Halim Issever

Halim Issever
Istanbul University · Department of Public Health (Istanbul Medical Faculty)

Doctor of Philosophy

About

225
Publications
49,547
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
4,419
Citations
Additional affiliations
January 1996 - July 2015
Istanbul University
Position
  • Researcher

Publications

Publications (225)
Article
Introduction: Telemedicine is a follow-up system that can improve the quality of management and cost-effectiveness of rapidly increasing diabetes patients. Methods: Two hundred adult patients with diabetes were enrolled in this prospective, randomized study. Consecutive patients were divided equally into two groups. Both groups received routine car...
Article
Full-text available
GENETIC POLYMORPHISMS IN 15 STR LOCI IN THE TURKISH POPULATION LIVING IN ISTANBUL PROVINCE
Article
Background: Although paucigranulocytic asthma (PGA) is the most common phenotype of stable asthma, its features have not been adequately studied. In this study, we aimed to display the characteristics of PGA. Method: A total of 116 non-smoking adult patients with asthma (80% women; mean ± standard deviation age, 39 ± 12.9 years) admitted to three t...
Article
Full-text available
Background: This cross-sectional study evaluated the utility of the 2018 European Federation of Periodontology/American Academy of Periodontology (EFP/AAP) classifications of epidemiological studies in terms of periodontitis severity, prevalence and associated risk factors and the 2012 American Academy of Periodontology/Centers for Disease Control...
Article
Objective: The work accidents are one of the biggest issues of today’s occupational lives regarding the human losts and eco- nomical losts. The humanity lost of this daily issue is pretty huge. Material and Method: At this study, it is aimed to compare the EU’s work accidents resulted with death and SSI Statistical Year- book datas standardized num...
Article
Full-text available
Chronic lymphocytic leukemia (CLL) is a neoplasm characterized by excessive accumulation of B lymphocytes in the peripheral blood, bone marrow and lymph nodes. We assessed the expressions of 22 genes in the p53 pathway in 30 CLL patients and 15 healthy subjects by a RT2 Profiler PCR (polymerase chain reaction) Array technique and their relation to...
Article
Objective: The aim of this study was to compare the clinical and immunological results of nonsurgical periodontal treatment with or without the erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser. Background data: As lasers have begun to be used in dentistry, the Er,Cr:YSGG laser has started to attract attention in the field of per...
Article
To compare the efficacy of intermittent and consecutive balneological outpatient treatment (hydrotherapy and peloidotherapy) in fibromyalgia syndrome (FMS). A parallel 1:1, single-blind, pilot study was performed. Patients were recruited from musculoskeletal disorders outpatient clinic. Eligible participants were patients aged 18–60, diagnosed as F...
Chapter
Introduction: Metal workers are under the risk of musculoskeletal disorders because of great physical efforts are required. Objective: To determine the prevalence and physical risk factors of MSD among metal workers. Methods: The study has been done in metal industry factories at Istanbul and nearby. 1000 questionnaires sent, only 130 of them ret...
Article
Full-text available
zet Amaç: Tanımlayıcı ve ilişki arayıcı tipteki bu araştırma hemşirelerde iş güvenliğini bazı değişkenler yönünden incelemek amacı ile yapıldı. Materyal-Metot: Araştırmanın örneklemini bir üniversitenin farklı iki hastanesinde çalışan ve araştırmaya istekli ve gönüllü olan toplam 1072 hemşire oluşturdu. Araştırmanın verileri "Hemşire Bilgi Formu ve...
Article
Introduction The effect of spa therapy, a non-pharmacological treatment for chronic low back pain (CLBP) has been evaluated by several randomized clinical trials. This randomized controlled trial was conducted to compare the effect of balneotherapy alone versus balneotherapy with physical exercise. Methods Participants (n = 60) with low back pain...
Article
Full-text available
Backround & aims: To evaluate Turkey according to the number of work accidents, occupational diseases and related mortality rates, insured workers, establishments and cities, which are important issues in terms of showing countries' situation. Materials & methods: The data of 2010-2015 years according to the numbers of insured labourers and workpla...
Article
Background Intensive care units (ICUs) are noisy environments, which may have negative psychological effects on nurses. Aims and objectives To investigate the effects of the noise level of ICUs on nurses' burnout, job satisfaction, anxiety, psychological symptoms and general psychopathology level. Design A descriptive and correlational study. Me...
