Guido Flamini

Verified

Guido verified their affiliation via an institutional email.

Learn more

Verified

Guido verified their affiliation via an institutional email.

Learn more

• Pharmacy
• Full Professor at University of Pisa

Essential oils (EOs) are increasingly recognized as eco-friendly alternatives to synthetic pesticides due to their biodegradability and reduced risks to non-target species. This study investigates the bioactivity of 30 EOs on Rhyzopertha dominica, a major pest of stored grains, with a focus on their repellency and attractiveness across varying conc...

this study represents the first investigation of the volatile composition of Calystegia silvatica (Convolvulaceae) collected in algeria, using headspace solid-phase microextraction and gas chromatog-raphy/mass spectrometry (HS-SpmE-GC/mS). this technique allowed the identification of 44 compounds, constituting 96.9% of the total components. these c...

Industrial hemp (Cannabis sativa L.) is a versatile and sustainable multipurpose plant for agroecology services and a zero-waste circular economy. While the focus has traditionally been on primary products like fiber and seeds, nowadays there is an increasing awareness of the potential value of the by-products generated during hemp cultivation and...

This study investigates the phytochemical profiles and antioxidant properties of three lavender essential oils (LEOs) from Lavandula angustifolia subsp. pyrenaica (DC.), Lavandula x intermedia Emeric ex Loisel cv Grosso, Lavandula x intermedia Emeric ex Loisel cv Super, and compares them to a commercial one. LEOs were extracted by hydrodistillation...

The essential oils (EOs) isolated from fresh leaves, roots, and flowers of Ambrosia polystachya DC. growing in Tunisia were analysed by GC/MS. Twenty-four compounds were identified in the leaf EO, with β-caryophyllene (27.7%), germacrene D (27.1%), and borneol (11.4%) as the main compounds. In the root EO, nineteen compounds were identified, among...

The mosquito Aedes albopictus is a vector of several harmful viruses, necessitating the development of safer and more sustainable repellents than DEET. This study evaluated the potential of plant-based EOs extracted via steam distillation from Aloysia citrodora and Bursera graveolens plants harvested in Ecuador. A. citrodora EO exhibited a high sen...

Stored grain pests like Sitophilus oryzae pose significant challenges to food security and quality, necessitating eco-friendly pest management strategies. This study investigates the combined efficacy of reduced doses of diatomaceous earth (DE) and basil (Ocimum basilicum L.) essential oil (EO) as an alternative to conventional pesticides. Laborato...

Spices and aromatic herbs are important components of everyday nutrition in several countries and cultures, thanks to their capability to enhance the flavor of many dishes and convey significant emotional contributions by themselves. Indeed, spices as well as aromatic herbs are to be considered not only for their important values of antimicrobial a...

Hydroethanolic extracts of coriander seeds (CE), garlic bulbs (GE), and their combina-tion (CGE), were chemically profiled using HS-SPME/GC–MS and LC-Q-TOF/MS–MSto assess volatile composition and to study phenolic molecules, respectively. Biologicalassays were conducted through in vitro and in vivo experiments to measure the EC50of the antioxidant...

Hydroethanolic extracts of coriander seeds (CE), garlic bulbs (GE), and their combination (CGE), were chemically profiled using HS‐SPME/GC–MS and LC‐Q‐TOF/MS–MS to assess volatile composition and to study phenolic molecules, respectively. Biological assays were conducted through in vitro and in vivo experiments to measure the EC50 of the antioxidan...

In this study, we have analysed the Amazonian variety EETP801 Cacao, grown under sustainable organic conditions, in comparison to CCN51 cacao grown on a neighbouring commercial farm using standard practices and an European commercial cacao powdered beverage. The overall metabolite profile was analysed by high performance TLC analyses (HPTLC), the v...

Microorganisms play a crucial role in addressing the challenges related to the increasing detrimental effects of intensive agriculture in vineyards by contributing to various aspects, from maintaining soil health and vine vitality to influencing fermentation and the overall wine features. Among microorganisms, mycorrhizal fungi are widely distribut...

The essential oils (EOs) from nine species (Artemisia campestris, A. herba-alba, Juniperus foetidissima, Laurus nobilis, Mentha pulegium, M. spicata, Rosmarinus officinalis, Salvia officinalis, and Thymus vulgaris) of the Algerian flora have been hydrodistilled, analysed, and tested for their antioxidant and antiproliferative properties. A. campest...

