Hamide Z Senyuva

Hamide Z Senyuva
FoodLife International Ltd · R&D

PhD

About

84
Publications
18,882
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2,995
Citations
Citations since 2017
5 Research Items
1233 Citations
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
2017201820192020202120222023050100150200
Introduction
Founder and General Director of FoodLife International Ltd.(www.foodlifeint.com), a food safety consultancy company established in Turkey but operating in UK, Austria, Germany and USA. This company has multi-national clients (Turkey, Germany, UK, USA, Italy, China, Serbia, Jamaica and Japan) and operates through a network of extensive international links.

Publications

Publications (84)
Article
Full-text available
Fungal metabolites including regulated mycotoxins were identified by a validated LC-MS/MS method in 180 individual Turkish dried figs from 2017 and 2018 harvests. Hand-selected dried figs were subjectively classified based on the extent of fluorescence. Forty-three fungal metabolites including eight EU-regulated mycotoxins were identified and quant...
Article
Despite the availability of a large number of antibody and DNA based methods for detection and quantification of allergens in food there remain significant difficulties in selecting the optimum technique to employ. Published methods from research groups mostly contain sufficient detail concerning target antigen, calibration procedures and method pe...
Article
Although herbal ingredients could be used to increase bioactive compounds in food products, it is more crucial to investigate the effect of processing on their bioaccessibility and their content. In this study, artichoke leaf powder (ALP) was added to wheat flour (WF) at ratios of 0:100, 3:97, 6:94 and 9:91 g ALP:g WF on dry basis. The effect of ex...
Article
A method validation study for the determination of ochratoxin A in black and white pepper (Piper spp.), nutmeg (Myristica fragrans), spice mix (blend of ginger, turmeric, pepper, nutmeg, and chili), cocoa powder, and drinking chocolate was conducted according to the International Harmonized Protocol of the International Union of Pure and Applied Ch...
Article
As part of an EU-funded project (FP7) developing 'Integrated approaches to food allergen and allergy management' a database was constructed based on publicly available information on food allergen recalls in Europe, North America, Hong Kong, Australia and New Zealand. Over 2000 entries were made into the database. The database covers a 4-year perio...
Article
We have conducted a literature search from 2007-2014 to identify publications where principally LC-Orbitrap™ high resolution mass spectrometry (HRMS) has been employed in food analysis. Of a total of 212 relevant references, only 22 papers were from the years 2007-2010, but in subsequent years there has been a steady growth in publications with 38...
Article
To screen for possible illegal use of soybeans in meat products, the performance characteristics of a commercial polymer chain reaction (PCR) kit for detection of soybean DNA in raw and cooked meat products were established. Minced chicken and beef products containing soybean at levels from 0.1% to 10.0% were analysed by real-time PCR to amplify th...
Article
A wide range of plant and fungal metabolites can occur in cereals and feed but only a limited number of target compounds are sought. This screening method is using a database of over 600 metabolites to establish contamination profiles in food and feed. Extracts were injected directly into an automated turbulent flow sample clean-up system, coupled...
Article
An automated sample preparation technique involving cleanup and analytical separation in a single operation using an online coupled TurboFlow (RP-LC system) is reported. This method eliminates time-consuming sample preparation steps that can be potential sources for cross-contamination in the analysis of plasticizers. Using TurboFlow chromatography...
Article
From 2008 to 2011, surveys were conducted to determine the levels of benzoic and sorbic acids and their respective salts in 983 retail food samples which included sauces, vegetable and fruit preparations, flavoured syrups, food supplements, cereals, bakery products, jelly, synthetic cream, sprays, mustards, jam and preserves, molasses, chewing gum,...
Article
The method performance characteristics of commercially available PCR kits for animal species identification were established. Comminuted meat products containing different levels of pork were prepared from authentic beef, chicken, and turkey. These meat products were analysed in the raw state and after cooking for 20min at 200°C. For both raw and c...
Chapter
Analysis of foods is exceptionally challenging because of the complexity of the matrices, and the need to determine residues and contaminants at very low levels. Trace analysis for organic analytes comprises (1) representative sampling; (2) sample preparation and homogenization; (3) sample cleanup; (4) chromatography; and (5) identification and qua...
Article
A multi-class method for identification and quantification of 36 antibiotics from seven different chemical classes (aminoglycosides, macrolides, lincosamides, sulfonamides, tetracyclines, quinolones and trimethoprim) has been developed by using liquid chromatography-mass spectrometry. The method was optimised for detection of antibiotics in chicken...
