oral commissure to a complete fissure extending towards the external ear. Case presentation: In a patient with a transverse facial cleft, to functionally arrang...

Background: The nasal bone is the most protruding bony structure of the facial bones. Nasal bone fracture is the most common facial bone fracture. The high rate of incidence of nasal bone fracture emphasizes the need for systematical investigation of epidemiology, surgical techniques, and complications after surgery. The objective of this study is...

This case report introduces a treatment in mandibular prognathism correction by combining the surgery-first (SF) approach and clear aligners. An intraoral scanner (TRIOS 3, 3Shape, Copenhagen, Denmark) and a virtual setup program (OrthoAnalyzer, 3Shape) were used for treatment simulation. All clear aligners were fabricated using a 3-dimensional pri...

Background: The incidence of septic arthritis of the shoulder joint is increasing as the population ages. The prevalence of shoulder infection is also increasing because of the growing use of arthroscopy and expansion of procedures in the shoulder. However, cultures do not always identify all microorganisms, even in symptomatic patients. The incid...

Background Fractures of the orbital wall are mainly caused by traffic accidents, assaults, and falls and generally occur in men aged between 20 and 40 years. Complications that may occur after an orbital fracture include diplopia and decreased visual acuity due to changes in orbital volume, ocular depression due to changes in orbital floor height,...

Purpose: The aim of this study was to compare postoperative positional changes in the mandible after isolated mandibular surgery (IMS) or bimaxillary surgery (BMS) in a surgery-first approach (SFA). Materials and methods: The authors designed and implemented a retrospective cohort study composed of patients who underwent mandibular setback surge...

Objectives To evaluate corrective outcome and transverse stability after orthognathic surgery via a surgery-first approach (SFA) in mandibular prognathism with and without facial asymmetry using three-dimensional analysis. Study Design Twenty-nine patients who received mandibular setback surgery using SFA were divided into two groups according to...

Purpose: This study was conducted to investigate the gender- and dental education-specific differences in perception of facial attractiveness for varying ratio of lower face contour. Methods: Two hundred eleven students (110 male respondents and 110 female respondents; aged between 20-38 years old) were requested to rate facial figures with alte...

Background Osteochondroma is a benign tumor that tends to develop in mandibular condyle and coronoid process in the craniofacial region. If tumor mass has grown from condyle into the infratemporal space with zygomatic arch obstructing the access, there are risks associated with surgical exposure and local resection of these masses. Case presentati...

Background Displacement of dental implants into the maxillary sinus is rare, but it primarily occurs in patients with severe pneumatization of the maxillary sinus and/or deficiency of the alveolar process. Some complications such as the infection of the paranasal sinuses and formation of the oroantral fistula can be followed by the displacement of...

Objectives: To evaluate horizontal changes of the proximal mandibular segment after mandibular setback surgery using 3-dimensional computed tomography (3-D CT). Study design: This study included 66 patients who underwent bilateral sagittal split ramus osteotomy for correction of mandibular prognathism. With the use of 3-D CT data obtained preope...

Objective: This study aimed to provide average of standard values in planning orthognathic surgery in Asians. Materials and methods: Thirty-three Asians with well-balanced facial profile, combined with class I occlusion and stabilized condylar head were evaluated using lateral cephalograms. Results: Facial length (Nasion'-Menton') was 138.8 an...

Objectives: This study aimed to evaluate changes in condylar position after bilateral sagittal split ramus osteotomy (BSSRO) with and without Le Fort I osteotomy via the surgery-first approach (SFA) in patients with facial asymmetry. Study design: Eighteen patients (36 condyles) who received surgical-orthodontic treatment using the SFA were incl...

This study was performed to evaluate their 5-year survival rates and identify the factors affecting the prognosis of oral cancer patients who had undergone surgical treatment only. Among 130 patients who were diagnosed with malignant tumor of oral, maxillofacial, and surgical treated in the Department of Oral and Maxillofacial Surgery at Chonnam Na...

Background The purpose of this retrospective study was to evaluate the clinical utility of an implant with a sandblasted, large-grit, acid-etched (SLA) surface and internal connection. Methods Six patients who received dental implants in the Department of Oral and Maxillofacial Surgery, Chonnam National University Dental Hospital, were analyzed by...

Background The aim of this study was to evaluate the clinical outcomes of implants that were placed within the maxillary sinus that has a perforated sinus membrane by the lateral window approach. Methods We examined the medical records of the patients who had implants placed within the maxillary sinus that has a perforated sinus membrane by the la...

Objective: This study was designed to analyze the morphometric characteristics of the orbital cavity using three-dimensional computed tomography in Asians. Methods: Two hundred seventy-six orbits in 142 Asians (74 men and 68 women) were examined and compared according to age, sex, and laterality (right and left). Results: Mean orbital morphome...

