Heba Alzer

• DDS. PhD. Stem Cells Biology
• Professor (Associate) of Oral Sciences at University of Jordan

Background: Induced pluripotent stem cells have been proposed as a novel therapeutic option that provides an autologous source of stem cells. However, the methods utilized in generating induced pluripotent stem cells, like viral transduction, ‏and the tumorgenicity of the resulting cells, raise serious concerns in medical society. Objective: Here,...

Background : Despite comprehensive studies and reports about the properties of dental pulp stem cells (DPSCs) in vitro, we still lack the knowledge of whether these in vitro characteristics coincide with the original nature of DPSCs in situ. The histological location of DPSCs populations in the dental pulp has been rarely investigated. Methods : In...

Despite comprehensive studies and reports about the properties of dental pulp stem cells (DPSCs) in vitro, we still need to confirm whether these in vitro characteristics coincide with the nature of DPSCs in situ. The anatomical location of DPSCs populations in the dental pulp has yet to be investigated. Moreover, the mesenchymal DPSCs have been mu...

Objective: Odontoblasts of the dental pulp are considered terminally differentiated cells. We investigated whether these cells express any embryonic, mesenchymal, or neural stem cell markers, along with other previously reported differentiation markers. Methods: An immunohistochemical study was performed on wisdom teeth extracted from healthy donor...

SUMMARY: Despite comprehensive studies and reports about the properties of dental pulp stem cells (DPSCs) in vitro, we still need to confirm whether these in vitro characteristics coincide with the nature of DPSCs in situ. The anatomical location of DPSCs populations in the dental pulp has yet to be investigated. Moreover, the mesenchymal DPSCs hav...

Background Learning fine motor skill is central to preclinical dental education. Dental students are introduced to anatomical tooth carving to facilitate the development of their fine motor skill and manual dexterity. Various carving technique exists, such as wax build-up, and geometric (block carving technique). Since substantial laboratory Time a...

Introduction: To assess patients' satisfaction with the dental care provided to them by the undergraduate students at Jordan University Hospital. In addition, to investigate whether the age or gender of patients had any correlation with the level of satisfaction. Materials and methods: The Dental Satisfaction Questionnaire (DSQ) developed by the...

Objectives: To assess patients' satisfaction with the dental care provided to them by the undergraduate students at Jordan University Hospital. Methods: The Dental Satisfaction Questionnaire (DSQ) developed by the RAND Corporation was used to measure patient satisfaction. The questionnaire was translated to Arabic the native language of the country...

Objectives The dental pulp stem cells (DPSCs) of six donors (three young donors aged < 19 years and three adult donors aged > 25 and < 30 years) were characterized for their stem cell marker expression and differentiation potential to study the effect of donor age on DPSCs in vitro. Methods DPSCs were cultured in αMEM supplemented with 20% fetal c...

Abstract The objectives were to determine the expression frequency and sexual dimorphism of 15 dental morphological traits on the permanent dentitions of living Jordanians, and to compare the dental morphological pattern of this sample with those of 22 groups representing the various geographic regions of the world, for the purpose of assessing th...

The objectives were to determine the expression frequency and sexual dimorphism of 15 dental morphological traits on the permanent dentitions of living Jordanians, and to compare the dental morphological pattern of this sample with those of 22 groups representing the various geographic regions of the world, for the purpose of assessing the populati...

Background/purpose Triple antibiotic paste (TAP) has been successfully used in revascularization procedure. However, one of the problems associated with TAP use is teeth discoloration, which is attributed to the presence of minocycline constituent. The aim of this study is to investigate the discoloration effect of different concentrations of tripl...

The objective was to determine the degree of fluctuating asymmetry in the expression of 13 dental morphological traits among adult Jordanians. Cone beam computed tomography images for the dentitions of 150 adult Jordanians (67 males, 83 females; age range = 18-58, mean ages 28.2, SD = 10.0 years) were studied in 2017. The traits were classified usi...

Estimation of age-at-death is an integral part of the identification process of individuals in many forensic odontology cases where their identity cannot be determined by visualization or other ways. Dental age estimation in the adult is more challenging as most of the dentition is completely developed by 18 years of age. This study employs a mesio...

Background and Objective: Ibuprofen is commonly used to treat various inflammatory pain disorders. Its analgesic properties are attributed mainly to inhibiting cyclooxygenases enzymes and blocking the production of prostaglandins. The aim of this study is to evaluate the role of PPARα and PPARγ in mediating the anti-nociceptive effects of ibuprofen...

The peripheral nervous system (PNS) has an intrinsic ability for repair and regeneration even after severe injury. Peripheral nerve injury is followed by the normal rapid progression of Wallerian degeneration (anterograde or orthograde degeneration). During this process, the distal detached nerve segment degenerates, and the surrounding myelin brea...

Background/aim: As already described in previous studies, neural crest stem cells (NCSCs) can be found in adult human dental pulp. The present study investigated the methodology for enrichment and differentiation-induction of the above mentioned cells. Materials and methods: Dental pulp was extracted from human wisdom teeth of four patients and...