Hazem Almhanna

University of Al-Qadisiyah | UAQ

A network analysis of canonical microRNA (miRNA) biogenesis identified DROSHA, Exportin-5, and DICER1 as essential proteins for both precursor and mature miRNA processing. The analysis revealed strong interactions between these proteins and others involved in miRNA biogenesis, suggesting a complex regulatory network. Ligand binding sites on these k...

Background and Aim In avian and other species, mucins (MUCs) play a crucial role in the gastrointestinal tract (GIT), and constitute a large group of O-glycosylated glycoproteins, are glycoconjugate proteins. MUCs present in two forms: (1) membrane-attached on cell surfaces to repel external threats and (2) detachable, gel-forming proteins in the s...

Background: Newcastle Disease (ND), caused by the Newcastle Disease Virus (NDV) poses a significant threat to poultry, leading to severe economic losses. Understanding the molecular interactions between NDV proteins and avian mucins is crucial for developing targeted interventions. Materials and Methods: In this study, twelve NDV proteins were syst...

Background Sialic acid-binding immunoglobulin-like lectin 1 (Siglec-1) is a transmembrane glycoprotein involved in the sialic acid (Sia)-dependent regulation of the immune system. Siglec-1 expression has recently been identified in the male reproductive tract (MRT) of several species, including humans, cattle, horses, and sheep, and may play a role...

Background: Urinary tract infections (UTIs) are currently posing a worldwide health concern by affecting millions of people. The genetic variant rs2234671 in the CXCR1-interleukin-8 receptor is closely related to a raised UTI risk. Objectives: In this work, the impact of CXCR1 (rs2234671) on UTI individuals was examined. Methods: The demograph...

Background Newcastle Disease (ND), caused by the Newcastle Disease Virus (NDV) poses a significant threat to poultry, leading to severe economic losses. Understanding the molecular interactions between NDV proteins and avian mucins is crucial for developing targeted interventions. Material and Methods In this study, twelve NDV proteins were system...

This study has been conducted to determine the anatomical and histological structures of the kidneys using different anatomical techniques, including topographical dissection, corrosion casting technique, and radiology, in addition to routine and special stains for histology study. Ten healthy adult kidneys of one-humped camels were chosen for diff...

This study has been conducted to determine the anatomical and histological structures of the kidneys using different anatomical techniques, including topographical dissection, corrosion casting technique, and radiology, in addition to routine and special stains for histology study. Ten healthy adult kidneys of one-humped camels were chosen for diff...

This study focused on the powder of the shell of the local garden snail in Iraq to identify the chemical compounds and determine the diversity and biological contents that might be applied for other applications and studies. Thus, snails shell was collected from local rivers in Al Diwaniya city, middle of Iraq; 500 grams of the shell powder of the...

Background This study focused on the major components of mucus, known as mucins, within the mucosal epithelium of the respiratory system in Iraqi Common Quail. Six quail were utilized in accordance with animal ethics guidelines from the College of Veterinary Medicine at the University of Al-Qadisiyah. Histological analysis, utilizing H&E staining,...

Background Mucins have vital pathophysiological role in gastrointestinal tract (GIT) of avian and other species. However, despite this very little is known about the types of mucins expressed in quail GIT. Hence in this study we examined the expression pattern of mucins (MUC1, and MUC4) in the GIT of the Iraqi Common Quail (Coturnix Coturnix) and p...

Siglec-6 is a member of the transmembrane surface proteins (Siglecs) and is expressed in immune cells and on the cell membrane of spermatozoa of human, bovine and horse. This study aimed to identify the potential expression pattern of Siglec-6 orthologues in mice and rats and performed network analysis of Siglec-6 for future comparative medicine ap...

The current study aimed to detect specific types of ADAM proteins in the bovine sperm. Histology study of tissue of male reproduction was involved with testis, head, body, and the tail of the epididymis. Results showed that the testis composed of the parenchyma of testis contained the seminiferous tubules which are surrounded by two layers external...

This study was aimed to identify the anatomical and histological structures of papillary muscles of the right and left sides of bulls' hearts, in relation to the chordae tendineae which are normally extended from papillary muscles. Six hearts of fresh adult bulls were studied grossly and histologically for this research. Anatomical study was conduc...

