Hamit Macit Selekler

• Professor of Neurology and Pain
• Professor (Full) at Kocaeli University

Algologists and neurologists play a significant role in management of headache. The study aimed to compare the headache management approaches of algologist and neurologists and evaluate the impact of telehealth education on their practices. A questionnaire was developed and sent to algologists and neurologists through social media and email. Demogr...

This study aimed to compare neuronal function in the lower limbs of elite footballers and an age-matched control group. Conduction velocity, response latency and amplitude following electrical stimulation were investigated. Thirty male football players and 30 untrained males comprised the subject and control groups, respectively. We showed that pro...

Background/hypothesis: Migraine affects >1 billion people but its pathophysiology remains poorly understood. Alterations in the trigeminovascular system play an important role. We have compared corneal nerve morphology in patients with migraine to healthy controls. Methods: Sixty patients with episodic (n = 32) or chronic (n = 28) migraine and 2...

During the COVID-19 pandemic, medical staff searched for opportunities to continue their education and contribute to patient care. Telemedicine provided that opportunity. Telemedicine is a valuable means for engaging medical staff in patient care, especially in times of crisis, and addressing the unique health system demands. The authors asked to e...

The etiology of Moyamoya Disease (MMD) is unknown. It is a cerebrovascular disease which is caused by occlusion or stenosis and can be diagnosed by angiographic methods. Digital Subtraction Angiography (DSA) is the gold standard for diagnosis, especially in cases with mild stenosis and few collateral lesions. The causes of this disease are unknown;...

Background and purpose: Migraine is a risk factor for ischemic stroke in women of childbearing ages. Previous researches revealed a higher prevalence of hyperhomocysteinemia in migraineurs. Possible differences on the frequencies of hyperhomocysteinemia between migraine with aura and migraine without aura could contribute the established variances...

Introduction Rowing is a strenuous sport that demands high levels of training, strength and repetitive motion. This study was conducted for assessing the impact of rowing act on the ulnar and median nerves which crosses the wrist area in elite rowers. Method Twenty asymptomatic professional male rowers and 20 non-active males were evaluated in thi...

Chronic migraine is a disabling, under-recognized, and undertreated disorder that increases health burdens. The aim of this study was to evaluate phenotypic features and the relevance of accompanying symptoms of migraine attacks in chronic migraine. This study was conducted as part of an ongoing Turkish Headache Database Study investigating the cli...

Introduction: The increased risk for psychiatric disorders in epilepsy can be related to a number of clinical, psychosocial and biological factors. Due to the unpredictability of seizures and the possibility that they may occur at any time and in any place, patients with epilepsy may develop social phobia and may have feelings of worthlessness and...

Gustatuar aura ile seyreden kompleks parsiyel epileptiknöbetli bir olguEpileptik auralar eski ça¤lardan beri tan›mlanmaktad›r. Olfaktor epi-leptik auralar oldukça nadir görülür. Tüm auralar›n yakla?›k %0,9’unuolu?turur. Tipik olarak ho?a gitmeyen ve rahats›zl›k veren kokular ?ek-linde duyulur. Hastalar›n büyük ço¤unlu¤u yak›c› bir his; sülfür, alko...

Primer bafla¤r›lar›nda büyük oksipital sinir injeksiyonu hakk›ndaki çal›flmalar Michael Anthony ile bafllam›flt›r ve bugün yap›lan çal›flmalar›n hemen hepsi Anthony’nin çal›flmalar›n› referans çal›flma olarak kabul ederler. Üzerinden yirmi y›l› aflk›n süre geçmesine karfl›n konu hakk›nda, yeterli say›da çal›flma bulunmamaktad›r. Mevcut verilere gör...

Primer başağrılarının tanısı başlıca klinik değerlendirmeye dayanır. Laboratuvar çalışmaları diğer hastalıkları dışlamak için kullanılır, tanıyı doğrudan desteklemez. Başağrısı tanısının doğru konulamamasının üç ana kaynağı vardır: kriterlerin esnekliği, toplanan bilginin değişkenliği ve yorum farklılıklarıdır. Kriterlerin esnekliği, tanı kriterler...

Amaç: Migren ataklar halinde giden baş ağrıları ve değişik organ sistemlerine ait belirtilerle kendini gösterir. Akut migren ataklarının tedavisinde kullanılacak uygun ilacın reçete edilmesi için baş ağrısının zamansal özellikleri bilinmelidir. Bu çalış- mamızda, üçüncü basamak bir sağlık kuruluşuna başvuran migrenlilerde baş ağrılarının zamansal ö...

