Hale Z Batur Caglayan

Gazi University · Department of Neurology

INTRODUCTION: This study aimed to assess the diagnostic and prognostic value of red cell distribution width (RDW)which is an easily accesible parameter obtained from complete blood count in patients with cerebral venous thrombosis (CVT) in a single tertiary center. METHODS: Medical records of 69 patients with cerebral venous thrombosis who were fol...

Background: Patients with cerebellar ischemic stroke may be misdiagnosed and may exhibit a delayed time to acute stroke treatment compared with patients with anterior circulation ischemic stroke. The posterior circulation Alberta stroke program early computed tomography score (pc-ASPECT) score has been used to evaluate hyperacute stroke, much as t...

GİRİŞ ve AMAÇ: Türkiye'de yatarak tedavi gören akut inme hastalarının profiline ilişkin nesnel veriler sınırlıdır. Ancak bu, bölgesel akut inme yönetimi de dâhil olmak üzere ilgili sağlık sisteminin optimize edilmesi için gereklidir. NöroTek çalışması, temel hastane içi kalite ölçütleri perspektifinde iskemik inme, intraserebral kanama ve kardiyopu...

Background: Limits of stability (LOS) is a major component of balance dysfunction in people with multiple sclerosis (MS). The functional reach test (FRT) is a clinical LOS assessment; however, its psychometric properties have not been investigated in people with MS yet. Objectives: To investigate: (1) the intrarater, interrater, and test–retest rel...

The prevalence of headache in stroke has been reported between 8% and 34%. Determining the prevalence, features, and effects on prognosis of cerebellar ischemic strokes that presented with headache solely and/or with other cerebellar signs were the aims of our study. All patients diagnosed with cerebellar ischemia were included. Electronic medical...

INTRODUCTION: Recent studies have highlighted that most strokes can possibly be prevented by risk factor modification and lifestyle changes. Female gender and lower educational level are two critical sociodemographic factors that are related to increased stroke risk. In this study, we investigated the interplay between these two features,which are...

Introduction: Cerebral venous and sinus thrombosis (CVST) may lead to cerebral edema and increased intracranial pressure; besides, ischemic or hemorrhagic lesions may develop. Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the cerebral hemorrhage (CH) group and the CVST group. M...

Introduction: Cerebral venous and sinus thrombosis (CVST) may lead to cerebral edema and increased intracranial pressure; besides, ischemic or hemorrhagic lesions may develop. Intracerebral hemorrhages occur in approximately one-third of CVST patients. We assessed and compared the findings of the cerebral hemorrhage (CH) group and the CVST group....

INTRODUCTION: Modifiable risk factors constitute approximately 90% of the cumulative risk factor burden in stroke. One out of 4 strokes were preventable by optimization of these vascular risk factors according to Fisher's preventable stroke score (FPSS). However, the threshold values and coding criteria of the score are outdated. The "Life's Simple...

Background: Early diagnosis of cerebral venous sinus thrombosis (CVST) associated with reproductive health-related risk factors (RHRF) including pregnancy, puerperium, and oral contraceptive (OC) use can prevent severe neurological sequelae; thus, the symptoms must be documented in detail for each group. Methods: Out of 1144 patients with CVST,...

Background Unhealthy lifestyle and inadequate control of vascular risk factors are the major contributors of stroke burden. Failure in achieving the target levels in control of these factors, not only designate missed opportunities contributing to the preventability of an incident stroke, but also set the post-stroke treatment goals in a case wise...

Purpose The aim of this study is to evaluate the presence and prognostic impact of early seizures in cerebral venous sinus thrombosis patients (CVST). Method VENOST is a retrospective and prospective national multicenter observational study. CVST patients with or without epileptic seizures (ES) were analyzed and compared in terms of demographic an...

Background: Headache is the most common complaint in cerebral venous sinus thrombosis (CVST) and it may sometimes be the only symptom found in patients presenting with CVST. In this retrospective and prospective study, we investigated whether there are any differences in terms of clinical risk factors, radiology and prognosis in cases with CVST tha...

Objective: Recent evidence suggests that insulin resistance may play an important role in the pathogenesis of Alzheimer's disease (AD). In this study, the probable role of insulin resistance in the pathogenesis of AD was investigated in patients with Type 2 Diabetes Mellitus (T2DM). Methods: Serum amyloid beta (Aβ) (1-42), insulin like growth fa...