Article
This paper describes an on-line sample preparation method for the simultaneous determination of 48 pesticides in grapes, baby food and wheat flour matrices. Target pesticides were selected to represent a wide variety of chemical structures and three typical matrices were selected. Turbulent flow chromatography was applied for on-line sample cleanup...
Article
A comparison has been made of an LC/MS/MS method using direct analysis of acetonitrile extracts of feed and cereal samples and a method using acetonitrile extraction and subsequent immunoaffinity column (IAC) cleanup. Naturally contaminated samples containing one or more of deoxynivalenol, zearalenone, T-2, and HT-2 toxins were analyzed together wi...
Article
An automated method involving on-line clean-up and analytical separation in a single run using TurboFlow™ reversed phase liquid chromatography coupled to a high resolution mass spectrometer has been developed for the simultaneous determination of deoxynivalenol, T2 toxin, HT2 toxin, zearalenone and fumonisins B1 and B2 in maize, wheat and animal fe...
Article
A fast and reliable multiresidue method is reported for the identification and quantification of 36 different compounds from seven different classes of antibiotics (aminoglycosides, sulfonamides, macrolides, quinolones, tetracyclines, lincosamides and trimethoprim) in milk. Automated online sample cleanup was applied using turbulent flow chromatogr...
Article
A single-laboratory validation was conducted to establish the effectiveness of an immunoaffinity column cleanup procedure followed by LC with fluorescence detection for the determination of aflatoxins B1, B2, G1, and G2 in sesame seeds. The sample is homogenized with 50% water (w/w) to form a slurry, then the test portion is extracted with methanol...
Chapter
A survey on Alternaria toxins in the food categories dried figs (n ¼ 14), sunflower products (n ¼ 24) and tomato products (n ¼ 43) was carried out in the Netherlands on samples collected in retail stores in autumn 2014. The occurrence data from this survey confirmed the previously reported data of a pilot survey in 2013, with tenuazonic acid being...
Article
A cloud point extraction method is reported using LC/MS for the determination of regulated water-soluble food colors (Allura Red, Sunset Yellow, erythrosine, and tartrazine) and banned fat-soluble synthetic azo dyes (Sudan I, II, III, and IV; Red B; 7B; Black B; Red G; Metanil Yellow; and Rhodamine B). The extraction of all 14 colors was carried ou...
Article
A commercially available real-time PCR, based on a multi-copy target cytochrome b (cyt b) using porcine specific primers, has been validated for the Halal/Kosher authentication of gelatine. Extraction and purification of DNA from gelatine were successfully achieved using the SureFood® PREP Animal system, and real-time PCR was carried out using Sure...
Article
Surveys were carried out between 2007 and 2010 to determine the total levels of sulfites in 1245 samples of wines, dried apricots, dried vegetables, nuts, juices and purees, frozen foods and cereals containing dried fruit supplied by food inspectors and by food producers for testing or for export certification. Sulfite analysis of wine was carried...
Article
A method was developed using automated headspace solid-phase microextraction coupled with GC/MS/MS to simultaneously determine the presence of seven biologically active flavoring substances whose levels of use in processed foods is controlled by statutory limits. The method can be applied to identify and quantify the presence of 1,2-benzopyrone (co...
Article
Full-text available
A liquid chromatographic method for the determination of fumonisins B1 (FB1) and B2 (FB2) in corn-based foods for infants and young children was subjected to an interlaboratory validation study involving 11 laboratories. Five blind duplicate sample pairs of each matrix were analyzed to establish the accuracy, repeatability, and reproducibility of t...
Chapter
The concept of a criteria-based approach for regulatory methods has been adopted in Europe by the European Commission and worldwide by Codex Alimentarius. For mycotoxins in food and feed, EU Directives stipulate that only validated methods can be employed for enforcement purposes and stipulate the minimum performance characteristics such methods mu...
Article
A simple, rapid, accurate and robust liquid chromatography / mass spectrometry (LC/MS) method was developed for the determination and quantification of the solanapyrones and new metabolites. Portions of the crude solvent extracts of culture filtrate from Ascochyta rabiei, agent of chickpea blight were also analysed for confirmation by combined LC w...
Article
Full-text available
A simple, rapid, accurate and robust liquid chromatography/mass spectrometry (LC/MS) method was developed for the determination and quantification of the solanapyrones and new metabolites. Portions of the crude solvent extracts of culture filtrate from Ascochyta rabiei, agent of chickpea blight were also analysed for confirmation by combined LC wit...