Purpose: To examine and compare the 3-dimensional (3D) postoperative changes of the condylar position after mandibular setback surgery using the orthodontics-first approach (OFA) and surgery-first approach (SFA). Materials and methods: This retrospective cohort study included patients who had undergone bilateral sagittal split ramus osteotomy fo...

Objectives: This study aimed to compare preoperatively predicted rotational relapse with actual post-treatment mandibular position after mandibular setback surgery via the surgery-first approach and to evaluate the effect of the increase of vertical dimension (VD) on surgical occlusion and the amount of mandibular setback on postoperative mandibul...

Purpose: This study aimed to identify risk factors associated with bad splits during sagittal split ramus osteotomy by using three-dimensional computed tomography. Methods: This study included 8 bad splits and 47 normal patients without bad splits. Mandibular anatomic parameters related to osteotomy line were measured. These included anteroposte...

The purpose of this study was to investigate implant-supported restoration as a technique for restoring missing teeth in patients with aplastic anemia. Recurrent bleeding from wound sites leads to persistent release of iron in the tissue. Excessive iron in tissue is related to clinical findings, including fibrosis, poor wound healing, and high leve...

Purpose: Elderly people are thought to be more susceptible to periodontal disease due to reduced immune function associated with aging. However, little information is available on the nature of immune responses against putative periodontal pathogens in geriatric patients. The purpose of this study was to evaluate the serum IgG antibody responses t...

Background: This study was performed to evaluate three-dimensional positional change of the condyle using three-dimensional computed tomography (3D-CT) following unilateral sagittal split ramus osteotomy (USSRO) in patients with mandibular prognathism. Methods: This study examined two patients exhibiting skeletal class III malocclusion with faci...

This study examined a female patient with a lower edentulous state, who had undergone a previous alveolar distraction. A lingually malpositioned segment was found after the alveolar distraction. Therefore, an osteotomy of the distracted segment was performed and the segment was corrected into the labial side and fixed with miniplates. Good results...

The mucocele on the inferior orbit is infrequent. When there is occurrence on the inferior orbit, the infraorbital approach, such as transantral, subciliary approach is used commonly. But because of some side effects, the authors use transantral approach intraorally. A 26-year-old woman visited our department with complaint of palpable mass. Comput...

The purpose of this study was to evaluate the effect of the periosteum attached to an iliac block bone graft on resorption of the grafted bone. Twenty-one rabbits were used. Iliac bone was harvested with (experimental group) or without a periosteum (control group) and grafted on the rabbit calvarium and fixed with miniscrews. The animals were kille...

Purpose: This study was performed to evaluate the effect of chitosan combined with absorbable gelatin compressed sponge on the expression of osteoblastic differentiation marker genes during the healing of rat extraction socket. Materials and Methods: Twenty-four male Wistar rats were used. In control group, the extraction socket was closed with sut...

Salivary stones in the parotid gland can be treated with a wide range of methods. Stones close to the opening of the duct can be easily removed through the oral cavity, whereas the entire salivary gland may need to be removed if stones are located close to the parotid gland. In such cases, surgical removal of the parotid gland may be lengthy and ma...

Aptamers are composed of single stranded oilgonucleotides which can selectively bind desired molecules. In 1980s, Thomas Cech reported that RNA or DNA could play as not only a genetic messenger but also a catalyst in metabolic pathways. RNA aptamers (average sizes 40-50 bp) are smaller than antibodies and have strong binding capacities to target mo...

Purpose . We suggest a successful and simple Medpor treated way with chitosan and evaluate more improved osseointegration ability of it than the orignal. Materials and Methods . Medpor was punched into circular shape and dipped into the chitosan gel solution. The Medpor plates soaked with chitosan were identified by the SEM images. We evaluated the...

Purpose: The purpose of this study was to conduct radiographic comparison of maxillary septa in dentulous and edentulous patients using 3-dimensional cone-beam computed tomography (CBCT). Materials and methods: From November- 2008 to August 2010, the CBCT of full dentulous 100 patients was conducted randomly at the Department of Radiology, Chonn...

We investigate the bone generation capacity of recombinant human bone morphogenetic protein-2 (rhBMP-2) immobilized Medpor surface through acrylic acid plasma-polymerization. Plasma-polymerization was carried out at a 20 W at an acrylic acid flow rate of 7 sccm for 5 min. The plasma-polymerized Medpor surface showed hydrophilic properties and posse...

Objectives The purpose of this study was to evaluate several different facial soft tissue measurement methods. Materials and methods After marking 15 landmarks in the facial area of 12 mannequin heads of different sizes and shapes, facial soft tissue measurements were performed by the following 5 methods: Direct anthropometry, Digitizer, 3D CT, 3D...

