Grace W K Tang

Grace W K Tang
The University of Hong Kong | HKU · Department of Obstetrics and Gynaecology

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95
Publications
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6,201
Citations
Citations since 2017
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1384 Citations
2017201820192020202120222023050100150200250300
2017201820192020202120222023050100150200250300
2017201820192020202120222023050100150200250300
2017201820192020202120222023050100150200250300

Publications

Publications (95)
Article
The aim of this study is to investigate the effectiveness and safety of a Chinese herbal formula, Er-Xian decoction (EXD), in the treatment of menopausal symptoms among Hong Kong perimenopausal women. A randomized, double-blind, controlled trial was conducted for 12 weeks among 108 Hong Kong perimenopausal women who reported Menopause Rating Scale...
Article
The primary objective of this report is to describe the detection of adenocarcinoma in situ (AIS) and associated human papillomavirus (HPV) type distribution that was observed in the context of two phase 3 clinical trials of a quadrivalent HPV6/11/16/18 vaccine. In this intention-to-treat analysis, we include all women who had at least one follow-u...
Article
Full-text available
To evaluate the prophylactic efficacy of the human papillomavirus (HPV) quadrivalent vaccine in preventing low grade cervical, vulvar, and vaginal intraepithelial neoplasias and anogenital warts (condyloma acuminata). Data from two international, double blind, placebo controlled, randomised efficacy trials of quadrivalent HPV vaccine (protocol 013...
Article
Prenatal diagnosis of Thanatophoric Dwarfism by ultrasonography was made at 36 weeks in a pregnancy complicated by polyhydramnios. The diagnosis was based on the evidence of extremely short and deformed limbs, a narrow thorax relative to the abdomen and a degree of hydrocephalus. Progressive hydrocephalus as evidenced by repeated ultrasonography in...
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Full-text available
The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat...
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Quadrivalent human papillomavirus (HPV) vaccine has been shown to provide protection from HPV 6/11/16/18-related cervical, vaginal, and vulvar disease through 3 years. We provide an update on the efficacy of the quadrivalent HPV vaccine against high-grade cervical, vaginal, and vulvar lesions based on end-of-study data from three clinical trials. A...
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Full-text available
In the quadrivalent (types 6/11/16/18) HPV vaccine (GARDASIL/SILGARD) clinical program, 73% of women aged 16-26 were naïve to all vaccine HPV types. In these women, prophylactic administration of the vaccine was highly effective in preventing HPV 6/11/16/18-related cervical disease. Of the remaining women, 15% of had evidence of past infection with...
Article
Human sexuality is considered in the present day as an integral part of a medical curriculum. The modifications made in the human sexuality course and the difficulties encountered in teaching Chinese medical students during the past 5 years are described and discussed.
Article
A retrospective study of the changes in sexual function of 103 Chinese patients after treatment for carcinoma of cervix was done. Ten patients were irradiated, 40 patients were treated by surgery and 53 patients received both surgery and irradiation. Changes in sexual function were noted in all 3 groups. Patients who had undergone major operation w...
Article
Men with the spermatological symptom of polyzoospermia (greater than 250 X 10(6) sperm/ml) have been reported to seldom impregnate their wives. It was the aim of this study to investigate the spermatozoal fertilizing capacity in polyzoospermia by the human sperm and zona-free hamster ova penetration bioassay. General semen characteristics and in vi...
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Full-text available
We evaluated the impact of a quadrivalent human papillomavirus (HPV) vaccine on infection and cervical disease related to 10 nonvaccine HPV types (31, 33, 35, 39, 45, 51, 52, 56, 58, and 59) associated with >20% of cervical cancers. The population evaluated included HPV-naive women and women with preexisting HPV infection and/or HPV-related disease...
