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Guilherme Malafaia

Guilherme Malafaia
Goiano Federal Institute - Campus Urutaí (Brazil)

Doctor
Permanent Professor, Department of Biological Sciences, Goiano Federal Institute - Campus Urutaí (Brazil)

About

304
Publications
52,052
Reads
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2,765
Citations
Citations since 2016
213 Research Items
2505 Citations
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Introduction
Dr. Malafaia (Guilherme) He is a Professor in the Department of Biological Sciences at Federal Institute of Education, Science and Technology Goiano (Brazil). He received a bachelor’s degree from Federal University of Ouro Preto, a MS from Federal University of Goiás, PhD and Postdoc from Federal University of Goiás, all related to Environmental and Biological Sciences. He is directing the Biological Research Laboratory with a focus on the ecotoxicological assessment of emerging pollutants.
Additional affiliations
August 2021 - present
Instituto Federal Goiano
Position
  • Professor

Publications

Publications (304)
Article
The dispersion of SARS-CoV-2 in aquatic environments via the discharge of domestic and hospital sewage has been confirmed in different locations. Thus, we aimed to evaluate the possible impacts of zebrafish (Danio rerio) exposure to SARS-CoV-2 peptide fragments (PSPD-2001, 2002, and 2003) alone and combined with a mix of emerging pollutants. Our da...
Article
The COVID-19 era has profoundly affected everyday human life, the environment, and freshwater ecosystems worldwide. Despite the numerous influences, a strict COVID-19 lockdown might improve the surface water quality and thus provide an unprecedented opportunity to restore the degraded freshwater resource. Therefore, we intend to investigate the spa...
Article
Although the in vivo toxicity of nanoplastics(NPs) has already been reported in different model systems, their effects on mammalian behavior are poorly understood. Thus, we aimed to evaluate whether exposure to polystyrene (PS) NPs (diameter: 23.03±0.266 nm) alters the behavior (locomotor, anxiety-like and antipredator) of male Swiss mice, induces...
Article
Although microplastic (MP) pollution of aquatic ecosystems is a high-priority study topic, the issue of terrestrial environment and textile manufacturing waste has received little attention. Thus, this study was carried out to investigate the presence of MPs in agricultural land near textile industries and textile sludge samples in Bangladesh. Thir...
Article
The water bodies in Bangladesh thrive from plastic pollution. Estuaries are pools of environmental contaminants, and the world's largest mangrove forest, Sundarbans' estuary, is no exception. Thus, for the first time, we investigate MPs abundance in the muscle and gastrointestinal tract (GIT) of twenty estuarine species of fish and shellfish of the...
Article
Water consumption has grown in recent years due to rising urbanization and industry. As a result, global water stocks are steadily depleting. As a result, it is critical to seek strategies for removing harmful elements from wastewater once it has been cleaned. In recent years, many studies have been conducted to develop new materials and innovative...
Article
Full-text available
Curculigo orchioides rhizome explants were employed to develop a rapid and effective strategy for increased plant regeneration using somatic embryogenesis. Direct somatic embryo development was shown on rhizome explants cultivated on Murashige and Skoog (MS) making with 2, 4-D (1.0–3.0 mg/L). Rhizome explants cultivated on MS media supplemented wit...
Article
Due to their huge surface area to volume ratio, metallic nanoparticles are becoming increasingly important in numerous spheres of life. Here, initially, we aimed to evaluate the potential use of Cassia auriculata (CA) extract to synthesize silver nanoparticles (AgNPs). Then, we evaluated its antimicrobial potential and antioxidant capacity, as well...
Article
Groundwater from the coastal alluvial plain is the primary water source in coastal areas. Its contaminants, such as nitrate and fluoride, are significant concerns for freshwater supply and human health issues. Although spatiotemporal variability of nitrate and fluoride levels has been analyzed individually in the Indo-Bangladesh coastal region, the...
Article
The use of vegetal species for gold nanoparticles (AuNPs) biosynthesis can constitute an alternative to replacing the extensive use of several hazardous chemicals commonly used during NPs synthesis and, therefore, can reduce biological impacts induced by the release of these products into the natural environment. However, the “green nanoparticles”...
Article
Difenoconazole is widely used to protect crops, fruits, and vegetables. However, this fungicide can enter aquatic environments and cause harmful effects to non-target organisms and induce little-known biological disorders. Thus, aiming to expand our knowledge about the ecotoxicity of difenoconazole on freshwater ichthyofauna, we aimed to determine...
Article
The resistance to insecticides among insects, including mosquitoes and agricultural pests, and the impact of these compounds' environmental risks and health issues have motivated the proposition of eco-friendly alternatives. Thus, we aimed to explore the potential use of Desmostachya bipinnata for the biosynthesis of TiO2NPs and evaluate their larv...
Article
Although numerous drugs are practiced to control malaria and its vectors, more recently, eco-friendly control tools have been proposed to battle its etiologic agents. Thus, using green bionanotechnology approaches, we aimed to synthesize palladium nanoparticles (Pd NPs) from the macroalgae Sargassum fusiforme (Sf), its potential antiparasitic activ...
Article
