Guillermo Ortega Avila

Guillermo Ortega Avila
  • Doctor of Biomedical Sciences
  • Reseacher and Professor at Pontificia Universidad Javeriana - Cali

About

45
Publications
6,031
Reads
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364
Citations
Current institution
Pontificia Universidad Javeriana - Cali
Current position
  • Reseacher and Professor

Publications

Publications (45)
Article
Full-text available
Background Differences in adolescents and adults by sex in blood levels of leptin and adiposity have been described; however, it is not yet clear if these differences arise from the prepubertal stage in subjects with a normal-weight. Therefore, we examine whether there are differences by sex in levels of blood leptin and adiposity in children with...
Article
Full-text available
Sacha inchi oil (SIO) is an attractive source of polyunsaturated acids oil. A randomized crossover clinical trial was done to evaluate SIO effects on postprandial lipids and inflammatory state caused by a high‐fat intake. Twenty metabolically healthy (MH) and 22 metabolically unhealthy (MU) subjects consumed a high‐fat breakfast alone or supplement...
Article
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Epidemiological studies have led scientists to postulate the developmental origins of health and disease hypothesis for noncommunicable diseases such as diabetes, cardiovascular diseases, hypertension, and obesity. However, the cellular and molecular mechanisms involved in the development of these diseases are not well understood. In various animal...
Article
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Childhood malnutrition persists as a critical issue in Latin America, particularly affecting protein and iron intake among children. Biofortification, enhancing crop nutritional content, offers a promising solution rooted in Latin American culinary traditions. This study describes the nutritional features of a natural diet based on iron biofortifie...
Article
Background Little is known about the cardiorespiratory fitness (CRF)‐cardiometabolic risk relationship in Latin American pediatric populations across different age/sex groups, especially when considering the potential effects of adiposity on the association. We evaluated cross‐sectional associations between VO 2max and cardiometabolic risk variable...
Article
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Background This systematic review and meta-analysis aimed to assess the impact of inspiratory muscle training (IMT) on lung function parameters (MIP, MEP, FEV1, and FVC) between both elite and non-elite swimmers. Methods We searched for controlled clinical trials (CCT) and prospective longitudinal studies (PLS) in elite and non-elite swimmers foll...
Article
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Introduction. Altered serum zinc levels, lower and higher than values in healthy controls, have been observed in individuals affected by non-communicable chronic diseases. However, to date, studies describing potential determinants of zinc levels in general populations free of chronic diseases appear to be limited. Objective. To evaluate whether n...
Article
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Depressive and anxiety disorders have been associated with body mass index (BMI), since mesolimbic reward circuits, such as dopamine secretion and the expression of dopamine neuronal receptors, have been related to weight in people with mental issues. However, few studies have analyzed polymorphisms of genes of the dopaminergic system in healthy po...
Article
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Objectives: This study aimed to evaluate cytogenetic damage in the buccal mucosa of non-exposed subjects (N = 33) and insecticide-exposed fumigators (N = 31) in the urban area of Cali, Colombia. Material and Methods: Through a questionnaire sociodemographic data, anthropometric measurements, state of health, and lifestyle were collected. Buccal mic...
Article
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Introducción: en la Región no Traducida (UTR) 3’ del gen SLC6A3 que codifica para el transportador de dopamina 1 (DAT1), se ha descrito la presencia de Repeticiones en Tándem de Número Variable (VNTR) que según su longitud pueden afectar la expresión de la proteína y la recaptación dopaminérgica, lo que podría contribuir al desarrollo de trastornos...
Article
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Objective Information about excess adiposity markers different from BMI and iron status is limited and more so about the shape of these associations. This study evaluated the relationship between three adiposity markers and iron‐deficient status in reproductive‐age women. Methods Cross‐sectional analysis in 6357 non‐pregnant women from the Colombi...
Article
Introduction Medical students use to deal with high levels of academic stress. Hatha yoga and meditation have been found to reduce variables associated with stress. Objective: To evaluate and compare the effect of Hatha yoga and meditation on academic stress in medical students at a private university in Cali, Colombia. Methods and Materials A tot...
Article
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RESUMEN El método madre canguro, brinda prácticas de cuidado y atención al neonato prematuro o de bajo peso al nacer que favorecen su desarrollo en la etapa post-natal. Esta investigación busca establecer la distribución de percentiles antropométricos de talla, peso y perímetro cefálico (PC), de los recién nacidos de un programa de seguimiento de b...
