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Introduction
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Publications
Publications (25)
Background
Older persons with atrial fibrillation (AF) experience significant impairment in quality of life (QoL), which may be partly attributable to their comorbid diseases. A greater understanding of the impact of comorbidities on QoL could optimize patient-centered care among older persons with AF.Objective
To assess impairment in disease-speci...
Background:
Holistic care models emphasize management of comorbid conditions to improve patient-reported outcomes in treatment of atrial fibrillation (AF). We investigated relations between multimorbidity, physical frailty, and self-rated health (SRH) among older adults with AF.
Methods:
Patients (n = 1235) with AF aged 65 years and older were r...
Background: Geriatric conditions are common among patients with atrial fibrillation (AF) and relate to complications of oral anticoagulation (OAC).
Objective: To examine the prevalence of geriatric conditions among older patients with AF on OAC and relate type of OAC to geriatric conditions.
Methods: Participants had a diagnosis of AF, were aged ≥6...
Older adults account for an increasing percentage of trauma patients and have worse outcomes when compared with younger populations. Simple prediction tools are needed to designate risk categories among these patients. The Geriatric Trauma Screening Tool (GTST) was developed to risk stratify older adults admitted to the ICU at a Level 1 trauma cent...
Background: Data from previous studies that examined sex differences in the characteristics, clinical presentation, and management of patients with atrial fibrillation (AF) have been inconsistent.
Objective: To use data from a large contemporary cohort of older patients with AF to examine sex specific differences in baseline characteristics, sympt...
Takotsubo cardiomyopathy (TTC) was first described in Japan in the 1980s. It is described as an acute but often reversible left ventricular (LV) dysfunction mainly triggered by emotional or physical stress. Multiple variants of TTC have been reported including reverse Takotsubo cardiomyopathy (rTTC) which is a variant characterized by the basal aki...
[This corrects the article DOI: 10.1155/2018/1535049.].
Sarcoidosis is an inflammatory process of unknown etiology, characterized by noncaseating granulomas. Isolated extrapulmonary disease is rare. We present a case of a 60-year-old woman with chronically elevated alkaline phosphatase. Upon obtaining a liver biopsy, granulomatous hepatitis was observed, suggestive of sarcoidosis. No particular treatmen...
Background:
Evidence linking an elevated white blood cell count (WBCC), a marker of inflammation, to the development of atrial fibrillation (AF) after an acute coronary syndrome (ACS) is limited. We examined the association between WBCC at hospital admission, and changes in WBCC during hospitalization, with the development of new-onset AF during h...
Background:
Red blood cell distribution width (RDW) has been proved to be a strong prognostic marker in various diseases such as cardiovascular diseases, renal failure, viral hepatitis etc. But its prognostic value in acute pancreatitis (AP) remains controversial. The aim of this systematic review is to determine the prognostic value of RDW in AP....
The growing popularity of medical and recreational consumption of cannabis, especially among the youth, raises immediate concerns regarding its safety and long-terms effects. The cardiovascular effects of cannabis are not well known. Cannabis consumption has been shown to cause arrhythmia including ventricular tachycardia, and potentially sudden de...
The GRACE Risk Score is a well-validated tool for estimating short- and long-term risk in acute coronary syndromes (ACS). GRACE Risk Score 2.0 substitutes several variables that may be unavailable to clinicians and thus limit use of the GRACE Risk Score. GRACE Risk Score 2.0 performed well in the original GRACE cohort. We sought to validate its per...
Background:
As adults live longer, multiple chronic conditions have become more prevalent over the past several decades. We describe the prevalence of, and patient characteristics associated with, cardiac and non-cardiac-related multimorbidities in patients discharged from the hospital after an acute coronary syndrome.
Methods:
We studied 2,174...
Purpose of the study:
To examine differences in the characteristics, treatment practices and in-hospital outcomes of patients with and without previously diagnosed diabetes hospitalized for non-ST segment elevation myocardial infarction.
Key methods:
The study cohort consisted of 3916 patients diagnosed with non-ST segment elevation myocardial i...
Background: Hospital systems, patients and providers seek to avert rehospitalizations within 30 days for patients admitted with an acute coronary syndrome (ACS). Rehospitalizations within 30 days of discharge are often considered preventable and to reflect poor in-hospital management or discharge practices. However, independent associations of psyc...
Background: Diabetes mellitus is a major risk factor for coronary heart disease (CHD) and CHD related mortality. Despite improvements in the medical management of patients presenting with non-ST segment elevation myocardial infarction (NSTEMI), this condition is still associated with a poor prognosis among diabetic patients. The objectives of this...
Aims: To describe the characteristics, treatment, and mortality in patients with ST-elevation myocardial infarction (STEMI) by use of chronic oral anticoagulant (OAC) therapy.
Methods: Using data from the Global Registry of Acute Coronary Syndromes (GRACE), patient characteristics, treatment, and reperfusion strategies of STEMI patients on chronic...
Objectives:
Limited data are available describing the magnitude, clinical features, treatment practices, and short-term outcomes of younger adults hospitalized with an acute coronary syndrome (ACS).
Methods:
The objectives of this large multinational observational study were to describe recent trends in these and related endpoints among adult me...
Despite advances in the management of patients with an acute coronary syndrome (ACS), cardiogenic shock (CS) remains the leading cause of death in these patients. The objective of this observational study was to describe the characteristics, management, and hospital outcomes of patients with an ACS complicated by CS. Our secondary study objective w...
Background: Developing countries have been under-represented in multinational cardiovascular registries despite playing an important role in global cardiovascular burden. The Arab Middle East is a unique region of the developing world where little is known about the characteristics, clinical practices, and hospital outcomes of patients hospitalized...
Introduction: Cardiogenic shock (CS) is the leading cause of death for patients with an acute coronary syndrome (ACS). Despite impressive advances in the management of ACS, the frequency of CS among patients hospitalized with an ACS has remained relatively constant over the past several decades, and mortality remains unduly high in these high risk...
Introduction: Beginning in the late 1960s, the death rates attributed to coronary heart disease (CHD) in the U.S. declined, including deaths due to acute myocardial infarction (AMI). The decline in AMI related mortality is likely related to both a decrease in the incidence rates of new events in addition to declines in case-fatality rates (CFRs). T...
The Arab Middle East is a unique region of the developing world where little is known about the outcomes of patients hospitalized with an acute coronary syndrome (ACS), despite playing an important role in the global burden of cardiovascular disease. The primary objectives of this observational study were to compare patients with ACS hospitalized i...
Background Acute coronary syndromes (ACS) are a major cause of mortality and morbidity in the developed world. By 2020, ACS will be the leading cause of morbidity and mortality worldwide, largely due to substantial increases in ACS burden in developing countries. The developing world has been under-represented in international ACS registries. The A...
