Grigorios Kotronoulas

• PhD, MSc (Cancer Care), PGCAP, RETF, BSN, RN
• Reader in Cancer Survivorship at University of Glasgow

Background Nurses are well positioned to identify the most critical issues in patient care and to determine priorities for investigation. Involving nurses in developing research priorities may increase their engagement in research and enhance the development high-quality nursing practice. Aim This study aimed to scope the potential topics for futu...

PURPOSE The adoption of artificial intelligence (AI) in health care may afford new avenues for personalized and patient-centered care. This systematic review explored the role of AI in symptom monitoring for adult cancer survivors. METHODS A comprehensive search was performed from inception to November 2023 in seven bibliographic databases and thre...

Objective Palliative thoracic radiotherapy is a key treatment option for symptom management in advanced lung cancer. Continuous symptom monitoring is critical to ensuring optimal therapeutic outcomes and preserving patients’ well-being. This systematic review aimed to explore patients’ symptom experiences during palliative thoracic radiotherapy for...

BACKGROUND Patients receiving chemotherapy require ongoing symptom monitoring and management to optimize their outcomes. In recent years, digital remote monitoring interventions have emerged to provide enhanced cancer care delivery experiences to patients and clinicians. However, patients and clinicians evaluations of these technologies are rare. T...

Background Patients receiving chemotherapy require ongoing symptom monitoring and management to optimize their outcomes. In recent years, digital remote monitoring interventions have emerged to provide enhanced cancer care delivery experiences to patients and clinicians. However, patient and clinician experiential evaluations of these technologies...

Background Worldwide, bladder cancer (BC) has been regarded as the tenth most common cancer with more than 573 000 new cases in 2020. This research presents a systematic review and meta-analysis of studies examining the quality of life (QOL) among patients with BC. Methods The study was designed according to Preferred Reporting Items for Systemati...

Breast cancer is now the most commonly diagnosed cancer worldwide. Approximately 30% of those who present with early breast cancer later develop advanced breast cancer (ABC). Additionally, approximately 6% have advanced breast cancer at diagnosis. New treatment options result in an extended lifespan dominated by cycles of deterioration and stable d...

BACKGROUND Interest in the application of predictive risk models (PRMs) in healthcare to identify people most likely to experience disease and treatment-related complications is increasing. In cancer care, these techniques are focused primarily on prediction of survival or life-threatening toxicities (e.g. febrile neutropenia). Fewer studies focuse...

Background Interest in the application of predictive risk models (PRMs) in health care to identify people most likely to experience disease and treatment-related complications is increasing. In cancer care, these techniques are focused primarily on the prediction of survival or life-threatening toxicities (eg, febrile neutropenia). Fewer studies fo...

Penelitian ini adalah salah satu bagian dari 3 projects Post-stroke cognitive impairment studies. Studi tahap satu dengan cakupan data tata laksana stroke dari seluruh dunia dan studi tahap 2 kuantitatif di Indonesia telah selesai dilaksanakan

Penelitian ini adalah salah satu bagian dari 3 projects Post-stroke cognitive impairment studies. Studi tahap satu dengan cakupan data tata laksana stroke dari seluruh dunia dan studi tahap 2 kuantitatif di Indonesia telah selesai dilaksanakan

Objectives To navigate the field of digital cancer care and define and discuss key aspects and applications of big data analytics, artificial intelligence (AI), and data-driven interventions. Data Sources Peer-reviewed scientific publications and expert opinion. Conclusion The digital transformation of cancer care, enabled by big data analytics,...

Objectives: LifeChamps is an EU Horizon 2020 project that aims to create a digital platform to enable monitoring of health-related quality of life and frailty in patients with cancer over the age of 65. Our primary objective is to assess feasibility, usability, acceptability, fidelity, adherence, and safety parameters when implementing LifeChamps...

The COVID-19 response introduced legal restrictions on social distancing globally, affecting healthcare staff personally and professionally. These restrictions suspended routine hospital visiting, which may have left staff feeling they had to compromise on the care they provided. Such conflict may be experienced as moral injury. This scoping review...

