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Citations since 2017
4 Research Items
June 2021 - present
- Research Assistant
- Teaching undergraduate medicinal chemistry courses and Drug design courses
December 2014 - May 2021
- Teaching undergraduate medicinal chemistry courses and Drug design courses Studying general and special master courses Synthesis of novel compounds targeting CDK2 as potential anticancer agents
The structure-based design of some CDK2 inhibitors with a 3-(benzylidene)indolin-2-one scaffold as potential anticancer agents was realized. Target compounds were obtained as E/Z mixtures and were resolved to corresponding E- and Z-diastereomers. In silico studies using MOE 2019.01 software revealed better docking on the targeted enzyme for the Z-d...
Novel pyrrolo [2,3-b] pyrrole derivatives were synthesized and their hypolipidemic activity was assessed in hyperlipidemic rats. The chemical structures of the new derivatives were confirmed through spectral analysis. Compounds 5 and 6 were revealed to be the most effective hypolipidemic agents, with considerable hypocholesterolemic and hypotriglyc...
3-Arylidene-2-oxo-indoline derivatives are at the heart of a wide range of clinically, medicinally and biologically important compounds among the 2-oxo-indolines. A number of 3-arylidene-2-oxo-indolines have been approved for clinical application. Accordingly, the current work describes the structural based design of 3-arylidene-2-oxindole derivati...
I just received this email from Peer Review Department from "Insights in Biology and Medicine" Journal.
I think that this journal is not indexed.
Here is the email:
Dear Dr. Hany Mansour,
In the view of your eminence in the field, we kindly request you to review a manuscript from the Insights in Biology and Medicine.
This is to bring to your kind notice that we have received a manuscript entitled "Dead Sea Salt Solution: composition, lack of cytotoxicity and in vitro efficacy against oral leukotoxins, endotoxins, and glucansucrase"
We believe that your expertise and experience in the subject matter will certainly help in enhancing the quality of the manuscript.
We request you to accept this manuscript for review purpose and send the comments in the stipulated date.
Please find the attachments of the manuscript and Evaluation form.
Your support will be highly appreciated in publishing the research and development works in Open Access.
What is the most appropriate system that simulates the physiological system (pH 7.4) for studying E/Z isomerization (inversion) of small organic molecules? How to prepare it?