Hassan M M Ahmed

Hassan M M Ahmed
Georg-August-Universität Göttingen | GAUG · Department of Developmental Biology

Dr. rer. nat.

About

13
Publications
2,110
Reads
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183
Citations
Additional affiliations
April 2014 - December 2016
Georg-August-Universität Göttingen
Position
  • PhD Student
Description
  • Insect develomental biology, Sterile Insect Technique , Insect Transgenesis
Education
August 2008 - August 2011
University of Khartoum
Field of study
  • Genetics & Molecular Biology
October 2000 - October 2005
University of Khartoum
Field of study
  • Agriculture- Entomology

Publications

Publications (13)
Article
Full-text available
Background The invasive fly Drosophila suzukii has become an established fruit pest in Europe, the USA, and South America with no effective and safe pest management. Genetic engineering enables the development of transgene-based novel genetic control strategies against insect pests and disease vectors. This, however, requires the establishment of r...
Chapter
With CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated) scientists working with Tribolium castaneum can now generate transgenic lines with site-specific insertions at their region of interest. We present two methods to generate in vivo imaging lines suitable for marking subsets of neurons with fluorescent prote...
Preprint
Background: The invasive fruit pest Drosophila suzukii was reported for the first time in Europe and the USA in 2008 and has spread since then. The adoption of type II clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) as a tool for genome manipulation provides new ways to develop novel biotechnologically-bas...
Article
Full-text available
Background: The invasive fruit pest Drosophila suzukii was reported for the first time in Europe and the USA in 2008 and has spread since then. The adoption of type II clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) as a tool for genome manipulation provides new ways to develop novel biotechnologically-ba...
Preprint
Background: The invasive fruit pest Drosophila suzukii was reported for the first time in Europe and the USA in 2008 and has spread since then. The adoption of type II clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) as a tool for genome manipulation provides new ways to develop novel biotechnologically-bas...
Preprint
Background: The invasive fruit pest Drosophila suzukii has been reported for the first time in Europe and USA in 2008 and has spread since then. The adoption of type II clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated (Cas) as a tool for genome manipulation has opened the doors for researchers to develop novel bi...
Article
The use of a site-specific homing-based gene drive for insect pest control has long been discussed, but the easy design of such systems has become possible only with the recent establishment of CRISPR/Cas9 technology. In this respect, novel targets for insect pest management are provided by new discoveries regarding sex determination. Here, we pres...
Article
Even in times of advanced site-specific genome editing tools, the improvement of DNA transposases is still on high demand in the field of transgenesis: especially in emerging model systems where evaluated integrase landing sites have not yet been created and more importantly in non-model organisms such as agricultural pests and disease vectors, in...
Poster
In an effort to optimize and use the programmable genome editing system CRISPR/Cas9 for the invasive fruit pest Drosophila suzukii, we cloned and compared the promoters of the three D suzukii U6 genes (A, B, & C) in driving the expression of guide RNA and achieved the highest CRISPR/Cas9 gene editing result using U6C promoter compared to U6B and U6...
Article
Full-text available
The Sterile Insect Technique (SIT) is an accepted species-specific genetic control approach that acts as an insect birth control measure, which can be improved by biotechnological engineering to facilitate its use and widen its applicability. First transgenic insects carrying a single killing system have already been released in small scale trials....

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Projects

Project (1)
Project
We aim to exploit insect transgenesis and genome editing tools to develop ,eco-friendly pest control strategies suitable for agricultural pests as well as insect vectors of human and animal diseases.