Hebat Allah Ahmed Amin

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Verified

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• MD pathology
• Professor (Assistant) at Helwan University

3-Nitropropionic acid (3-NP)-induced neurotoxicity is an experimental model which mimics the pathology and motor abnormalities seen in Huntington's disease (HD) in human. The present investigation was directed to estimate the role of rho kinase (ROCK) inhibition in the possible protective effect of fasudil and simvastatin in 3-NP-induced striatal n...

BACKGROUND: The gathered archeopathological evidence has confirmed that Schistosomiasis has been endemic in Ancient Egypt for over 500 decades. The association between Schistosoma hematobium and increase bladder cancer risk is also well acknowledged. However, over the years, there is a proved changing pattern of bladder cancer that needs to be inve...

The medical education system is currently facing robust challenges as a consequence of the COVID‐19 pandemic. One of them is the maintenance of interactive learning techniques such as Team‐Based Learning (TBL). TBL is an interactive teaching method that is learner‐centered and instructor‐directed. It sequentially involves self‐work followed by team...

The sudden, prolonged COVID-19 lockdown has offered a great challenge to the medical school. This was not only at the level of learning and curricular design but also the level of assessment. The traditional summative assessment tools have collapsed during this Pandemic. Herein, we provide a five-step guide for designing competency-based E-assignm...

Bone marrow embolism (BME) is likely a consequence of fractures in which pulmonary vessels are the most affected. However, some cases of BME were reported in the absence of trauma. Thus, a traumatic injury might not be necessary for developing BME. This study discusses BME cases in patients without signs of fractures or blunt trauma. The discussion...

Background Huntington’s disease (HD) is a progressive neurodegenerative disease that causes motor, cognitive, and psychiatric abnormalities, with no satisfying disease-modifying therapy so far. 3-nitropropionic acid (3NP) induces behavioural deficits, together with biochemical and histological alterations in animals’ striata that mimic HD. The role...

Background Culture is an essential component that governs all aspects of human behavior. Superstition is an irrational belief observed in almost all cultures. It is linked to one or more factors like supernatural powers, good luck, bad omen, fiction, illegitimate activity, absurd narration, folk tales, or practice without any rational basis. Metho...

Background: Sudden unexplained deaths present challenges for forensic pathologists as they do not deal only with traumatic deaths, but also with a wide range of natural deaths. These are mostly sudden, unexpected, clinically unexplained, or otherwise obscure deaths. The cardiovascular disorders being a primary focus is the leading cause of sudden u...

Background Human autopsy is widely used to investigate and confirm the causes of death. Commonly reported cases involve the cardiovascular and cerebral systems. However, human autopsy practices have been restricted due to ethical and religious implications in many countries.AimThe study aims to know if using human autopsy techniques on animal model...

Background/aim Breast carcinoma is a worldwide, heterogeneous disease that affects even the young patient population. The receptor tyrosine kinase mesenchymal–epithelial transition factor (c-Met) is suggested to be associated with reduced survival in cases of breast cancer. Few studies have specifically addressed the association between the c-Met a...

This study aimed to evaluate the potential neuroprotective effects of ketogenic diet (KD) against the neuronal disruptions induced by SE in lithium‐pilocarpine rat model of status epilepticus (SE). Four groups of female rats include; groups I and III received standard diet and groups II and IV received KD for 3 weeks. Groups I and II were left untr...

Background Students’ anxiety due to the COVID-19 pandemic was expressed by some medical students in the form of anger and mistrust. This study aims to explore the reasons for mistrust between students and faculty among medical schools in Egypt that have flared during the pandemic. Methodology This is a three-phase exploratory qualitative study dep...

Acute myocardial infarction (AMI) remains a leading cause of morbidity and mortality worldwide. Lutein (LU) possesses numerous pharmacological activities, including anti‐inflammatory, antioxidant, and antiapoptotic effects. This study aimed to investigate the cardioprotective potential of LU in isoprenaline (ISO)‐induced MI and to explore its molec...

Background There is an urgent need for more diverse methods for student evaluation, given the sudden shift to online learning necessitated by the coronavirus disease 2019 (COVID-19) pandemic. Innovative assessment tools will need to cover the required competencies and should be used to drive self-learning. Self-assessments and peer assessments may...

Background: Maternal deaths are quite common tragic event in developing countries where the main source of information on the causes of maternal death is clinical records and autopsies. Knowledge about the causes of these deaths are scarce in Egypt. Efforts to reduce maternal mortality in Egypt are mostly not driven by evidence. This autopsy study...

Purpose: Faculty development activities have been designed to enhance teacher performance at all professional levels. The work aimed to evaluate the faculties' suggestions for improvement of their academic knowledge and skills in addition to their recommendation about the factors influencing the effectiveness of the faculty development program. Met...

