Hamza Duygu

Near East University · Department of Cardiology

Whole-exome DNA sequencing is a rich source of clinically useful information for specialists, patients, and their families, as well as elucidating the genetic basis of monogenic and complex diseases in clinical diagnosis. However, interpreting and reporting variants encompassing exome and genome sequence analysis outcome data are one of the greates...

Objective: Atherosclerosis is a disease of the arteries that is not practically observed in veins. There are a lot of proposed mechanisms underlying this phenomenon. We aimed to compare the lipoprotein and total cholesterol levels in aortic and venous blood samples. Methods: A total of 125 patients ≥18 years of age were included in the study. Af...

Objective: Anxiety-depressive disorders are more common in patients with coronary artery disease (CAD) and are strongly associated with higher morbidity and mortality rates. The Hospital Anxiety and Depression Scale (HADS) is a wellvalidated diagnostic tool for screening of anxiety-depression disorders. The SYNTAX score (SS) is the angiographic sc...

A 27-year-old man applied for routine control due to aortic coarctation stent. During routine control, a late in-stent thrombus was detected. The patient was asymptomatic. Thrombus resolution was achieved with anticoagulant therapy. Anticoagulant therapy is one of the options in the treatment of aortic stent graft-associated asymptomatic thrombus....

Background In acute coronary syndrome (ACS) patients there are mostly studies evaluating prognostic value of admission heart rate. We tried to understand the prognostic value of discharge heart rate in a spectrum of ACS patients. Methods A total of 473 consecutive ACS patients were included in the study. Forty-three (9.1%) of them were unstable an...

Aims IQOS is a novel tobacco product claimed to be safer than conventional cigarette smoking due to the heat-not-burn system. This study aimed to evaluate the acute effects of IQOS smoking on myocardial systolic and diastolic functions and compare the acute impact of IQOS with cigarette smoking. Methods In this prospective study, twenty-seven heal...

Purpose: Arrhythmias are reproached for most of the sudden cardiac deaths in professional athletes. Also, performance-enhancing dietary supplements have been blamed in recent years. In this study, we aimed to investigate the effect of protein supplements (PS) on regular training athletes. Materials and Methods: 70 male sportsmen (30.0 ± 7.3 year) w...

Amaç: Kalp hızı değişkenliği (KHD), kalbin otonomik fonksiyonlarını yansıtan noninvaziv bir değerlendirmedir ve sistemik hastalıklarda bozulduğu bilinmektedir. Çalışmamızda, KHD ile akut iskemik inme (Aİİ) arasındaki ilişkiyi araştırmayı amaçladık.Materyal ve metod: Toplam 102 Aİİ hastası ve 66 sağlıklı birey (kontrol grubu) çalışmaya dahil edildi....

Background Regular physical activity is associated with cardiovascular health; however, intensive exercise can have harmful effects on the heart. Two‐dimensional (2D) speckle tracking echocardiography (STE) is a well‐established diagnostic tool to evaluate subclinical myocardial dysfunction and has been widely used in athletes in recent years. This...

Objective: There is a lack of data in the current literature regarding the spontaneous progression of inflammatory biomarkers early after cardiovascular implantable electronic device (CIED) placement. In our study we aimed to detect C-reactive protein (CRP) and white blood cell count (WBC) trends in the 5 days following CIED implantation. Methods:...

Background This study aimed to investigate serum 25[OH]D levels between patients with vasovagal syncope(VVS) diagnosed by head-up tilt table test (HUTT) and patients who do not develop syncope during the test. Methods Sixty-eight consecutive patients [mean age 33.2 ± 14.5 years, 49 females (72.1%)] were categorized based on their HUTT results (pos...

Background: In this study, we investigated whether the frontal QRS-T angle was different between the athletes and normal healthy people. Methods: The study included 122 healthy athletes (the mean age was 29.7±7.7 years, of them, were 73.8% male) and a control group consisted of 60 healthy people (the mean age was 29.8±7.8 years, of them, were 26...

Introduction: Atrial fibrillation (AF) is the most common chronic arrhythmia in the elderly population. In symptomatic patients, restoration and maintenance of sinus rhythm improve quality of life. Unfortunately, AF recurrence still occurs in a considerable number of patients after cardioversion (CV). In this study, we aimed to evaluate the associa...

Background: This study aimed to investigate serum 25[OH]D levels between patients with vasovagal syncope (VVS) diagnosed with head-up tilt table test (HUTT) and age-matched healthy people. Methods: The study included 75 consecutive patients (32.3 ± 10.7 years), who presented with syncope and underwent HUTT and 52 healthy controls (32.9 ± 14.1 ye...

Funding Acknowledgements none Background Exercise induced left ventricular remodelling is known for many years. Left ventricular enlargement, hypertrophy, left atrial dilatation are adaptive responsive mechanisms of myocardial tissue to increased physiological demand by exercise. In recent years, strain and strain rate have been used for the asses...

Funding Acknowledgements None Background Cigarette smoking effects myocardium with several mechanisms such as sympathetic nervous system activation, oxidative stress and endothelial dysfunction. Chronic smokers have an increased risk of morbidity and mortality associated with adverse cardiac events. Echocardiography is the well-established non-inv...