Bisphenol-A (BPA) is a plasticizer commonly used in the plastics industry to manufacture plastic materials. It is abundant in aquatic ecosystems, resulting in increased contamination and lower concentrations that may represent a significant threat to the aquatic system. Hence in the present study, an Indian major carp, Labeo rohita, was exposed to...
Preprint
Full-text available
Spatial-temporal variability of fluoride in water has been a major global health concern. However, in Turkey, there has been very limited research quantifying the probabilistic health risks from fluoride accumulations in the water of natural-artificial lakes. Thus, we aim to determine the spatial-temporal variability and probabilistic health risk o...
Preprint
Full-text available
Despite all efforts to combat the pandemic of COVID-19, we are still living with high numbers of infected persons, an overburdened health care system, and the lack of an effective and definitive treatment. Understanding the pathophysiology of the disease is crucial for the development of new technologies and therapies for the best clinical manageme...
Article
Full-text available
Regulation of inflammation is a critical process for maintaining physiological homeostasis. The λ-carrageenan (λ-CGN) is a mucopolysaccharide extracted from the cell wall of red algae (Chondrus crispus) capable of inducing acute intestinal inflammation, which is translated into the production of acute phase reactants secreted into the blood circula...
Article
Mosquitoes' current insecticide resistance status in available public health insecticides is a serious threat to mosquito control initiatives. Microbe-based control agents provide an alternative to conventional pesticides and insecticides, as they can be more targeted than synthetic insecticides. The present study was focused on identifying and inv...
Article
More recently, many studies have reported the impacts of microplastics (MPs) on the health of organisms. However, our knowledge of its effects on some vertebrate groups, such as amphibians remains incipient. Thus, we evaluated whether the exposure of Physalaemus cuvieri tadpoles to MPs from shoe soles can induce harmful effects on their health. Aft...
Article
The input of SARS-CoV-2 or its fragments into freshwater ecosystems (via domestic or hospital sewage) has raised concerns about its possible impacts on aquatic organisms. Thus, using mayfly larvae [Cloeon dipterum (L.), Ephemeroptera: Baetidae] as a model system, we aimed to evaluate the possible effects of the combined short exposure of SARS-CoV-2...
Article
Plant extracts' ability to collect metals and decrease metal ions makes them a superior candidate for the biosynthesis of nanoparticles; hence, they are referred to as bio-nano factories since both living and dead dried biomass are employed to produce metallic nanoparticles. The antiparasitic activity of biosynthesized copper oxide nanoparticles (C...
Article
Pesticides are widely used in agricultural production; moreover, they can have direct and indirect effect on both flora and fauna. Aquatic organisms, among other animals, including reptiles, are mainly susceptible to contamination effects. Accordingly, the aim of the present study is to test the hypothesis that the incubation of Podocnemis expansa...
Article
Microplastic pollution is a global concern, mainly due to its adverse effects on organisms and ecosystems. However, our knowledge of its impact on humans, in particular, is still very limited. Thus, while we have not gathered definitive information on their consequences, studies that aim to identify the MP's sources constitute subsidies to better u...
Article
Although several studies are confirming the ubiquity of microplastics (MPs) in environments, our knowledge about their effects on human health is still very limited. Therefore, while we have not gathered definitive information on their consequences, studies that aim to identify the MPs sources constitute subsidies to better understand the various e...
Article
Studies in recent years have shown that aquatic pollution by microplastics (MPs) can be considered to pose additional stress to amphibian populations. However, our knowledge of how MPs affect amphibians is very rudimentary, and even more limited is our understanding of their effects in combination with other emerging pollutants. Thus, we aimed to e...
Article
Full-text available
Glial cell line-derived neurotrophic factor (GDNF) and its receptor (GDNF Family Receptor α1-GFRα1) are well known to mediate spermatogonial stem cell (SSC) proliferation and survival in mammalian testes. In nonmammalian species, Gdnf and Gfrα1 orthologs have been found but their functions remain poorly investigated in the testes. Considering this...
Article
Despite advances in research on the vaccine and therapeutic strategies of COVID-19, little attention has been paid to the possible (eco)toxicological impacts of the dispersion of SARS-CoV-2 particles in natural environments. Thus, in this study, we aimed to evaluate the behavioral and biochemical consequences of the short exposure of outbred and in...
Article
Worldwide, the bird cherry-oat aphid, Rhopalosiphum padi, (R. padi) affects wheat, sorghum, and other grain crops, and conventional pesticides to control this aphid negatively affects the surrounding environment. Therefore, knowing the entomotoxicity of different chemical compounds against R. padi is an important step to control these pests. Thus,...
Article
Despite the toxicity of microplastics (MPs) in freshwater fish has been demonstrated in previous studies, their effects when mixed with other pollutants (organic and inorganic) are poorly understood. Thus, we aimed to test the hypothesis that the association of polyethylene MPs (PE-MPs) to a mix of emerging pollutants induces more adverse genotoxic...