Article
Full-text available
Human papillomavirus (HPV)-6/11/16/18 vaccine reduces the risk of HPV-6/11/16/18-related cervical intraepithelial neoplasia (CIN) 1-3 or adenocarcinoma in situ (AIS). Here, its impact on CIN1-3/AIS associated with nonvaccine oncogenic HPV types was evaluated. We enrolled 17,622 women aged 16-26 years. All underwent cervicovaginal sampling and Pap t...
Article
Seminal plasma beta-human chorionic gonadotropin (beta-HCG) levels were determined in 254 semen samples collected from fertile and suspected subfertile men, and their relationships with seminal characteristics and spermatozoal fertilizing capacity were evaluated. Radioimmunoassayable beta-HCG, as defined by greater than 5 mIU/ml concentration, was...
Article
The efficacy of the quadrivalent Human Papillomavirus (HPV) vaccine is thought to be mediated by humoral immunity. We evaluated the correlation between quadrivalent HPV vaccine-induced serum anti-HPV responses and efficacy. 17,622 women were vaccinated at day 1, and months 2 and 6. At day 1 and at 6-12 months intervals for up to 48 months, subjects...
Article
To evaluate results of three phase 3 clinical trials of quadrivalent HPV 6/11/16/18 vaccination of young Asia-Pacific women. A total of 814 women from the Asia-Pacific region (aged 16 to 26 years) received vaccine or placebo in 1 of 3 protocols. Descriptive analyses focused on the efficacy, safety, and immunogenicity of the vaccine and the natural...
Article
Independent risk factors for osteoporotic fracture were identified for a Southern Chinese postmenopausal population. Clinical risk factor assessment with or without BMD measurement was shown to be an effective predictor of 10-yr risk of osteoporotic fracture and provides a more accessible tool for patient evaluation. Asian-specific data on risk fac...
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Full-text available
The incorporation of multiple antigens into a single human papillomavirus (HPV) vaccine may induce immune interference. To evaluate whether interference occurs when HPV type 16 (HPV16) virus-like particles are combined in a multivalent vaccine, we conducted a study to evaluate anti-HPV16 responses among subjects receiving three-dose regimens of eit...
Article
Vulval and vaginal cancers among younger women are often related to infection with human papillomavirus (HPV). These cancers are preceded by high-grade vulval intraepithelial neoplasia (VIN2-3) and vaginal intraepithelial neoplasia (VaIN2-3). Our aim was to do a combined analysis of three randomised clinical trials to assess the effect of a prophyl...
Article
Full-text available
A phase 3 trial was conducted to evaluate the efficacy of a prophylactic quadrivalent vaccine in preventing anogenital diseases associated with human papillomavirus (HPV) types 6, 11, 16, and 18. In this randomized, placebo-controlled, double-blind trial involving 5455 women between the ages of 16 and 24 years, we assigned 2723 women to receive vac...
Article
This study was conducted to determine whether a particular Chinese medicinal preparation is effective in alleviating menopausal symptoms. Chinese women with menopausal symptoms were recruited to receive treatment for 3 months followed by 3 months without treatment. The severity of menopausal symptoms and serum follicle-stimulating hormone (FSH), lu...
Article
To compare the biochemical markers of bone turnover in hypoestrogenic women who had been on the standard dosage of Premarin 0.625 mg to that of the age-matched women who were menstruating spontaneously. Chinese women between 25 and 40 years of age with a diagnosis of hypoestrogenism who had been on Premarin 0.625 mg daily for more than 1 year were...
Article
To determine the impact of Women Health Initiative (WHI) trial on the use of hormone replacement therapy (HRT) in the Hong Kong public health sector. The central prescription database of the Hospital Authority was used to describe the half-yearly trend in the use of HRT between July 2000 and December 2003. The data of hysterectomy was retrieved fro...
Article
To assess the 1-year continuation rate of HRT prescribed in Hong Kong public health sector and to identify factors affecting this continuation rate. All women who received at least one dispensed prescription of estrogens between January 1998 and December 2000 from 36 specialist outpatient clinics of the Hospital Authority were selected, and observe...
