Harry Freitag Luglio

Harry Freitag Luglio
Universitas Gadjah Mada | UGM · Department of Health Nutrition

MSc, RD

About

49
Publications
11,276
Reads
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194
Citations
Introduction
I am a lecturer and researcher from UGM, Indonesia with interest in molecular nutrition especially in obesity, immunology and nutrient metabolism. Currently seeking for a challenging Ph.D position in the field. Education: - Undergraduate School of Nutrition, UGM - Dietetic Internship Program, UGM - Musketeers Course on Immunology, UGM - Master of Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University
Additional affiliations
February 2015 - March 2015
KU Leuven
Position
  • Researcher
November 2012 - July 2013
Maastricht University
Position
  • Intern
February 2012 - July 2013
Maastricht University
Position
  • Intern
Education
September 2011 - September 2013
Maastricht University
Field of study
  • Molecular Life Sciences
September 2009 - May 2010
Department of Histology and Cell Biology, Faculty of Medicine, Gadjah Mada University
Field of study
  • Musketeers Course of Immunology
September 2008 - August 2009
Universitas Gadjah Mada
Field of study
  • Dietetic

Publications

Publications (49)
Article
Full-text available
Obesity has been linked to high dietary intake and low physical activity. Studies showed that those factors were not only regulated by environment but also by genetic. However, the relationship is less been understood in obese children and adolescents. The objective of this study was to examine the role of SNPs in GHSR rs292216 and rs509035 on diet...
Article
Full-text available
The ability of obese people to reduce weight in the same treatment varied. Genetic make up as well as the behavioral changes are important for the successfulness of the program. One of the most proposed genetic variations that have been reported in many intervention studies was genes that control lipolysis process. This review summarizes studies th...
Article
Background and Aims Obesity is associated with increased inflammation leading to a higher risk for non-communicable diseases. There was a controversy about whether exercise has a better influence on reducing inflammation during a lifestyle modification program among individuals with obesity. The objective of this study was to evaluate whether exerc...
Article
BACKGROUND Poor sleep duration and quality were previously reported to increase the risk of obesity. This study was aimed to evaluate the impact of sleep quality and duration on leptin, appetite, and adiposity in Indonesian adults. METHODS This cross-sectional study recruited adults in Yogyakarta, Indonesia, in 2016. Sleep quality was assessed usi...
Article
Behavioural modification through physical activity and dietary counselling has been shown to have beneficial effects on pregnant women with overweight/obesity. Whether exercise alone with supervision (ie, supervised exercise) may also benefit for pregnant women with overweight/obesity is still unknown. This systematic review and meta‐analysis aimed...
Article
Background/Introduction The uncoupling protein 2 (UCP2) is recently being recognized as an important molecule involved in the development of cardiovascular diseases such as vascular dysfunction, atherosclerosis, and hypertension. It was previously reported that the UPC2 –866 G/A gene variation was associated with obesity and hypertension. Purpose...
Article
Full-text available
COVID-19 is a disease that has affected millions of people worldwide and made a significant impact on health, social life, and economy. One of the strategies to prevent the spread of this virus is through self-isolation. Although this strategy is efficient to prevent a drastic spread of the disease, there are some consequences related to this measu...
Article
This study aimed to investigate an interaction between energy intake, physical activity, and UCP2 gene variation on weight gain and adiposity changes in Indonesian adults. This is a prospective cohort study conducted in 323 healthy adults living in the city of Yogyakarta, Indonesia. Energy intake, physical activity, body weight, body mass index (BM...
Article
Background Obesity has been associated with genetic and environmental factors. Although carbohydrate intake was previously shown to be associated with a high risk of obesity and insulin resistance, some studies reported that genetic factors also have a role in this association. KCNJ11 is a gene involved in protein K-ATP channels of pancreatic beta...
Article
This study aimed to explore the effect of Zumba training on body composition and its compensatory effect on dietary intake and sleep in sedentary overweight women. This was an experimental study with crossover design conducted in 34 subjects. We showed that Zumba training was associated with the reduction of body fat (P = .023) but not body weight...
Article
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Obesity among adolescents is a new nutritional problem in Indonesia. This is not only associated with increased risk for obesity in later life but also increased the risk for cardiovascular diseases, type 2 diabetes mellitus, hypertension, and other non-communicable diseases. Therefore an effective and integrated obesity prevention program is highl...
Article
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Introduction World Health Organization (WHO) estimates the prevalence of people with diabetes increased from 4.1% (1980) to 8.6% (2014) in the Southeast Asia region. A few studies have examined impaired fasting glucose (IFG) as the main factor precedes diabetes while nutritional status, imbalanced diet, and physical activity as risk factors of IFG....