Purpose: Identifying cancer nursing research priorities is central to influencing the direction of cancer care research. The aim of this rapid review was to explore research priorities identified by oncology nurses for cancer care delivery between 2019 and 2022. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analysis info...

Objectives: There is little research to help health care professionals understand what patient outcomes are considered a priority in advanced liver or kidney cancer. Knowing what is important to patients can help promote person-centered approaches to treatment and disease management. The aim of this study was to identify those patient-reported out...

Objectives: To provide an overview of three consecutive stages involved in the processing of quantitative research data (ie, data management, analysis, and interpretation) with the aid of practical examples to foster enhanced understanding. Data sources: Published scientific articles, research textbooks, and expert advice were used. Conclusion:...

Abstract Objectives This article provides practical guidance on developing a comprehensible abstract, including those required for funding applications, conferences, and publication. In addition, we discuss and demonstrate the practicalities of editing and revising an abstract for conference or peer review and identify emerging formats that may be...

Background: Specialist nursing care is a core indicator of quality care for people living with advanced breast cancer. However, access to and quality of nurse education programmes in advanced breast cancer is variable. Objectives: This study aims to define the topics for inclusion in an international curriculum for an advanced breast cancer educ...

Objectives: To present a comprehensive overview of key constructs of experimental and nonexperimental quantitative research, drawing on one example case from cancer care. Data sources: Published scientific articles, research textbooks, and expert advice were used in this article. Conclusion: Quantitative research turns information collected ab...

Purpose This study is to evaluate healthcare needs, preferences, and expectations in supportive cancer care as perceived by cancer survivors, family caregivers, and healthcare professionals. Methods Key stakeholders consisted of cancer survivors diagnosed with breast cancer, prostate cancer, or melanoma; adult family caregivers; and healthcare pro...

Background Patient-reported outcomes (PROs) are key indicators of health status and functioning, coming directly from the patient. Comprehensive monitoring of PROs enables implementation of person-centred care. Currently, the PROs that patients with advanced renal cell carcinoma (RCC) or hepatocellular carcinoma (HCC) consider of greatest importanc...

Objective Family caregivers in West Java, Indonesia, care for their family members at home or in a shelter with limited sources. This study aims to establish the needs of family caregivers when providing informal care to family members with cancer in the resource-challenged context of West Java, Indonesia Data Sources This cross-sectional survey i...

Workplace violence against nurses is an international public health issue with likely detrimental consequences for individuals, systems and societies. To effectively address workplace violence against nurses, its root causes must be understood and its effect on nurse outcomes quantified. In line with Preferred Reporting Items for Systematic Reviews...

Objectives To discuss potential benefits, challenges, and opportunities of integrating patient-reported outcome measures in geriatric oncology, with the goal being to advance patient screening for ‘functional fitness for treatment.’ Data Sources This is narrative review of the relevant literature using PubMed. Conclusion Patient screening in geri...

Objective To evaluate effects of remote monitoring of adjuvant chemotherapy related side effects via the Advanced Symptom Management System (ASyMS) on symptom burden, quality of life, supportive care needs, anxiety, self-efficacy, and work limitations. Design Multicentre, repeated measures, parallel group, evaluator masked, stratified randomised c...

Background Patients hospitalised with COVID-19 have increased morbidity and mortality, which requires extensive involvement of specialist Hospital Palliative Care Teams. Evaluating the response to the surge in demand for effective symptom management can enhance provision of Palliative Care in this patient population. Aim To characterise the sympto...

Purpose Self-management interventions (SMIs) are designed to empower people living beyond breast cancer and help them adjust to a new normal. This structured review aimed to critically appraise and synthesise up-to-date evidence on the effectiveness of SMIs to promote health-related quality of life (HRQoL) in people with breast cancer in the post-t...

Purpose Problematic polypharmacy can exaggerate “medicine burden” for the patient. Patient-reported outcomes (PROs) are key indicators of medicine burden, and PRO measures (PROMs) can help patients articulate their perceptions of medicine burden. We aimed to: (a) evaluate what PROMs currently exist that assess medicine burden, and what PROs they ta...

