Gregory Reychler

Université Catholique de Louvain - UCLouvain | UCLouvain · Institute of Experimental and Clinical Research (IREC)

Introduction Nasal irrigation is regularly used in infants to relieve upper airway symptoms. However, because there is no consensus on good practice, nasal irrigation in infants is described and applied heterogeneously among clinicians and between clinical trials. Objective The aim of this study was to establish consensus regarding the use of nasa...

Only a few data associated to wearability of facemask during exercise are available in children. The aim of the study was to evaluate the effect of wearing a facemask on perceived exertion (primary aim), dyspnea, physical performance, and cardiorespiratory response during a submaximal exercise test in children aged between 8 and 12 years. This stud...

Background and objective: Evidence is shown for the benefits of physical activity, for patients with lung cancer, at different times through the course of the disease. Telerehabilitation can overcome some of barriers often met by patients to practice physical activity. The objective of this systematic review is to assess feasibility and safety of...

Background: Wearing a surgical mask in hospitalized patients has become recommended during care, including rehabilitation, to mitigate coronavirus disease 2019 (COVID-19) transmission. However, the mask may increase dyspnoea and raise concerns in promoting rehabilitation activities in post-acute COVID-19 patients. Objective: To evaluate the impa...

Background: Treating hypoxemia while meeting the soaring demands of oxygen can be a challenge during the COVID-19 pandemic. Objective: To determine the efficacy of the surgical facemask and the double-trunk mask on top of the low-flow oxygen nasal cannula on arterial partial pressure of oxygen (PaO2) in hypoxemic COVID-19 patients. Design: Ran...

Background: Adherence to treatment is critical when dealing with chronic diseases. One of the difficulties in maintain long-term adherence is the distance from home to rehabilitation center. Objective: To determine the influence of the distance from subjects’ residence to rehabilitation center on adherence of a 12-week pulmonary rehabilitation prog...

The number of people with obesity continues to increase. Bariatric surgery is the most effective treatment for severe obesity. However, this surgery also has disadvantages, such as an increased risk of excessive loss of fat-free mass, lean body mass, and muscle mass compared to other weight loss interventions. PubMed and Cochrane Library database i...

Dysphagia is common in patients with neuromuscular diseases (NMDs). Its management differs by country and clinical setting. The purpose of this study was to describe current practices in the management of dysphagia in NMDs across Europe. An online survey of sixteen questions was developed, including basic information on facilities, existence of a m...

Introduction La technologie Simeox produit de manière non invasive une succession de petites dépressions d’air dans l’arbre bronchique pendant la phase expiratoire. Ce faisant, la technologie Simeox a pour objectif de limiter ou retarder l’apparition du collapsus dynamique des bronches, ce qui devrait réduire l’hyperinflation statique chez les pati...

Introduction L’inconfort respiratoire à l’effort est le symptôme le plus commun chez les patients atteints de BPCO. L’utilisation du menthol a récemment démontré une diminution de la perception d’essoufflement à l’effort chez des sujets sains. Nous avons émis l’hypothèse que mâcher un chewing-gum à la menthe avant un effort pourrait diminuer la per...

Oxygenation through High Flow Delivery Systems (HFO) is described as capable of delivering accurate FiO2. Meanwhile, peak inspiratory flow V˙I ) of patients with acute hypoxemic respiratory failure can reach up to 120 L/min, largely exceeding HFO flow. Currently, very few data on the reliability of HFO devices at these high V˙I are available. We so...

Objective: To evaluate the effects and safety of exercise training, and to determine the most effective exercise intervention for people with Duchenne muscular dystrophy. Exercise training was compared with no training, placebo or alternative exercise training. Primary outcomes were functioning and health-related quality of life. Secondary outcome...

Introduction Le syndrome de la peau sensible a une origine neuropathique. C’est pourquoi il est fréquemment associé au syndrome du côlon irritable ou aux yeux sensibles. Nous avons recherché une éventuelle association avec la toux chronique, qui est fréquemment entretenue par des mécanismes neurogènes, quelle que soit la ou les causes initiales. M...

Background Only a few data associated to wearability of facemask during exercise are available in children. The aim of the study was to evaluate the effect of wearing a facemask on perceived exertion (primary aim), dyspnea, physical performance, and cardiorespiratory response during a submaximal exercise test in children aged between 8 and 12 years...

