Heba Abdelal

Heba Abdelal
Washington University in St. Louis | WUSTL , Wash U · Department of Pathology and Immunology

About

15
Publications
2,263
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66
Citations
Citations since 2016
12 Research Items
67 Citations
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201620172018201920202021202205101520

Publications

Publications (15)
Article
Intracholecystic papillary-tubular neoplasm denotes a discrete mucosal-based neoplastic proliferation into the gallbladder lumen. It is diagnosed incidentally during cholecystectomy or radiologically during a workup for abdominal pain. The majority of polypoid lesions in the gallbladder are non-neoplastic; therefore, pathologic examination is the g...
Article
Full-text available
Prior reports have shown optical coherence tomography (OCT) can differentiate normal colonic mucosa from neoplasia, potentially offering an alternative technique to endoscopic biopsy - the current gold-standard colorectal cancer screening and surveillance modality. To help clinical translation limited by processing the large volume of generated dat...
Conference Paper
Full-text available
Colorectal cancer is the second most common malignancy diagnosed globally and the 4th leading cause of cancer mortality. Critical gaps exist in diagnostic and surveillance imaging modalities for colorectal neoplasia. We have conducted a pilot study using a real-time co-registered photoacoustic (PAT) and ultrasound (US) tomography system. A total of...
Conference Paper
A pattern-recognition optical coherence tomography was designed to automate diagnosis of human colorectal tissue in real-time. An area under the ROC of 0.998 is achieved by our initial experience with 18 ex vivo human specimens.
Conference Paper
A multi-wavelength spatial frequency domain imaging (SFDI) system combined with AdaBoost classifier was used to automatically classify ex vivo human colorectal tissues. A sensitivity of 89.7% and a specificity of 91.8% were achieved.
Article
Full-text available
Context.— Clinical decision support (CDS) systems could assist less experienced pathologists with certain diagnostic tasks for which subspecialty training or extensive experience is typically needed. The effect of decision support on pathologist performance for such diagnostic tasks has not been examined. Objective.— To examine the impact of a CDS...
Article
Full-text available
Colorectal cancer is the second most common malignancy diagnosed globally. Critical gaps exist in diagnostic and surveillance imaging modalities for colorectal neoplasia. Although prior studies have demonstrated the capability of photoacoustic imaging techniques to differentiate normal from neoplastic tissue in the gastrointestinal tract, evaluatio...
Conference Paper
Full-text available
Schistosomiasis is an ancient disease, depicted in papyri from Pharaonic Egypt. WHO (2015) reported schistosomiasis as endemic in 78 countries. It was first linked to urinary bladder cancer by Furgesson in Egypt in 1911. In 2012, IARC (International Agency for Research on Cancer) reeported the association between Schistosomaiasis and cancer of the...
Conference Paper
Full-text available
Colorectal cancer is the second most common malignancy diagnosed globally. Critical need exists for imaging and diagnosis of rectal tumors for both staging and therapeutic response evaluations. We have conducted a pilot study to image and characterize colorectal masses using a real-time co-registered photoacoustic (PAT) and ultrasound (US) system....
Article
Objectives Conventional intestinal-type dysplasia (CID) is well described in the setting of ulcerative colitis (UC). Other types of dysplasia are less reported. Our aim was to investigate the prevalence and significance of these less known dysplasias in the setting of UC. Methods Colonic resections from UC patients were divided into two cohorts—gr...
Conference Paper
Background: Human breast cancers are heterogeneous. This heterogeneity may originate due to differences in the target cell population and/or it may be the result of different combinations of mutations in a normal breast progenitor cell. New therapeutic targets are needed in breast cancer, particularly in patients with TNBC and the related basal-lik...
Article
Full-text available
The relative contributions of trauma and disease may become a challenging acute medico-legal problem. Discussed here a case of sudden death due to myocardial infarction, associated with an external chest injury. Routine histopathological as well as immunohistochemical examination of the tissue samples using cTnT, MB, desmin and caspase-3 was made t...
Article
Full-text available
Immunohistochemical techniques have proven effective in forensic pathology use as they can be applied to tissue samples fixed in formalin and embedded in paraffin. In this work, we selected a panel of antibodies, desmin, troponin T (cTnT), and myoglobin (MB), for the detection of early myocardial infarction in human autopsy hearts with suspected su...

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