Objectives: Patients with dilated cardiomyopathy (DCMP) and intracardiac Objectives: Patients with dilated cardiomyopathy (DCMP) and intracardiac spontaneous echo contrast (SEC) have an increased risk of thromboembolic events. Prevalence of silent cerebral infarction (SCI) has not been investigated in this patients group. The aim of this study is t...

In patients with diencephalic (thalamic-subthalamic) lesions, even if bilateral, coma often is only transient, evolving frequently to a sleeplike somnolence. In patients with diencephalic and mesencephalic pontine lesions, disturbance of conciousness is due to direct disruption of the ascending reticular activating system in the tegmentum. In patie...

Çocukluk çağı migreni yaşa ilişkin özellikler taşır.

Posterior reversible encephalopathy syndrome (PRES) is a rare clinical and radiological entity of neurological origin which has different etiologies. A 27-yearold male patient with a history of type 1 diabetes, uncontrolled hypertension and chronic renal failure presented to the emergency department with complaints of confusion, high blood pressure...

The chronic form of paroxysmal hemicrania was defined first. Although the episodic form was thought to be inevitably chronic, in time, episodic forms that never reach the chronic phase were identified. The supposed incidence of paroxysmal hemicrania is 1/50.000, and the ratio of the episodic to chronic form is 1:4. A seasonal type of episodic form,...

Neuroleptic malignant syndrome (NMS) is a potentially fatal disease composed of hyperthermia, extrapyramidal symptoms, autonomic nervous system disturbances, and altered levels of consciousness. Although the cause is still uncertain, most studies suggest it is the result of dopaminergic deficiency in the central nervous system, most commonly caused...

Objective: Migraine is a recurrent primary headache disorder characterized by different clinical presentations. Migraneurs report excessive sensitivity to light, sound, motion, odours, and other sensory stimuli in and between acute migraine attacks. This study was undertaken to document different trigger factors and to evaluate the differences in e...

Background: Headache disorders cause substantial productivity losses through absenteeism and impaired effectiveness at work (presenteeism). We had previously found these losses to be high in a mostly male, heavy-manufacturing workforce at Ford Otomotiv Sanayi AŞ (FO), in north-western Turkey. Here we aimed to confirm this finding in a year-long st...

Migren de¤iflik nörolojik, gastrointestinal ve otonomik de¤iflikliklerin efllik etti¤i bir epizodik bafla¤r›s› bozuklu¤udur. Migrenlilerin beflte birinde bafla¤r›s›n›n geliflimi esnas›nda veya öncesinde migren auras› ad› verilen bir nörolojik bozukluk (vizüel, duyusal veya motor) ortaya ç›kar. Kortikal yay›lan depresyon (CSD); bir odaktan bafllay›p...

OLGU SUNUMU: MEZENSEFALİK UZANIMLI BÎLATERAL TALAMİK İNFARKT* D iensefalik ( talam ik-subtalam ik) lezyonlu hastalarda, lezyon bilateral olsa bile, kom a sıklıkla geçicidir; çoğunlukla takiben som - nolans görü lü r. D iensefalik ve m ezensefalik pontin lezyonlu h astalarda şuur bozuklukları tegm en tum daki asen dan retiküler aktive edici sistem i...

Trigeminal otonomik sefaljiler-küme bafla¤r›s›, paroksismal hemicrania (PH), hemicrania continua (HC) ve SUNCT (short-lasting unilateral headache attacks with conjunctival injection and tearing) - ünilateral a¤r›ya efllik eden ipsilateral otonomik bulgular ile karakterizedirler. Küme bafla¤r›s›n›n oturmufl bir medikal tedavisi mevcuttur. Bununla be...

Amaç: Bu çal›flmada epizodik ve kronik migrenlilerde, depresyon ve uyku kalitesi sorgulanarak, aralar›ndaki iliflki ve tedavide yol gösterici ipuçlar› bulmak amaçland›. Yöntemler: Çal›flmaya, 66 migren ve 65 kronik migrenli hasta dahil edildi. Bu hastalarda; uykuya dalma süresi, uykuyu sürdürme, toplam uyku süresi ve uykunun dinlendirici özelli¤i s...

Dondurma bafl a¤r›s›na migrenlilerde daha s›k rastlan›r. Muhtemelen bu, migren hastalar›nda nöral ve vasküler sistem aras›ndaki spesifik etkileflim nedeniyledir. Dondurma bafl a¤r›s› hikayesi bulunan iki hasta migren ataklar› s›ras›nda da s›cak ve gazl› içeceklerle benzer nitelikte bir a¤r›n›n olufltu¤unu bildirdiler. Materyalin yutulma h›z› ve ›s›...