Article
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Background: Appetite and dietary intake have been associated with obesity and successfulness of weight loss in obese individuals. Glucagon-like peptide 1 is a gut-derived neuropeptide that is produced as a response to dietary intake and associated with appetite. It has been investigated that prebiotic can induce GLP-1 production in animal models an...
Article
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It was previously reported that dietary intake is an important trigger for systemic inflammation and one of the lifestyle factors for the development of cardiovascular diseases. The aim of this study was to evaluate the association between Dietary Inflammatory Index (DII) score and body weight, blood pressure, lipid profile and leptin in an Indones...
Article
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Background Coffee is suggested as an alternative option for weight loss but the relationship between coffee consumption and adiposity in population-based studies is still controversial. Therefore, this study was aimed at evaluating the relationship between coffee intake and adiposity in adults and to test whether uncoupling protein 2 (UCP2) gene va...
Article
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Objectives: FTO rs9939609 variant has been shown to be associated with insulin resistance in Caucasian children. However, studies in Asia show inconsistent findings. We investigated the association between FTO rs9939609 polymorphisms and insulin resistance in obese female adolescents in Indonesia, a genetically distinct group within Asia. Results...
Article
Purpose Stunting and being underweight in children are major nutritional problems especially in developing countries. The purpose of this study is to evaluate the effect of egg supplementation on a vitamin and mineral fortification program for growth, cognitive development and hemoglobin in underweight and stunted children. Design/methodology/app...
Article
BACKGROUND: Ramadan fasting has been associated with a significant body weight, fat mass andwaist-hip circumference reduction. However, this is mostly followed by weight regain in 2 weeks after the fasting is stopped. Currently there is no explanation on how this rebound phenomena occurred. OBJECTIVE: The aim of this study was to examine the role o...
Article
Stunting or short stature in children is a significant nutritional problem in developing and underdeveloped countries. Stunting during childhood might affect brain development and impair development cognitive function. Additionally, this condition associated with the increased risk for obesity during adulthood. Several studies have shown that the i...
Article
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Background Transcription factor 7-like 2 (TCF7L2) and potassium voltage-gated channel subfamily j member 11 (KCNJ11) gene polymorphisms have been associated with type 2 diabetes mellitus (T2DM) via regulation of insulin production. Ingested nutrients induce glucagon-like peptide-1 (GLP-1), which in turn induces insulin secretion.Objective To evalua...
Article
Background Transcription factor 7-like 2 (TCF7L2) and potassium voltage-gated channel subfamily j member 11 (KCNJ11) gene polymorphisms have been associated with type 2 diabetes mellitus (T2DM) via regulation of insulin production. Ingested nutrients induce glucagon-like peptide-1 (GLP-1), which in turn induces insulin secretion. Objective To eval...
Article
Full-text available
Weight regain after successful weight loss is a big problem in obesity management. This study aimed to investigate whether weight regain after a weight loss period is correlated with the macronutrient composition and/or the inflammatory index of the diet during that period. Sixty one overweight and obese adults participated in this experimental stu...
Article
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Background: Obesity has been associated with leptin resistance and this might be caused by genetic factors. The aim of this study was to investigate the gene-lifestyle interaction between -866G/A UCP2 (uncoupling protein 2) gene polymorphism, dietary intake and leptin in a population based study. Methods: This is a cross sectional study conducte...
Article
Background: Overfatness (overweight and obesity) is associated with an increased risk of cardiovascular disease, including elevated blood pressure, dyslipidaemia, and insulin resistance. Chronic inflammation may play a role in mediating these associations. Objective: To investigate the association between plasma tumour necrosis factor-α and risk...
Article
The aim of this study was to develop a new exercise regime with a mixture of aerobic and strength training combined with a low-calorie diet (1200 kcal/d) and to evaluate its health benefit in overweight/obese individuals. In 8 weeks of study, participants were divided into 2 groups: a lowcalorie diet alone and a low-calorie diet with exercise regim...
Article
Full-text available
Background: Socioeconomic status (SES) has an important role in defining trend of obesity and it is believed that rich people of poor countries who live in urban areas show high rate of obesity. However, there is a controversy regarding the role of socioeconomic factors on overweight and obesity of people living in rural areas. Objectives: The aim...
Article
Background and objectives: Pro-inflammatory cytokines interleukin 17A (IL-17), leptin, and adiponectin have been associated with obesity and insulin resistance. Moreover, differences in sex and ethnicity as well as plasma concentration of adipocytokines and cytokines have been associated with the risk of insulin resistance. This study was conducte...
