Hashim Talib Hashim

• Doctor of Medicine and Surgery (MD)
• Head of research department at University of Warith Al-Anbiyaa

Objectives To explore trial participants’ experience of long-term catheters (LTC), the acceptability of washout policies, their experience of the CATHETER II trial (a randomised controlled trial comparing the clinical effectiveness of various washout policies versus no washout policy in preventing catheter associated complications in adults living...

Background and Aims Systemic lupus erythematosus (SLE) is a recurrent and remitting autoimmune disease that affects many organ systems. It is more common in women of reproductive age, with a 9:1 female preponderance. Due to the lack of data from developing countries, our study aims to provide comprehensive insights into the drug history and SLE lab...

Rationale Congenital anomalies of the aortic arch encompass a range of malformations that may remain clinically silent or present with severe respiratory or esophageal symptoms. These anomalies are crucial to recognize due to their association with vascular rings, congenital heart disease, and chromosomal abnormalities, which have significant impli...

This systematic review and meta-analysis evaluated the efficacy and safety of Trandolapril, an ACE inhibitor, in patients with heart failure (HF) by analyzing data from eight randomized controlled trials involving 13,582 participants. A comprehensive literature search was conducted following PRISMA guidelines, and statistical analyses were performe...

Objective This study aimed to evaluate the reliability and validity of the Binge Eating Disorder Screener‐7 (BEDS‐7) across 42 countries and 26 languages, assessing its reliability and validity as a screening tool for binge‐eating disorder (BED) in diverse cultural contexts. Specifically, it sought to enhance early recognition of BED symptoms in pr...

Sexual assertiveness (SA) is an important concept in understanding sexual well-being and decision-making. However, psychometric evaluation of existing measures of SA in diverse populations is largely lacking, hindering cross-cultural and comparative studies. This study validated the short version of the Sexual Assertiveness Questionnaire (SAQ-9) an...

32 Background: Prostate cancer remains a leading cause of cancer-related morbidity and mortality among men worldwide. Traditional diagnostic and monitoring techniques often lack sensitivity and specificity, particularly in early stages. Liquid biopsies, which analyze circulating tumor cells (CTCs) and circulating tumor DNA (ctDNA) from blood sample...

768 Background: The gut microbiome has emerged as a critical factor influencing the efficacy and toxicity of cancer treatments. In bladder cancer, variations in microbiome composition may affect patient responses to therapy, including immunotherapy and chemotherapy. This meta-analysis aims to comprehensively evaluate the impact of gut microbiome co...

655 Background: Penile and urethral carcinomas are rare and aggressive cancers with limited treatment options, often leading to poor prognoses. Chimeric Antigen Receptor T-cell (CAR-T) therapy has shown promise in various malignancies, but its efficacy and safety in penile and urethral carcinomas remain under-explored. This meta-analysis aims to ev...

Objective: To determine the association between intracerebral hemorrhage mortality and statin therapy, aiming to provide effective methods to prevent intracerebral hemorrhage and reduce the mortality rate. Background: Intracerebral hemorrhage (ICH) poses significant challenges due to its high mortality and disability rates, especially among Asian p...

Background and aims: Despite a growing body of research on pornography use among women, there is a lack of understanding of the problematic versus non-problematic nature. The current study aimed to investigate the relationship between women’s motivations for pornography use and sexual wellbeing using a cross-sectional, self-report survey design amo...

Purpose Early detection of breast cancer is crucial for improving patient outcomes. With advancements in artificial intelligence (AI), there is growing interest in its potential to assist radiologists in interpreting mammograms for early cancer detection. AI algorithms offer the promise of increased accuracy and efficiency in identifying subtle sig...

Sexual satisfaction can be important for overall well-being and has been described as a sexual right. Individual and cultural factors, such as gender identity and sexual orientation, may influence the ways in which individuals describe, share, or experience their sexuality. The aims of the present study were to examine the factor structure of the f...

Background Prevention programs for dementia are gaining increasing attention as the global population ages. These initiatives aim to reduce the risk of developing dementia by promoting brain health and implementing lifestyle changes. Through strategies such as regular physical exercise, a balanced diet, cognitive stimulation, and managing chronic h...