Background: The delivery of a high and consistent FIO2 is imperative to treat acute hypoxemia. The objective of this study was to analyze the effective inspired oxygen concentration delivered by different low-flow oxygen therapy systems challenged with different oxygen flows and respiratory patterns in an experimental lung model. Methods: An adult...

Rationale Several studies have evaluated the effect of nasal high flow (NHF) to enhance exercise performance and tolerance in patients with COPD, however results are disparate. Objective The aim of this systematic review and meta-analysis was to assess the effect of NHF as an adjuvant to exercise training on functional exercise capacity in patients...

Chewing menthol gum prior to exercise is a safe, easy-to-implement, low-cost, non-pharmacologic intervention that provides a reduction in dyspnoea in a third of patients and decreases the perception of discomfort during exercise in two-thirds of patients https://bit.ly/3FoFHp1.

Sensitive skin syndrome has a neuropathic origin, which is why it is frequently associated with irritable bowel syndrome. We have looked for a possible association with chronic cough, which is commonly maintained by neurogenic mechanisms, whatever the initial cause(s). A survey was carried out on a representative sample of the population over 15 ye...

The study aims to evaluate the feasibility and the safety of early mobilization in critically ill children under 2 years and its impact on comfort scores. This prospective, monocenter clinical trial was conducted in a tertiary care pediatric intensive care unit in Belgium. Twenty children were recruited to the study. Early mobilization was done bet...

Objectives This systematic review aimed to discuss the prevalence and the risk factors of the musculoskeletal pain in chronic obstructive pulmonary disease (COPD). Data source and study selection Four databases were analysed (Scopus, PubMed, Cochrane and EMBASE). We excluded systematic reviews, meta-analyses, conference abstracts and case reports....

Background Surgical (SM) or cloth facemasks (CM) has become mandatory in many public spaces during the COVID-19 pandemic. They may interfere with the participation in physical activities. Objective To evaluate how these masks influence dyspnoea (primary outcome), exercise performance and cardiorespiratory response during a 1-min sit-to-stand test...

Background: Field tests are useful to assess the functional exercise capacity. The 6 minute walking test (6MWT) is the most common field test even if alternatives are needed. The main aim of the study was to verify if the 3 minute step test (3MST) is a valid tool to measure the functional exercise capacity and can surrogate the 6MWT in healthy chil...

Physiotherapy techniques are regularly prescribed in the hypermobile type Ehlers–Danlos syndrome (hEDS) and they are appreciated by the patients. The objective of this systematic review was to investigate the effect of the different physiotherapy techniques related to the children and adult patients with hEDS. PubMed, SPORTDiscus, Cochrane Library,...

Background the perception of dyspnea is a subjective feeling typically self-assessed by the patient. However, the assessment by a caregiver is sometimes required. Objectives the primary aim was to compare patient self-assessment and caregiver assessment of dyspnea (interrater reliability) using the modified Borg and visual analogue scale (VAS) in...

Introduction/aims: Oropharyngeal dysphagia is common in patients with neuromuscular diseases (NMDs). Its early recognition is vital for proper management. We tested a large cohort of adult NMD patients for oropharyngeal dysphagia using the Sydney Swallow Questionnaire (SSQ). We also looked for possible differences in characteristics of oropharynge...

This study reports that the TCD4 cell levels are not related to physical adaptation in People Living with HIV

Oxygen gas flowmeters (OGF) are used to regulate the oxygen flow in acute and chronic care. In hospitals, Thorpe tubes (TT) are the classical systems most used for delivering oxygen. In recent years, the oxygen flow restrictor (OFR) has appeared. These devices use a series of calibrated openings in a disk that can be adjusted to deliver different f...

Background COVID-19 pandemic resulted in an unprecedented number of hospitalizations in general wards and intensive care units (ICU). Severe and critical COVID-19 patients suffer from extensive pneumonia; therefore, long-term respiratory sequelae may be expected. Research question We conducted a cohort study to determine respiratory sequelae in pa...

Résumé Les maladies respiratoires chroniques s’accompagnent souvent de nombreuses comorbidités qui contribuent à la diminution de la capacité à l’exercice et d’une altération des capacités fonctionnelles et musculaires qui affectent la qualité de vie des personnes qui en sont atteintes et qui peuvent toutes être améliorées par la réadaptation respi...

