Hannes Hauswedell

Hannes Hauswedell
deCODE genetics, Inc. · Statistics department

Dr. rer. nat. / PhD Bioinformatics


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Additional affiliations
January 2013 - present
Freie Universität Berlin
  • PhD Student


Publications (19)
The search module offers data structures and algorithms for efficiently finding exact and approximate matches between the so-called query sequences and a text (also called subject sequence(s) or the reference). Query and subject may each be a single sequence or a collection of sequences, and typically the total subject size is much larger than the...
Full-text available
We describe the analysis of whole genome sequencing (WGS) of 150,119 individuals from the UK biobank (UKB). This yielded a set of high quality variants, including 585,040,410 SNPs, representing 7.0% of all possible human SNPs, and 58,707,036 indels. The large set of variants allows us to characterize selection based on sequence variation within a p...
Full-text available
This thesis introduces SeqAn3, a new software library built with Modern C++ to solve problems from the domain of sequence analysis in bioinformatics. It discusses previous versions of the library in detail and explains the importance of highly performing programming languages like C++. Complexity in the design of the library and of the programming...
Background: The use of novel algorithmic techniques is pivotal to many important problems in life science. For example the sequencing of the human genome Venter et al. (2001) would not have been possible without advanced assembly algorithms and the development of practical BWT based read mappers have been instrumental for NGS analysis. However, ow...
Full-text available
Motivation: Next-generation sequencing technologies produce unprecedented amounts of data, leading to completely new research fields. One of these is metagenomics, the study of large-size DNA samples containing a multitude of diverse organisms. A key problem in metagenomics is to functionally and taxonomically classify the sequenced DNA, to which e...


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