Purpose: Early detection of breast cancer is crucial for improving patient outcomes. With advancements in artificial intelligence (AI), there is growing interest in its potential to assist radiologists in interpreting mammograms for early cancer detection. AI algorithms offer the promise of increased accuracy and efficiency in identifying subtle...

We present a case detailing the diagnostic challenges of a 23-year-old male presenting with a sudden severe headache, nausea, vomiting, and chest heaviness. Initial evaluation showed elevated blood pressure and respiratory rate. An emergency electrocardiogram (ECG) indicated ST-segment elevation myocardial infarction (STEMI), leading to immediate r...

Penetrating neck injury (PNI), involving disruption of the platysma muscle, accounts for 10% of trauma cases and poses significant morbidity and mortality risks. This case report details the management of a 45-year-old male who sustained a 270-degree circumferential neck incision from an industrial accident. The patient presented with a deep neck l...

Objectives Do weekly prophylactic saline or acidic catheter washouts in addition to standard long-term catheter (LTC) care improve the outcomes of adults with LTC compared with standard LTC care only. Design Three-arm superiority open-label randomised controlled trial. Setting UK community-based study. Participants 80 adults with LTC (any type/r...

Background: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease affecting multiple organs, while brucellosis is a zoonotic infection prevalent in endemic areas. Neurobrucellosis, a severe complication of brucellosis, can mimic or coexist with autoimmune conditions like SLE, complicating diagnosis and treatment. This case report highl...

Infertility was reported in approximately 15% of all heterozygous couples, with the male factor accounting for nearly half of the cases. This typically occurs due to low sperm production, sperm dysfunction, and sperm delivery obstruction. In this randomized controlled single-blind clinical trial, 90 infertile male subjects diagnosed with oligosperm...

Back pain Tension pneumothorax Nonsmoker a b s t r a c t Spontaneous pneumothorax usually presents with sudden chest pain and dyspnea as cardinal symptoms, but its diagnosis may be challenging with atypical presentation. We describe here the case of an unusual presentation of spontaneous pneumothorax in a 20-year-old male nonsmoker with no past med...

Sexual desire is a complex construct with important implications for sexual functioning and well-being. In this research, we translated the Sexual Desire Inventory (SDI-2), a widely used scale for assessing sexual (desire), into 25 languages from English and used data from the International Sex Survey (ISS) to (a) investigate its psychometric prope...

Background Pre-diabetes, characterized by elevated glycemic indices, poses a high risk of diabetes development, and is increasingly linked to non-specific low back pain. While mechanisms remain incompletely understood, metabolic, inflammatory, and neurological factors are implicated. Dietary interventions, including low-glycemic and anti-inflammato...

Background: In the management of acute myocardial infarction (AMI) following percutaneous coronary intervention (PCI), dual antiplatelet therapy (DAPT) plays a crucial role in preventing recurrent ischemic events. Recent studies have explored the feasibility and safety of de-escalating DAPT from ticagrelor to clopidogrel. Methods: We conducted a sy...

Background: Folic acid, a B vitamin, is essential for DNA synthesis and repair, and its role in reducing homocysteine levels has been linked to cardiovascular health. Elevated homocysteine is a risk factor for cardiovascular diseases, including acute myocardial infarction (MI) and coronary artery disease (CAD). Despite evidence suggesting that foli...

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is a leading infectious disease with varied manifestations. We report a rare presentation of gastric TB in a 50-year-old immunocompetent woman from the Middle East with no prior medical history. The patient presented with persistent epigastric pain, weight loss, nausea, and vomiting over a 2-...

Virtual reality (VR) technology is perfect with the help of pc, laptop and virtual world integration awareness. The current analysis argues on the application of VR technology inclinic, especially in medical training, panic controlling, any phobia like eating, flying, height phobia etc. therapeutic cure of mental disorder. This research gives a sho...

Introduction The Arizona Sexual Experiences Scale (ASEX) is a brief questionnaire that evaluates five major aspects of sexual function: sex drive, arousal, erectile function/vaginal lubrication, ability to reach orgasm, and satisfaction with orgasm. An advantage of the ASEX is its simplicity and brevity (five items), making it suitable for the scre...