Article
Full-text available
Time series analysis of the admission to emergency department Time series analysis of the admission to the emergency department due to respiratory and cardiovascular diseases between Abstract Aim: The aim of this study was to estimate the admissions to the emergency department due to cardiovascular and/or respiratory diseases for the next twelve mo...
Poster
Full-text available
Avrupa Birliği’ne (AB) üyelik sürecindeki ülkemizin, iş kazaları-meslek hastalıkları ve bunlara bağlı ölüm hızlarının AB ülkeleriyle ne derece benzer olduğu önemlidir. Bu çalışmada SGK 2010-2015 İstatistik Yıllığı verileriyle “iş kollarındaki” iş kazası, meslek hastalıkları ve ölüm hızlarının; sigortalı işçi sayısına göre standardize edilerek değer...
Poster
Full-text available
Amaç: Ülkelerin durumunu göstermesi bakımından önemli konulardan olan iş kazaları, meslek hastalıkları ve buna bağlı ölüm hızları verilerini; Türkiye’de sigortalı işçiler ve işyerleri sayısına göre şehirler bazında değerlendirmeyi amaçladık. Gereç ve Yöntem: 2010-2015 yılları arasında, Türkiye Cumhuriyeti (T.C.) Sosya lGüvenlik Kurumu (SGK) istati...
Article
Objective: The aims of this study are to evaluate if occlusal types affect the type of temporomandibular disorders and if the onset of complaints are related to the type of internal derangements. Methods: One hundred thirty-four patients were evaluated. Occlusion types were grouped as Angle Class I, II, and III. The temporomandibular disorders w...
Article
Alzheimer's disease (AD) is a neurodegenerative disease and is identified by the detection of amyloid-plaques and neurofibrillary tangles in the brain. Amyloid precursor protein gene, presenilin 1 (PSEN1) gene, and presenilin 2 (PSEN2) gene are responsible for this disease. PSEN2 and amyloid precursor protein (APP) gene mutations are a much rarer c...
Article
Full-text available
Background: Endovascular treatment of symptomatic peripheral artery disease has gained widespread acceptance. The efficacy and safety of drug coated balloon angioplasty in the setting of critical limb ischemia in comparison to conventional surgery has not been demonstrated. We have compared our results with DCB angioplasty to conventional bypass s...
Article
Full-text available
Objective: To assess the incidence of type 1 diabetes mellitus (T1DM) in children under 18 years of age in the northwest region of Turkey during 2013-2015. Methods: All newly diagnosed T1DM cases were recorded prospectively during 2013-2015. Total as well as gender and age group specific (0-4, 5-9, 10-14 and 15-17 age) mean incidences per 100.00...
Article
Objective Parathyroid hormone (PTH) enhances bone healing. Strontium ranelate (SR) is an antiresorptive agent that increases bone formation. Reports about combined effects of PTH and SR on local bone regeneration in osteoporotic subjects are limited. We aimed at investigating the efficacy of PTH and SR for promoting new bone formation in critical s...
Poster
Full-text available
Backround & aims: To evaluate Turkey according to the number of work accidents, occupational diseases and related mortality rates, insured workers, establishments and cities, which are important issues in terms of showing countries' situation. Materials & methods: The data of 2010-2015 years according to the numbers of insured labourers and workpla...
Presentation
Full-text available
Avrupa Birliği’ne (AB) üyelik sürecindeki ülkemizin, iş kazaları-meslek hastalıkları ve bunlara bağlı ölüm hızlarının AB ülkeleriyle ne derece benzer olduğu önemlidir. Bu çalışmada SGK 2010-2015 İstatistik Yıllığı verileriyle “iş kollarındaki” iş kazası, meslek hastalıkları ve ölüm hızlarının; sigortalı işçi sayısına göre standardize edilerek değer...
Article
Background: Studies on real-life adherence to subcutaneous allergen immunotherapy (SCIT) for respiratory allergy are scarce. The aim of this study was to evaluate adherence to SCIT. Methods: The patients prescribed SCIT for allergic rhinitis and/or asthma in 2009-2011 were contacted in 2014 and asked whether they completed at least the 3 years o...
Poster
This study aimed to investigate whether the irritants used in bread and plastic industry cause irritation in the respiratory tract to determine the benefits of adding FeNO measurement method to periodical controls in various business branches. Our cross-sectional study was carried out 88 workers in the plastics and bread sectors in Istanbul. Our co...
Article
Full-text available
Pulmonary hypertension (PH) is a fatal disease although significant improvements in treatment are achieved. Easily implemented and noninvasive prognostic techniques are needed while following-up these patients. The aim was to investigate the role of fractional exhaled nitric oxide (FeNO) in follow-up for patients with PH. In this longitudinal study...