Sleep is crucial to children's health and development. Reduced physical activity and increased screen time adversely impact older children’s sleep, but little is known about these associations in children under 5 years. This systematic review examined the association between screen time/movement behaviors (sedentary behavior, physical activity) and...

Background: Sexual health care should be an integral part of holistic, person-centred care for patients with cancer. Nurses can have a pivotal role, but nurse-led care in this context has been historically challenging. Objectives: To update the state of scientific knowledge pertinent to nurses' competencies in delivering sexual health care to pa...

Background: Patients with lung cancer (LC) report lower quality of life (QoL) and higher levels of psychological distress compared with other cancer populations. Lung cancer stigma (LCS) may in part explain these findings. Aim: We investigated the prevalence of patient-perceived lung cancer stigma (LCS) and its relationships to symptom burden/se...

Background: Ensuring adequate knowledge about palliative care and positive attitudes towards death and dying are crucial educational aspects when preparing undergraduate nursing students to respond effectively to the complexities of care for people affected by a progressive, life-limiting illness. In undergraduate nursing education in Greece, the l...

Objectives: To explore healthcare professional perceived barriers and facilitators to discussing sexual health and wellbeing with patients after diagnosis of chronic illness. Methods: Five databases were searched and included data were synthesised using a meta-ethnographic approach. Confidence in findings was assessed using the GRADE-CERQual fra...

Purpose: Developing new supportive/palliative care services for lung cancer should encompass effective ways to promptly identify and address patients' healthcare needs. We examined whether an in-clinic, nurse-led consultation model, which was driven by use of a patient-reported outcomes (PRO) measure, was feasible and acceptable in the identificat...

Close monitoring of chemotherapy toxicity can be instrumental in ensuring prompt symptom management and quality care. Our aim was to develop a brief clinical tool to enable daily assessment of chemotherapy toxicity and investigate/establish its content validity, feasibility/applicability, internal consistency and stability. Development of the Daily...

Introduction: People with cancer are disproportionately affected by disordered sleep. Six in 10 of those recently diagnosed and/or receiving anti-cancer treatment suffer debilitating sleep loss. However, disordered sleep is still typically overlooked and poorly managed in cancer care. Objectives: To introduce health professionals to formal sleep a...

BACKGROUND There has been an international shift in health care, which has seen an increasing focus and development of technological and personalized at-home interventions that aim to improve health outcomes and patient-clinician communication. However, there is a notable lack of empirical evidence describing the preparatory steps of adapting and i...

Background: ASyMS is a mobile‐phone based remote‐monitoring and alert system that enables real‐time monitoring of patients' chemotherapy (CT)–related symptoms. Aims: eSMART aims to evaluate the short‐ and long‐term impact of ASyMS, compared with standard care, on patient reported outcomes and the delivery of care. Additionally, eSMART includes eco...

Objectives: To examine the personal domains multiple mini interviews (MMIs) are being designed to assess, explore how they were determined and contextualise such domains in current and future healthcare student selection processes DESIGN: A systematic review of empirical research reporting on MMI model design was conducted from database inception...

Purpose Living with a melanoma diagnosis can be challenging. We aimed to assess the feasibility, acceptability, and perceived value of a nurse-led intervention that utilised patient-reported outcome (PRO) measures to identify and address the supportive care needs of newly diagnosed patients with Stage I/II melanoma over the first 4 months post-diag...

Close monitoring of chemotherapy toxicity is important. PRO measures need to be brief, valid, easy to use, and allow for daily symptom assessment. We developed a brief clinical tool to enable daily assessments of chemotherapy toxicity. We investigated the tool’s content validity, feasibility/applicability, internal consistency and stability.

Purpose Logistical issues pertinent to the use of patient-reported outcome measures (PROMs) by colorectal cancer nurse specialists (CNS) to identify the needs of people with colorectal cancer (CRC) in acute care remain unknown. We explored the feasibility and acceptability of PROMs-driven, CNS-led consultations to enhance delivery of supportive car...