Article
Surveys were carried out between 2007 and 2009 to determine the aflatoxin B1 content of 3345 commercial Turkish foodstuffs supplied by producers for testing for their own purposes or for export certification. To simplify the reporting of data, foods were categorized as: 1, high sugar products with nuts; 2, nuts and seeds; 3, spices; 4, grain; 5, co...
Article
Full-text available
An interlaboratory validation study was conducted to establish the method performance characteristics of an immunoaffinity column (IAC) cleanup procedure followed by LC/MS for the determination of fumonisins B1 (FB1) and B2 (FB2) and combined FB1 + FB2 in corn. The test portion is extracted with acetonitrile-methanol-water (25 + 25 + 50). The extra...
Article
Full-text available
The effectiveness of an affinity column cleanup procedure followed by LC with fluorescence detection was established for the determination of aflatoxins and ochratoxin A in high-sugar-content traditional Turkish foods. Traditional foods, such as baklava (finely layered pastry filled with nuts and steeped in syrup), halvah (containing sesame paste a...
Article
This review provides a critical assessment of the applications of immunoaffinity columns for sample clean-up in the field of food safety. The performance of immunoaffinity columns are compared in terms of specificity, binding capacity and recovery, and commercial disposable columns are contrasted with home-made columns. Areas covered include multip...
Article
Seventy authentic honey samples of 9 different floral types (rhododendron, chestnut, honeydew, Anzer (thymus spp.), eucalyptus, gossypium, citrus, sunflower, and multifloral) from 15 different geographical regions of Turkey were analyzed for their chemical composition and for indicators of botanical and geographical origin. The profiles of free ami...
Article
Upon the discovery of acrylamide in foods, international authorities and experts concludedthat the presence of acrylamide was a major concern and additional research on mechanismsof formation and toxicity was seriously needed. However, it is still not really known theextent to which acrylamide consumption poses a health risk. Meanwhile, an earlier...
Chapter
Inherent toxicants and processing contaminants are both non-essential, bioactive substances whose levels in foods can be difficult to control. This volume covers both types of compound for the first time, examining their beneficial as well as their undesirable effects in the human diet. Chapters have been written as individually comprehensive revie...
Article
An aqueous slurry of gamma-irradiated sterilized dried figs was inoculated with toxigenic strains of Aspergillus flavus and Aspergillus parasiticus. During incubation at 28 degrees C, pH, fructose, glucose, and free amino acids were determined by high-performance liquid chromatography and liquid chromatography (LC)/mass spectrometry, respectively,...
Article
Full-text available
Dried figs from Turkey that were visibly moldy (or fluorescent under UV light) and thus rejected as unsuitable for human food were screened for the presence of fungal metabolites. Crude solvent extracts from individual figs were directly analyzed by liquid chromatography combined with time-of-flight mass spectrometry to generate accurate mass data...
Article
Affinity column clean-up of food samples for mycotoxin analysis produces extracts which are free of co-extractives and therefore require little chromatography for separation and quantification of the target analytes. Using such clean extracts, we report rapid chromatographic methods for aflatoxins B(1), B(2), G(1) and G(2), aflatoxin M(1), ochratox...
Article
Full-text available
A liquid chromatography-time-of-flight mass spectrometry (LC/TOF-MS) method has been developed for profiling fungal metabolites. The performance of the procedure in terms of mass accuracy, selectivity (specificity) and repeatability was established by spiking aflatoxins, ochratoxins, trichothecenes and other metabolites into blank growth media. Aft...
Article
Full-text available
A single-laboratory method validation was conducted to establish the effectiveness of an immunoaffinity column cleanup procedure followed by liquid chromatography/mass spectrometry (LCIMS) for the determination of fumonisins B1 and B2 (FBI + FB2) in corn. The test portion is extracted with acetonitrile-methanol-water (25 + 25 + 50). The extract is...
Article
Full-text available
Marked Items Alerts Order History Saved Items All Back to:Journal\Journal Issue Previous Article Next Article Journal Article Occurrence of fungi and their mycotoxins in individual Turkish dried figs Journal World Mycotoxin Journal Publisher Wageningen Academic Publishers ISSN 1875-0710 (Print) 1875-0796 (Online) Subject Biotech...
Article
Full-text available
Fifty individual figs which had been rejected as potentially contaminated by sorting under UV light were separately analysed to identify the presence of fungi and their mycotoxins. Aflatoxin B-1 was found in 49 samples with levels ranging from 0.7 to 222 ng g(-1), with 40 individual figs containing more than 2 ng g(-1), indicating the efficacy of t...