Article
In recent years, there has been a growing number of studies on the impact of microplastics (MPs) on biota. However, its effects on birds’ health are poorly understood. Thus, we aimed to evaluate the possible effects of ingestion of naturally-aged MPs by Coturnix coturnix japonica (11 and 22 MP particles/day/bird, once a day, for 9 days), from diffe...
Article
There have been significant impacts of the current COVID-19 pandemic on society including high health and economic costs. However, little is known about the potential ecological risks of this virus despite its presence in freshwater systems. In this study, we aimed to evaluate the exposure of Poecilia reticulata juveniles to two peptides derived fr...
Article
The identification of SARS-CoV-2 particles in wastewater and freshwater ecosystems has raised concerns about its possible impacts on non-target aquatic organisms. In this particular, our knowledge of such impacts is still limited, and little attention has been given to this issue. Hence, in our study, we aimed to evaluate the possible induction of...
Article
The toxicity of microplastics (MPs) has been demonstrated in several previous studies, exposing different model organisms to fluorescent-labeled particles. However, many of these studies did not report the use of control groups for unbound and leaching dyes, which limits the conclusions about the bioaccumulative potential of these micromaterials an...
Article
In recent decades, the ecotoxicological potential of organic ultraviolet filters (OU-VFs) has received growing attention. However, the toxicity of its photoproducts or transformation products on freshwater vertebrates has been little explored. Therefore, the aim of the present study is to evaluate the possible adverse effects of ethylhexyl methoxyc...
Article
Steel wool (SW) has a broad-spectrum of applicability, particularly as abrasives, cleaning household utensils and surfaces in general. However, when present in the natural environment, they can be ingested by animals, such as birds, and may represent a risk to the survival of individuals. Accordingly, in this study, we attempted the hypothesis that...
Article
For our knowledge, the roadside soils end up being the deposit of various residues discarded by drivers or passengers, plus, that coming from the runoff of rainwater. Basically, we do not know the impacts that this pollution causes on animals which inhabit these environments. Thus, in this study, our objective was to evaluate how the presence of pl...
Preprint
Full-text available
Glial cell line-derived neurotrophic factor (GDNF) and its receptor (GDNF Family Receptor α1 - GFRα1) are well known to mediate spermatogonial stem cell (SSC) proliferation and survival in the mammalian testes. In nonmammalian species, Gdnf and Gfrα1 orthologs have been found but their functions remain poorly investigated in the testis. Considering...
Article
Despite the significant increase in the generation of SARS-CoV-2 contaminated domestic and hospital wastewater, little is known about the ecotoxicological effects of the virus or its structural components in freshwater vertebrates. In this context, this study evaluated the deleterious effects caused by SARS-CoV-2 Spike protein on the health of Dani...
Article
Currently, the evidence of the ingestion of microplastics (MPs) by organisms or the accumulation in different environmental compartments has been achieved using several methodological procedures. However, its uses have not been standardized across studies. In this study, we aim to assess and validate a protocol that can be useful for optimizing the...
Article
Although the toxicity of microplastics has already been demonstrated in different animal models, our knowledge about the response of freshwater fish to this pollutant is still limited. Thus, we aimed to evaluate the impact of exposure of zebrafish adults (Danio rerio) to environmentally relevant concentrations of polyethylene microplastics (PE-MPs)...
Article
Different strategies focused on mitigating, remedying, or preventing the intensification of environmental issues have been adopted by several institutions, organizations, governments, media, among others. One of these strategies lies on environmental advertising campaigns based on creative and eye-catching advertisements aimed to promoting the envi...
Article
Despite plastic ingestion has already been reported in several bird species, its physiological impacts have been little inspected, especially in representatives of the Cathartidae family. Thus, in this study, we aimed to identify, characterize, and evaluate the effects arising from the ingestion of plastic materials by Coragyps atratus adults, that...
Article
Although the toxicity of nanoplastics (NPs) has already been reported in experimental aquatic models, their possible effects on the reproductive performance of viviparous freshwater fish and their consequences for embryos, so far, are unknown. Thus, we aimed to evaluate whether the gestational exposure of Poecilia reticulata to polystyrene NPs (PS...
Article
Although the toxicity of neonicotinoid insecticides has been demonstrated in several studies, the information on metabolism, behavior, and health risk remains limited and has raised concerns about its potential toxicity. Thus, in this study we assessed the effects of nitenpyram using different sublethal concentrations (one-third and one-tenth of th...
Article
The impacts of anthropogenic activities they affect biotic and abiotic factors in charge of ecosystem balance. Therefore, different didactic-pedagogical resources and activities for environmental education (EE) in schools have been suggested; however, approaches aimed at early school years are scarce in the literature. Thus, the general objective o...