
Hasitha GajaweeraUniversity Hospital Southampton NHS Foundation Trust · Department of Paediatrics
Hasitha Gajaweera
MBBS DCH MD HERMES diploma in paediatric respiratory medicine
About
14
Publications
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Citations
Publications
Publications (14)
Introduction
Kaftrio (Elexacaftor-Tezacaftor-Ivacaftor) is a recently introduced CFTR modulator to treat people with Cystic fibrosis (CF) who have at least one copy of the F508del mutation. We have evaluated the wider efficacy of this treatment using the Cystic Fibrosis Questionnaire-Revised (CFQ-R), Warwick-Edinburgh Mental Wellbeing Score (WEMWBS...
Abstract
Objective
Severe paediatric obstructive sleep apnoea in typically developing children with adenotonsillar hypertrophy is primarily managed surgically. Non-emergency ENT surgery was paused early in the coronavirus disease 2019 pandemic and children were offered medical management for obstructive sleep apnoea.
Methods
A service evaluation w...
Paroxysmal cold hemoglobinuria (PCH) is a very rare subtype of autoimmune hemolytic anemia caused by the presence of cold-reacting autoantibodies in the blood and characterized by the sudden presence of hemoglobinuria, typically after exposure to cold temperatures. The acute onset PCH occurs following viral illnesses whilst the chronic form is seco...
Background
Sleep disordered breathing (SDB) is an umbrella term encompassing obstructive and central sleep apnoea. Overnight studies are used to confirm the diagnosis, however the minimum amount of artefact-free recording time (AFRT) required is yet to be determined in children.
Aim
To determine the impact of different lengths of AFRT on the diagn...
Background
Overnight studies are used to diagnose sleep disordered breathing (SDB), however the minimum artefact-free recording time (AFRT) has not been established in children.
Aim
To determine the impact of AFRT on SDB diagnoses.
Methods
Patients attended overnight cardiorespiratory polygraphy/polysomnography, alongside pulse oximetry sleep stu...
Introduction:
Asthma is a major childhood illness. Studies have shown associations between aeroallergen exposure and asthma globally
Objectives:
To evaluate the association between aeroallergen sensitivity and asthma control in children with asthma attending a specialist child care hospital and to compare these findings with a study from the same c...
Paroxysmal cold hemoglobinuria (PCH) is a very rare subtype of autoimmune hemolytic anemia caused by the presence of cold-reacting autoantibodies in the blood and characterized by the sudden presence of hemoglobinuria, typically after exposure to cold temperatures. The acute onset PCH occurs following viral illnesses whilst the chronic form is seco...
Background Central apnoea occurs in 1-5% of children. Important aetiologies include • Anatomical brain abnormalities-Arnold Chiari malformation and foramen magnum stenosis • Other conditions-brain tumours , Downs syndrome , intracranial pathology secondary to hypoxic insults etc.
Introduction:
Regional lymphadenopathy is a common clinical entity in children. It possesses a wide aetiological spectrum. Infection is the commonest cause while, reactive adenitis due to viral infections represents the majority. However, tuberculosis (TB) would be a leading cause which should be considered when response to conventional treatment i...
Introduction and Objectives
Asthma is a complex disease with multiple interacting factors determining individual phenotypes. We performed a service evaluation of children attending specialist paediatric respiratory clinics for their asthma at tertiary care hospital as part of routine follow up and whilst shielding according to NHS advice during the...