Guido Simonelli

Guido Simonelli
Université de Montréal | UdeM · Department of Medicine

MD

About

58
Publications
5,746
Reads
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656
Citations
Citations since 2017
48 Research Items
606 Citations
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2017201820192020202120222023050100150
2017201820192020202120222023050100150

Publications

Publications (58)
Article
Full-text available
To evaluate the effect of a housing transition on sleep quality and quality of life in slum dwellers, participating in a slum housing upgrading program. Observational before-and-after study with a convergent-parallel mixed method design. Five slums located in the metropolitan area of Buenos Aires, Argentina. A total of 150 slum dwellers benefited b...
Article
Full-text available
Study objectives: To evaluate whether an adverse neighborhood environment has higher prevalence of poor sleep in a US Hispanic/Latino population. Methods: A cross-sectional analysis was performed in 2156 US Hispanic/Latino participants aged 18-64 years from the Sueño ancillary study of the Hispanic Community Health Study/Study of Latinos (HCHS/S...
Article
Sleep research has been dominated by high income countries (HIC). Sleep may be different in low and middle income countries (LMIC) due to cultural, demographic, geographical and health factors. We systematically reviewed the epidemiological literature reporting sleep parameters in the adult population in LMIC and meta-analyzed the prevalence of sub...
Article
Sleep quality appears to be altered by traumatic brain injury (TBI). However, whether persistent post-injury changes in sleep architecture are present is unknown and relatively unexplored. We conducted a systematic review and meta-analysis to assess the extent to which chronic TBI (>6 months since injury) is characterized by changes to sleep archit...
Article
Introduction: Insufficient sleep increases pain sensitivity in healthy individuals. Additionally, extending sleep (eg, increasing nocturnal sleep time or adding a mid-day nap) has been shown to restore pain sensitivity to baseline levels in sleep deprived/restricted individuals. Whether sleep extension can reduce pain sensitivity beyond baseline l...
Article
There are replicable inter-individual differences in cognitive responsivity to sleep loss. Genetic allele variations have been linked with behavioral differences in cognitive performance under these conditions, yet less burdensome tests or screeners are not available. This study tested whether a survey can classify U.S. Army Soldiers as cognitively...
Article
Scientists in sleep and circadian rhythms, public health experts, healthcare providers, partners, and stakeholders convened in 2020 for a 2-day meeting organized by the Canadian Sleep and Circadian Network to develop a national strategy for the integration of sleep and circadian rhythms into public health and policies in Canada. The objective of th...
Poster
Full-text available
Introduction Commercially available smartphone apps that claim to improve sleep quantity and/or quality represent an ever-evolving and fast-growing market. Although a large body of work has validated the performance of sleep tracking technologies, there is little information regarding potential sleep enhancement technologies. Our study systematical...
Chapter
In this chapter, we describe the main hypothesized pathways by which the built environment affects sleep health. These pathways can be grouped into three broad categories: ambient hazards and physical exposures; psychosocial pathways; health and behavior. These pathways by which the built environment can affect sleep can occur at three different le...
Article
During the early days of the pandemic and in the context of a seemingly unknown global threat, several potential major sleep disruptors were identified by sleep researchers and practitioners across the globe. The COVID-19 pandemic combined several features that, individually, had been shown to negatively affect sleep health in the general populatio...
Article
Introduction Innovations in consumer sleep technologies have risen exponentially and providers struggle to keep up with patient expectations in this arena. Although there is high quality data on the validity on commercial sleep monitoring devices, there has been a rise in devices for the explicit purpose of sleep enhancement. We sought to identify...
Article
Introduction The ever-evolving market for sleep technologies far outpaces the ability of providers to understand and counsel patients about developments in this area. Although significant literature has validated the performance of sleep tracking technologies, there is little evidence regarding sleep enhancement technologies. Our study systematical...
Article
Introduction: We determined if actigraphy-derived sleep patterns led to 7-year cognitive decline in middle-aged to older Hispanic/Latino adults. Methods: We examined 1035 adults, 45 to 64 years of age, from the Hispanic Community Health Study/Study of Latinos. Participants had repeated measures of cognitive function 7 years apart, home sleep apn...
Article
Study Objectives Sleep-wake complaints and difficulties in making new learning are among the most persistent and challenging long-term sequelea following moderate-severe traumatic brain injury (TBI). Yet, it is unclear whether, and to what extent, sleep characteristics during the chronic stage of TBI contribute to sleep-wake and cognitive complaint...
Article