Migren Koruyucu Tedavisi İlkeleri ve Koruyucu tedavide Kullanılan İlaçlar

Objective: Depression frequently occurs in patients with heart failure as similar pathophysiological mechanisms present in both these diseases. Patients with dilated cardiomyopathy (DCM) have a high incidence of clinically asymptomatic silent cerebral infarction (SCI). This study aimed to evaluate the relation between SCI and major depressive diso...

Repetitive microtrauma or overuse injuries may often affect upper extremities of the long term computer users. The aim of this study was to compare sensory nerve conduction velocities (SNCV) for median, radial and ulnar nerves in the wrist of computer users with the same parameters in controls who do not use computers regularly. Twenty one male com...

Background : Many sports are associated with a variety of peripheral nervous system injuries that are specific to that particular sport. Research question : The purpose of this study was to evaluate the influence of playing basketball on nerves in the elbow region. Type of study : This is a comparative study that focuses on nerve conduction velocit...

AimChronic migraine is a growing and disabling subtype of migraine with different risk factors and clinical features, even in older adults. We sought to define and differentiate clinical features of chronic migraine in older adults. We also aimed to compare major clinical features of chronic migraine in older adults with those in younger people of...

Introduction: The increased risk for psychiatric disorders in epilepsy can be related to a number of clinical, psychosocial and biological factors. Due to the unpredictability of seizures and the possibility that they may occur at any time and in any place, patients with epilepsy may develop social phobia and may have feelings of worthlessness and...

Headache disorders cause substantial productivity losses through absenteeism and impaired effectiveness at work (presenteeism). We used the HALT Index as the survey instrument. We first assessed productivity losses by surveying the entire workforce. Because we anticipated much non-participation, we also applied HALT at the annual health-checks prov...

Objective: Rapid eye movement (REM) sleep behavior disorder (RBD) is a type of REM parasomnia characterized by complex motor activity during REM sleep. In this study, cyclic alternating pattern (CAP) in patients with idiopathic RBD was analyzed to evaluate the expression of arousal instability of NREM sleep. Methods: A total of 31 idiopathic RBD...

Vertigo, dizziness and visual blurring have been reported in painful conditions in trigeminal innervation zones such as in idiopathic stabbing headache, supraorbital neuralgia or trigeminal nerve ophthalmic branch neuralgia. Although not common, pain in occipital neuralgia can spread through the anterior parts of the head. In this article, we prese...

Some studies have found elevated alexithymia among patients with chronic pain, but the correlations between alexithymia and the severity of pain, depression, and anxiety among migraine patients are unclear. The aims of the present study were to investigate whether individuals suffering from episodic migraine (EM) differ from those with chronic migr...

The chronic form of paroxysmal hemicrania was defined first. Although the episodic form was thought to be inevitably chronic, in time, episodic forms that never reach the chronic phase were identified. The supposed incidence of paroxysmal hemicrania is 1/50.000, and the ratio of the episodic to chronic form is 1:4. A seasonal type of episodic form,...

Objective: Migraine is a recurrent primary headache disorder characterized by different clinical presentations. Migraneurs report excessive sensitivity to light, sound, motion, odours, and other sensory stimuli in and between acute migraine attacks. This study was undertaken to document different trigger factors and to evaluate the differences in e...

Objective: In this study, depression and sleep quality were investigated inepisodic migraine and chronic migraine patients in order to determine the relationshipbetween them and to find clues to treatment.Methods: Sixty-six migraine and sixty-five chronic migraine patients wereincluded in the study. Sleep latency, maintaining sleep, total sleeping...

Trigeminal autonomic cephalgias - cluster headache, paroxysmal hemicrania (PH), hemicrania continua (HC) and SUNCT (short-lasting unilateral headache attacks with conjunctival injection and tearing)-are characterized by ipsilateral autonumic features accompanying the unilateral headache. A well-established medical treatment exists for cluster heada...

Migraine is characterized by headache attacks, and symptoms belong to various organ systems. Temporal characteristics of headache must be known to prescribe the appropriate drug for the treatment of migraine attacks. In this study, we aimed to reveal the temporal characteristics of headache and to search whether or not these characteristics differ...

Poster presented in 10th Congress of European Association of Clinical Anatomy

The peripheral nerves of the upper extremity are exposed to acute and chronic mechanical injuries in ice hockey players, because of the high repetition of motions, high muscular forces and extreme shoulder positions. This study was performed to evaluate the effect of ice hockey playing on the axillary, musculocutaneous and radial nerves crossing th...