Background The impact of the COVID-19 pandemic on functional exercise capacity seemed quickly clinically evident. The objective of this study was to assess the functional exercise capacity of patients with severe COVID-19 and to evaluate the effect of a telerehabilitation program in the specific context of the COVID-19 pandemic. Method Patients ho...

Background Substantial postoperative complications occur after tumor resection for esophagogastric cancers. Physical prehabilitation programs aim to prepare patients for surgery by improving their functional status with the aim of reducing postoperative complications. This systematic review aims to summarize the effects of physical prehabilitation...

Background: Quadriceps muscle weakness and reduced exercise tolerance are prevalent in patients with cystic fibrosis (CF) and associated with a worse prognosis. The one-minute sit-to-stand test (1STST) has been proposed to evaluate exercise capacity and assess quadriceps strength. The aim of the study was to correlate the 1STST and the maximal isom...

Exercise training has shown beneficial effects in the management of radiotherapy-related side effects in prostate cancer (PCa) patients undergoing radiation therapy (RT). However, the optimal modality of the exercise programs have not been yet determined. The aim of this randomized controlled trial was to investigate the effects of high-intensity i...

Riassunto La bronchiolite acuta del lattante (BAL) è un’infezione virale del tratto respiratorio inferiore. Andando da una forma lieve, compatibile con una gestione ambulatoriale, a una forma più grave, che richiede il ricovero in ospedale, la sua gravità può variare da un bambino all’altro. Tuttavia, la gestione in fisioterapia respiratoria (FR) a...

Background Functional exercise capacity assessment is recommended in children with cystic fibrosis (CF). The six-minute walk test (6MWT) is a valid evaluation of exercise capacity but can be technically complex. Inversely, the sit-to-stand test (STST) is a simple method to evaluate exercise capacity, and is validated in healthy children and adults...

Background: Oxygen uptake (V̇O2) kinetics have been shown to be slowed in adolescents with cystic fibrosis (CF) during heavy-intensity cycling and maximal exercise testing. Objectives: This study investigated V̇O2 kinetics in adolescents with CF compared to control adolescents (CON) during a treadmill-walking exercise. Methods: Eight adolescents wi...

Introduction Les patients atteints de pathologies neuromusculaires ou neurologiques ont régulièrement des déformations rachidiennes de type scoliotique. Les spécificités de la scoliose (atteinte musculaire, degré de la courbure, niveau et la rotation de la colonne vertébrale) et les complications associées (positionnement, corset, orthèse et autres...

Background: The purposes of this study were to verify the correlation between chest expansion and lung function within a larger sample of subjects composed of both healthy subjects and subjects affected by pulmonary disease, and to verify the influence of age, body mass index, and gender on chest expansion. Methods: Adults were recruited prospec...

Résumé La nébulisation est un mode d’administration des traitements inhalés dont la prescription et la mise en place restent délicates. Ces bonnes pratiques, réalisées par le GAT (groupe aérosolthérapie de la SPLF), étaient nécessaires, les dernières datant de 2007. Plus encore qu’une actualisation des données sur le sujet, ces recommandations d’ex...

Objective To investigate the effects of rehabilitation methods on leg muscle function and functional performance in cystic fibrosis. Data sources A literature search was conducted in PubMed (MEDLINE), Scopus and the Cochrane Library from inception to October 12, 2020. A secondary hand search through reference lists from identified articles was con...

Riassunto L’aerosolterapia è una modalità terapeutica comunemente utilizzata nel contesto dei disturbi respiratori. Globalmente, si può dire che solo una piccola parte del farmaco iniziale raggiungerà le vie aeree del soggetto. Esistono sul mercato diversi tipi di dispositivi che permettono di erogare un aerosol, che vanno dagli aerosol-dosatori pr...

Background: Human Immunodeficiency Virus (HIV) disproportionately affects populations depending on countries. Sub-Saharan Africa is the most affected region. Antiretroviral therapy is a key element for increasing life expectancy of infected people with a better quality of life (QoL). Regardless of this treatment, the QoL of these populations is oft...