Article
Full-text available
Medical practitioners are certified as competent when they graduate from medical schools. They are certified as competent specialists after they have completed the various specialist training programmes. To maintain specialist status, the commonest requirement is mandatory continuing professional development (CPD), and in some places, continuing me...
Article
Full-text available
Severe acute respiratory syndrome (SARS) epidemics have affected populations in many countries, including Hong Kong. This disease is infectious, especially in hospital settings. Health care workers have expressed great concern, including those working in obstetrics wards, defined as high-risk areas. Four weeks after implementation of universal prec...
Article
Background: Severe acute respiratory syndrome (SARS) epidemics have affected populations in many countries, including Hong Kong. This disease is infectious, especially in hospital settings. Health care workers have expressed great concern, including those working in obstetrics wards, defined as high-risk areas. Method: Four weeks after implementati...
Article
A bacterium was isolated from the pus of a patient with pelvic actinomycosis. The cells were strictly anaerobic, straight, non-sporulating, Gram-positive rods. It grows on sheep blood agar as non-haemolytic, pinpoint colonies after 24 hours of incubation at 37 degrees C in anaerobic environment. It is non-motile and does not produce catalase. 16S r...
Article
The Faculty of Medicine of the University of Hong Kong launched its new medical curriculum in 1997. It was an integrated and system-based curriculum, with problem-based learning (PBL) being one of its new pedagogy. This paper describes the quality assurance of the introduction of PBL. Regular PBL tutor training and case-writing workshops were condu...
Article
Objective: The objective was to describe the change in psychosocial state over time and to identify risk factors for maladjustment in gynecologic cancer survivors. Awareness of these issues is important for planning supportive care services for cancer patients. Methods: A longitudinal prospective study of patients with newly diagnosed gynecologi...
Article
Bone mineral density (BMD) has been shown to be different in different ethnic groups. When lifestyle and diet evolve, there is a possibility of a change in the normal reference BMD values within an ethnic group over a period of time. As the osteoporotic risk uses the T-score as the bench mark, it is pertinent to evaluate whether such changes do occ...
Article
Cross-sectional studies on the effects of depot-medroxyprogesterone acetate (DMPA) on bone mineral density (BMD) have been controversial. The present longitudinal cohort study on 59 Chinese women over a period of 3 years has shown that their annual rate of bone loss at 3 sites (0.44% in lumbar spine, 0.40% in neck of femur, 1.05% in Ward's triangle...
Article
Quantitative ultrasound (QUS) is emerging as a simple, inexpensive and noninvasive method for assessing bone quality and assessing fracture risk. We assessed the usefulness of a contact calcaneal ultrasonometer by studying normal premenopausal women (group I, n = 53), normal postmenopausal women (group II, n = 198), and osteoporotic women without (...
Article
In a randomized, double-blind study, the antiemetic efficacy of a single bolus of tropisetron 5 mg (group T, 37 patients), ondansetron 4 mg (group O, 39 patients) or saline (group C, 45 patients) given at induction was compared in a homogeneous group of 121 patients undergoing gynaecological laparotomy and receiving postoperative patient-controlled...
Article
Quantitative ultrasound (QUS) assessment at the calcaneus has been found to be a safe and reliable method for evaluating skeletal status. The present study aimed at evaluating the precision of the Sahara bone ultrasound densitometer and to determine the normative QUS data in healthy southern Chinese women. Broadband ultrasound attenuation (BUA), sp...
Article
The association between long-term use of depot-medroxyprogesterone acetate (DMPA) and bone mineral density (BMD) has been controversial, as seen in three case-control studies in New Zealand, Thailand, and the United Kingdom. In the present case-controlled study of BMD, a group of 67 Chinese women who had used DMPA from 5-15 years was compared with...
Article
Full-text available
The patterns of plasma melatonin, gonadotropins, sex steroids and prolactin were studied in anovulatory infertile females undergoing ovulation induction with hMG/hCG. Melatonin levels were found to fluctuate during the menstrual cycle of these subjects with a nadir at mid-cycle and peak occurring at the early follicular/late luteal phases of the cy...