In researches where two or more groups are desired to be compared, observational and randomized experiments are very frequently used. As the subjects are randomly assigned to the groups in randomized experiments, balance is provided in observed/unobserved covariates of subjects in different groups. As the subjects cannot be randomly distributed int...

We present a male with headache related to sexual activity. An injection of steroid and local anesthetic combination was applied to the greater occipital nerve of the symptomatic site. The orgasmic headache stopped after the procedure.

Studies about greater occipital nerve injection in primary headaches had begun with Michael Anthony and almost all the studies today accept Anthony's studies as reference work. Although more than twenty years passed, there is not enough study about the subject. According to the present data, steroids are apparently effective in both preventive and...

Patients with dilated cardiomyopathy (DCM) may have a high incidence of clinically asymptomatic silent cerebral infarction (SCI). Prevalence of SCI and its risk factors may differ between ischemic and nonischemic DCM. The purpose of this study was to evaluate prevalence and related parameters of silent cerebral infarction in patients with ischemic...

KLİNİK EEG ATLASI

Cortical spreading depression (CSD) is supposed to be the underlying biological basis of the migraine aura. Metoprolol was proven to be effective in migraine prophylaxis in clinical trials, but its mechanism of action has not been clarified yet. We studied direct effects of metoprolol on a continuous CSD induction model in rats. Six adult Wistar ra...

Tramadol, an atypical opioid, is a narcotic analgesic used for pain management. A search of the current literature found no studies examining the efficacy of intravenous tramadol on migraine pain. The aim of this study was to investigate the efficacy and tolerability of a single dose of intravenous tramadol hydrogen chloride 100 mg in comparison wi...

We report on a patient with 7-year history of short-lasting paroxysmal nonkinesigenic dyskinesia. The episodes occurred 100 to 125 times per day, lasted from 5 seconds to 3 minutes, and were not suppressed with sleeping, underlining the heterogeneity of phenomenology in paroxysmal dyskinesias. Neuroimaging studies showed calcifications in the basal...

Sorry, there is no abstract.

Migraine is an episodic headache disorder accompanied by various neurological, gastrointestinal and autonomic changes. In one fifth of the migraineurs, a neurological disturbance (visual, sensory or motor) appears during or before the development of the headache called migraine aura. Cortical spreading depression (CSD) is a transient neuronal depol...

Patients with dilated cardiomyopathy (DCM) have an increased risk of thromboembolic events. Incidence of silent cerebral infarction (SCI) has not been investigated in these patients. The aim of this study was to investigate the incidence of SCI in patients with DCM and to determine its associations with echocardiographic parameters. Seventy-two pat...

Migraine and cortical spreading depression Migraine is an episodic headache disorder accompanied by various neurological, gastrointestinal and autonomic changes. In one fifth of the migraineurs, a neurological disturbance (visual, sensory or motor) appears during or before the development of the headache called migraine aura. Cortical spreading dep...

Isolated abducens nerve palsy is a rare complication of treatment with various drugs. Here, the authors report the case of a 23-year-old female with isolated left abducens nerve palsy after long-term retinoic acid therapy. The association is based on the temporal relationship and the exclusion of other possible etiologic factors following extensive...

Neurological disorders of different etiology may cause identical clinical symptoms requiring additional diagnostic procedures for a precise differential diagnosis. Focal epileptic seizures have been shown to cause increased signal intensities in T2 and diffusion-weighted magnetic resonance images (MRI), mimicking other neurological disorders or dis...

Ice cream headache is more frequent in migraineurs. This is probably due to the specific interactions between neural and vascular systems in migraine patients. Two patients suffering from ice cream headache reported us that a similar headache occurred during migraine attacks with various stimuli such as ingesting hot and fizzy drinks. In addition t...

Due to their localisations and symptoms, interhemispheric subdural haematomas (ISH) compose a distinct category. Altered level of consciousness and hemiparesis are the most frequent symptoms. We report a case of ISH who presented with headache as the sole complaint. Left cerebellar haematoma and ISH were found in cranial MRI and cranial computed to...

Temporal and spatial relationships between idiopathic stabbing headache and migraine headache have so far been reported. We aimed to obtain some clues about the stabbing headache pathophysiology by comparing the two types of headache in regard to temporal and spatial relationships as well as precipitating and relieving factors of stabbing headache...

Inappropriate use of headache medication (>15 times/month) for the treatment of headache episodes may contribute to the development of chronic headache which is refractory to most treatments. Physicians experienced in the treatment of migraine and other headaches are well aware that the daily intake of antipyretic or antiinflammatory analgesics, op...

