Hamed Avari

Abbott Laboratories | AMO · Cardiovascular

Objective It is unclear whether supplemental oxygen and noninvasive ventilation respiratory support devices increase the dispersion of potentially infectious bioaerosols in a pressurized air medical cabin. This study quantitatively compared particle dispersion from respiratory support modalities in an air medical cabin during flight. Methods Dispe...

COVID-19 patients with respiratory distress require additional oxygen support. Some of the respiratory support devices used in intensive care units could increase the dispersion of infectious viral particles placing healthcare workers at increased risk of infection. The goal was to compare viral aerosol dispersion from invasive and non-invasive res...

Rationale: Patients with severe COVID-19 require supplemental oxygen and ventilatory support. It is unclear whether some respiratory support devices may increase the dispersion of infectious bioaerosols and thereby place healthcare workers at increased risk of infection with SARS-CoV-2. Objectives: To quantitatively compare viral dispersion from...

Purpose: Atrial fibrillation (AF) is the most common heart rhythm disorder in the world. Radiofrequency catheter ablation (RFCA) has become the preferred method of treatment for drug-refractory AF. One of the rare (< 0.2%) but deadly (≈ 80%) complications of RFCA is Atrioesophageal fistula (AEF). Although the exact pathophysiological events in dev...

Cardiovascular diseases (CVDs) are the number one cause of death globally. Arterial endothelial cell (EC) dysfunction plays a key role in many of these CVDs, such as atherosclerosis. Blood flow-induced wall shear stress (WSS), among many other pathophysiological factors, is known to significantly contribute to EC dysfunction. The present study repo...

The parallel plate flow chamber (PPFC) has gained popularity due to its applications in fields such as biological tissue engineering. However, most of the studies using PPFC refer to theoretical relations for estimating the wall shear stress (WSS) and, hence, the accuracy of such quantifications remains elusive for anything other than steady lamina...

Numerous in vitro systems have previously been developed and employed for studying the effects of hemodynamics on endothelial cell (EC) dysfunction. In the majority of that work, accurate flow quantification (e.g., uniformity of the flow over the ECs) remains elusive and wall shear stress (WSS) quantifications are determined using theoretical relat...

Most of the studies using Parallel plate flow chambers (PPFC), have relied on theoretical relations for estimating the wall shear stress (WSS) for steady flow only. In the current study, a laser Doppler velocimetry (LDV) method was used to quantify the flow in a PPFC (H = 1.8 mm × W = 17.5 mm, D h = 3.26 mm, aspect ratio 9.72) under steady and lami...

Endothelial Cell (EC) dysfunction due to hemodynamic factors has been the subject of study for almost four decades. Numerous in vitro systems have been developed and employed for studying the effects of hemodynamics on EC dysfunction. The current work presents a novel hemodynamic system with live microscopy system for studying the effects of quanti...

Adjusting the rhythm of breath is one of the important parameters that a successful athlete must consider. In this paper, the relationship between man's activity and respiration rhythm is studied. A numerical simulation is carried out on a 2D axi-symmetric model using computational fluid dynamics (CFD) method. The model considers the oxygen uptake...