Hector Miras

Hector Miras
Hospital Universitario Virgen Macarena · Department of Medical Physics

MS

About

29
Publications
4,164
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148
Citations

Publications

Publications (29)
Article
Background In this study, we evaluate the accuracy, efficiency, and cost-effectiveness of large language models in extracting and structuring information from free-text clinical reports, particularly in identifying and classifying patient comorbidities within oncology electronic health records. We specifically compare the performance of gpt-3.5-tur...
Preprint
BACKGROUND In this study, we evaluate the accuracy, efficiency, and cost-effectiveness of large language models in extracting and structuring information from free-text clinical reports, particularly in identifying and classifying patient comorbidities within oncology electronic health records. We specifically compare the performance of gpt-3.5-tur...
Preprint
Full-text available
Objectives: Explore the potential of Large Scale Language Models (LLMs) to improve the organization of data in clinical reports, with a particular focus on the identification and classification of history and comorbidities in the electronic medical records of oncology patients in the Hospital. Virgin Macarena of Seville. We specifically evaluate th...
Preprint
Full-text available
Genomic stability maintenance requires the repair of DNA breaks in the most accurate fashion. So, an exquisite regulatory network controls the choice between different repair mechanisms to maximize genome integrity. This relies mostly at the level of DNA end resection, the initial steps of the homologous recombination. On the other hand, most cellu...
Article
Full-text available
Ru/Rh asymmetric plaques for ophthalmic brachytherapy have special geometric designs with a cutout intended to prevent irradiation of critical ocular structures proximal to the tumor. In this work, we present new geometric models for PENELOPE + PenEasy Monte Carlo simulations of these applicators, differing from the vendor-reported geometry, that b...
Article
Full-text available
Purpose There is a growing trend towards the adoption of model‐based calculation algorithms (MBDCAs) for brachytherapy dose calculations which can properly handle media and source/applicator heterogeneities. However, most of dose calculations in ocular plaque therapy are based on homogeneous water media and standard in‐silico ocular phantoms, ignor...
Article
Purpose We introduce a system devoted to automatically produce structured data in radiotherapy to: (i) relate clinical outcomes with any variable; and (ii) optimize resources and procedures. Methods and material We have designed a detailed workflow for a patient to follow during radiotherapy treatments. Four elements of Oncology Information System...
Poster
Full-text available
SBAP es un método automatizado dedicado a la optimización de planes de IMRT. Mediante un script, se construyen ROIs o estructuras auxiliares internas (capas) y externas (anillos), a las que se asignan objetivos dosis-volumen (DVH).
Article
Full-text available
La película radiocrómica es un detector ampliamente usado en la verificación de tratamientos en radioterapia. Para su lectura, se emplean escáneres que introducen artefactos espaciales. El propósito de este trabajo es caracterizar y corregir estos artefactos, apreciables no sólo en la dirección lateral, sino también en la dirección longitudinal. Pa...
Poster
Full-text available
Presentation of an automated paperless operating model for a radiotherapy department that makes use of advanced features of the Elekta Radiation Oncology Information System MOSAIQ®.
Article
Full-text available
Background A new implementation has been made on CloudMC, a cloud-based platform presented in a previous work, in order to provide services for radiotherapy treatment verification by means of Monte Carlo in a fast, easy and economical way. A description of the architecture of the application and the new developments implemented is presented togethe...
Article
Full-text available
Purpose: To report the clinical implementation of a novel external beam radiotherapy technique for accelerated partial breast irradiation treatments based on combined electron and photon modulated beams radiotherapy (MERT+IMRT) with conventional MLC. Materials and methods: A group of patients was selected to test the viability of the technique....
Poster
Full-text available
CloudMC, a Cloud Computing application for fast Monte Carlo treatment verification
Article
Purpose: We have developed an inhouse algorithm for the multileaf collimator (MLC) geometry model construction with an appropriate accuracy for dosimetric tests. Our purpose is to build a complex type of MLC and analyze the influence of the modeling parameters on the dose calculation. Methods: Using radiochromic films as detector the following t...
Article
Purpose: We have developed an inhouse algorithm for the multileaf collimator (MLC) geometry model construction with an appropriate accuracy for dosimetric tests. Our purpose is to build a complex type of MLC and analyze the influence of the modeling parameters on the dose calculation. Methods: Using radiochromic films as detector the following test...
Article
Introduction Protons beams are largely used for tumor therapy thanks to their property of delivering dose in a small localized area (Bragg peak). The 3 MV Tandem accelerator at CNA allows to perform measurements with low energy protons. By degrading passively the beam energy, we can study the dosimetry at the end of the range in tissue of therapeut...
Article
Full-text available
One of the major advantages of proton or ion beams, applied in cancer treatment, is their excellent depth-dose profile exhibiting a low dose in the entrance channel and a distinct dose maximum (Bragg peak) near the end of range in tissue. In the region of the Bragg peak, where the protons or ions are almost stopped, experimental studies with low-en...
Poster
Purpose We present the results from a clinical trial of accelerated partial breast irradiation (APBI), using mixed modulated photon and electron beams (MERT+IMRT) with the same photon multileaf collimator (xMLC). Methods Seven patients were enrolled in the first year of the APBI clinical trial. Patients were selected following the conditions inclu...
Conference Paper
Full-text available
CloudMC is a cloud-based platform designed for performing Monte Carlo (MC) simulations in a fast and economical way. Microsoft cloud (Microsoft Azure) works with virtual machines called roles that are classified in different sizes: extra-small, small, medium, large and extra-large. CloudMC architecture consists of a web role, which hosts the web ap...
Article
Purpose: The authors present a hybrid direct multileaf collimator (MLC) aperture optimization model exclusively based on sequencing of patient imaging data to be implemented on a Monte Carlo treatment planning system (MC-TPS) to allow the explicit radiation transport simulation of advanced radiotherapy treatments with optimal results in efficient...
Article
This study evaluates the dosimetric impact caused by an air cavity located at 2 mm depth from the top surface in a PMMA phantom irradiated by electron beams produced by a Siemens Primus linear accelerator. A systematic evaluation of the effect related to the cavity area and thickness as well as to the electron beam energy was performed by using Mon...
Article
Full-text available
This work presents CloudMC, a cloud computing application-developed in Windows Azure®, the platform of the Microsoft® cloud-for the parallelization of Monte Carlo simulations in a dynamic virtual cluster. CloudMC is a web application designed to be independent of the Monte Carlo code in which the simulations are based-the simulations just need to b...
Article
PURPOSE: To simulate the Bebig model I125.S16 source and obtain AAPM Task Group Report 43 brachytherapy dosimetry parameters for comparison to consensus and previously published values. The seed model will then be incorporated into a Monte Carlo model of COMS eye plaques and simulation results will be used for seed-carrier set modeling in a commerc...
Article
To date no detector can offer the unbeatable characteristics of film dosimetry in terms of spatial resolution and this is why it has been chosen by many institutions for treatment verification and, in that respect, radiochromic films are becoming increasingly popular due to their advantageous properties. It is the aim of this work to suggest an eas...

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