In the article titled "Students' Awareness as an Underlying Factor for Satisfaction and Compliance", published on pages 198-204, Issue 4, Volume 8 of Journal of Microscopy and Ultrastructure [1] , the name of the third author name is written incorrectly as "Mostafa M. El Shahed" instead of "Mostafa Yosef ". The "How to cite this article" section sh...

ASU MENA FRI FAIMER Project

Background: Students anxiety due to the COVID-19 pandemic was expressed by some medical students in the form of anger and mistrust. This study aims to explore the reasons for mistrust between students and faculty among medical schools in Egypt that have flared during the pandemic.

Background: Medical education is facing great challenges and uncertainties amidst the COVID-19 pandemic. Aims and objectives: This article aims to provide tips that can provide a guide for medical education leaders to coordinate crisis management referring to the Egyptian context. Materials and methods: This work was done using a reflection on...

Abstract Urinary bladder cancer is a common malignancy in Egypt, thus reliable methodologies are required for screening and early detection. In this study, we analyzed the gene expression of a Schistosoma hematobium specific microRNA “Sha-miR-71a” and mitogen-associated protein kinase-3 (MAPK-3) in the urine samples of 50 bladder cancer patients an...

Benign prostatic hyperplasia (BPH) is a nonmalignant enlargement of the prostate common in older men. Diallyl sulfide (DAS), a major component of garlic, has been reported to possess antioxidant, anti-inflammatory, and antiproliferative effects. However, the underlying protective immunomodulatory mechanism of DAS on BPH remains vague. Herein, exper...

BACKGROUND: Atherosclerosis is a widespread and devastating disease and one of the leading causes of death worldwide. So much is there to understand about atherosclerosis. And although a lot is already discovered, yet most of the studies are performed in cell cultures and animal models. Recent technologies for genetic engineering and imaging are ma...

Background: Implementing case-based learning (CBL) in the Integrated Modular Curriculum has proved a greatefficiency in teaching medical students. We aim to develop and validate a customized model of CBL to integratedisciplines while meeting the requirements of our national academic reference standards. Phase I medical students’reflection is presen...

There is an urgent need for more diverse methods for student evaluation, given the sudden shift to online learning necessitated by the Coronavirus Disease 2019 (COVID-19) pandemic. Innovative assessment tools will need to cover the required competencies and should be used to drive self-learning. Self and peer assessments may be added to the traditi...

As soon as the WHO declared COVID-19 a pandemic, many higher education facilities had to change their educational and teaching strategies to cope with the lockdown. Some medical schools decided to rely on online teaching while others depended on students self-learning abilities. Methods of assessment also changed as some medical schools implemented...

Students’ anxiety due to the COVID-19 pandemic was expressed by some medical students in the form of anger and mistrust. This study aims to explore the reasons for mistrust between students and faculty among medical schools in Egypt that have flared during the COVID-19 pandemic. This is a three-phase exploratory qualitative study depending on thema...

Background: Implementing case-based learning (CBL) in the Integrated Modular Curriculum has proved a great efficiency in teaching medical students. We aim to develop and validate a customized model of CBL to integrate disciplines while meeting the requirements of our national academic reference standards. Phase I medical students reflection is pres...

Medical education is facing great challenges and uncertainties amidst the COVID-19 pandemic. Medical Education Institutions are required to build a task force team for crisis management. These should be committed to supporting a sudden online education transition, academic support, and psychological well-being of students, staff members, health car...

Role of progenitor cells in atherogenesis

Background Students’ anxiety due to the COVID-19 pandemic was expressed by some medical students in the form of anger and mistrust. This study aims to explore the reasons for mistrust between students and faculty among medical schools in Egypt that have flared during the pandemic. Methodology This is a three-phase exploratory qualitative study...

n Egypt, there is a national concern towards a transition to integrated modern medical educational system. However, the lack of students’ motivation and engagement have been frequently observed and reported. Therefore new strategies should be adopted to improve the quality of education and inspire students and encourage them. This includes imp...

https://www.researchgate.net/profile/Ahmed_Nada9/achievement/5eafbb949b243c96454cf807 https://www.researchgate.net/profile/Ahmed_Nada9/achievement/5eb1025d843996ab47a93ba1

PBL., tutor's orientation. Objectives: Define PBL. Identify the advantages of PBL. Anatomy of the PBL group. Describe the role of the tutor. Describe the role of students including the chairperson and the scribe

What is E-learning? Why is it needed in today's education? Myths and truth about E-learning Challenges in implementing E-learning Application: Pathbrite.com FMHU Platform Pathbrite.com Components of the courses Best practice Students’ participation in the courses material Assignment submission Students’ engagement Students’ feedback How to overcome...

