Guive Sharifi

Guive Sharifi
Shahid Beheshti University of Medical Sciences · Department of Neurosurgery

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128
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Publications

Publications (128)
Article
Full-text available
Rho Associated Coiled-Coil Containing Protein Kinase 1 (ROCK1) is a protein serine/threonine kinase which is activated upon binding with the GTP-bound form of Rho. This protein can modulate actin-myosin contraction and stability. Moreover, it has a crucial role in the regulation of cell polarity. Therefore, it participates in modulation of cell mor...
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Background Rathke’s cleft cysts (RCCs) are common benign sellar or suprasellar lesions. The aim of this study is to report our experience on the management of 27 RCC cases. Methods We retrospectively analyzed a series of 27 patients with symptomatic RCC who were referred to our department between January 2016 and January 2020. Data regarding patie...
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Meningoencephalitis can be a diagnostic dilemma and one of its etiology are infectious causes including fungal agents. Fusarium species have attracted much attention as one of the invasive fungal infections. Major clinical manifestations of infections due to Fusarium spp. are broad such as keratitis, endophthalmitis, sino-pulmonary and central nerv...
Article
Introduction This study investigates the outcome of cerebrospinal fluid leakage repair after endoscopic transsphenoidal surgery (ETSS) sellar and parasellar lesions with fat graft. Method and materials This is a cross-sectional study designed to evaluate the results of sellar and parasellar repair with simplified method of using only fat graft as...
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Background Cushing’s disease (CD) is among the most common etiologies of hypercortisolism. Magnetic resonance imaging (MRI) is often utilized in the diagnosis of CD, however, up to 64% of adrenocorticotropic hormone (ACTH)-producing pituitary microadenomas are undetectable on MRI. We report 15 cases of MRI negative CD who underwent surgical resecti...
Article
Background and Aim: The viral agent in severe acute respiratory distress syndrome coronavirus 2 (SARS-CoV-2) is the cause of the novel coronavirus disease 2019 (COVID-19). It was first identified in December 2019 in the city of Wuhan, Hubei, China, and the World Health Organization declared it as an outbreak and a Public Health Emergency of Interna...
Article
Background Meckel’s cave is a space lateral to cavernous sinus that hosts trigeminal nerve. Cranial nerves (CN) pass from its adjacency through cavernous sinus. There has been no report of Meckel’s cave tumor with CN VI involvement while other nerves, especially trigeminal nerve, remaining preserved. Clinical presentation: A 32-year-old otherwise h...
Article
Objective: The irregular growth and proliferation of cells in the brain and skull is named brain tumor, which is an special serious type of tumor due to its location. Nowadays, brain tumor is diagnosed using imaging techniques such as Computerized_Tomography (CT), Positron_Emission_Tomography (PET), Single_Photon_Emission_Computed_Tomography (SPEC...
Article
Introduction: Follow-up management of patients with acromegaly after pituitary surgery is performed by biochemical assessment of Growth Hormone (GH) and Insulin-Like Growth Factor-1 (IGF1). There is increasing recognition of patients who show discordance results between GH and IGF1. Clinical case: We report on a 38-year-old man with facial and ear...
Preprint
Background Brain abscess (BA) is recognized as a potentially fatal neurological infection requiring appropriate and prompt treatment. Improvements in diagnostic imaging and patient care have recently changed clinical symptoms, epidemiology, and outcomes. Therefore, we aimed to review all BA patients in our referral center. Method This study retrosp...
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Introduction Rosai-Dorfman disease (RDD) usually presents with painless cervical lymphadenopathy during the two first decades of life, with or without extranodal involvement. Exclusive extranodal manifestation, and especially central nervous system (CNS) involvement, is uncommon. The etiology remains unknown and definitive diagnosis is based on cha...
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BACKGROUND Subjective hearing loss resulting from unilateral lesions of the quadrigeminal cistern region or inferior colliculus is a rare entity. OBSERVATIONS The authors presented the case of a 32-year-old man with a history of 4 months of nonpulsatile tinnitus and 1 month of unilateral sensorineural hearing loss. He was otherwise healthy with no...