Article
Background: The iodine deficiency disorder (IDD) has become a worldwide problem because the prevalence is increasing in the recent decades. IDD occurs not only in developing countries, but also in developed countries. This study analyzed the effect of various combinations of egg, iron, iodine supplementation on nutritional status, thyroid hormones...
Article
BACKGROUND: Obesity is linked to high dietary intake and low physical activity. Studies showed that those factors were not only regulated by environment but also regulated by genetic variations. However, the relationship has less been understood in obese children and adolescents. OBJECTIVE: The objective of this study was to examine the role of SNP...
Article
Purpose This study aims to examine the effect of lesser yam-based cookies on glucagon-like peptide-1 (GLP-1), blood glucose and lipid profile in overweight and obese individuals. Design/methodology/approach This was an experimental study on overweight or obese adults aged 21-50 years old. The intervention was done by giving 87g of cookies made wit...
Article
Full-text available
Obesity in adolescents has been associated with increased cardiovascular risk factors such as dyslipidemia and insulin resistance. Several factors have been proposed to be associated with cardiovascular risk factors in adolescents including dietary habit, physical activity and genetic. This study was aimed to evaluate the interaction between geneti...
Article
Full-text available
Modulation of fat metabolism is an important component of the etiology of obesity as well as individual response to weight loss program. The influence of lipolysis process had receives many attentions in recent decades. Compared to that, fatty acid oxidation which occurred after lipolysis seems to be less exposed. There are limited publications on...
Article
Obesity is a worldwide problem that adversely affects human health. Genetic factors have been suggested to play role in the development of obesity. SNPs on proteins involved in de novo lipogenesis had been proposed to affect individual susceptibility for obesogenic environment. De novo lipogenesis is the process of converting carbohydrate absorbed...
Article
The low cytochrome c oxidase (COX)-1 activity was associated with reduction of adenosin triphosphate (ATP) production in diabetes mellitus (DM) individuals. Interestingly, the secondary metabolite of Dioscorea esculenta (lesser yam) fermentation in gut can increase ATP production. OBJECTIVES:The aim of this study was to evaluate the effect of Lesse...
Article
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Tattermusch et al (2012) identified an IFN-inducible gene signature in whole blood of HAM/TSP patients, with a strong myeloid component, while abortive HTLV-1 infection induces monocyte apoptosis (Sze et al. 2013). We previously demonstrated that B cell CD80 expression correlates to disease severity in HAM/TSP (Menezes et al 2014), whereas B cell C...
Article
Full-text available
Estrogen has an important role in regulation of fat metabolism. Recent studies indicated that this process occurred due to inhibition of lipolysis by external estrogen administration. However, there was limited information regarding molecular process responsible for this phenomenon. This paper was aimed to present a brief update on recent studies e...
Article
Full-text available
Scope: FTO is now confirmed as the gene responsible for obesity but epidemiological studies showed various results based on different locations in the gene and in which ethnic group the polymorphism was found. The objective of this meta analysis was to contrast reports on FTO and obesity association among Asian and Caucasian ancestries. Methods and...
Article
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Results Among the 78 obese adolescent girls, 44 (56.4%) were at insulin resistance state. All subjects had Pro12Pro PPARg2 and del/del UCP2 genotype. Compared to the other polymorphisms analyzed in this study, the AA genotype and the A allele of UCP2-866 G/A polymorphism was found to have highest association with insulin resistance state (OR: 2.75;...
Article
Full-text available
Background A previous study on obese female adolescents inYogyakarta done in the year 2007 suggests that genetic factorsmight influence insulin resistance. One genetic factor that hasbeen associated \\lith insulin resistance in other populations isthe 􀁐55C;T polymorphism in the uncoupling protein 3 (UCP3)gene.Objective To investigate an association...
Article
Full-text available
Background A previous study on obese female adolescents in Yogyakarta done in the year 2007 suggests that genetic factors might influence insulin resistance. One genetic factor that has been associated with insulin resistance in other populations is the -55C/T polymorphism in the uncoupling protein 3 (UCP3) gene. Objective To investigate an associ...
Article
Full-text available
Introduction: Pregnant women are encouraged to comply with dietary recommendations to meet their own nutritional needs as well as their child. Deficiency of certain nutrients may lead to morbidity of both the mother and child. In this review, information on nutrients intake of pregnant women from studies conducted in Indonesia will be analysed. M...
Article
Full-text available
Background The worldwide increase in the prevalence of cardiovascular diseases in adulthood is related to obesity in children and adolescents. Insulin resistance and hyperinsulinemia observed in obese individuals are the precursors of cardiovascular action on insulin receptors, is proposed to be an important factor in preventing insulin resistance....

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