Purpose/aims: Patient-reported outcome measures (PROMs) can be effectively used to uncover the unmet needs of women with cervical cancer for supportive care. Our aim was to explore the feasibility and acceptability of PROM-driven, nurse-led consultations to enhance delivery of supportive care to women with cervical cancer during active anticancer...

Backgound: ASyMS is a mobile-phone based remote-monitoring and alert system enabling real-time monitoring of patients’ chemotherapy-related symptoms. The eSMART RCT compares patient-reported outcomes (PROs) and delivery of care for patients using ASyMS with those accessing the same Acute Oncology Service through the standard care pathway at each pa...

Purpose: Gaining a clear understanding of the health needs and concerns of people with cancer of the colon and/or rectum can help identify ways to offer a comprehensive care package. Our aim was to systematically assess the relevant literature and synthesise current available evidence. Methods: A systematic review was conducted according to the PR...

Introduction While some evidence exists that real-time remote symptom monitoring devices can decrease morbidity and prevent unplanned admissions in oncology patients, overall, these studies have significant methodological weaknesses. The electronic Symptom Management using the Advanced Symptom Management System (ASyMS) Remote Technology (eSMART) st...

Purpose/Objectives: To explore changes over time in self-efficacy and the predictive ability of changes in state anxiety and health-related quality of life during chemotherapy. Design: Secondary analysis of a longitudinal dataset derived from a larger, multicenter study. Setting: Outpatient oncology clinics across eight general hospitals in England...

Introduction: Logistics pertinent to the use of patient-reported outcome measures (PROMs) by Colorectal cancer nurse specialists (CNS) to identify the unmet needs of people with colorectal cancer (CRC) [1] in the acute care setting remain unknown. Aims/Objectives: We explored the feasibility and acceptability of PROMs-driven, CNS-led consultations...

Introduction Malignant melanoma is now ranked fifth leading cancer in the UK. In spite of this, little is known about the particular needs of this patient population. Negative effects of melanoma include fear of the sun, uncertainty for the future and emotional problems brought on by negative body image. The use of patient-reported outcomes measure...

Introduction: Patient-reported outcome measures (PROMs) can be utilised to effectively identify the needs of women with cervical cancer (CC) for supportive care1. The logistics pertinent to use of needs assessment PROMs by Gynaecology cancer nurse specialists (CNS) in the acute care setting still remain unknown. Aims/Objectives: Our aim was to expl...

Introduction: Disordered sleep is experienced by at least 50% of people affected by cancer [1,2]. Sleep problems may be more than one, persistent and debilitating, but they are often overlooked by oncology clinicians and under-reported by patients/carers [3]. Aims/Objectives: In line with current clinical guidelines [3], our aim is to re-introduce...

Purpose: To examine the trajectories and predictors of state and trait anxiety in patients undergoing chemotherapy for breast or colorectal cancer. Methods: Secondary analysis of data collected as part of a large multi-site longitudinal study. Patients with breast or colorectal cancer completed validated scales assessing their state and trait an...

Purpose/objectives: To longitudinally explore changes, similarities, differences, and interrelations in the sleep-wake parameters of patient-caregiver dyads throughout adjuvant chemotherapy for breast cancer. . Design: Observational, repeated-measures, dyadic study. . Setting: Four ambulatory oncology clinics in Scotland. . Sample: 48 dya...

Background: In recent years, the shift in cancer services from traditional tertiary care to care delivered within communities has increased the need for patients to engage in self-care activities in order to prevent or reduce the severity of numerous and complex-side effects (McCorkle et al., 2011) and make important health decisions when at home i...

The use of technology-enhanced patient-reported outcome measures to monitor the symptoms experienced by people with cancer is an effective way to offer timely care. OBJECTIVE: This study aimed to (a) explore the feasibility and acceptability of the Advanced Symptom Management System with patients with lung cancer receiving radiotherapy and clinici...

The systematic use of patient-reported outcome measures (PROMs) has been advocated as an effective way to standardize cancer practice. Yet, the question of whether PROMs can lead to actual improvements in the quality of patient care remains under debate. This review examined whether inclusion of PROM in routine clinical practice is associated with...

