Halina Binde Doria

Halina Binde Doria
Senckenberg Biodiversität und Klima - Forschungszentrum | BiK-F · Center for Translational Biodiversity Genomics (LOEWE-TBG)

Dr.

About

21
Publications
4,166
Reads
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543
Citations
Introduction
Experience in the area of Aquatic Ecotoxicology and Risk Assessment using fish, insects and crustacean as bioindicators.
Additional affiliations
March 2014 - February 2018
Federal University of Paraná
Position
  • PhD Student
Description
  • Existence of circadian rhythms in antioxidant enzymes in zebrafish (Danio rerio) and its disruption by exposure to copper
March 2017 - February 2018
Karlsruhe Institute of Technology
Position
  • PhD Student
January 2009 - February 2012
Federal University of Paraná
Position
  • Student
Description
  • Integrated assessment of morphological, biochemical, physiological, genetic, immunological and behavioral biomarkers. In order to assist public policies of water quality and establish a water quality criteria for the preservation of aquatic biota.
Education
March 2014 - March 2018
Federal University of Paraná
Field of study
  • Molecular and Cell Biology
April 2012 - April 2014
Federal University of Paraná
Field of study
  • Molecular and Cell Biology
February 2007 - December 2011
Federal University of Paraná
Field of study
  • Biological Sciences

Publications

Publications (21)
Article
From the concentration in water and sediments, bioconcentration and bioaccumulation of copper (Cu), manganese (Mn), zinc (Zn), iron (Fe), cobalt (Co), cadmium (Cd), chrome (Cr), silver (Ag), lead (Pb), nickel (Ni), aluminum (Al), and arsenic (As) were determined in the gills, liver, and muscles of Geophagus brasiliensis in the Alagados Reservoir, P...
Preprint
Full-text available
The emission of artificial light at night (ALAN) is rapidly increasing worldwide. Yet, evidence for its detrimental effects on various species is accumulating. While the effects of ALAN on phenotypic traits have been widely investigated, effects on the molecular level are less well understood. Here we aimed to integrate the effects of ALAN at the t...
Article
Full-text available
Mutations are the ultimate source of heritable variation and therefore the fuel for evolution, but direct estimates of mutation rates exist only for few species. We estimated the spontaneous single nucleotide mutation rate among clonal generations in the waterflea Daphnia galeata with a short-term mutation accumulation approach. Individuals from ei...
Article
Susceptibility to hazardous materials and contamination is largely determined by genetic make-up and evolutionary history of affected organisms. Yet evolutionary adaptation and microevolutionary processes triggered by contaminants are rarely considered in ecotoxicology. Using an evolve and resequencing approach, we investigated genome-wide response...
Article
Most organisms respond and can adapt to photoperiodic changes. This affects measurable end points like developmental time, survival and fertility. For ectotherms like Chironomus riparius, temperature is the most studied environmental cue regulating their life cycle, whereas photoperiodic influence is neglected. However, the developmental speed betw...
Article
Evolutionary adaptation and phenotypic plasticity are important processes on how organisms respond to pollutant exposure. We dissected here the contribution of both processes to increased tolerance in Chironomus riparius to cadmium (Cd) exposure in a multi-generation experiment and inferred the underlying genomic basis. We simulated environmentally...
Preprint
Full-text available
Evolutionary processes and acquired tolerance to toxicants are important factors governing how animals respond to chemical exposure. Evidence for increased tolerance to cadmium (Cd), a widely distributed toxic metal in aquatic environments, in Chironomus riparius is conflicting and still questioned if it happens through phenotypic plasticity or gen...
Article
Copper (Cu) is an essential metal utilized in aquaculture activities for both nutritional and disease control. Conversely, this metal can present a risk of exposure to biota depending on the used concentration, but data are still scarce and studies to establish the real risk of copper exposure to fish even in aquaculture activities are welcome. To...
Article
Existing mutagenicity tests for metazoans lack the direct observation of enhanced germline mutation rates after exposure to anthropogenic substances, therefore being inefficient. Cadmium (Cd) is a metal described as a mutagen in mammalian cells and listed as a group 1 carcinogenic and mutagenic substance. But Cd mutagenesis mechanism is not yet cle...
Preprint
Existing mutagenicity tests for metazoans lack the direct observation of enhanced germline mutation rates after exposure to anthropogenic substances, therefore being inefficient. Cadmium (Cd) is a metal described as a mutagen in mammalian cells and listed as a group 1 carcinogenic and mutagenic substance. But Cd mutagenesis mechanism is not yet cle...
Preprint
Full-text available
Mutations are the ultimate source of heritable variation and therefore the fuel for evolution, but direct 16 estimates exist only for few species. We estimated the spontaneous nucleotide mutation rate among 17 clonal generations in the waterflea Daphnia galeata with a short term mutation accumulation 18 approach. Individuals from eighteen mutation...
Article
Cadmium (Cd) is a non-essential highly toxic metal and its presence in the environment has been a concern over the years. On the present study we adopt the spiked water exposure scenario to study early Cd contamination across five generations of the model organism Chironomus riparius. Animals were, at the beginning of each generation, submitted to...
Article
The circadian clock is a key cellular timing system that coordinates physiology and behavior. Light is a key regulator of the clock mechanism via its activation of Per and Cry clock gene expression. Evidence points to a key role of reactive oxygen species (ROS) in resetting this process. In this context, the aim of the present study was to explore...
Article
The present study evaluated if ZnONPs induce oxidative stress, immunological impairment and cellular damage in tilapia (Oreochromis niloticus), as well as the possible protective effect of vitamin E. Fish were fed for ten days and five study groups were investigated: controls, two ZnONPs concentrations (1.5 and 2.5 mg.L-1) and 1.5 and 2.5 mg.L-1 of...
Article
Full-text available
Vossoroca is a reservoir in the Brazilian state of Paraná. Although it is located near big cities and can be used as a human water supply, it has remained unstudied. Concentrations of toxic metals and arsenic in sediments, water, liver, gills, and muscle of Geophagus brasiliensis from the reservoir were analyzed using atomic absorption spectrometry...
Article
Full-text available
The Alagados Reservoir located in the Brazilian city of Ponta Grossa is used to supply water for human consumption but is impacted by toxic metals. The current study combined chemical, biochemical, and multivariate analyses to determine the bioavailability of toxic metals at three sites (AL-A, AL-B, and AL-C) within the Alagados Reservoir. Metal bi...
Article
Full-text available
The Iguaçu River, located at the Southern part of Brazil, has a great socioeconomic and environmental importance due to its high endemic fish fauna and its potential to generate hydroelectric power. However, Iguaçu River suffers intense discharge of pollutants in the origin of the river. In a previous report, the local environmental agency describe...

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