Article
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Iron deficiency contributes to the global burden of disease, affecting children, premenopausal women, and population from low-income and middle-income countries. To manage the deficit of iron on diet, biofortified crops can be obtained from conventionally plant-based foods. BIO102 bean is a biofortified crop with higher iron and protein content whe...
Article
Background: Obesity is a public health problem worldwide; it has reached pandemic proportions in the last 40 years. Its prevalence in children and adolescents increased from 0.7% to 7.8% between 1975 and 2016. Recently, microRNAs (miRNAs) have been reported as regulatory factors related to molecular functions under different conditions. These can b...
Article
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Body iron excess appears to be related to insulin resistance and cardiometabolic risk and increased oxidative stress might be involved in this relationship. Very few studies have described the association between soluble transferrin receptor (sTfR) levels and cardiometabolic risk in the general population or antioxidant status. There were 239 subje...
Article
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os estudiantes del área de la salud presentan altos niveles de estrés ante las exigencias académicas, lo que repercute negativamente en su salud y su desempeño académico. Debido a que afecta el funcionamiento fisiológico de diferentes procesos metabólicos, hormonales e inmunológicos, se han implementado estrategias para hacerle frente; de allí que...
Article
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The postprandial stage is related to an increase in biochemical and cellular inflammatory markers. The objective of this study was to evaluate the postprandial effects of the addition of Sacha inchi oil on the concentration and size of leukocytes, erythrocytes and platelets, and on inflammation markers, after the ingestion of a high-fat meal. A sam...
Article
Full-text available
The prepubertal stage is a critical period of body fat development, in which leptin and insulin resistance has been associated, however, there are few studies in normal-weight prepubescents. Objective: To assess the relationship between leptin and body composition and insulin resistance in a group of normal-weight prepubescents. Patients and Method...
Article
After a snakebite accident, species identification is of vital importance. However, the existence of intraspecific differences in the body coloration patterns of venomous snakes can generate confusion and delay a convenient and effective treatment. This is the situation for Porthidium lansbergii lansbergii from Colombia, for which two distinctive c...
Poster
The maternal endothelial function is a critical factor for the normal development of pregnancy and fetus. This function is mainly modulated by the production of Nitric Oxide derivated from endothelium. The excess of ROS during the gestation has been related with endothelial dysfunction, vascular diseases and alterations in the fetal growth.For this...
Poster
In the present study, we explored the potential of metabolomics to evaluate the effect to micronutrient supplementation and regular aerobic exercise on the metabolic profile at 20 and 32 weeks of gestation during a healthy pregnancy. Study was performed on serum samples obtained at 20 and 32 weeks from 200 pregnant women attending usual prenatal ca...
Article
Background: The postprandial stage is related to cardiovascular risk and it depends on the type of meal consumed. We study the effects of Sacha inchi oil on the postprandial glycemic state caused by meals rich in saturated fat. Methods and results: A double blind randomized trial in which 42 adult men ingested two breakfasts rich in saturated fa...
Article
Full-text available
To evaluate the Relationship between maternal and newborn endothelial function and oxidative stress. Forty-three pregnant women and their offspring were evaluated. As markers of endothelial function, the flow-mediated dilation (FMD) was measured in pregnant women in the second and third trimesters, and nitric oxide (NO) was quantified in the endoth...
Article
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Introducción. La aterosclerosis es una enfermedad crónica asintomática que se inicia a edad temprana y es de difícil detección en esta etapa. Los estudios prospectivos sugieren una relación causal entre el nivel de colesterol sérico total en la niñez y la adolescencia, y el desarrollo de enfermedades cardiovasculares en la adultez. Objetivo. El ob...
Article
Objective Recently, non-pharmacological resources to relieve pain like hot packs and ultrasound (US) have become common in clinical practice. However, little experimental evidence is available about the possible mechanisms through which these methods bring about pain relief. We aimed to determine the effects of hot packs and US on the acute vascula...
Article
Reference data for anthropometric parameters are not available for adolescents in Cali (Colombia). This study aimed to develop representative age- and sex-specific percentiles for anthropometric indicators [fat percentage, body mass index (BMI), and waist circumference] in urban adolescents aged 10-16 years in Cali. The sample (n=1,773) consisted o...