Objectives Type 2 diabetes mellitus (T2DM) is a persistent metabolic illness causing elevated glucose levels due to insulin resistance. Social media has been found to positively impact diabetes management by boosting motivation, adherence, emotional support, and sharing evidence-based information, thereby enhancing patients’ glycemic control effort...

Background: According to The Centers for Disease Control and Prevention (CDC) 2019, around 32,000 deaths in addition 2.8 million infections occur annually in the US because of antibiotic-resistant bacteria. Objectives: To determine the prevalence and study pattern of antibiotic use and resistance among Iraqi patients. Methodology: We carried out a...

Cabazitaxel, a second-generation taxane chemotherapy agent, has demonstrated efficacy in treating metastatic castration-resistant prostate cancer (mCRPC) in patients who have previously received docetaxel-based therapy. By targeting microtubule dynamics, cabazitaxel inhibits cancer cell division and induces apoptosis, thereby extending survival and...

Objectives An abscess is a localized collection of pus contained within a fibrous capsule. In this study, we aimed to determine the demographic pattern, common anatomical sites, risk factors, and the microbial profile of abscesses in different body sites among children. Methods We conducted a prospective study in our pediatric surgical department...

Background and Aim The role of Resmetirom in non‐alcoholic steatohepatitis (NASH) represents a promising therapeutic approach in addressing the growing global burden of liver disease. With NASH emerging as a leading cause of liver‐related morbidity and mortality worldwide, there is an urgent need for effective treatments. Resmetirom, a selective th...

Lower back pain with radiculopathy is a common clinical presentation caused by several conditions, some of which are rare pathologies that could have been overlooked during an initial assessment. This case report presents a patient complaining of chronic lower back pain and radiculopathy who finally received a diagnosis for his presacral ganglioneu...

Pulmonary hydatidosis Ovarian drilling Postoperative complications Parasitic infection Thoracic surgery Echinococcosis a b s t r a c t Echinococcus granulosus is the parasite that causes hydatid disease. The liver is the most often affected organ, followed by the lungs and other organs. We present the case of a 24-year-old woman who had no notable...

Complications Case report a b s t r a c t An uncommon but potentially life-threatening complication of spinal surgery is bacterial meningitis, To the best of our knowledge, all of the documented cases have developed following open procedures, likely due to the increased potential for cerebrospinal fluid exposure and dural injury associated with the...

Autoimmune Rheumatoid Thrombocytopenia Immunosuppressive agents a b s t r a c t Evans syndrome is a rare autoimmune disorder characterized by autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP), often linked with systemic lupus ery-thematosus (SLE). We present a case of a 25-year-old female with a history of rheumatoid arthritis (R...

Early renal dysfunction Asphyxiating thoracic dystrophy Neonatal respiratory distress Skeletal dysplasia a b s t r a c t Jeune syndrome, a rare autosomal recessive disorder, is characterized by skeletal abnormalities , particularly a narrow, bell-shaped chest, leading to severe respiratory distress in newborns. This case report details a full-term...

Ichthyosis Prematurity Syndrome (IPS) is a rare autosomal recessive disorder characterized by premature birth, respiratory distress, and distinctive skin abnormalities. Infants with IPS typically present between 30 and 34 weeks of gestation with a thick, caseous, desquamating epidermis resembling vernix caseosa. We report a case of a female neonate...

Small cell carcinoma of pancreas Neuroendocrine differentiation Thyroid transcription factor-1 Metastatic disease Tumor markers a b s t r a c t Small cell carcinomas are very aggressive malignancies that are most often linked with lung cancer, although they may also develop in the pancreas, colon, rectum, skin, and cervix. SCC of the pancreas accou...

Alkaptonuria is an inborn error of metabolism inherited as an autosomal recessive disorder due to a mutation in the homogentisic acid dioxygenase gene. It occurs rarely (global prevalence of alkaptonuria is 1 in 100,000 to 250,000), and mainly affects the joints and connective tissue of the body due to deposition of homogentisic acid giving affecte...

Background Metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) are prevalent conditions linked to obesity and metabolic disturbances, with potential complications such as cirrhosis and cardiovascular risks. This systematic review and meta-analysis aimed to evaluate the efficac...