Background and Aim: Angiotensin-converting enzyme 2 (ACE2) is expressed and plays functional and physiological roles in different tissues of the body. This study aimed to distinguish the levels of expression of ACE2 in the lung tissue at different ages of rats. Materials and Methods: In this study, 18 male rats were used and divided into three gro...

The current study has been conducted on health human sperm to identify the different types of amino acids and entire proteins of sperm. Two methods have been applied to characterise of human sperm, firstly extract lysate of sperm, then digest and run it in mass spectrometry, secondly, total sperm lysate was run in SDS page gel and bands were staine...

The current investigation comprised a histological study of the fourth compartment(abomasum) of a one-humped camel’s stomach in adult animals, which included (5) specimens from adults were used. The histological study of the fourth compartment (abomasum) of the stomach revealed that it was lined with simple columnar epithelium, it was noted that th...

Lead acetate (LA) has been shown to cause hepato-renal damages through induction of oxidative stress. Edible bird’s nest (EBN) has reportedly been shown to alleviate these damages, but no studies have been conducted on this area. The present study was aimed to evaluate the protective effects of EBN supplement on the liver and kidney of rats expos...

This study has been designed to analyse the secreted and soluble proteins in bovine seminal plasma by mass spectrometry. The majority of these proteins are produced by accessory glands, and partially by testis, epididymis, ductus deferens and vas deferens of male reproductive tract. Seminal plasma of bovine was collected freshly and isolated after...

Identifications different types of Siglecs in animals model mice and rats.

Aim: This study aimed to evaluate the protective effect of edible bird's nest (EBN) supplement on the uteri of rats exposed to lead acetate (LA) toxicity. Materials and methods: Five treatment groups were established as follows: Group 1 (C), which was given distilled water; Group 2 (T0), which was administered with LA (10 mg/kg body weight [BW])...

This study was intended to identify the different types of amino acids and whole proteins of the healthy bovine sperm. Two methods applied for characterizing the bovine sperm. Firstly, the whole sperm lysate was extracted and digested and then run in mass spectrometry. Secondly, the total sperm lysate was run in SDS page gel, and then the bands wer...

Sialic acid (Sia) is a major constituent of both the sperm glycocalyx and female reproductive mucosal surface and is involved in regulating sperm migration, uterotubal reservoir formation and oocyte binding. Siglecs (sialic acid-binding immunoglobulin – like lectins) commonly found on immune cells, bind to Sia in a linkage- and sugar-specific manne...

Sialic acid (Sia) is a major constituent of both the sperm glycocalyx and female reproductive mucosal surface and is involved in regulating sperm migration, uterotubal reservoir formation and oocyte binding. Siglecs (sialic acid-binding immunoglobulin - like lectins) commonly found on immune cells, bind to Sia in a linkage- and sugar-specific manne...

Sialic acid (Sia) is a major constituent of both the sperm glycocalyx and female reproductive mucosal surface and is involved in regulating sperm migration, uterotubal reservoir formation and oocyte binding. Siglecs (sialic acid-binding immunoglobulin - like lectins) commonly found on immune cells, bind to Sia in a linkage- and sugar-specific manne...

In the current study, 30 adult male rabbits were used, rabbit was divided into two groups 10 in each group: group(A) was unilateral nephrectomy, while group (B) was partial nephrectomy; also, 10 rabbits were a control group (C). After 15 days 5 rabbit from groups (A, B and C) was killed and the anatomical, histological changes and biochemical analy...

In the current study, ten specimens of the adult ox kidneys have been used to identity morphology and blood supply features by using corrosion cast technique. The mean body weight of ox was 180±10kg. The external surface of the kidneys was elongated oval to pyramid, lobulated flattened ventrodorsally, and light-brown in color. The right kidney is w...

Interaction of bovine sperm with cervical mucins

Formalistic study elucidate that the larynx in the fourteen healthy indigenous male pigeons (Columba domestica) for benefit in the study of the respiratory physiology, histopathology, and the respiratory diseases analyzes. After bird's preparation, the larynx detected, and then the shape, position and its components studied in details.The larynx em...