Iodine-related submandibular sialadenitis is a rare complication among the causes of sialadenitis. To date, the pathogenesis of iodide mumps has not yet been ascertained. This situation is a late reaction to iodinecontaining contrast agents and can manifest in any patient receiving iodinated contrast agents and repeated exposure. Fortunately, this...

Background: Cigarette smoking causes myocardial damage with several mechanisms such as sympathetic nervous system activation, oxidative stress, and endothelial dysfunction. Chronic smokers have an increased risk of morbidity and mortality associated with cardiac events. We aimed to compare the myocardial deformation parameters between chronic smok...

Escherichia hermannii is a microorganism very rarely isolated from clinical specimens, since its first identification in 1982. So far, there are around 17 human cases reported in medical sources. This small number of isolated case, eventually leads to a lack of information about the pathology and pathogenesis of infections caused by this microorgan...

Background: There is no consensus in the literature regarding what the responsible mechanism of left ventricular dyssynchrony is; septal dyskinesia or late movement of left ventricle (LV) lateral wall. We aim to evaluate the abnormal systolic motion in each myocardial segment and the improvement of LV systolic function with pulsed tissue Doppler I...

This study was prepared to determine the social sensitivity levels of secondary school students. 136 secondary school students studying in public and private schools in Alanya in 2018-2019 Academic Year, participated to study. The research was conducted as a descriptive study in the survey model and the data were analyzed as descriptively. Social S...

Coronary artery disease (CAD) is a common health problem with high morbidity and mortality. In recent years overt hypothyroidism is shown as an independent risk factor of CAD. Thyroid hormones have more effects on the cardiovascular system, and both hypothyroidism and hyperthyroidism have harmful effects on the cardiovascular systemc Subclinical hy...

BACKGROUND: The aim of this study was to evaluate of predictive value of vitamin D (vitD) for prediction of atrial fibrillation (AF) recurrence at follow-up in a group of our patients treated by balloon cryoablation. METHODS: A total of 63 symptomatic drug-refractory AF patients who underwent pulmonary vein isolation with second- generation cryobal...

Objective To evaluate the predictive value of mean perfusion pressure (mPP) in the development of acute kidney injury (AKIN) after transcatheter aortic valve implantation (TAVI). Methods One hundred and forty seven consecutive patients with aortic stenosis (AS) were evaluated for this study and 133 of them were included. Mean arterial pressure (mA...

Objective To evaluate the association of pulse pressure (PP) with mortality and major adverse cardiac events (MACE) in one-year period after anterior ST-elevation myocardial infarction (A-STEMI). Methods A total of 261 consecutive patients whose blood pressure was measured with the aid of a catheter before primary percutaneous coronary interventio...

Objective: To assess the relationship between preoperative vitamin D (vitD) supplementation and the development of postoperative atrial fibrillation (POAF). Methods: The study group consisted of 328 consecutive patients. The ınfluence of preoperative vitD supplementation on POAF was reviewed in 136 patients who underwent coronary artery bypass g...

BACKGROUND: Mitral annular calcification (MAC) one of the most common echocardiographic abnormalities. MAC is associated with atherosclerotic risk factors such as advanced age, diabetes mellitus, hypercholesterolemia, hypertension, female sex, and chronic kidney disease. SYntaX score (SS) is the angiographic scoring system and is commonly used to e...

BACKGROUND: The purpose of the study is to investigate the frequency of serum anti-Saccharomyces cerevisiae. Serum 25-hydroxyVitamin D (Vitamin D) deficiency or insufficiency has been implicated in endothelial dysfunction and cardiovascular disease via assumed mechanisms of renin-Angiotensin-Aldosteron system and modulation in levels of reactive ox...

Persistent left superior vena cava with absent right superior vena cava is a very rare venous anomaly and is known as isolated PLSVC. It is usually an asymptomatic anomaly and is mostly detected during difficult central venous access or pacemaker implantation, though it could also be associated with an increased incidence of congenital heart diseas...

Background Vitamin D deficiency is associated with many diverse cardiovascular disorders, such as hypertension, heart failure, stroke, coronary artery disease and atrial fibrillation. The relationship between Vitamin D and the development of atrial fibrillation after coronary artery bypass surgery (CABG) has not been studied. Therefore, we assessed...

We have read with great interest the paper by Witt et al. [(1)][1] that was recently published in JACC: Heart Failure . The investigators reported that patients with left bundle branch block and mildly to moderately reduced left ventricular ejection fraction (LVEF) have remarkably poor long-term

In recent years there has been an increase in clinical situations requiring lead extraction procedures of implanted cardiac devices. In our clinic, extraction procedures are performed with Evolution® mechanical lead extraction system. In this manuscript we aimed to evaluate our lead extraction procedures. We retrospectively evaluated lead extractio...

Background and Objectives The relationship of synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) score and development of atrial fibrillation (AF) after coronary artery bypass surgery (CABG) has not been studied. Therefore, we assessed the relationship between the SYNTAX score and development of AF after CABG...