Few dental procedures are potentially life-threatening. Note, however, that a dental extraction can result in preventable death. Severe post-extraction bleeding can occur, which may give rise to an alarming situation if there is any delay in detecting and managing the problem. The most immediate danger for a healthy patient with severe post-extract...

Background To compare the different resorption patterns between resorbable membrane barrier and periosteum after iliac block bone grafting radiographically and histologically. Methods Eighteen mature male rabbits weighing from 2.0 to 2.5 kg were used. The recipient site was the rabbit skull, and autogenous iliac bone was used as the grafting mater...

Purpose: The purpose of this study was to evaluate the survival and success rates of Korean Osstem implants US II Plus, GS II following loading period. Materials and Methods: Dental records were obtained in total 201 patients who were treated with Korean Osstem implants US II Plus, GS II on both maxillary and mandibular anterior and posterior areas...

The aim of this study was to evaluate the surface properties and in vitro bioactivity to osteoblasts of magnesium and magnesium-hydroxyapatite coated titanium. Themagnesium (Mg) and magnesium-hydroxyapatite (Mg-HA) coatings on titanium (Ti) substrates were prepared by radio frequency (RF) and direct current (DC) magnetron sputtering.The samples wer...

At present, information regarding periodontal disease in geriatric patients is scarce. The purpose of this study was to quantify the periodontal pathogens present in the saliva of Korean geriatric patients and assess the relationship between the bacterial levels and the periodontal condition. Six putative periodontal pathogens were quantified by us...

This retrospective study was performed to evaluate the clinical impact of diabetes mellitus on the prognosis in secondary space infection. Medical records, radiographic images, computed tomography, and microbial studies of 51 patients (25 diabetic patients and 26 non-diabetic patients) were reviewed. Patients were diagnosed as secondary fascial spa...

Purpose This study was conducted to find out the factors affecting the prognosis in oral cancer patients undergone surgical treatment by evaluation on lymph node metastasis, recurrence or distant metastasis, and postoperative therapy. Material and methods Review of medical record and radiographs on the 89 patients who underwent surgical treatment...

Purpose The aim of this study was to describe a method for secondary repair of maxillectomy defects. Material and methods The patients underwent secondary repair of palatal defect following maxillectomy from March, 2007 to September, 2011. They were 4 men and 1 woman, and their ages were ranged 19–70 years (mean 50 years). Partial maxillectomy or...

Purpose We are to report cases of dental rehabilitation with distraction osteogenesis (DO) and dental implant in patients of oral cancer which involved mandible and review of results. Materials and methods Patients who received DO and dental implant treatments were selected for evaluation among the oral cancer patients and their medical records an...

Maxillectomy leaves oronasal and oroantral defects that result in functional impairment of mastication, deglutition, and speech. Many treatment options are suggested and tried including the palatal flap as local flap. Although palatal flaps have been used to repair various oral cavity defects, they have certain limitations due to the dimensions. Th...

urpose : The purpose of this study was to evaluate the US II plus/GS II Osstem(R) implants through the study for the clinical success rate during the installation of the Osstem¢Á implants after bone graft. Materials and Methods : This study was researched in the 4 medical institutions: Chonnam National University, Chosun University, Bundang Seoul N...

To analyze the success and survival rates of the Osstem GSII (Osstem, Busan, Korea) implant in type IV bone. A prospective, multicenter (5 centers) study was conducted by examining the relationship between implant success and survival rates, and several patient and surgical parameters. The implants were placed in 82 patients who visited several nat...

Introduction: The purpose of this study is to evaluate the clinical results of vertical alveolar ridge augmentation using autogenous block bone graft, especially resorption rate, and outcomes of dental implants placed in the grafted site. Patients and Methods: Medical records and radiographs were reviewed. Twenty-seven patients who have been receiv...

This study was conducted to evaluate ssrA expression resulting from adaptation of Escherichia coli (E. coli) to oral pathogens through signal exchange.

Purpose: This research sought to determine the resorption rate of bone grafted to the maxillary sinus according to the grafted material's type, patient's age, systemic disease, implant size, site of implant placement, and residual ridge height. Materials and Methods: This research targeted 24 patients who had immediate Osstem implant (US Plus) plac...

Purpose: This study evaluated the pharyngeal airway space changes in CT images in patients receiving bilateral sagittal split osteotomy (BSSRO) for the surgical correction of mandibular prognathism. Methods: A total of 22 patients with mandibular prognathism were treated using BSSRO. Computed tomography was performed 1 month (T0) before surgery and...

The purpose of this study was to evaluate the clinical result of vertical alveolar distraction, especially the distracted alveolar bone and installed implants.