Article
Introduction: Few reports are available on Cushing’s Disease (CD) occurrence in pregnancy. We report two cases of pituitary macroadenoma with initial remission, who experienced uneventful pregnancies in the setting of CD recurrence in the postpartum period. Case presentation: The cases were two women in their 30s with irregular menses, weight gain,...
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Non-coding RNAs, particularly lncRNAs and miRNAs, have recently been shown to regulate different steps in viral infections and induction of immune responses against viruses. Expressions of several host and viral lncRNAs have been found to be altered during viral infection. These lncRNAs can exert antiviral function via inhibition of viral infection...
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Long non-coding RNAs (lncRNAs), microRNAs (miRNAs), and circular RNAs (circRNAs) are non-coding transcripts which are involved in the pathogenesis of pituitary gland tumors. LncRNAs that participate in the pathogenesis of pituitary gland tumors mainly serve as sponges for miRNAs. CLRN1-AS1/miR-217, XIST/miR-424-5p, H19/miR-93a, LINC00473/miR-502-3p...
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Background Selective amygdalohippocampectomy is one of the main approaches for treating medial temporal lobe epilepsy (TLE). We herewith describe seven cases of amygdala lesions treated with selective amygdalectomy with the hippocampus saving procedure. Furthermore, we explain the trans-middle temporal gyrus transventricular approach for selective...
Article
Background Pituitary adenomas (PAs) are among the most common brain tumors which characteristically become symptomatic due to the mass effect on surrounding structures and/or hormonal imbalances. This study describes 28 cases of PAs with an extrasellar invasive growth (EIG) at the early stage of tumor growth with normal sellar cavity size. Methods...
Article
Stem cells have two important features, namely the ability for self-renewal and the capacity to differentiate into some cell kinds with specialized functions. These two features are also present in cancer stem cells (CSCs). These cells have been detected in almost all kinds of cancers facilitating their tumorigenicity. Molecular cascades that contr...
Article
Background Developmental venous anomaly (DVA) is a benign venous abnormality draining normal brain parenchyma. It is mostly asymptomatic; however, rare complications such as hemorrhage may lead to symptomatic conditions. Headache and seizure are the most common symptoms. Hearing loss is an extremely rare presentation of DVA. To our knowledge, only...
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Tumors of the nervous system can be originated from several locations. They mostly have high mortality and morbidity rate. The emergence of resistance to chemotherapeutic agents is a hurdle in the treatment of patients. Long non-coding RNAs (lncRNAs) have been shown to influence the response of glioblastoma/glioma and neuroblastoma to chemotherapeu...
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Neurofibromatosis type 1 (NF1) is associated with peripheral and central nervous system tumors. It is noteworthy that the regions in which these tumors frequently arise are the optic pathways (OPs) and the brainstem. Thus, we decided to trace the procedure of diffusion Magnetic Resonance Imaging (dMRI) alterations along with Short-Wavelength Automa...
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Glioblastoma is the utmost aggressive diffuse kind of glioma which is originated from astrocytes, neural stem cells or progenitors. This malignant tumor has a poor survival rate. A number of genetic aberrations and somatic mutations have been associated with this kind of cancer. In recent times, the impact of long non-coding RNAs (lncRNAs) in gliob...
Article
Background and Aim: EETA (Endoscopic Endonasal Transsphenoidal Approach) is a preferred choice for pituitary tumors. EETA offers minimal invasiveness, fewer complications, and better outcomes than the sublabial or transseptal microscopic approach. EETA has three approaches: mononostril endoscopic transsphenoidal approach, binostril endoscopic trans...
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Background: It is believed that pituitary carcinoma is a rare disorder and arise from the transformation of benign invasive macroadenomas, and the process of this transformation takes place slowly. Case presentation: A 51-year-old man presented with the clinical features of Cushing syndrome and walking impairment who was diagnosed with metastati...
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Background The origin of meningioma tumors is known as the meningothelial or arachnoid cap cells. The arachnoid granulations or villi are concentrated along with the dural venous sinuses in the cerebral convexity, parasagittally, and sphenoid wing regions. The majority of meningiomas are found in these locations with dural attachment. Infrequently,...
Article
Background and Aim: One of the most prevalent neurosurgery conditions is Chronic Subdural Hematoma (CSDH). Among neurosurgeons, there are various CSDH treatment approaches. Methods and Materials/Patients: This is a narrative review examining the various aspects of the CSDH. To provide up-to-date information on CSDH, we concisely reviewed the relate...