Background: The impact of sleep disorders on active duty Soldiers' medical readiness is clinically significant. Sleep disorders often present high comorbidity with disease states impacting readiness ranging from obesity and drug dependence. Patient data generated from military health databases can be accessed to examine such relationships. The cur...
Article
The Coronavirus Disease 2019 (COVID-19) pandemic has dramatically impacted the lifestyle of individuals across the globe. In many countries, nationally instituted shelter-in-place orders and closures of non-essential businesses have left many without employment and have forced others to work from home. These policy shifts have changed or removed th...
Article
Full-text available
Purpose Information on access and adherence to positive airway pressure (PAP) treatment is lacking at the regional level in Latin America. This study characterized access and adherence to PAP in patients with moderate-severe obstructive sleep apnea (OSA) in Latin America. Methods Cross-sectional study, conducted at 9 sleep centers across Argentina...
Article
Full-text available
Introduction Few studies have evaluated objective sleep measures and longitudinal neurocognitive decline, particularly in middle-age or Hispanic/Latino adults. We evaluated prospective associations between actigraphy-defined sleep and 7-year neurocognitive change among Hispanic/Latino adults. We hypothesized that sleep duration would be associated...
Article
Introduction The impact of sleep disorders on active duty Soldiers’ medical readiness is clinically significant. Sleep disorders present high comorbidity with disease states directly impacting medical readiness, ranging from musculoskeletal injury (MSK-I), obesity, and drug dependence. The current study performed a risk assessment of sleep disorder...
Preprint
Full-text available
Objective: We constructed research camps at single-effort ultramarathons (50 and 100 miles) in order to study human endurance capabilities under extreme sleep loss and stress. It takes > 24h, on average, to run 100 miles on minimal sleep, allowing us to construct 24h human performance profiles (HPP). Methods: We collected performance data plotted a...
Article
Study objectives: The purpose of the present study was to assess the extent to which sleep extension followed by sleep deprivation impacts performance on an attentional task with varying cognitive and attentional demands that influence decisions. Methods: Task performance was assessed at baseline, after one week of sleep extension, and after 40...
Article
Full-text available
Objectives: The objective of the study was to describe working and sleep conditions and to assess how sleep opportunities are associated with obtained sleep and alertness, in a sample of long-haul bus drivers working with a two-up operations system. Methods: Measures of subjective sleep and sleepiness, actigraphy, circadian temperature rhythm, a...
Article
Objective: Individuals vary in response to sleep loss: some individuals are "vulnerable" and demonstrate cognitive decrements following insufficient sleep, while others are "resistant" and maintain baseline cognitive capability. Physiological markers (e.g., genetic polymorphisms) have been identified that can predict relative vulnerability. Howeve...
Article
Full-text available
Objective: We constructed research camps at single-effort ultramarathons (50 and 100 miles) in order to study human endurance capabilities under extreme sleep loss and stress. It takes > 24h, on average, to run 100 miles on minimal sleep, allowing us to construct 24h human performance profiles (HPP). Methods: We collected performance data plotte...
Article
Sleep loss is a widespread phenomenon and a public health threat. Sleep disorders, medical conditions, lifestyles, and occupational factors all contribute to insufficient sleep. Regardless of the underlying cause, insufficient sleep has well-defined consequences and the severity of said consequences partially influenced by individual characteristic...
Article
Full-text available
During Antarctic isolation personnel are exposed to extreme photoperiods. A frequent observation is a sleep onset phase delay during winter. It is not known if, as a result, daytime sleeping in the form of naps increases. We sought to assess sleep patterns - with focus on daytime sleeping - and alertness in a Latin American crew overwintering in Ar...
Poster
Introduction Threat-related information is preferentially processed, facilitating quick and efficient response. However, the impact of sleep loss or extension on perception of and response to threatening information is not well known. While sleep loss has been found to increase amygdalar activity and negative mood, potentially facilitating threat p...
Article
Full-text available
Objective/Background It is widely established that insufficient sleep can lead to adverse health outcomes. Paradoxically, epidemiologic research suggests that individuals who report habitual nightly sleep greater than 9 h also are at risk for adverse health outcomes. Further, studies have shown that long sleepers have decreased activity levels, whi...
Article
Full-text available
Introduction Sleep loss is ubiquitous in military settings, and it can be deleterious to cognitive, physiological, and operational functioning. This is especially true in the military operational context (e.g., training, garrison, combat) where continuous operations prevent adequate time for rest and recuperation. Furthermore, even when servicememb...
Article
Background The relationship of poor sleep patterns to the increased risk of obesity has been reported, but the results are variable. This study evaluated the association between objectively measured sleep patterns and obesity in a representative adult population of Hispanic/Latino subjects living in the United States. Methods This cross-sectional...
