Hanie Edalati

• Doctor of Philosophy
• Senior Researcher at Canada's Drug Agency

Background Given the close relationship that can exist between substance use health and mental health (SUHMH) concerns, the need for more integrated services and support has been identified. However, research on the effective integration of SUHMH services and their impact on outcomes of individuals accessing them remains limited. In particular, the...

Objective To quantify and communicate risk equivalencies for alcohol-and tobacco-attributable mortality by comparing per standard drinks consumed to per number of cigarettes smoked in Canada. Methods Alcohol-and tobacco-attributable premature deaths (≤75 years of age) and years of life lost (YLL) were estimated using a lifetime risk modeling appro...

Aims: This study aimed to systematically review the literature on neuroanatomical predictors of future problematic drinking in adolescents. Methods: Using PRISMA guidelines, a systematic review was conducted to evaluate neuroanatomical predictors of problematic alcohol consumption in adolescents. EMBASE, MEDLINE, and PsycINFO databases were sear...

Alcohol use is causally linked to the development of and mortality from numerous diseases. The aim of this study is to provide an update to a previous systematic review of meta‐analyses that quantify the sex‐specific dose–response risk relationships between chronic alcohol use and disease occurrence and/or mortality. An updated systematic search of...

Aims This study aimed to systematically review the literature on neuroanatomical predictors of future problematic drinking in adolescents. Methods Using PRISMA guidelines, a systematic review was conducted to evaluate neuroanatomical predictors of problematic drinking in adolescents. Embase, MEDLINE, and PsycINFO databases were searched from incep...

Background Peer victimization (PV) is associated with alterations in neural responses in regions subserving emotional regulatory processes and with increased risk of psychopathology during adolescence. The present study examined the longitudinal mediating effects of resting-state functional connectivity (rsFC) between adolescent PV and subsequent i...

Background Adverse childhood experiences (ACEs) are strong risk factors for homelessness and poor health and functioning. We aimed to evaluate the lifetime prevalence of ACEs and their associations with health-related and functioning-related outcomes among homeless adults. Methods In this systematic review and meta-analysis, we searched from datab...

The externalizing psychopathological dimension is associated with alterations in adolescents’ functional brain connectivity. The current study aims to identify the functional correlates of the unique variability in conduct problems within the context of the broad externalizing dimension. The broad externalizing dimension and unique variability in c...

Exposure to childhood maltreatment and trauma has a strong relationship with onset and development of substance use disorders. The purpose of this chapter is to review important models and mechanisms that explain pathways from childhood trauma to substance misuse and dependence. This chapter integrates findings from several cross-sectional and long...

Review questions: * Are there any associations between alcohol consumption and changes in the neurobiology of adolescents? * Which structural and functional in vivo neuroimaging techniques can be used to determine these associations?

Objectives Exposure to adverse childhood experiences (ACEs) is associated with increased risk of criminal justice involvement and repeated victimization among homeless individuals. This study aimed to (1) examine whether the relationship between cumulative ACE score and odds of experiencing criminal justice involvement and victimization remains sig...

Background A range of school‐based prevention programs has been developed and used to prevent, delay, or reduce alcohol use among adolescents. Most of these programs have been evaluated at the community‐level impact. However, the effect of contextual risk factors has rarely been considered in the evaluation of these programs. The aim of this study...

Perceived stress plays an important role in the development and course of psychiatric disorders and early dropout from treatment. This study examined the effect of different types of childhood maltreatment on the current perceived stress level of patients with concurrent substance use and psychiatric disorders. One hundred patients (25% females) we...

Several school-based prevention programmes have been developed and used to prevent, delay, or reduce substance misuse, and related problems among community samples of adolescents. However, findings indicate that many of these interventions are associated with null, small, or mixed effects in reducing adolescent substance misuse, in particular for t...

Relationship between poor inhibitory control and adolescent interpersonal difficulties is well-documented. However, the way in which an emotionally neutral cognitive process (i.e., response inhibition) can lead to interpersonal difficulties is less clear. The current study is based on multimodal longitudinal data from 3,826 adolescents followed ove...

Adolescents involved with the child welfare system are at a high risk of early initiation of substance use and development of substance use disorders. However, there is an enormous gap between the needs and availability of the intervention programmes for prevention and treatment of substance use problems in at-risk adolescents involved in the child...

Adolescence is a transitional period of development characterized by critical changes in physical, neural, cognitive, affective, and social functions. Studies investigating the underlying mechanisms of substance use at levels of self-report, brain response, and behavioral data are generally consistent with suggestions from dual-process model that d...

Objective: Exposure to adverse childhood experiences (ACEs) is highly prevalent among homeless individuals and is associated with negative consequences during homelessness. This study examined the effect of ACEs on the risk of criminal justice involvement and victimization among homeless individuals with mental illness. Methods: The study used b...

Homeless individuals are at higher risk of criminal justice involvement (CJI) and victimization compared to their housed counterparts. Exposure to childhood maltreatment (CM; e.g., abuse, neglect) is one of the most significant predictors of CJI and victimization among homeless populations. The aim of this systematic review was to synthesize curren...

Background: Higher rate of Delay Discounting (DD) is associated with increased risk for the initiation and development of substance use disorders in adolescents. Objectives: This study aimed to provide a preliminary assessment of the validity of a brief self-report measure of DD by examining discounting rates across 3 periods of increasing delay...

Exposure to childhood maltreatment (CM) is associated with increased risk for developing substance use disorders (SUDs). CM exerts negative effects on cognitive abilities including intellectual performance, memory, attention, and executive function. Parallel cognitive impairments have been observed in SUDs. Hence, limited studies have examined the...

Numerous studies have identified differences in the identification of emotional displays between psychopaths and non-psychopaths; however, results have been equivocal regarding the nature of these differences. The present study investigated an alternative approach to examining the association between psychopathy and emotion processing by examining...

We examined the hypothesis that exposure to childhood maltreatment increases the vulnerability to Adult Victimization (AV) in a homeless population (N = 500). We also investigated the effects of specific types (emotional, physical, and sexual) and cumulative experience of childhood maltreatment on AV, and whether gender moderates these relationship...