Article
The effects of mono- and divalent cations on the formation of acrylamide were studied in a fructose-asparagine model system at 150 and 180 °C. At amounts equivalent to those of asparagine and fructose, added divalent cations, such as Ca2+, were found to prevent acrylamide formation completely, whereas monovalent cations, such as Na+, almost halved...
Article
In this study, digital colour images of fried potato chips and french fries were analyzed to estimate acrylamide levels based on the correlation with analyses using liquid chromatography-mass spectrometry. In fried potato images, bright yellow (Region 1), yellowish brown (Region 2) and darker brown (Region 3) regions were clearly visible, having di...
Article
A recent patent application and some other studies showed that there is a relation between acrylamide formation and cations. In fact, to date, there is no concrete evidence on the formation or elimination of some compounds in foods and current hypotheses are based only on observations in model systems. To find that this is a logical explanation, we...
Article
Full-text available
Dried figs for export from Turkey from crop years 2003 through 2006 were tested for aflatoxin B1 and total aflatoxins. For export to the European Union, consignments of 0.5 to 10 tonnes of dried figs were sampled according to European Commission regulations, and high-pressure liquid chromatography (HPLC) was used to determine concentrations of afla...
Article
The formation of furan as influenced by temperature and time of heating was studied in hazelnuts. Temperature was noted as the important processing parameter on the formation of furan in hazelnuts. The formation of furan was noticeably increased at temperatures exceeding 120 degrees C. Furan concentrations tended to increase linearly at 100 and 150...
Article
In this study, the effect of microwave pre-cooking of potato strips on the resultant acrylamide levels in French fries was investigated. Control and microwaved (10, 20, and 30 s at 850 W) samples were fried at 150, 170 and 190 degrees C for predetermined times. Surface and core temperatures of potato strips were acquired during frying, and acrylami...
Article
The effects of heating on colour generation measured as CIE colour space parameters of L* a* b* and acrylamide formation were studied in various food matrices including green coffee, wheat flour and potato chips at different temperatures. Changes in both the acrylamide concentration and the redness parameter a* during heating at relatively higher t...
Article
This paper investigates the effect of frying time and temperature on acrylamide formation in the surface and core regions of French fries. Surface and core temperatures of the potato strip were monitored during frying at 150, 170 and 190 °C. The core temperature did not exceed 103–104 °C within 9 min of frying regardless of the frying temperature,...
Article
An improved analytical method which offers rapid, accurate determination and identification of 22 amino acids in a variety of matrices, e.g. baby foods, juices, honey is reported. The amino acids were extracted from the matrixes using acidified water. Simultaneous determination of 22 underivatized amino acids was carried out by a liquid chromatogra...
Article
Full-text available
In this study, analysis of digital color images of fried potato chips were combined with parallel LC-MS based analysis of acrylamide in order to develop a rapid tool for the estimation of acrylamide during processing. Pixels of the fried potato image were classified into three sets based on their Euclidian distances to the representative mean value...
Article
A simple and rapid method was developed and validated for the determination of acrylamide in potato and cereal-based foods by using a single quadrupole liquid chromatography–mass spectrometry (LC–MS) interfaced with positive atmospheric pressure chemical ionization (APCI+). Acrylamide was simply extracted with 0.01 mM acetic acid in a vortex mixer...
Article
A generic sample preparation method for the determination of acrylamide in foods was developed. The method entails extraction with methanol, purification with Carrez I and II solutions, evaporation and solvent change to water, and cleanup with Oasis HLB solid-phase extraction (SPE) cartridge. The final extract was analyzed by liquid chromatography-...
Article
An improved analytical method for the rapid, reliable, and sensitive determination of hydroxymethylfurfural (HMF) in baby foods is described. It entailed aqueous extraction from food matrix with simultaneous clarification using Carrez I and II reagents, solid-phase extraction cleanup using Oasis HLB, and analysis by liquid chromatography-mass spect...
Article
The potential of acrylamide formation and degradation was studied in fructose-asparagine reaction system at different temperatures (120-200 degrees C). Kinetic data for concurrent formation and degradation of acrylamide was analysed based on a simplified form of chemical reaction in series in which acrylamide occurred as an intermediate. Experiment...
Article
Headspace GC-MS has been optimized for the determination of furan in foods. The conditions of sample preparation, headspace sampling and GC separation were optimized to enhance sensitivity during GC-MS analysis. Green coffee was used to prepare a matrix matched calibration curve for furan. However, it was unexpectedly found that a green coffee samp...