Article
The evolution of myomectomy 'scars' has not been reported. This prospective study was carried out to determine the evolution of the myomectomy 'scars' following conventional open myomectomy. Ten patients admitted for myomectomy were recruited. The sizes of the leiomyomata were determined with ultrasonography. Serial sonographic examinations were pe...
Article
Full-text available
The following guidelines provide a basis for the management of osteoporosis for the practising physician in Hong Kong. The guidelines have been complied by a working group that represents the specialties concerned with osteoporosis and summarise the current management of osteoporosis based on available published evidence and relevant local experien...
Article
Trauma to abdominal wall blood vessels occurs following 0.2–2% of laparoscopic operations. This prospective observational study assessed the possible role of sonographic localization of abdominal blood vessels prior to laparoscopic surgery in Chinese women and compared the findings reported in a Western group. The inferior epigastric and superficia...
Article
The pretreatment mixed cross-sectional and longitudinal height measurements of 203 patients with Turner's syndrome (TS) were analysed. Only one observation was included per year per child and a total of 858 observations formed the basis of the growth study. The mean and SD values were fitted separately by a second-degree polynomial function, giving...
Article
This report describes the development of a haematoma in the mesentery following laparoscopic ovarian cystectomy. A possible differential diagnosis and possible strategies to prevent this complication are discussed.
Article
To study the effect of the timing of laparoscopic cholecystectomy following acute gallstone pancreatitis. University-based county teaching hospital. Retrospective case series. One hundred forty-two patients with gallstone pancreatitis treated by laparoscopic cholecystectomy between April 1991 and September 1993. There were 16 men and 126 women, wit...
Article
Ten Chinese women who had menorrhagia without organic cause and suffered from anaemia were treated with levonorgestrel intrauterine device for a total of 129 woman-months. There was a 54%, 87% and 95% reduction in menstrual blood loss at the first, third and sixth month of treatment when compared with the pretreatment cycle. These percentages of re...
Article
Chinese factory workers (427) mainly of Fujian origin were found to have few climacteric symptoms. Of these, 65% and 50% reported having no circulatory and nervosity symptoms, respectively. Only 18% of women experienced hot flushes. The climacteric symptoms were more pronounced at the perimenopausal period (P < 0.001) when these women experienced m...
Article
Psychosocial support and adjustment to cancer in 115 Chinese patients with gynecological malignancies were studied by interviews using semi-structured and structured questionnaires before commencement of treatment. Ninety per cent of patients had emotional support with 72% coming from family members, while 77% of the patients said that they were cl...
Article
Of 144 consecutive women who requested early induced abortion, 99 (68.7%) and 45 (31.3%) women chose RU486 combined with ONO 802 (medical method) and suction evacuation (surgical method), respectively. Logistic regression analysis of covariates showed that age and marital status were significantly correlated with the acceptability and hence the cho...
Article
The objective of this study is to identify prognostic factors affecting mortality in surgical patients with culture-proved fungemia and to examine how amphotericin B affects mortality after controlling for these factors. The study is based on a retrospective logistic regression analysis of general surgical patients with blood cultures positive for...
Article
Seventy-five patients with a total of 306 human menopausal gonadotropin treatment cycles over the period 1984-1989 were analysed retrospectively to evaluate the value of transabdominal pelvic ultrasonography in prevention of complications arising from ovulation induction with human menopausal gonadotropins. There were 60 pregnancies giving a pregna...
Article
We have previously demonstrated that in patients with oestrogen deficiency, there was a significant reduction in the ratio of CD4+ to CD8+ lymphocytes. To test our hypothesis that oestrogen deficiency was the cause of the changes in lymphocyte subsets, we have studied the lymphocyte subsets and serum immunoglobulin levels in 35 patients with idiopa...
