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Introduction: Central sensitization (CS) was first defined in animal studies to be increased nociceptive responsiveness due to sensitization of neurons in the central nervous system, usually the result of prolonged nociceptive input or a disease state. Recently, the concept of CS has been adopted in clinical assessments of chronic pain, but its di...
Introduction: Evidence suggests that attention to pain is a product of both incoming sensory signals and cognitive evaluation of a stimulus. Intrinsic attention to pain (IAP) is a measure that captures an individual's natural tendency to attend to a painful stimulus and may be important in understanding why pain disrupts cognitive functioning in s...
Background & Aims Much is known about the impact of pain in terms of medical costs and missed work. Less is known about its associations when individuals are present for work. This study examines “presenteeism” by analysing the psychosocial costs of pain in the workplace, using the 2015 European Working Conditions Survey (EWCS). Methods We conduct...
To identify predictive biomarkers for pain sensitisation in an experimental study utilising thermal stimulation, brain imaging and cognitive behavioural therapy
1) To examine the processes that lead to pain becoming chronic and to determine whether early psychological intervention might reverse these processes using an experimental model of prolonged pain exposure; and 2) To establish a psychometrically convergent set of behavioural and neural markers of the mechanisms leading to pain chronification which can be translated into clinical use.