Article
A simple and rapid method using liquid chromatography coupled to diode array detection (LC-DAD) was developed for the determination of acrylamide in potato-based foods at low levels. The method entails extraction of acrylamide with methanol, purification with Carrez I and II solutions, evaporation and solvent change to water, and cleanup with a Oas...
Article
The goal of this study was to develop and validate a liquid chromatography (LC) method for the rapid determination of dipyrone (metamizole sodium) in solid and liquid formulations. Samples were extracted with water and filtered prior to LC analysis. The analytical procedure involved reversed phase LC with a Zorbax SB C18 column (5 μm particle size,...
Article
Full-text available
A survey was carried out to determine the co-occurrence of ochratoxin A and aflatoxin B1 in dried figs from Turkey. Samples from two seasons of crops (2003 and 2004) intended for export to the European Union and the 2004 crop obtained from the domestic Turkish market were analyzed. Affinity column cleanup methods were employed for determining separ...
Article
An improved analytical method for the determination of acrylamide in coffee is described using liquid chromatography coupled to mass spectrometric detection (LC-MS). A variety of instant, ground and laboratory roasted coffee samples were analysed using this method. The sample preparation entails extraction of acrylamide with methanol, purification...
Article
A survey of retail Turkish foods was conducted for acrylamide using an in-house validated LC-MS method. The recoveries obtained for a variety of food matrices ranged between 81.2 and 96.8% for a spiking level of 500 ng g(-1). The limit of quantification was determined as 15-20 ng g(-1) depending on the food matrix in the basis of a signal-to-noise...
Article
An interlaboratory study was conducted to evaluate the effectiveness of an immunoaffinity column cleanup liquid chromatography (LC) method for determination of aflatoxin B1 and total aflatoxins in hazelnut paste at European regulatory limits. The test portion was extracted with methanol-water (6 + 4). The extract was filtered, diluted with phosphat...
Article
It has been suggested that the temporal and spatial variability of bioavailable iron delivered to the ocean may be controlled via in-cloud photochemical reduction of desert dust, assisted by the impact of oxalate released by fungi in the desert soil. The basic process in the photochemical production of bioavailable iron through decarboxylation reac...
Article
The temporal and spatial variability of bioavailable iron delivered to the ocean may be controlled via in-cloud photochemical reduction of desert dust, assisted by the impact of oxalate released by fungi in the desert soil. The basic process in the photochemical production of bioavailable iron through decarboxylation reaction involves simultaneous...
Article
A rapid, precise, and specific high-performance liquid chromatographic method is described for the simultaneous determination of paracetamol, phenylephrine HCI, and chlorpheniramine maleate in combined pharmaceutical dosage forms. The method involves the use of a microBondapak CN RP analytical column (125 A, 10 microm, 3.9 x 150 mm) at 22 degrees C...
Article
Full-text available
A post-column derivatization HPLC method with visible absorbance detection at 521 nm was modified for the simultaneous determination of Fe(II) and Fe(III) in mixtures. The method was applied to pharmaceuticals marketed in Turkey. Iron species were separated on a post-column derivatization HPLC, IonPac CS5A (4x250 mm) analytical column using a pyrid...
Article
A rapid and specific proton magnetic resonance spectroscopic method was developed for determining fluconazole in medicaments. 2,4-Dichloro-3,5-dinitrobenzoic acid was used as the internal standard and dmso-d6 served as the NMR solvent. The concentration of drug per unit dose was calculated from the integration values for the resonance signals of fl...
Article
A rapid and specific proton magnetic resonance spectroscopic method was developed for determining acetazolamide in tablets. Maleic acid was used as the internal standard and DMSO-d6 served as the NMR solvent. the concentration of drug per unit dose was calculated from the integration values for the resonance signals of acetazolamide at 2.14 ppm and...
Article
Full-text available
The development of a sensitive automated method for residue control of oxytetracycline (OTC) in cured meat (soudjouk) is described. The principle steps involve the extraction of OTC from cured meat in the presence of citric acid with nitric acid, methanol and de-ionized water, and then the determination by HPLC. In HPLC, Hypersil BDC C18 column was...
Article
The development of a sensitive automated method for residue control of oxytetracycline (OTC) in cured meat (soudjouk) is described. The principle steps involve the extraction of OTC from cured meat in the presence of citric acid with nitric acid, methanol and de-ionized water, and then the determination Ly HPLC. In HPLC, Hypersil BDC C18 column Nas...

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