Recently, there has been significant exploration into the utilization of food by-products as natural reservoirs of bioactive substances, particularly in the creation of functional foods naturally enriched with antioxidants. Citrus peels represent a viable option for formulating enhanced olive oils that contribute to a healthier diet, due to their b...

The impact of germination and milling on volatile compounds (VOCs) of chickpea cultivar was evaluated using HS-SPME/GC-MS technique. In total, 35 VOCs were identi ed. In this study, 28 active odors were characterized in seeds and 23 in ours: 17 in raw seeds, 24 in sprouted grains, 21 in raw ours, and 17 in germinated ours; they accounted for 98.9,...

The aim of this study is to develop a nanoemulgel encapsulating a Tunisian Prickly Pear (Opuntia ficus-indica L.) seed oil (PPSO) to assess, for the first time, the in vivo efficacy of this nanoformulation on wound healing. Phytocompounds of this oil have been reported in the literature as having powerful pharmacological activities. However, it rem...

Cannabis sativa L. essential oil has attracted the interest of the scientific community thanks to its numerous biological activities. Several studies have evaluated EOs as alternative therapeutic approaches to limit the use of antibiotics; the present study aimed to evaluate the in vitro inhibitory and bactericidal activity of the essential oils ob...

The healthy properties of bee pollen mainly depend on the botanical, geographical origin and storage conditions. This study aimed to characterise the composition of volatile compounds and describe the sensory profile of Tuscan bee pollens collected in two different areas in the same period and stored for six months under different conditions. The h...

As societies undergo shifts in dietary patterns, there is often an increase in nutrition‐related issues. This is particularly evident in the case of wheat bakery products, which have evolved in an unsustainable way. The fortification of wheat flour with vegetables has emerged as a strategy to mitigate the imbalanced composition of white bread. The...

The phytochemical profile of essential oils is influenced by genetic and paragenetic factors. In this research, we studied the essential oils of Lavandula angustifolia and Lavandula x intermedia cultivated in Lebanon. The latter is a cross hybrid between Lavandula angustifolia and Lavandula latifolia and is also known as lavandin and Lavandula hybr...

Daucus genus (Apiaceae) comprises economically relevant plants distributed in temperate regions. These plants are used mainly as food but are also known for their biological properties. Here, the essential oils (EOs) obtained by hydro-distillation of roots and stems of D.sahariensis Murb. growing in Algerian Sahara were studied by GC-MS analysis. F...

The chemical compositions of the essential oils of Pittosporum tobira organs and of the volatile organic compounds emitted were identified. The EOs are extracted by hydrodistillation and the VOCs by head space. The main EOs compounds are α‐neoclovene, β‐caryophyllene and limonene in roots. Viridiflorol in young stems, flowers and young leaves (34.9...

Trigonella foenum-graecum L. commonly known as fenugreek, is an important economic and medicinal plant cultivated in various regions of the world. Fenugreek produces several important active chemical constituents that determine its pharmacological properties. The aim of this research was to analyze the volatile constituents spontaneously emitted by...

As synthetic insecticides cause many adverse effects, plant-based materials, mainly essential oils, are becoming popular as safer alternatives. It is in this context that the current study was included to show for the first time the chemical profiles and the insecticidal efficacy of Ferula tunetana (F. tunetana) leaf (LEO) and stem (SEO) essential...

Passiflora foetida is a climbing herb employed in ethno-medicine for the treatment of various ailments. The essential oil from flowers of P. foetida was obtained by hydrodistillation. The ethanol extract of the leaves was dissolved in water, then partitioned with n-hexane and n-butanol to obtain the various fractions; the fractions and isolated com...

The seeds of Opuntia sp. require additional investigations because they could contain several active molecules. Therefore, the present study analyzed the chemical composition and biological activities of Opuntia microdasys and that of Opuntia macrorhiza using in vitro and in vivo models. The headspace of the powders of the seeds of Opuntia have bee...

In this work, we investigated aroma volatiles emanated by dry roots, stems, leaves, flowers, and fruits of Cardaria draba (L.) Desv. growing wild in Tunisia and its aerial part essential oils (EOs) composition. A total of 37 volatile organic compounds (96.7%–98.9%) were identified; 4 esters, 4 alcohols, 7 hydrocarbons, 12 aldehydes, 5 ketones, 1 la...

This The cactus pear is belongs to the Cactaceae family Opuntia. The cladodes are known as nopalitos, are frequently consumed and used in folk medicine due to their beneficial effects and phytochemical composition. Cactus in Tunisia is mostly localized in areas characterized by low quality soils and water scarcity. In this study we evaluate the amo...