Aim: Systemic lupus erythematosus (SLE) is an unusual risk factor for cerebral venous sinus thrombosis (CVST). As few CVST patients with SLE have been reported, little is known regarding its frequency as an underlying etiology, clinical characteristics, or long-term outcome. We evaluated a large cohort of CVST patients with SLE in a multicenter stu...

Background and Aims: Atrial fibrillation (AF) is the most common cause of cardioembolic stroke. Although it is well established that anticoagulant therapy is the treatment of choice for stroke prevention in high-risk AF patients, a significant proportion of AF patients suffer from ischemic stroke while not being optimally anticoagulated. Herein, we...

Background and Aims: Diabetes mellitus is a major modifiable risk factor for ischemic stroke. Impaired glycemic control at the time of admission is known to be associated with unfavorable outcome. In this study, we assessed factors that were related to disturbed blood glucose regulation prior to stroke among patients admitted with ischemic stroke....

Background and Aims: It is considered that 90% of strokes are preventable by vascular risk factor (RF) control.We analyzed the distribution of uncontrolled RF burden among various ischemic stroke subtypes and determined the contribution of anti-thrombotic therapy on this interplay. Methods: Information about presence and optimal control of 7 major...

Background: This study aimed to identify the reversibility of MRI findings indicative of increased intracranial hypertension in idiopathic intracranial hypertension (IIH) patients after treatment. Methods: This retrospective, observational study included demographic and clinical data from 10 patients with IIH and 10 controls. Brain MRI findings...

Objective: To determine the etiologic factors and clinical profile of isolated third, fourth, and sixth nerve palsies in neuro-ophthalmology outpatient clinics of two different reference centers. Materials and Methods: Retrospective evaluation of medical records from the institutional database. Results: A total of 127 (78 male, 49 female) patients...

Background/aim: Following stroke, damage to the central nervous system and adaptive changes in muscle tissue are factors responsible for the loss of muscle strength. Even though it is suggested that early physiotherapy and mobilization prevent structural adaptive changes in muscle tissue, studies regarding this issue are insufficient. The aim of t...

Objective This study was performed to determine the rate of cerebral venous sinus thrombosis (CVST) among cases of Behçet's disease (BD) included in a multicentre study of cerebral venous sinus thrombosis (VENOST). Methods VENOST was a retrospective and prospective national multicentre observational study that included 1144 patients with CVST. The...

Traditional, complementary, and alternative medicine practices are used in the prevention, diagnosis, and treatment of a wide variety of diseases in the world. Such practices in Turkey are regulated by the “Regulation of Traditional and Complementary Medicine Practice” issued by the Ministry of Health in the Official Gazette of the Republic of Turk...

Introduction The present study seeks to use transcranial Doppler ultrasound to evaluate cerebral blood flow velocities in anterior and posterior circulation arteries, during an attack-free episode in migraine patients, with and without aura, as well as in chronic tension-type headache patients who were not receiving prophylactic medication. Method...

Objective: This prospective observational study aimed to identify the effects of labor on cerebral hemodynamics by measuring the middle cerebral artery (MCA) blood flow velocity by transcranial Doppler ultrasound (TCD), and the related factors just before delivery and within the 24 h after delivery. Methods: The study included 35 healthy pregnant w...

Background: Pilates is an exercise method which increases strength and endurance of core muscles and improves flexibility, dynamic postural control and balance. Objective: To analyze and compare the effects of Mat and Reformer Pilates methods in Patients with Multiple Sclerosis (MS). Methods: 38 patients with MS were included in the study. Par...

Motor cortex activity level is a critical part of the effect of transcranial direct current stimulation (tDCS) on corticomotor excitability. Based on homeostatic plasticity, the state of the stimulated cortical area influences the direction of neuroplastic changes induced by stimuli. Owing to homeostatic plasticity, cathodal tDCS (c-tDCS) would lik...

Background Based on a number of small observational studies, cerebral venous sinus thrombosis has diverse clinical and imaging features, risk factors, and variable outcome. In a large, multicenter cerebral venous thrombosis (VENOST) study, we sought to more precisely characterize the clinical characteristics of Caucasian patients. Methods All data...

Objective The aim of the present study was to investigate the prevalence and pattern of cognitive dysfunction observed in primary Sjögren's syndrome (PSS) and to examine the relationships between cognitive abilities, depression, fatigue, and quality of life. Materials and Methods Thirty‐two subjects with PSS were compared with 19 healthy controls...