A pilot study was previously performed on the first batch students (2016-2022), where reform of the pathology course has been implemented through an interactive blended e-learning/ CBL modality that aided in the execution of a fairly integrated curriculum and a fairly interactive method. High levels of students’ engagement and satisfaction have bee...

Schistosomiasis is an ancient disease, depicted in papyri from Pharaonic Egypt. WHO (2015) reported schistosomiasis as endemic in 78 countries. It was first linked to urinary bladder cancer by Furgesson in Egypt in 1911. In 2012, IARC (International Agency for Research on Cancer) reeported the association between Schistosomaiasis and cancer of the...

Stem cell therapy represents a promising therapeutic avenue for cardiac disorders, including heart failure. Although stem cell transplantation showed encouraging preliminary results, the outcomes of clinical studies are still unsatisfactory. This study aimed to compare the outcomes of two therapeutic approaches, in vivo co-delivery of sodium hydrog...

Debates in Hepatology and Gastroenterology Fibrosis assessment / Invasive.

Objectives: Appreciate the role of assessment as a critical component for accomplishing key curricular goals Identify the main types of MCQs. Identify item formats, mainly single-best-answer (SBA) format Describe the structure of a good MCQ Recognize technical item flaws and issues related to item content Construct quality SBA MCQs according to NBM...

Background and study aims: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide with highest incidence in Asia and Africa. MicroRNAs (miRNAs), a class of non-coding single stranded RNA, which not only post transcriptionally regulate gene expression but also respond to signaling molecules to affect cell functions such as Wnt/β...

Lymphoepithelioma-like carcinoma (LELC) of the breast is an exceedingly rare variant of mammary cancer. To our knowledge, only twenty - one cases have been reported in the literature. Diagnosis of this type of mammary carcinoma may be challenging, owing to its rarity and the histopathological similarity to common inflammatory and malignant lesions...

Background: Human breast cancers are heterogeneous. This heterogeneity may originate due to differences in the target cell population and/or it may be the result of different combinations of mutations in a normal breast progenitor cell. New therapeutic targets are needed in breast cancer, particularly in patients with TNBC and the related basal-lik...

BACKGROUND: Many immunohistochemical markers have been used in the postmortem detection of early myocardial infarction. AIM: In the present study we examined the role of Heart-type fatty acid binding protein (H-FABP), in the detection of early myocardial infarction. MATERIAL AND METHODS: We obtained samples from 40 human autopsy hearts with/ withou...

Background: Triple negative breast carcinomas (TNBCs) are a group of primary breast tumors with aggressive clinical behavior that have no targeted therapy at present. Comparative studies for subtypes of triple negative group of invasive breast carcinoma are needed to detect any specific morphologic features of this group. Results: The study includ...

Abstract Triple negative breast carcinomas (TNBCs) are a group of primary breast tumors with aggressive clinical behavior that have no targeted therapy at present. Epidermal growth factor receptor (EGFR) expression has recently come into focus as an index for molecular targeting therapy. Histologic sections that included variable subtypes and grad...

The relative contributions of trauma and disease may become a challenging acute medico-legal problem. Discussed here a case of sudden death due to myocardial infarction, associated with an external chest injury. Routine histopathological as well as immunohistochemical examination of the tissue samples using cTnT, MB, desmin and caspase-3 was made t...

Immunohistochemical techniques have proven effective in forensic pathology use as they can be applied to tissue samples fixed in formalin and embedded in paraffin. In this work, we selected a panel of antibodies, desmin, troponin T (cTnT), and myoglobin (MB), for the detection of early myocardial infarction in human autopsy hearts with suspected su...

The current study aimed at investigating the potential hepatoprotective property and mechanism of meloxicam (MEL) against carbon tetrachloride (CCl(4))-induced hepatocellular damage in rats. Subcutaneous administration of CCl(4) (2 mL/kg, twice/week for 8 weeks) induced hepatocellular damage substantiated by hematoxylin and eosin staining and signi...

Background Immunohistochemical techniques have proven to be effective for use in forensic pathology, as they can be applied to tissue samples fixed in formalin and embedded in paraffin. Histologic sections, including ischaemic and non-ischaemic myocardia, were studied via immunohistochemistry with three different antibodies to human cardiac troponi...

This essay is aimed at our pathologists and medical examiners in the hope of convincing them that it is not difficult or time-consuming to remove and fix the brain and spinal cord properly post mortem. We will try to give a quick review for the proper performance of brain autopsy, proper fixation, concise reminders of the forensic anatomy of the br...