Background Cancer is a group of diseases that results from the growth of cells in an uncontrolled way, and in addition spreading of abnormal cells. At the molecular level, Alterations of oncogenes, tumor-suppresser genes, and microRNA genes cause cancer. These alterations of genes usually occur at the somatic level, if they occur as germline mutati...

Background Pancreatic cancer is one of the main causes of cancer-related deaths, especially pancreatic ductal adenocarcinoma and it’s characterized by a poor prognosis. The KRAS gene mutation is prevalent in about 85% of pancreatic cancer cases which is a significant factor in the pathogenesis and development of pancreatic cancer, impacting cellula...

Pulmonary artery aneurysm (PAA) in Behcet’s disease is a rare yet potentially life-threatening manifestation, often presenting as haemoptysis. We present a case report of a 33-year-old male with recurrent haemoptysis and a history of oral and genital ulcers, diagnosed with Behcet’s disease complicated by PAA. Diagnostic workup, including imaging an...

Objective to evaluate efficacy of dupilumab in the treatment of CRSwNP. Background Chronic rhinosinusitis with nasal polyps (CRSwNP) represents an inflammation of the nasal and sinus mucosa, it is not uncommon disease. Patient with CRSwNP is presented nasal obstruction, facial pain, recurrent sinus infections, and anosmia. Dupilumab is an inhibito...

Key Clinical Message Early recognition and management of seronegative celiac disease, even in the absence of typical serological markers, can prevent complications and ensure better health outcomes in pediatric patients. Consideration of a gluten‐free diet in similar cases can lead to significant clinical improvement. Abstract Celiac disease, char...

Livedoid vasculopathy (LV) is a chronic, recurrent thrombotic vasculopathy characterized by painful ulcerations on the lower extremities, which heal slowly and leave atrophic white scars known as “atrophie blanche.” This report presents the case of a 31-year-old woman with a 4-year history of recurrent painful ulcerations on her legs and feet. A sk...

The UPPS-P Impulsive Behavior Model and the various psychometric instruments developed and validated based on this model are well established in clinical and research settings. However, evidence regarding the psychometric validity, reliability, and equivalence across multiple countries of residence, languages, or gender identities, including gender...

This study examines the contraindications of gabapentin and Nucleo C.M.P Forte in metformin-controlled diabetic patients, focusing on their potential to induce hyperglycemia. A case report of a 65-year-old woman with type II diabetes is presented, demonstrating elevated blood glucose levels following the initiation of gabapentin and Nucleo C.M.P Fo...

Here, we report a rare case of a 22-year-old female presenting with recurrent chest pain mimicking inferior ST-elevation myocardial infarction (STEMI) but ultimately attributed to an aortic aneurysm. Despite facing initial challenges in diagnosis, such as normal troponin levels and temporary electrocardiogram (ECG) changes, advanced imaging showed...

Introduction Remote ischemic preconditioning (RIPC) is a phenomenon in which the induction of shortened periods of ischemia prior to surgical procedures within a distant tissue preserves other tissues or organs of concern, such as the liver or kidney in transplant surgery, in the event of prolonged ischemic insults. We aim to evaluate the effective...

Motivations for pornography use may vary across gender identities, sexual orientations, and geographical regions, warranting examination to promote individual and public health. The aims of this study were to validate the Pornography Use Motivations Scale (PUMS) in a diverse, multicultural sample, and develop a short form (PUMS-8) that can assess a...

Benign prostatic hyperplasia (BPH), often known as prostate gland enlargement, is a common disorder in elderly men. The nine sweeps or Istibra, a traditional Islamic habit, has been hypothesized to decrease the risk of prostate diseases. This study aims to investigate the potential preventive effects of Istibra on prostate cancer and BPH among indi...

We present the case of a 27-year-old pregnant woman, newly diagnosed with Systemic Lupus Erythematosus (SLE) during pregnancy. The patient delivered a newborn at 38 weeks gestation, who, on the first day of life, manifested complete heart block. This case underscores the clinical challenges associated with neonatal lupus, emphasizing the need for c...

Key Clinical Message Timely recognition of atypical Takayasu arteritis is crucial. Unusual presentations, such as pericardial effusion, can complicate diagnosis. CT angiogram aids in precise diagnosis, guiding targeted immunosuppressive therapy. Multidisciplinary collaboration is vital for comprehensive management, improving patient outcomes in thi...

