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Publications (11)
Sequences of REPAG 3′ SS from each species of metazoa, plants and protists.
Conservation levels of REPAG and corresponding 3′AG of 11 individual 3′SS from the several species in Figures 6B,C.
Percentages of purine-rich, REPAG 3′ SS and corresponding G% of each of the 1031 species/lineages.
Python script to search for non-constitutive exons from the Ensembl-annotated transcriptomes/genomes.
Enrichment of alternative exons downstream of REPAG 3′ SS in different species.
GGG-harboring 3′ SS between the −15 and −3 positions in cancer samples or cell lines. (A) in SF3B1 mutant samples. (B) in U2AF35 mutants.
At the end of introns, the polypyrimidine tract (Py) is often close to the 3' AG in a consensus (Y)20NCAGgt in humans. Interestingly, we have found that they could also be separated by purine-rich elements including G tracts in thousands of human genes. These regulatory elements between the Py and 3'AG (REPA) mainly regulate alternative 3' splice s...