Introduction Previous studies have shown that olfactory functioning is affected by multiple sclerosis (MS). This study assessed the level of the olfactory impairment in early MS by using the Sniffin’ Sticks Test. Methods This study included 30 patients with MS and 30 healthy controls. We collected demographic and clinical data from participants an...

Hale Z Batur Caglayan,1 Ceyla Irkec,1 Bijen Nazliel,1 Aslı Akyol Gurses,2 Irem Capraz11Department of Neurology, Faculty of Medicine, Gazi University, Ankara, 2Department of Neurology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey Introduction: Previous studies have shown that olfactory functioning is affected by multiple sc...

The effects of fatigue on functioning and quality of life in patients with Multiple Sclerosis

Erratum in Lancet. 2015 Feb 14;385(9968):606. Abstract BACKGROUND: High blood pressure is associated with poor outcome after stroke. Whether blood pressure should be lowered early after stroke, and whether to continue or temporarily withdraw existing antihypertensive drugs, is not known. We assessed outcomes after stroke in patients given drugs to...

PurposeTo compare both retinal nerve fiber layer thickness and orbital color Doppler ultrasonography parameters in patients with multiple sclerosis (MS) versus healthy controls.Methods This is an observational case-control study. Forty eyes from MS patients and twenty eyes from healthy volunteers were examined. Eyes were classified into three group...

OBJECTIVE: In Turkey, a national program is governed by National Board of Medical Specialties(BMS), Commision of Syllabus Creation and Standardization to improve and standardize residency training. In the present study, we aimed to assess neurology residency training programs and working conditions in Turkey based on a national survey among residen...

A 47-year-old female with a prior history of POEMS (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes) syndrome was admitted with transient ischemic attacks complicated by dysarthria and right-sided hemiparesis. A blood survey indicated thrombocytosis and hyperfibrinogenemia while imaging of intracranial vasculat...

Susac's syndrome is an uncommon neurologic disorder of unknown cause. It has been described as a clinical triad of encephalopathy, hearing loss, and branch retinal artery occlusions. Clinically the diagnosis is difficult when the patient presents only a portion of a triad. We present a case with vision loss and sensorineural deafness and who had be...

Metabolic disease affect all systems in the body, including the peripheral nervous system, but there is a controversy as whether to consider hyperlipidemia is a cause of peripheral neuropathy. The aim of the present study was to evaluate whether hyperlipidemic subjects with no clinical symptom or sign of peripheral neuropathy showed nerve conductio...

Dilated pupil is a diagnostic challenge encountered by neurologists and ophthalmologists. The aim of this review is to provide an overview of the current data and guidelines concerning dilated pupils. The majority of recent reports on dilated pupils are indicative of several medical conditions that require evaluation. The topical synthetic parasymp...

Multiple Sclerosis (MS) patients are often referred to aquatic physical therapy, but unfortunately, researches on the effects of aquatic therapy in MS patients are limited. The purpose of this study was to investigate the effects of Ai-Chi on balance, functional mobility, strength and fatigue in ambulatory patients with MS. Twenty-three ambulatory...

Although there are evidences as to Pilates developing dynamic balance, muscle strength and flexibility in healthy people, evidences related to its effects on Multiple Sclerosis patients are insufficient. Objectives: The aims of this study were to investigate the effects of Pilates on balance, mobility, and strength in ambulatory patients with Multi...

Abstract Enoxaparin sodium is a low molecular weight heparin (LMWH) used to treat and prevent deep venous thrombosis (DVT). The common complications related to the use of heparin are bleeding, allergic reaction, and osteoporosis. A less common complications are thrombocytopenia and thromboembolism that may not be generally recognized. We present a...

Objectives. Multiple sclerosis (MS) is an inflammatory autoimmune disorder of the central nervous system (CNS). Since a correlation between gluten intake and incidence of MS had been reported, the relationship of antigliadin antibodies and MS was debated. Case Report. We report the case of a 45-year-old female MS patient who is under interferon tre...

Reactive thrombocytosis secondary to iron-deficiency anemia (IDA) is a rare but recognized cause of stroke. We report the case of a patient with iron-deficiency anemia presenting with multiple transient ischemic attacks (TIA) due to intraluminal thrombus of an internal carotid artery. The putative mechanisms underlying anemia and stroke syndromes a...

The prevalence of pathological laughing and crying in multiple sclerosis (MS) is 10%. It has been speculated that the anatomical lesion responsible for the pathological laughing is located in the pontine base, prefrontal cortex, and cerebellum. We report an 18-year-old male patient presenting with pathological laughing and hypomania. In his neurolo...