We present a case of a twenty-month-old male with DS who experienced a range of dysmorphic and clinical features with the involvement of multiple systems. These features include skin hyperpigmentation, hypertrichosis, distinct facial features, abdominal distension, and microcephaly, with the involvement of the endocrine, renal, respiratory, and car...

Background and Aims The present study aims to shed light on the knowledge, attitude, and practice of breast self‐examination with breast cancer (BC) among female patients in the oncology department of Baghdad Medical City. Methods This cross‐sectional study involved 100 female participants at the Oncology Teaching Hospital in Baghdad Medical City...

This case report outlines the management of a 43-year-old male with no past medical history presenting with inferior ST-segment elevation myocardial infarction and a positive “Dead Man Sign.” Prompt administration of antiplatelet therapy and emergent percutaneous coronary intervention led to successful revascularization of the occluded right corona...

Schizencephaly is defined as “Abnormal slits or clefts in the brain hemispheres”, these slits cause brain development to be abnormal and they may be caused by genetic causes or multifactorial causes. This malformation has many complications like seizures, abnormal development, mental retardation and paralysis. It may be associated with other malfor...

Congenital brain malformations are presented at birth as a result of abnormalities or defects in fetal development during the embryological stages. The brain is the main center that controls almost all of the body, so, any defect involved will have wide consequences in the short and long term unless they are treated. Almost all congenital brain mal...

When the posterior fossa of the skull fails to develop normally during prenatal development, this condition is known as a posterior fossa malformation. Classification of posterior fossa malformation can either be depending on the size of the posterior fossa and the diameter of the rhombencephalon vesicles and also on how the developed form the rhom...

Introduction Donohue syndrome (DS), also referred to as leprechaunism, is a remarkably uncommon autosomal recessive disorder that primarily affects the endocrine system. Its incidence rate is exceedingly low, with only 1 case reported per 4 million live births. The syndrome is distinguished by a series of characteristic clinical features. Case pre...

We present a case of a twenty-month-old male with DS who experienced a range of dysmorphic and clinical features with the involvement of multiple systems. These features include skin hyperpigmentation, hypertrichosis, distinct facial features, abdominal distension, and microcephaly, with the involvement of the endocrine, renal, respiratory, and car...

Background: Acute decompensated heart failure (ADHF) presents a significant global health challenge, with high morbidity, mortality, and healthcare costs. The current therapeutic options for ADHF are limited. Ivabradine, a selective inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, has emerged as a potential therapy...

Key clinical message Early identification of rib fractures, even in young patients without chronic diseases, is essential. Prompt diagnosis facilitates appropriate management, aiding in pain control and addressing underlying causes such as persistent coughing. Additionally, vigilance for complications such as pneumothorax and rib displacement is cr...

Key Clinical Message Ibuprofen single dose may rarely induce Stevens–Johnson Syndrome, emphasizing the vital need for heightened vigilance in healthcare and public awareness for safer medication practices. Abstract Stevens–Johnson Syndrome (SJS) is a severe and potentially life‐threatening skin disorder associated with certain medications, includi...

Background. Depression and anxiety are among the most prevalent mental health issues experienced worldwide. However, whereas cross-cultural studies utilize psychometrically valid and reliable scales, fewer can meaningfully compare these conditions across different groups. To address this gap, the current study aimed to psychometrically assess the B...

Objectives: This study aimed to examine the psychometric properties of the P4 suicide screener in a multinational sample. The primary goal was to evaluate the reliability and validity of the scale and investigate its convergent validity by analyzing its correlation with depression, anxiety, and substance use. Study design: The study design is a cro...

Background The three-item Sexual Distress Scale (SDS-3) has been frequently used to assess distress related to sexuality in public health surveys and research on sexual wellbeing. However, its psychometric properties and measurement invariance across cultural, gender and sexual subgroups have not yet been examined. This multinational study aimed to...

Background The establishment of psychiatric services in general hospitals has been driven by various factors, including the prioritization of communicable and non-communicable diseases, the de-institutionalization movement in mental health care, and the geographic and sociocultural barriers to accessing specialized psychiatric services. In Iraq, th...