Tele-rehabilitation provides better access to healthcare services and optimizes exercise adherence. However, its feasibility and effectiveness are unknown in the preoperative period in esophagogastric cancer patients. We aimed to assess the feasibility and the preliminary effects of a “tele-prehabilitation” program in esophagogastric cancer patient...

Despite its beneficial effects, radiotherapy still results in a range of side effects that negatively impact quality of life of patients. Exercise has been shown to counteract the side effects induced by cancer treatment. This narrative review aims to provide an up-to-date review of the effects of an exercise intervention in cancer patients during...

Accurate testing of muscle function is essential in individuals with cystic fibrosis (CF). A literature search was conducted in MEDLINE, CENTRAL, CINAHL, PEDro, ScienceDirect and Web of Science according to PRISMA and COSMIN guidelines from inception to September 2019 to investigate the clinimetric properties of muscle tests in individuals with CF....

Resumen La aerosolterapia es una modalidad terapéutica que se utiliza corrientemente en el marco de las enfermedades respiratorias. De forma global, puede decirse que solo una pequeña proporción del medicamento inicial alcanzará las vías respiratorias del paciente. Existen en el mercado distintos tipos de dispositivos que permiten administrar un ae...

Background: Clinical tools for assessment of the skeletal muscle strength are scarce and have rarely been validated in children. The aims of this study were to verify the construct validity of the one-minute sit-to-stand test (1-MSTST) to evaluate the quadriceps strength in healthy children between 12 and 18 years old and to correlate these outcome...

Abstract: Noninvasive ventilation (NIV) during exercise has been suggested to sustain higher training intensity but the type of NIV interface, patient-ventilator asynchronies (PVA) or technological limitation of the ventilator may interfere with exercise. We assessed whether these parameters a�ect endurance exercise capacity in severe COPD patients...

In this randomised, crossover trial, 22 patients with severe chronic obstructive pulmonary disease climbed six flights of stairs (108 steps) twice, under two test conditions: (1) energy conservation technique (ECT): participants were asked to rest for at least 5 seconds every three steps and (2) control condition: participants climbed the stairs at...

In patients with hypoxemic respiratory failure, the association of the Double Trunk Mask with low flow nasal cannula increases the PaO2 significantly. The PaCO2 increases statistically, but the size effect is small and not clinically significant.

La bronchiolite aiguë du nourrisson (BAN) est une infection virale des voies respiratoires inférieures. Allant d'une forme bénigne compatible avec une prise en charge ambulatoire à une forme plus grave requérant l'hospitalisation, sa sévérité peut varier d'un enfant à l'autre. Pourtant, la prise en charge en kinésithérapie respiratoire (KR) associé...

Introduction L’évaluation des capacités à l’exercice est recommandée avec la réalisation d’une épreuve d’effort incrémentale ou d’un test de marche de 6 minutes (TDM6) chez les enfants de plus 10 ans atteints de mucoviscidose. Ces deux évaluations peuvent être limitées par des contraintes techniques et une incertitude existe pour les enfants plus j...

Background: Patients with neuromuscular disorders (NMDs) are likely to develop respiratory failure which requires noninvasive ventilation (NIV). Ventilation via a mouthpiece (MPV) is an option to offer daytime NIV. Objectives: To determine the preferred equipment for MPV by patients with NMDs. Methods: Two MPV equipment sets were compared in 2...

Background: Air-flow oscillations generated by exhaling through oscillatory positive expiratory pressure (OPEP) devices favor airway clearance. Variations in mechanical properties between different devices may influence therapeutic efficacy. The objective of this study was to assess mechanical properties in vitro and to compare the performance of...

Objective: To evaluate the impact of combining nebulised hyaluronic acid plus hypertonic saline (HA+HS) with oscillatory positive expiratory pressure (oscillatory-PEP) on sputum expectoration and related symptoms in adults with cystic fibrosis (CF). Design: Randomised crossover trial. Setting: Seven centres. Participants: Twenty-two outpatie...

We developed a training protocol based on Intrapulmonary Percussive Ventilation in order to prolong breath-hold while nearly suppressing the thorax motion. This protocol allowed ten subjects to achieve a 20-minutes-breath-hold, while reducing the residual surface motion to 1 mm around its mean position for more than 95% of the breath-hold duration.