Background: Alterations in habitual sleep/wake patterns (SWP) of women with breast cancer and their informal caregivers may be concurrently exacerbated and co-vary during the patient's treatment. Taking into consideration the complexity of mechanisms interfering with a care dyad's sleep, the current study set out to longitudinally explore SWP of pa...

Purpose: Caregiver burden considerably affects the lives of families providing care to people with advanced cancer. The aim of this study was to validate the Greek translation of the revised Bakas Caregiving Outcomes Scale (BCOS) with a sample of informal caregivers of people with advanced cancer receiving outpatient palliative radiotherapy. Meth...

Background: The use of patient-reported outcome measures is a method of identifying and addressing supportive care needs (SCN) of people with lung cancer, which are often overlooked. Objective: The objectives of this study were to identify and evaluate existing SCN tools previously used in studies with patients with lung cancer and to establish...

Context: Alterations in sleep-wake patterns of care recipients and their informal caregivers are common in the context of a chronic illness. Given the current notion that sleep may be regulated within and affected by close human relationships, concurrent and interrelated sleep problems may be present in care recipient-caregiver dyads. Objectives:...

Introduction People diagnosed with a curable cancer may have a transitory care requirement, often before, during and immediately after treat-ment, whereas those for whom prognosis is less favourable may require long-term palliative care. Whatever the case may be, in their majority people with cancer will rely on families and friends for help and su...

INTRODUCTION Sleep is a vital human process known to be essential for health, well-being, and optimal physical and psychological functioning [1, 2]. It is therefore reasonable to argue that sleep-wake disturbances may have serious consequences on the equilibrium of life [3, 4]. Sleep difficulties have been reported as a frequent complication of and...

BACKGROUND:: Sleep is increasingly recognized as an area of functioning that may be greatly affected in persons who are practically and emotionally involved in the care of patients with cancer. Clinician awareness is required to ensure that effective care for informal caregivers with sleep problems is provided. OBJECTIVE:: A 2-fold critical review...

Complaints of poor nocturnal sleep and daytime dysfunction may be frequent among women receiving chemotherapy for breast cancer. A critical review of the literature was conducted, which aimed at summarising and critically analysing findings regarding sleep in women with early-stage breast cancer across neo-/adjuvant chemotherapy treatment. A system...

Background: Cytotoxic chemotherapy destroys not only cancer cells but also normal healthy cells, leading to the occurrence of multiple side effects, the nature and extent of which depend on several factors. Aim: The purpose of this study was to explore the type and the intensity of the side effects and symptoms produced by anticancer agents. Method...

Quality of sleep in patients with cancer is regarded as of utmost importance. The aim of the present study was to assess psychometric properties and feasibility of the Greek version of the Pittsburgh Sleep Quality Index (GR-PSQI). Following a "forward-backward" procedure, the scale was translated into Greek. The GR-PSQI was administered as a self-r...

Background: Despite advances in medical therapy heart failure consists a prevalent debilitating disease of poor prognosis, strongly associated with high mortality and morbidity rates. On the same time, depression rates are higher in patients with heart failure than in the general population. Depression may be underdiagnosed and consequently undertr...

Sleep is an essential ubiquitous biological process, a periodical state of quiescence in which there is minimal processing of sensory information and no interaction with conspecifics or the environment. Despite relevant research on sleep structure and testing of numerous endogenous sleep-affecting chemicals, questions as to the precise mechanisms a...

The experience of living with cancer is associated with a variety of consequences in several central aspects of a patient's quality of life, including intimacy, body image, human relationships, sexuality, and fertility. Despite their importance, incidence, and impact on psychosocial well-being, sexual health care (SHC) is a matter not frequently de...

Over the last decades, obesity has been increased in alarming rates not only in our country but also worldwide, tending to become one of the major health problems in the western world. Purpose: The purpose of the present study was to explore the relationship between dietary patterns and body mass index, as well as central obesity in young adult men...