Article
Objective: Recently, non-pharmacological resources to relieve pain like hot packs and ultrasound (US) have become common in clinical practice. However, little experimental evidence is available about the possible mechanisms through which these methods bring about pain relief. We aimed to determine the effects of hot packs and US on the acute vascu...
Article
To assess age- and sex-specific percentile baseline data for total cholesterol (TC), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C) in Colombian children and adolescents aged 10 to 17 years. A cross-sectional, descriptive study was conducted on 1,773 children and adolescents. Each participant underwent a fasting measurement to...
Article
To evaluate the effect of regular aerobic exercise on the endothelial function and cardiorespiratory fitness in pregnant women. This was a randomized, double-blinded, controlled clinical trial of 64 healthy primigravid women between 16 and 20 weeks' gestation. The experimental group took part in aerobic exercise at an intensity of 50-65% of their m...
Article
Full-text available
Baseline data for physical condition are not available for adolescents in Cali, Colombia. This study aimed to develop representative age- and sex- specific percentile baseline data for physical condition (mL.kg-1.min-¹) for urban adolescents aged 10-16 years. Materials and methods. The sample (n=1,773) consisted of 865 males and 908 females from th...
Article
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Objetivo: evaluar, en mujeres primigestantes saludables, el efecto del ejercicio aeróbico sobre el consumo de oxígeno. Materiales y métodos: estudio clínico aleatorizado en 64 mujeres saludables, primigestantes, entre 16 y 20 semanas de gestación. Grupo de intervención: ejercicio aeróbico entre el 50% y 65% de la frecuencia cardíaca máxima, durant...
Article
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Objective: evaluating the effect of aerobic exercise on oxygen consumption by healthy first-pregnancy females. Materials and methods: a randomized clinical trial was carried out on 64 healthy first-pregnancy females (16 to 20 weeks pregnant). Intervention group: aerobic exercise involving 50% to 65% maximum heart rate for 45 min, 3 times a week ove...
Article
Full-text available
Many studies have suggested a relationship between metabolic abnormalities and impaired fetal growth with the development of non-transmissible chronic diseases in the adulthood. Moreover, it has been proposed that maternal factors such as endothelial function and oxidative stress are key mechanisms of both fetal metabolic alterations and subsequent...
Article
Objective. The purpose of this pilot study is to describe the use of the Kinesio Taping ® (KT) method for the upper extremity on vascular function and morphology in healthy subjects. Methods. Experimental trial in six participants. Vascular measurements were performed by high-resolution plethysmography (arterial compliance, arterial elastic, beta i...
Article
OBJECTIVE: evaluate the effect of aerobic exercise on endothelium-dependent function (EDF) and oxygen consumption in primigravida. METHODS: double-blind, randomized controlled clinical trial carried out in primigravida between 16 to 20 weeks of gestation. The intervention group had aerobic exercise between 50% to 65% of the maximum heart rate durin...
Article
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Evaluar el efecto del ejercicio aeróbico en la función dependiente del endotelio (VDE) y en el consumo de oxígeno en mujeres primigestantes. Métodos: Ensayo clínico controlado, enmascarado y aleatorizado, llevado a cabo en 67 mujeres saludables, primigestantes, entre 16 a 20 semanas de gestación. Grupo de intervención: ejercicio aeróbico entre 50%...
Article
Background Reduced cardiorespiratory function is an independent risk factor for mortality by all causes, but mainly for coronary heart disease. Nevertheless, there are many difficulties in evaluating it by exercise testing in the epidemiological context. Alternative forms of evaluation have therefore been suggested using non-exercise regression mod...
Article
Full-text available
Introducción: En la actualidad casi todos los esfuerzos para prevenir las enfermedades crónicas no transmisibles (ECNT) a nivel poblacional, se han centrado en promover comportamientos saludables como el ejercicio, la actividad física, el consumo de frutas y verduras, y el desestimular el consumo de tabaco y alcohol en la población adulta, pero los...
Article
Full-text available
Introducción: En la actualidad casi todos los esfuerzos para prevenir las enfermedades crónicas no transmisibles (ECNT) a nivel poblacional, se han centrado en promover comportamientos saludables como el ejercicio, la actividad física, el consumo de frutas y verduras, y el desestimular el consumo de tabaco y alcohol en la población adulta, pero los...
Article
Fonament: Una reduïda capacitat funcional o VO2màx és considerada com a factor de risc que provoca la mort per múltiples causes, però principalment per malaltia coronària. Per això, i sumat a la dificultat que representa avaluar-la, han estat suggerides altres alternatives per fer-ho, tot desenvolupant equacions de predicció, sense la necessitat de...

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