Article
Objective: In this split-mouth clinical trial, we evaluated the clinical benefits of low-level laser therapy (LLLT) as an adjunct to nonsurgical periodontal treatment in patients with type 2 diabetes mellitus (DM). Background data: The impaired wound healing seen in diabetic patients may affect the results of periodontal treatment and may requir...
Article
Full-text available
Objective To determine the citizenship behavioural dimension exhibited by nurses working in public hospitals and to assess the behaviours shown based on personal characteristics of the employees. Material and method 291 nurses working in Northern Region Public Hospitals were included within scope of the study. A form composed of the criteria measu...
Article
Introduction: Pulmonary hypertension (PH) is a chronic, progressive disease with a high morbidity and mortality. Its pathobiology involves interacting pathways of prostacyclin (PGI2), endothelin, and nitric oxide (NO). There are few studies which evaluated exhale NO levels in patients with PH. Aim of this study was to investigate the levels of exha...
Article
Full-text available
Objective: To determine the citizenship behavioral dimension exhibited by nurses working in public hospitals and to assess the behaviors shown based on personal characteristics of the employees. Material and Method: Two hundred ninty-one nurses working in Northern Region Public Hospitals were included within scope of the study. A form composed of t...
Article
Amac: Bu calisma ile ilaclama calisanlarinda solunum fonksiyonlarinin yasam kalitesi uzerine etkisinin incelenmesi amaclanmistir. Gerec ve Yontem: Tum calisanlarin sistemik fizik muayeneleri yapilmis ve solunum fonksiyon testlerine bakilmistir. Astim yonunden sorgulamalari NIOSH astim sorgulama formu ile yapilmis ve yasam kalitesi, Kisa Form-12 (Sh...
Article
Introduction: Patients with pulmonary hypertension (PH) show no symptoms at rest, but symptoms are triggered by physical activities. Objectives: The primary aim of our study was to assess physical activity of patients with PH by using an activity monitor. The secondary aim was to evaluate the correlation between the activity monitor parameters a...
Article
Full-text available
Introduction: Conflicting results has been achieved in a small number of clinical studies evaluating the efficiency of magnesium sulphate (MS) in COPD exacerbations. We aimed to investigate the efficiency of nebulised MS in COPD exacerbations. Patients and methods: Twenty patients who met the study criteria were randomized into two groups. All p...
Article
Objective: We aimed to investigate the role of autoimmunity in the etiopathogenesis of alopecia areata (AA) and the effects of the coexisting autoimmune diseases on the prognosis of AA. Methods: The records of 134 AA patients diagnosed in the dermatology and venereology outpatient clinic were retrospectively analyzed for the history of concomitant...
Article
Full-text available
Objective: Analyzing mortality rates and the reasons for these in Turkey’s urban allocations using geographic information systems (GISs) is a new research area. While planning health services, knowing the mortality rates and reasons according to age and residential area are a big source of information for health planners and people who provide heal...
Article
Full-text available
Fasting plasma glucose (FPG) and hemoglobin A1c (HbA1c) have been used to diagnose new-onset diabetes mellitus (DM) in order to simplify the diagnostic tests compared with the 2-hour oral glucose tolerance test (OGTT; 2-hPG). We aimed to identify optimal cut-off points of high sensitive C-reactive protein (hs-CRP) in new-onset DM people based on FP...
Article
Full-text available
Purpose: To evaluate the effect of hormone replacement therapy(HRT) on periodontal treatment outcomes in a group of postmenopausal women with periodontitis. Materials and Methods: 23 post-menopausal chronic periodontitis patients were included in this study. The test group(n=11) consisted of women who started HRT with this study and received conjug...
Article
Full-text available
Background Essential micronutrients are important for maintenance of life. Deficiency of micronutrients is more likely to be encountered in children, and women studies are required to investigate the status of micronutrients in children and women. This study aimed to longitudinally evaluate changes in zinc, copper, and iron levels in breastfed infa...
Article
Patent vascular access is critical for patients on regular hemodialysis. Prosthetic grafts are good alternatives when the superficial venous system is of poor quality. However, thrombosis is one of the main drawbacks of synthetic grafts, with reports of 59% to 90% patency rates for 1 year. In cases of thrombotic occlusion of prosthetic arteriovenou...
Article
Full-text available
The objective of this study was to determine the phenotypic profile of blood mononuclear cells, specifically CD8+/CD28+ cells, in patients with generalized aggressive periodontitis (GAgP) and chronic periodontitis (CP) in peripheral blood and in blood obtained from periodontal defect site which might contribute to tissue damage. 13 GAgP, 11 chronic...