Article
RU486 and ONO 802 in combination have been shown to be effective in early termination of pregnancy. Anecdotal information suggests that Chinese women have been using herbs to induce abortion, believing that such medication and means of abortion is less harmful to the body than surgery. Hence, a medical means of abortion using RU486 and ONO 802 may...
Article
We have previously shown that in patients with idiopathic premature ovarian failure there were significant changes in lymphocyte subsets. To test our hypothesis that these changes were due to oestrogen deficiency we studied lymphocyte subsets in patients with oestrogen deficiency due to other causes. Blood was taken for serum oestradiol, lymphocyte...
Article
Gonadal dysgenesis is the commonest cause of primary amenorrhea. Women with such a disease syndrome feel physically healthy but they lack the two bodily functions which are exclusively feminine: menstruation and child-bearing. The present study of 86 Chinese women with gonadal dysgenesis showed that their congenital abnormalities did not interfere...
Article
Fifteen years' experience in a Menstrual Disorder Clinic revealed that gonadal dysgenesis was the commonest cause of primary amenorrhoea. Investigations using Barr Body study and laparoscopic examination were unsatisfactory and inaccurate. The invasive nature of laparoscopy was the likely principal cause for the high default rate in the early years...
Article
Fifteen years' experience in a Menstrual Disorder Clinic revealed that gonadal dysgenesis was the commonest cause of primary amenorrhoea. Investigations using Barr Body study and laparoscopic examination were unsatisfactory and inaccurate. The invasive nature of laparoscopy was the likely principal cause for the high default rate in the early years...
Article
Forty Chinese women undergoing gynaecological operations for benign conditions of the genital tract were studied using a number of questions to define their attitudes and responses to surgery. The possibility of developing a ‘Predictive Score’ was explored with a provisional measure related significantly with psychological outcome at 6 weeks postop...
Article
Sterilization has become a popular means of birth control and many methods have been developed to meet the needs of different groups of women. In a pilot study, non-surgical sterilization using phenol-mucilage was found to be extremely acceptable to a group of Chinese women despite its failure rate. The method is simple, safe and inexpensive. It is...
Article
EDITORIAL COMMENT: These authors previously reported that a first morning urinary oestrogen to creatinine ratio correlates well with 24-hour urinary oestrogen excretion (13). This paper reports the successful application of this assay in monitoring the ovarian response to gonadotrophin therapy. Summary: Efficient gonadotrophin therapy requires both...
Article
Tests for a range of autoantibodies, and counts of lymphocytes, B cells, T cells, and T cell subsets were performed in 45 Chinese patients with premature ovarian failure and 45 age-matched normal control subjects. Eight patients (18%) were positive for at least one autoantibody. Only one patient was positive for antiovarian antibody. Patients with...
Article
Serum Schwangerschafts-protein 1 (SP1) and beta subunit of human chorionic gonadotropin (beta-hCG) were measured by enzyme immunoassay and radioimmunoassay, respectively, in the follicular phase and luteal phase of 50 human menopausal gonadotropin treatment cycles. SP1 could be detected in 63% of blood samples taken in the follicular phase up to th...
Article
Reports on sexual functioning following treatment for carcinoma of the cervix are many and the results are conflicting. The modalities of treatment have been considered to play a significant role. A study of 99 patients showed that 20 (20.2%) of them became sexually inactive after treatment. For those who remained sexually active, the degree of cha...
Article
Daily serum immunoreactive beta-endorphin (IR-beta-EP) levels, in conjunction with luteinizing hormone, follicle-stimulating hormone, 17 beta-oestradiol, progesterone, and prolactin, were measured during the ovulatory cycle in five healthy Chinese women. Standardization of raw data by conversion to the statistical "Z scores" and composite plot of t...
Article
Plasma concentrations of immunoreactive melatonin, estradiol, progesterone, follicle stimulating hormone (FSH), and β-human chorionic gonadotropin (βhCG) were studied between 1000 and 1230 h in 105 Chinese females during six periods of normal pregnancy and 1–5 min after normal delivery. We have also examined the midday levels of immunoreactive mela...