The complex dynamics between oxygen exposure, sulphur dioxide (SO2) utilization, and wine quality are of the utmost importance in wine sector, and this study aims to explore their fine balance in winemaking. As a common additive, SO2 works as an antiseptic and antioxidant. However, its excessive use has raised health concerns. Regulatory guidelines...

The resin essential oil (REO) of Araucaria heterophylla trunk bark was investigated for its chemical composition. Then, it was evaluated for its insecticidal and allelopathic activities. The REO was obtained by hydrodistillation for 9 h (yield of 4.2% w/w). Moreover, fractional hydrodistillation was carried out at 3-hour intervals, resulting in 3 f...

Sitophilus oryzae (L.) (Coleoptera: Dryophtoridae) represents one of the most important pests of stored products. The adults are considered very effective packaging penetrators, causing serious economic losses. Hence, the development of new food packaging technologies is crucial to prevent its infestations. In this study, Citrus × aurantium L., Ele...

Cutaneous myiasis is a severe worldwide medical and veterinary issue. In this trial the essential oil (EO) of the Andean medicinal plant species Clinopodium nubigenum (Kunth) Kuntze was evaluated for its bioactivity against the myiasis-inducing blowfly Lucilia sericata (Meigen) (Diptera Calliphoridae) and compared with that of the well-known medici...

This study explores a nanoemulsion (NE)-based gel incorporating Tunisian Pituranthos tortuosus essential oil, with a focus on its wound-healing potential. The essential oil, extracted via hydrodistillation, underwent GC-MS analysis for compositional verification. The physicochemical characterization included dynamic light scattering (DLS), transmis...

Bupleurum plantagineum Desf. (Apiaceae) is a plant endemic to North Africa, including Algeria. It is used as natural medicine, due to its anti-inflammatory, antioxidant and hepatoprotective properties. In this work, we studied the chemical composition of the essential oil (EO) obtained by hydro-distillation from B. plantagineum leaves collected fro...

Aromatic plant essential oils (EOs) represent a promising alternative to synthetic compounds for humans, food and crop protection from insect pests. However, although many studies have demonstrated the toxic and repellent effect of EOs against harmful insects, some studies indicate that EOs can act, on the contrary, as attractants for harmful insec...

Industrial hemp (Cannabis sativa L.), being a multiharvest crop, can increase farm profitability and cropping system diversification, including in marginal areas. Since inflorescence essential oil (EO) represents a valuable co-product for cosmetics and pharmaceutical sectors, the aim of this study was to assess the effect of pedoclimatic conditions...

This study is the first to explore the essential oil of Ononis angustissima Lam. subsp. filifolia Murb., a subspecies growing in the Algerian northeastern Sahara. The chemical composition was evaluated by GC/GC-EIMS. Antioxidant activity was evaluated using two methods. Thirty-four (91.6%) individual components were identified. The main constituent...

This research aimed to evaluate for the first time the chemical composition and antioxidant potential of volatile fraction and different concentrates obtained from Acanthus mollis L.. The volatile components from the aerial parts of A. mollis were extracted by hydrodistillation and analyzed by GC-MS. Twenty-four compounds were characterized, repres...

This study focuses on different chemo-types of Tunisian Eucalyptus essential oils (EOs) and their potential for controlling aphids, phytopathogenic fungi, weed germination and seedling growth. The EOs, obtained from Eucalyptus astringens (Maiden) Maiden and Eucalyptus lehmannii (Schauer) Benth. leaves through hydrodistillation, were analyzed using...

In recent years, essential oils (EOs) have received interest due to their antibacterial properties. Accordingly, the present study aimed to investigate the effectiveness of the EOs obtained from seven species of Salvia on three strains of Listeria monocytogenes (two serotyped wild strains and one ATCC strain), a bacterium able to contaminate food p...

This study represents the first investigation of the chemical composition and the antioxidant and antimicrobial activities of Ononis aurasiaca Förther & Podlech, a plant species endemic to the Aures Mountains of Algeria. The essential oil of the plant aerial parts was analysed using GC-MS. The in vitro antioxidant activity was evaluated using three...

The volatile compounds of Vicia faba. L var. minor and var. major seeds were evaluated by headspace-solid phase micro-extraction (HS-SPME) coupled to gas chromatography-mass spectrometry (GC-MS). The total identification percentages of the extracted volatiles were 95.5% and 98.3%, respectively. The number of aroma compounds detected was 28. Among t...