Article
Full-text available
Background and Design: Alopecia areata (AA) is characterized by non-scatricial hair loss with exacerbations and remissions. Although its etiopathogenesis is not known, autoimmune factors have been suggested. Our aim was to make contribution to the epidemiological properties of AA in Turkey, and to determine the bad prognostic factors that affect th...
Article
Full-text available
Generalized aggressive periodontitis (GAgP) is a complex periodontal disease affecting the entire dentition with a rapid destruction of the periodontium and resulting in loss of teeth. We hypothesized that better clinical healing of adjunctive use of amoxicillin plus metronidazole combination may be related to the effect of this combination therapy...
Article
Full-text available
There are scarce data about the prevalence of Hymenoptera venom allergy in the general population. The aim of this study was to determine the prevalence of Hymenoptera venom allergy in the general adult population of Istanbul. A total of 17,064 randomly selected telephone numbers were contacted and 11,816 (69.25%) individuals who agreed to particip...
Article
Full-text available
The aim of this study was to investigate the role of transglutaminase 2(TG2) in renal cell carcinoma (RCC) by comparing the immunohistochemistry staining of primary and metastatic tumor tissues. A total of 33 metastatic RCC(mRCC) and 33 non-metastatic RCC (nmRCC) patients who were matched as closely as possible based on gender, age, nuclear grade a...
Article
Full-text available
Purpose: Hemostatic agents may be used topically to control hemorrhage, especially in patients with bleeding disorders. The agent used may have a negative effect on the tissue prolonging the healing time. The aim of this study was to compare the effects of 3 different hemostatic agents on fibroblast cells on a rat primary fibroblast cell culture m...
Article
Full-text available
Background: Since the 1970s, MORA bioresonance therapy has globally been applied in the context of complementary medicine for various indications. In this regard, practitioners also report successful application in smoking cessation. The present study aims to verify these reports in a controlled study setting. Methods: In order to achieve the af...
Article
Purpose: The aim of this study was to evaluate the distance between the roots of the impacted third molars and the floor of the mouth to predict the risk of lingual root displacement during surgery. Materials and methods: Thirty-one patients (5 men and 26 women) were evaluated for this study using cone-beam computed tomography (CBCT). The teeth...
Article
Full-text available
Objective: The aims of this descriptive, cross-sectional investigation were to evaluate the gingival health awareness of dental students by comparing their clinical gingival bleeding scores and self-reports, and to compare differences in awareness between males and females. Methods: In total, 100 (51 males, 49 females) freshman dental students wer...
Article
Full-text available
Introduction: Although epidemiological studies have reported an association between smoking and increases in tuberculosis, the relationship between indoor air pollution and risk of tuberculosis is not fully understood. A limited number of studies have suggested that smoking and indoor air pollution may play a role in the pathogenesis of tuberculos...
Article
Full-text available
Background: This study aims to investigate the prevalence and incidence of venous thromboembolism in intensive care unit (ICU) patients receiving thromboprophylaxis. Methods: Seventy-four consecutive patients (34 females, 40 males; mean age 55.8±19.4 years; range 20-86 years) admitted to the medical-surgical ICU, who were ≥18 years old and expecte...
Article
Problem-oriented learning is an effective method of learning that increases students' learning motivation, improves the relationship amongst students and results in open-minded discussions. In this study, a new problem-oriented pharmacobiochemistry course related to 'oxidative metabolism of drugs by cytochrome P450 (CYP450) systems' was designed. S...
Article
Full-text available
Objective: Propofol has been accused for increasing plasma lipid levels during continuous infusion due to its lipid content. We aimed to show the effect and the risk of propofol infusion on plasma lipid and glucose levels in patients with hyperlipidemia undergoing coronary artery bypass graft surgery (CABG), and to compare them with a midazolam use...
Article
Objective: Cytokines that are released from activated lymphocytes, monocytes, and macrophages modify the intensity of immune inflammatory responses. Differences in cytokine production are due to sequence variants in cytokine genes. Cytokines are involved in all biological processes related to cell growth, cell differentiation, inflammation, and imm...
Article
Full-text available
Objective: To investigate the effects of inspiratory and expiratory muscle training on pulmonary functions in patients with slowly progressive neuromuscular disease. Design: Prospective randomized controlled double-blinded study. Setting: Chest diseases clinic of university hospital. Subjects: Twenty-six patients with slowly progressive neur...