Epileptic auras have been recognized in the literature since antiquity. Olfactory epileptic auras are very rare, constituting about 0.9% of all auras, and are typically described as unpleasant experiences. Most patients specifically likened it to a familiar smell such as that of burning, sulphur, alcohol, gas, barbecue, peanut butter, or toothpaste...

We wanted to document Turkish migraine sufferers unconventional therapy methods learnt from their social environment and discuss the historical background and possible action mechanisms of these methods. Unconventional therapy methods were documented among 482 migraine patients who consulted Kocaeli University Medical Faculty, Neurology Departments...

Trigeminal autonomic cephalgias; cluster headache, paroxysmal hemicrania, hemicrania continua and SUNCT (short-lasting unilateral neuralgiform headache attacks with conjuctival injection and tearing) syndrome are characterized by unilateral trigeminal distribution of pain and accompanying ipsilateral autonomic symptoms. Other than cluster headache,...

Using a standard questionnaire, 121 consequent epileptic patients have been evaluated sociodemographically and according to their beliefs and behaviours about their illness. Monthly income per person was between 26 and 62.5 U.S. dollars (USD) for 3/4 of the patients. About half of the patients were concealing their illness. About one third of the p...

A 23-year-old woman consulted with the complaint of short-lasting, severe stabbing headaches and mild-to-moderate degree near-daily migrainous headaches. Further questioning revealed that she also had stabbing pain on both ipsilateral hand and calf. Stabs on the hand were time-locked to cephalic ones and stabs in the calf were alternating with the...

While questioning patients about aggravation of the headache by routine physical activity, sensitivity of walking stairs and lifting a heavy object versus head movements and bending down in terms of aggravating the headache was aimed to be determined. Eighty-one migraine patients were questioned about the aggravation of their headaches with two set...

This study was designed to compare the prevalence and clinical characteristics of 'cold-induced headache' between migraine and episodic tension-type headache patients. Seventy-six migraine and 38 episodic tension-type headache patients were included in the study. An experimental model of an 'ice-cream headache' was developed for the study. The pain...

Idiopathic stabbing headache (ISH) and ice cream headache occur due to paroxysmal firing of trigeminal pathways and a defect in pain control mechanisms. Any defect in pain control mechanisms appears to be localized to the affected areas. Therefore, we compared ISH and experimentally induced ice cream headache localizations in the same group of migr...

Objective: The purpose of this report is to evaluate the clinical signs, manipulations in emergency room and cranial imaging findings in the cases with brain stem infarction. Method: The signs and symptoms, underlying risk factors, manipulations in emergency room, cranial imaging findings and prognosis of six patients who admitted to the Hospital o...

In this study, we aimed to discuss how specific Turkish migraineurs’ the most severe headache attack descriptions are to socio-cultural background and how universal these descriptions are. Consecutive 99 patients who met International Headache Society’s “migraine without aura” criteria were required to give a short comment on their most severe head...

Epileptic auras have been recognized in the literature since antiquity. Olfactory epileptic auras are very rare, constituting about 0.9% of all auras, and are typically described as unpleasant experiences. Most patients specifically likened it to a familiar smell such as that of burning, sulphur, alcohol, gas, barbecue, peanut butter, or toothpaste...

The aim of this study was to determine postures adopted by patients during migraine attack. A total of 199 migraine patients were questioned about their postures during the migraine attack. Of these, 92 patients did not choose a specific lying position, 22 could not lie down during the attack because of the increase in pain, while 6 avoided lying d...

Objective: It could not be possible to diagnose headache patients according to IHS criteria in the first interview. In this study, rate of ending up with the definite diagnosis was investigated in the follow-up of these patients. Methods: The twenty two patients taken in this study suffered from headaches which include migraine symptoms and the cli...

Başağrısı ile Mücadelede Seçilen İlaç-Dışı Tedavi Yöntemleri

BACKGROUNDTriphasic waves generally occur in patients with hepatic encephalopathy. Most EEGers agree that triphasic waves, typical or atypical, can also occur in various toxic-metabolic encephalopathies other than hepatic encephalopathy. We presented a patient with INH intoxication with triphasic waves in the EEG. The best of our knowledge, this pa...

Greater occipital nerve blockade: Trigeminicervical system and clinical applications in primary headaches Studies about greater occipital nerve injection in primary headaches had begun with Michael Anthony and almost all the studies today accept Anthony's studies as reference work. Although more than twenty years passed, there is not enough study a...

Objective: The purpose of this report is to evaluate the clinical signs, manipulations in emergency room and cranial imaging findings in the cases with brain stem infarction. Method: The signs and symptoms, underlying risk factors, manipulations in emergency ro- om, cranial imaging findings and prognosis of six patients who admitted to the Hospital...