AimsStatins have favourable effects on the vascular system. However, few data are available regarding the effect of these drugs on patients undergoing percutaneous coronary intervention (PCI). We sought to determine the impact of prior statin use on coronary blood flow after PCI in patients with stable coronary artery disease (CAD) by using the cor...

Background: Vitamin B 12 deficiency has been implicated in endothelial dysfunction and cardiovascular disease via hyperhomocysteinemia. Coronary tortuosity (CorT) is a common coronary angiography finding. The etiology, clinical implication and long term prognosis are still not well clarified. This study was conducted with the aim to evaluate the re...

We appreciated much for Dr. Cerit's comments on our article. Evidence from meta-analysis conducted by Kalantarian, et al.,[1] has suggested that AF is associated with a high risk of cognitive impairment (CI) and dementia (D), with or without a history of clinical stroke. Several mechanisms have been considered for the relationship of AF and CI. One...

Background: Vitamin B12 is required in the metabolism of homocysteine. Vitamin B 12 deficiency has been implicated in endothelial dysfunction and cardiovascular disease via hyperhomocysteinemia. However, the association of vitamin B12, and severity of coronary artery disease has not been studied up to date. This study was conducted with the aim to...

Although many of the ostium secundum atrial septal defects can be successfully closed by percutaneous transvenous approach, surgical method as well is preferred in some cases due to vascular reasons or due to the anatomical characteristics of the defect. Detecting ostium secundum atrial septal defect in a 26-year-old female patient, who presented w...

The treatment for subclavian artery stenosis includes the more common endovascular therapy rather than surgical intervention in symptomatic patients. We present a case of a 79-year-old man with coronary artery bypass graft where subclavian artery stenosis was found incidentally. In this asymptomatic case, we have merged clinical and multiple imagin...

Coraxel (Alvimedica) stents are among those that contain paclitaxel and differ from other paclitaxel eluting stents (PES) in the amount of drug they contain. In this context, it is not known whether the clinical effects of Coraxel stents are different or not. In this study, the clinical effects of Coraxel stents were studied. This study was a singl...

Primary spontaneous coronary artery dissection (SCAD) is a rare cause of acute coronary syndrome and is observed especially during gestation or the postpartum period of young healthy female patients. SCAD is much more rarely seen in young male patients. A 32year-old male was admitted to our clinic with a typical anginal complaint that had begun aft...

Background: Transvenous lead extraction is usually done via subclavian route, here we present an extraction case performed by femoral approach. Case report: 72 year old patient who has a VVI pacemaker with one passive fixation and one active fixation lead admitted to our clinic with pacemaker decubitus. We decided to remove all hardwares and insert...

In recent years, there has been an increase in clinical situations requiring extraction of leads of implanted cardiac devices. This study aimed to evaluate the Evolution Mechanical Dilator Sheath system, presently in use in our clinic for lead extraction procedures. Lead extraction procedures carried out on 20 patients (14 men, 6 women; mean age 61...

Atrioventricular nodal reentrant tachycardia (AVNRT) attacks is one of the common arrhythmias adversely affecting quality of life. The Umea 22 (U22) is a questionnaire developed for the assessment of symptoms associated with supraventricular tachycardia (SVT), and it is found to be effective in evaluation of quality of life after radiofrequency abl...

Transcatheter aortic valve implantation is becoming increasingly popular as an alternative treatment technique for symptomatic patients with severe aortic stenosis, who are at high risk for surgery. However, with this revolutionary treatment modality, some fatal complications have also emerged. One of these fatal complications is the occlusion of t...

Background: Atrial fibrillation (AF) after coronary artery bypass (CABG) surgery is associated with increased morbidity and mortality. The HATCH score was originally devised to predict the progression of paroxysmal AF to persistent AF. The aim of the present study was to determine whether HATCH score predicts the development of AF after (CABG) sur...

Background: The HATCH score predicts the development of persistent and permanent atrial fibrillation one year after spontaneous or pharmacological conversion to sinus rhythm in patients with atrial fibrillation (AF). However, it remains unknown whether HATCH score predicts short-term success of the procedure at early stages for patients who have u...

Objective: Percutaneous closure of perimembranous ventricular septal defects (pmVSD) has become an accepted alternative to surgical closure in selected cases. However, closure of pmVSDs associated with septal aneurysm is more challenging. We report our experience of device closure of pmVSDs associated with septal aneurysm. Methods: Between 2008...

Left ventricular (LV) thrombi usually occur in the presence of impaired LV function, such as in dilated cardiomyopathy, aneurysm or following myocardial infarction. Thrombus formation in a normally functioning LV is extremely rare. We report a patient with LV thrombus formation despite a normal systolic function. The patient, who was admitted to th...

Abstract We aimed to compare the effects of different types of hormone treatment (HT) on endothelial function by means of brachial artery ultrasonographic examination in postmenopausal women. Sixty-two healthy postmenopausal women were included in this study. Subjects were assigned to one of the five groups receiving 6 months of treatment [estrogen...