Article
Introduction: Spheno-orbital en plaque meningioma is located in a sensitive and complex cranial region. Therefore, the therapeutic approach for this type of tumor is of great importance. We aimed to examine the clinical and radiological outcomes of patients diagnosed with sphenoid wing en plaque meningioma undergoing surgery. Methods: In this ca...
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The authors report a pathologically confirmed case of primary malignant melanoma located in the intradural lumbosacral area, which is extremely rare due to its atypical location and manifestation. However rare, primary malignant melanoma could present as an intradural tumor and cause neurological deficit.
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Schwannoma is a benign, slow-growing sheath tumor that arises in peripheral nerves. Tumors involving olfactory bulbs and tracts are extremely rare, and only a limited number of cases have been reported. Our case was a 30-year-old man presenting with a one-year history of anosmia and no other remarkable history or finding in the physical examination...
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Purpose: Glioma cell infiltration, in which the glioma tumor cells spread long distances from the primary location using white matter (WM) or blood vessels, is known as a significant challenge for surgery or localized chemotherapy and radiation therapy. Following the World Health Organization (WHO), the glioma grading system ranges from stages I to...
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Spindle cell oncocytoma (SCO) is a rare tumor of adenohypophysis, arising from the sellar region. So far, about 35 cases of SCO in the sellar region have been reported. In this report, we present the first case of pediatric SCO and review the literature concerning the tumor origin, clinical presentations, radiological features, and treatment modali...
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Background : Acromegaly defines as chronic elevations of insulin-like growth factor-1 (IGF-1) and growth hormone (GH), which results in enlargement of organs and soft tissues. Cardiovascular complications of acromegaly such as cardiomegaly, hypertension contributing to a high risk of cardiovascular events. This study aimed to identify the determina...
Preprint
Choroid plexus tumors (CPTs) are rare choroid plexus epithelium originated neoplasms. Among all, choroid plexus papilloma (CPP) is the most common type of CPT. Clinical features and signs at diagnosis of CPP in CPA are so extensive and also nonspecific. This work aimed to review the sign and symptoms of CPP tumors in CPA through all cases reported...
Article
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Cerebrospinal fluid (CSF) rhinorrhea complicates 2% of all head traumas, and 12%-30% of all basilar skull fractures. Posttraumatic CSF rhinorrhea usually occurs within the first 48 h, and majority of them occur in the first 3 months, whereas delayed CSF leak beyond 3 months is rare. On the other hand, CSF usually leaks through dural tearing associa...
Article
Introduction: Brain tuberculoma is a rare manifestation of tuberculosis especially in immunosuppressed patients. The definite diagnosis may be difficult due to mimicking the brain tumors and the absence of the common presentation. Bacille Calmette-Guérin (BCG) vaccine is used for protection against tuberculous meningitis and miliary disease, more...
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Quality of life is affected by factors such as regional differences in access to treatment choices, and rehabilitation. This study aims to assess the result of epilepsy surgery and its impact on QoL in Iran. The data for 60 patients who underwent epilepsy surgery in Loghman-Hakim hospital between 2003 to 2017 were analyzed prospectively through cli...
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Background: Presurigical planning for glioma tumor resection and radiotherapy treatment require proper delineation of tumoral and peritumoral areas of brain. Diffusion tensor imaging (DTI) is the most common mathematical model applied for diffusion weighted MRI data. Neurite orientation dispersion and density imaging (NODDI) is another mathematica...
Article
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Background Brain tumor is one of the most common tumors. A successful treatment might be achieved with an early identification. Pathological investigation as the gold standard method for tumor identification has some limitations. Noninvasive assessment of tumor specifications may be possible using perfusion-weighted magnetic resonance imaging (MRI)...
Article
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Background and Importance: Symptomatic Rathke’s cleft cyst is a rare lesion that often presents without any symptoms. Case Presentation: We report a 40-year-old female with symptomatic Rathke’s cleft cyst located in the sellar and suprasellar region. She presented with visual disturbance, headache, weight gain, hypothyroidism and amenorrhea. The p...
