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Publications (14)
High altitude characterized by the low partial pressure of the oxygen is a life-threatening condition that contributes to the development of acute pulmonary edema and hypoxic lung injury. In this study, we aimed to investigate the contribution of some inflammatory and oxidative stress markers along with antioxidant system enzymes in the pathogenesi...
The effect of silver nanoparticles (Ag NPs) obtained in the presence of royal jelly (RJ) on the growth of yeast Candida guilliermondii NP-4, on the total and H⁺-ATPase activity, as well as lipid peroxidation process and antioxidant enzymes (superoxide dismutase (SOD), catalase) activity was studied. It has been shown that RJ-mediated Ag NPs have a...
This study investigates the impact of immobilization stress as a risk factor for pathological processes, with a focus on erythropoiesis and oxidative stress. Additionally, the potential therapeutic effects of Stevia rebaudiana Bertoni in mitigating these stress-induced alterations are explored. Immobilization stress was induced for 30 days, and its...
This study investigates the effects of X-radiation on ATPase activity and antioxidant enzyme activity, particularly enzymes involved in proline biosynthesis, in yeast C. guilliermondii NP-4. Moreover, the study examined the post-irradiation repair processes in these cells. Results showed that X-irradiation at a dose of 300 Gy led to an increase in...
Conventional treatment methods are not effective enough to fight the rapid increase in cancer cases. The interest is increasing in the investigation of herbal sources for the development of new anticancer therapeutics. This study aims to investigate the antitumor capacity of Hypericum alpestre (H. alpestre) extract in vitro and in vivo, either alon...
Conventional treatment methods are not effective enough to fight the rapid increase in cancer cases. The interest is increasing in the investigation of herbal sources for the development of new anticancer therapeutics. Particularly, much attention is given to finding combined phytochemical/chemotherapeutic treatment models to overcome drug resistan...
Background: Conventional treatment methods are not effective enough to fight the rapid increase in cancer cases. The interest is increasing in the investigation of herbal sources for the development of new anticancer therapeutics. Particularly, much attention is given to finding combined phytochemical/chemotherapeutic treatment models to overcome d...
This study aimed to investigate the effect of X-radiation on the ATPase activity and the activity of antioxidant enzymes, including enzymes of proline biosynthesis, in C. guilliermondii NP-4 yeast cells after X-irradiation and the post-irradiation repair of cells. It has been shown that the X-irradiation of yeasts C. guilliermondii NP-4 at a dose o...
The effect of extracts of Hypericum alpestre and Rumex obtusifolius L herbals on the amount of free proline and the activity of proline biosynthesis enzymes in various organs of the rat was studied. It was shown that the activity of proline biosynthesis enzymes under the influence of R. obtusifolius L. extracts decreased in the liver by 74.7%, in t...
Vibration pathology is in the second place among diseases connected to the profession. The vibration effect both on the protein fraction shifts and on the activities of I type arginase (Arg) IA and IB from white rat liver has been studied in the conditions of 5-, 10- and 15-day vibration state. In the initial state of vibration some decrease of Arg...
Experimental and theoretical articles• Հայաստանի կենսաբ. հանդես, 1-2 (72), 2020 RANA RIDIBUNDA ԳՈՐՏԻ ԼՅԱՐԴԻՑ ԱՆՋԱՏՎԱԾ ՈՐՈՇ ՍՊԻՏԱԿՈՒՑԱՅԻՆ ՖՐԱԿՑԻԱՆԵՐԻ ԴԵՐԸ ԱՊԱԱԿՏԻՎԱՑՎԱԾ ԱՐԳԻՆԱԶ I-Ի «ԻՆՔՆԱՀԱՎԱՔՄԱՆ» ԳՈՐԾԸՆԹԱՑՈՒՄ Է.Խ. ԲԱՐՍԵՂՅԱՆ, Հ.Մ. ԿԱՐԱՊԵՏՅԱՆ, Ա.Հ. ԹՌՉՈՒՆՅԱՆ ԵՊՀ, կենսաքիմիայի, մանրէաբանության և կենսատեխնոլոգիայի ամբիոն hkarapetyan@ysu.am Հետազոտվել ե...
The changes of antioxidant enzymes – catalase and peroxidase activity and lipid superoxide
oxidation processes in rabbit blood have been determined in conditions of immobilization stress long
duration. It was also studied stevia (Stevia rebaudiana Bertoni) effect on oxidant and antioxidant
systems. It was revealed that with stress effect duration l...