Aphids (Aphidoidea) and Fusarium spp. are widely recognized as destructive pests that cause significant damage to crops on a global scale. This study aimed to ascertain the chemical composition of essential oils (EOs) of four Tunisian Eucalyptus species and evaluate their toxicity against common aphids and phytopathogenic fungi. The EOs were obtain...

To our knowledge, this study represents the first investigation into the chemical composition of the essential oil of Euphorbia guyoniana Boiss. et Reut., a rare spontaneous species found in the sand dunes of Algeria. The essential oil was analyzed using gas chromatography-flame ionization detector and gas chromatography-electron impact mass spectr...

The following study presents the constituents of the volatile oils found in the leaves and seeds of Indigofera tinctoria , as well as the secondary metabolites of its leaves crude fractions. The insecticidal activities of these fractions against Sesamia calamistis were also evaluated. The volatile oils from the leaf and seed of Indigofera tinctoria...

Pallenis spinosa (L.) Cass. is a widespread plant in the Mediterranean region. Traditionally, it is used as a medicinal species to treat several ailments, from inflammation to skin injuries. Although the phytochemical content of this plant has already been investigated, there is currently limited data on Algerian P. spinosa. In this work, we focuse...

This study investigated the effect of chitosan (CHT) incorporated with essential oils (EOs) from three plants: Laurus nobilis L. (bay leaf), Piper nigrum L. (black pepper), and Cinnamomum verum J. Presl (cinnamon) on fresh foods. A panel of expert sensory analysts selected the best EO olfactory profile to be used with cheese and cured meat. The com...

Olive oil, rich in bioactive compounds and antioxidants, is renowned for its health benefits. The lipoxygenase pathway contributes to the formation of antioxidant metabolites in virgin olive oils. This study examined the impact of location on volatile compounds, fatty acids, and antioxidants in Chétoui monovarietal olive oil from thirteen Tunisian...

This study develops an efficient, low-temperature process for formulating a nanoemulsion-based gel encapsulating Pituranthos tortuosus's essential oil, investigating its wound healing potential. The novel process ensured stable encapsulation of the medicinal plant's oil. The nanoemulsion was characterized using dynamic light scattering and transmis...

Medicinal plants produce several natural bioactive molecules and compounds called secondary metabolites that have very important biological properties. The objective of this work is to determine the chemical composition of essential oils (EO) obtained from the leaves of three Tunisian species of Eucalyptus (E. oleosa, E. pimpiniana, E. polyanthemos...

Wild Vitex agnus-castus (VAC) is a Mediterranean plant that is rich in bioactive metabolites. This study aimed to validate, for the first time, the beneficial use of VAC fruits and fruit decoctions (VFDs) through in vitro and in vivo trials. Forty-one volatile components were detected in VAC fruits, with 1,8-cineole (30.3%) comprising the majority....

Introduction: The Increase in cancer deaths has raised concerns among scientists to research on prospective anticancer agents. Lannea egregia was selected for this research because it has been identified to have ethnobotanical claims in relation to the cure of cancer in South-West Nigeria. Aims: To analyze the chemical constituents and determine th...

The goal of this work was to investigate the impact of the flavoring of some aromatic plants/spices, including rosemary (R), lemon (L) and orange (O) at the concentration of 5% and 35% (w/w) added by 2 methods (conventional maceration and direct flavoring), on quality attributes, chemical changes and oxidative stability of extra virgin olive oil (E...

Narrowband green (G), blue (B), red (R), and polychromatic (W ‒ R:G:B, 1:1:1) lights were supplemented (250 µmol photon m‒2 s‒1; 5 h d−1; 21 d) to ambient light with Light Emitting Diodes (LED) in green- (‘Tigullio’; TI) and red-leafed (‘Red Rubin’; RR) sweet basil (Ocimum basilicum L.) plants. The aim of this work was to evaluate LED-triggered var...

Many species belonging to the genus Ocimum are used for aromatic, medicinal, and cosmetic purposes. The essential oil (OFEO) obtained by hydrodistillation of the flowering aerial parts of Forsskal’s Basil “Ocimum forskolei Benth” growing in extreme environmental conditions in Mecca Region, Saudi Arabia was analyzed by GC-MS. The main constituents w...

Many plants are able to synthesize essential oils (EOs), which play key roles in defense against weeds, fungi and pests. This study aims to analyze the chemical composition and to highlight the antioxidant, antimicrobial and phytotoxic properties of the EOs from Eucalyptus falcata, E. sideroxylon and E. citriodora growing in Tunisia. EOs were analy...