This study examined the effect of recombinant human bone morphogenetic protein (rhBMP)-2 and β-tricalcium phosphate (β-TCP) on new bone formation in a rabbit calvarium using a rapid prototype titanium cap (RP Ti cap).

This study examined the effect of a conservative neck dissection in patients with head and neck cancer.

This study examined the effects of the conditions for AC-type microarc oxidation (MAO) and the type of hydrothermal treatment solution on the characteristics of hydroxyapatite(HAp)-containing oxide films deposited on commercially pure titanium (CP–Ti). The MAO treatments were carried out in an electrolyte containing 0.2 M calcium acetate monohydrat...

The purpose of this study is to evaluate the effect of platelet rich plasma in bone formation and osseointegration of implant installed in the bone marrow space.

This study examined the effect of cyclosporine A (CsA) on the allogenic cranial bone graft in the mice.

Bone resorption is a unique function of osteoclasts. Osteoclasts are a specialized macrophage polykaryon whose differentiation is regulated principally by macrophage colony-stimulating factors, receptor activator of nuclear factor κB ligand (RANK) ligand, osteoprotegerin (OPG), and interleukins (IL). Reflecting the integrin-mediated signals, osteoc...

The objective of this study was to evaluate the peri-implant's hard and soft tissue response associated with the 1-stage, nonsubmerged, endosseous dental implant. A multicenter retrospective clinical evaluation was performed on 339 nonsubmerged implants placed in 108 patients at 5 clinical centers between January 2003 and December 2007. After a mea...

(-)-Epigallocatechin-3-gallate (EGCG), a major green tea polyphenol, was tested for in vitro cytotoxicity against human laryngeal epidermoid carcinoma of the larynx Hep2 cells. EGCG-induced apoptotic cell death accompanied by a change in the cell cycle. However, EGCG did not result in caspase activation, nor did a caspase inhibitor block cell death...

The present study was undertaken to evaluate our recent experience with mandibular osteoradionecrosis (ORN) and to identify factors that contribute to its progress. The medical records of 114 patients who had been treated for ORN during a 16-year period (1989 to 2004) were reviewed. The patients were then divided into 2 groups according to their re...

In this study we discuss how to control and maintain the vector of the malpositioned segment, which had occurred in post-distraction, and suggested treatments. We studied a patient who had undergone alveolar distraction osteogenesis and revealed a complication at the end of the distraction period; namely, the malpositioned segment. We treated this...

Infraorbital blow-out fracture (IOBF) is an uncommon midfacial trauma, and impairs eyeball function and causes esthetic problems. The extraoral approach can lead to some complications such as scarring, ectropion, and entropion. The intraoral approach, such as a transantral approach, has advantages such as no visible scaring, it can be used to simul...

Purpose : This study was designed to evaluate the clinical aspect of cysts which arised in the oral and maxillofacial region. Patients and Methods : We reviewed clinical record, radiograph, histopathologic and operative report of 155 patients who had been diagnosed as cysts and treated at the department of oral and maxillofacial surgery in Chonnam...

Purpose : This research evaluates the effect of the use of absorbable membrane barrier with deproteinized bovine bone (Bio-, Switzerland) on bone healing in surgically created critical-sized defects in rat calvaria. Materials and Methods : Two standardized transosseous circular calvarial defects (5 mm in diameter) are made in each calvarium of 30 r...

Glycyrrhiza uralensis (Leguminosae) has long been known as an antiinflammatory agent for gastric ulcers, arthritis, and rheumatism. The flavonoid glycyrol (GC) (10 microg/ml) isolated from G. uralensis dramatically inhibits phorbol ester (phorbol 12-myristate 13-acetate)-induced nuclear factor (NF)-kappaB-dependent transcriptional activity, as dete...

Epigallocatechin-3-gallate (EGCG) is a major constituent of green tea polyphenols. This study was aimed to investigate the possible mechanisms of EGCG-mediated inhibition against apoptosis in rat pheochromocytoma PC12 cells by exposure to CoCl(2). Exposure to CoCl(2) caused the generation of ROS and induced cell death with appearance of apoptotic m...

This study was performed to compare the risk of osteoradionecrosis (ORN) in head and neck cancer patients in whom 1 or more impacted third molars were extracted before radiotherapy with patients whose impacted third molars were left intact. Eighty-one patients were selected from the medical records from 1989 to 1998. Patients had at least 1 impacte...

The purpose of this study was to evaluate the effect of adventitial stripping methods on patency and thrombus formation at microvascular anastomoses in the femoral artery of rabbits. The experimental ani- mals were divided into 3 groups according to stripping methods: In Control group, arterial adventitia was not stripped at microvascular anastomos...