Article
Objective: Investigate the immediate and residual impacts of sleep extension in tactical athletes. Methods: A randomized controlled trial (Sleep extension = EXT vs Control = CON) was conducted on 50 (EXT: 20.12 ± 2.01 years vs CON: 19.76 ± 1.09 years) tactical athletes enrolled in the Reserve Officers' Training Corps (ROTC). Participants wore ac...
Article
Full-text available
Objective To assess the effects of one week of sleep extension on mood, fatigue and subjective sleepiness in normal-sleeping young adults. Methods Twenty-seven adults (age 24.4±5.4 years, 11 female) participated. At-home baseline sleep/wake patterns were recorded with wrist actigraphy for 14 days. This was followed by two nights of in-lab baseline...
Article
Objective: To examine habitual sleep health and investigate how habitual sleep duration impacts performance and motivation in Reserve Officers' Training Corps (ROTC) tactical athletes. Design: Observational. Setting: A large, state university. Participants: Fifty-four young tactical athletes enrolled in ROTC. Measurements: Participants wor...
Article
Objectives: Describe sleep duration in adult Sri Lankans and determine the bias and agreement of self-report and actigraphic assessments. Design: Validation sub-study nested within the Colombo Twin and Singleton Study (2012-2015). Setting: Colombo, Sri Lanka. Participants: 175 adults with actigraphy, randomly selected from 3497 participants with se...
Article
Full-text available
Introduction: The most effective treatment for moderate to severe obstructive sleep apnea (OSA) is continuous positive airway pressure (CPAP) but adherence may be a limiting factor. Most compliance studies often only include patients under CPAP treatment, neglecting the importance of access to treatment. The aim of this study was to evaluate CPAP a...
Article
Objectives: To describe the hours of service provisions in continental Latin America. Design: Information on regulations of service hours was extracted from either the national transportation authorities or ministries of transportation (or the equivalent institution) from each country. Setting: Seventeen sovereign countries in continental Lati...
Poster
Full-text available
Introduction The Profile of Mood States (POMS) scale is a validated measure that assesses changes in mood across different domains. Sleep deprivation studies in particular have shown increases in negative mood subscales of the POMS. In contrast, sleep extension studies have shown improvement in vigor and fatigue. However, to our knowledge, mood cha...
Poster
Introduction Previous research has revealed that some pathologies display exaggerated bias towards threatening stimuli, particularly in individuals with anxiety and trauma related disorders compared to normal controls. Sleep loss is often associated with negative changes in mood and emotional control. The dot-probe task is a hallmark behavioral mea...
Article
Purpose Information on access and adherence to positive airway pressure (PAP) treatment is lacking at the regional level in Latin America. This study characterized access and adherence to PAP in patients with moderate-severe obstructive sleep apnea (OSA) in Latin America. Methods Cross-sectional study, conducted at 9 sleep centers across Argentina,...
Article
Study objective: To assess the extent to which objective sleep patterns vary among U.S. Hispanics/Latinos. Methods: We assessed objective sleep patterns in 2,087 participants of the Hispanic Community Health Study/Study of Latinos from six Hispanic/Latino subgroups aged 18-64 years who underwent 7 days of wrist actigraphy. Results: The age- an...
Article
Study objectives: To investigate cross-sectional associations of neighborhood social environment (social cohesion, safety) with objective measures of sleep duration, timing and disturbances. Methods: A racially/ethnically diverse population of men and women (N=1949) aged 54-93 participating in the Multi-Ethnic Study of Atherosclerosis Sleep and...
Article
Full-text available
Background: There has been growing interest in understanding how neighborhoods may relate to cardiovascular risk. Neighborhood effects on sleep apnea may be one contributing mechanism. We investigated whether neighborhood walking environment and personal activity levels are related to obstructive sleep apnea. Methods: We analyzed data from a sub...
Article
Objectives: We sought to assess the impact of feelings of safety in one's neighborhood and home on sleep quality and sleep duration. Design: The design is a cross-sectional survey using face-to-face interviews, as part of the Argentine Social Debt Observatory assessment. Setting: The setting is a nationwide data from Argentina. Participants:...
Conference Paper
Full-text available
The unprecedented urban growth in face of increasing poverty and so-cial inequity in developing countries is posing an immense challenge at all levels. The urbanization of poverty is reflected mainly by the proliferation and expansion of slums. Over one billion people (about 14 percent of the world population) are slum dwellers. According to UN-HAB...
Article
Full-text available
The Mars500 project was conceived to gather knowledge about the psychological and physiological effects of living in an enclosed environment during 520 d as would be required for a real mission to Mars. Our objective was to investigate the circadian profile of heart rate variability (HRV) in the context of the Mars500 study. Before, during, and aft...

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Projects (5)