Rosemary (Rosmarinus officinalis L.) and myrtle (Myrtus communis L.) are perennial herbs, typical of the Tunisian flora, with an intense aromatic flavor. Their essential oils, obtained by hydro-distillation, were analyzed by gas chromatography coupled to mass spectrometry and by infrared Fourier transform spectrometry. In addition, these oils were...

Due to the several side effects of synthetic pesticides, including environmental pollution, threats to human health, and the development of pest resistance to insecticides, the use of alternative healthy, available and efficient agents in pest management strategies is necessary. Recently, the use of essential oil obtained from aromatic plants has s...

The Mediterranean fruit fly, Ceratitis capitata (Wiedemann), is the single most important pest species affecting fresh fruit particularly citrus varieties. Over time, pest control approaches have been chronologically associated with procedures more and more friendly to the environment, starting with the use of insecticides, then sterile insecticide...

Simple Summary Arbuscular mycorrhizal fungi (AMF), as well as ultraviolet-B radiation (UV-B), could act as key factors affecting plant–insect interactions. The stress related to one of these two factors could be balanced by the positive effects of the other. In the present work, the feeding preferences of Myzus persicae aphids for lettuce plants ex...

Consumers’ appreciation of wines is mainly driven by their aroma, which is the most important organoleptic characteristic and key attribute. The volatile bouquet derives from the grape berries and from the processing phases of vinification. In the present study, the volatile emission of six grapevine cultivars has been analysed through four phases...

Meat production has a higher economic and ecological impact than other commodities. The reduction in meat loss and waste throughout the whole supply chain is a demanding challenge. In recent years, the interest in the food-grade polysaccharide chitosan (CH) and essential oils (EOs) employed as allies in meat protection has increased. In this work,...

The Nemo’s Garden® project is an alternative production system for areas with scarce cultivable land but significant presence of water; thus, it is an interesting intervention to address the climate crisis. This work aimed to evaluate the micromorphological, biochemical, and phytochemical characteristics of Stevia rebaudiana (Bertoni) Bertoni grown...

We replaced a % of white wheat flour with swiss chard (Beta vulgaris) powder and examined the impact on bread’s nutritional quality and on consumers’ preference. As expected, the mainstream refined flour was depleted of minerals and chard addition may complement such deficiencies; Moreover, chard may supply phytonutrients (with anti-oxidant, anti-i...

Olive leaves are rich in antioxidant compounds. During harvest, they reached about 10% of the total weight which can affect the olive oil quality. So, this work aimed to study the effect of adding different amounts of leaves (1, 2, 5, 10 and 20%) during the olive oil extraction of cv. Chemlali. Changes in physico-chemical indices, oil stability, fa...

Comparative chemical analyses among peel and pulp essential oils (EOs) and methanolic extracts of four Citrus australasica varieties (Red, Collette, Pink Ice, and Yellow Sunshine), and the hybrid Faustrime, were performed using GC-MS and UHPLC-DAD-HR-Orbitrap/ESI-MS. Peel and pulp extracts were also analysed for their in vitro antioxidant activity...

Millettia thonningii has been used in folk medicine for centuries to treat pains, pathogenic diseases, and radical-induced aliments. Essential oils (EOs) are a source of bioactive compounds, and their potential application as an alternative to synthetic products in the treatment of infectious diseases and oxidative stress has been validated. Leaf,...

The volatile profiles of raw, dehulled, and germinated seeds and flours of green and brown lentils (Lens culinaris subsp. culinaris) were assessed using headspace solid-phase micro-extraction coupled to gas chromatography-mass spectrometry (HS-SPME-GS-MS). The total identification percentages of the extracted volatiles ranged between 96.3% and 99.8...

Few studies have investigated at the same time how physicochemical, volatile, and sensory characteristics affect coffee liking. The aim of this study is to evaluate the influence of geographical origin and variety on physicochemical parameters and volatile compounds composition of mono‐origin and mono‐variety coffees. Check‐all‐that‐apply (CATA) me...

Fruits from the same cultivar of Olea europaea L. cv. Chaaibi were picked at the same ripeness stage and processed quickly across varied environmental conditions in Tunisia. Solid-phase micro-extraction (SPME) coupled with gas chromatography–mass spectrometry (GC–MS) were used to determine the aroma profile of virgin olive oils. The volatile profil...

Clinopodium candidissimum (Munby) Kuntze (Lamiaceae) is used in traditional medicine and as a food condiment in Algeria, where it is known as Zaater cheleuh and Nabta elbida. Here, we report the comprehensive characterisation of non-volatile polar constituents extracted from C. candidissimum aerial parts (a mixture of inflorescences, stems and leav...