Article
Background Abnormalities of the posterior arch of vertebrae are rare conditions that may incidentally be found on neck radiographs. We report a case and present a comprehensive review of the literature. Case Description A 10-year-old boy presented with intermittent paresthesia in the lower extremities, mild neck pain, and episodes of drop attacks...
Article
Objectives: The endoscopic approach increasingly is used to treat third ventricular colloid cysts. Our objective was to assess the results of endoscopic resection of colloid cysts of the third ventricle. Methods: A retrospective study was designed, and a series of 112 consecutive patients (76 male, 36 female) with third ventricular colloid cyst...
Article
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Background and Importance: This interesting case is about the presence of normal pressure hydrocephalus and a large pseudomeningocele at the same time after 13 months of posterior fossa surgery. Although the occurrence of a pseudomeningocele following posterior fossa surgery is not so rare, such a late large pseudomeningocele development with signs...
Article
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Background: Studies collectively imply that the reciprocal link has no effect on walking when using reciprocating gait orthoses (RGOs). There may be differences between the 2 configurations of the RGO (eg, isocentric reciprocating gait orthosis [IRGO] and IRGO without reciprocating link), but the specific benefits and problems encountered in their...
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Background: Excessive bleeding is an unwanted complication of transsphenoidal resection of pituitary adenoma due to increases in intracranial pressure (ICP) and hemodynamic instability. Dexmedetomidine (Dex) anα2agonists is the drug of choice in intensive care units (ICU) and cardiac surgeries to control abrupt changes in hemodynamic. Severe cardi...
Article
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Schwannomais, usually, benign tumor of nerve sheath that occurs evenly along the spinal cord. Intra-pelvic schwannoma is very rare entity that may arise from lumbosacral nerve roots or from sciatic nerve. Radicular pain of the lower limb as a presenting symptom of pelvic schwannoma is extremely rare. In the current report, the patient is presented...
Article
Background: Knee-ankle-foot orthoses (KAFOs) are used by people with poliomyelitis to ambulate. Whist advances in orthotic knee joint designs for use in KAFOs such the provision of stance control capability have proven efficacy, little attention has been paid to shoe adaptations which may also improve gait. Aim: The aim of this study was to eval...
Article
Background: Adolescent idiopathic scoliosis (AIS) is a progressive growth disease that affects spinal anatomy, mobility, and left-right trunk symmetry. The disease can modify human gait. Objective: We aimed to review articles describing the measurement of gait parameters and energy consumption in AIS during walking without any intervention. Stu...
Article
Background: Colloid cyst is a gelatin-containing cyst in the brain almost always found in the third ventricle. The specific shape and location of these cysts, a round well-delineated mass in the rostral part of the third ventricle adjacent to the foramen of Monro, on imaging are the main findings for diagnosis. Several masses of the third ventricl...
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In this research, we analyzed the EEG signals of patients with brain tumor and healthy participants in order to study the effects of brain tumor on brain signals and also the feasibility of brain tumor detection using EEG signals. For this reason, EEG signals of four channel F3, F4, T3 and T4 from 5 patients with brain tumor and 4 healthy participa...
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Introduction: Pituitary adenoma producing symptomatic carotid compression of the internal carotid artery without any apoplexy sign would be extremely rare and there was only one report regarding to this condition. Case Presentation: In this case report we have described a 57-year-old woman with a nonfunctional pituitary macro adenoma which has resu...
Article
Drug-resistant epilepsy seems like a different disease compared with easy to control epilepsy, and new strategies are needed to help these patients. Vagus nerve stimulation (VNS) therapy is the most frequently used neurostimulation modality for patients with drug-resistant epilepsy who are not eligible for seizure surgery. In this study, we aimed t...
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Context The National institute for health and care excellence (NICE) and scottish intercollegiate guidelines network (SIGN) are two well-known sources of clinical guideline development. In the past years, they have developed clinical guidelines for the management of head injury. In this report, we will highlight our modifications to these guideline...
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Background & Importance: Acute autonomic system impairment can be dangerous and life-threatening, and a clinician should be aware of its occurrence possibility. According to the anatomy of this system, spinal cord lesions could disturb its function. There are many reports of autonomic dysreflexia in spinal cord i njuries especially spinal cord trau...