Article
Seven hundred and twenty-five male Hong Kong Chinese patients were examined during the period of 1980–1984 for the presence of circulating sperm antibodies by the Kibrick sperm macroagglutination test and the Isojima sperm immobilization test as part of the couple's infertility investigation. The overall incidences for the sperm agglutinating and t...
Article
One thousand five hundred and twenty-six records of deliveries with vacuum extractor in 1982 and 1983 in the Hong Kong University Department of Obstetrics and Gynaecology were reviewed. Vacuum extractor was found to be easy and safe to use even by inexperienced house-staff. Vacuum extractor was especially useful in the delivery of malpositioned fet...
Article
The pattern of change in the levels of prolactin (PRL) in cervical mucus was studied in 19 normal ovulatory women. The concentration of PRL in cervical mucus was generally higher than that in plasma except at midcycle, when a reverse relationship was observed. The concentration of PRL in mucus obtained at midcycle was lower than mucus obtained duri...
Article
Gestational trophoblastic disease has several special aspects as compared with others tumors of the female genital tract. It occurs in young women who want to start a family and expect to have a normal pregnancy. It can be very effectively treated with chemotherapeutic agents, and the subsequent reproductive potential of these young women is not af...
Article
The functional integrity of sperm membranes of 270 semen samples collected from fertile men and the male partners in couples with infertile marriages was assessed by the hypoosmotic swelling test and the results correlated with routine semen analysis and the human sperm zona-free hamster ovum penetration assay. Semen samples with abnormal semen par...
Article
The functional integrity of sperm membranes of 270 semen samples collected from fertile men and the male partners in couples with infertile marriages was assessed by the hypoosmotic swelling test and the results correlated with routine semen analysis and the human sperm zona-free hamster ovum penetration assay. Semen samples with abnormal semen par...
Article
The recovery from emergency hysterectomy of 18 Chinese patients is described. During the recovery period, patients experienced fear, depression, anger, doubt, selfreproach, and multiple somatic complaints without physical origins. Sexual activity was reduced. The recovery course was particularly difficult for those patients who were nonsymptomatic...
Article
A total of 410 semen samples from the male partners of infertile Hong Kong Chinese couples were examined during the period of January-October, 1984. The incidence of teratozoospermia was 12.7%, significantly higher than the value of 5.7% observed with a group of 35 normospermic control semen samples collected from the fertile donors. The mean sperm...
Article
As a preliminary study to analyze the relationship of obesity to menstrual disorders in Hong Kong Chinese women, the incidence of obesity in 219 patients with menstrual disorders attending the University of Hong Kong Department of Obstetrics and Gynaecology in two years' period (1981-1982) were reported. The incidence of obesity was 33.7% in 92 pat...
Article
Total 24-hour urinary oestrogen has been used extensively and proven to be reliable in monitoring gonadotrophin therapy for induction of ovulation. However, the method is time consuming for the patient and incomplete collection, as expected, is not uncommon, hence interfering with the treatment result. Oestrone-3-glucuronide in first morning urine...
Article
Thirty eight patients were treated in 135 treatment cycles with human menopausal gonadotrophin for induction of ovulation in Hong Kong University Gynaecological Unit since 1975. In 1975 to 1980, patients were monitored by vaginal cytology and cervical mucus everyday and plasma oestradiol on alternate days. The pregnancy rate was 52%. The multiple p...
Article
Ho PC, Tang GWK and Ma HK (Department of Obstetrics and Gynaecology, University of Hong Kong, Hong Kong). A critical evaluation of subfertility investigations. The investigations done for the infertile couple attending the Subfertility Clinic of the Hong Kong University Gynaecological Unit from 1975 to 1979 were reviewed. The Rubin's tubal insuffla...
Article
Seminal plasma prolactin (PRL) levels were determined in 224 semen samples collected from fertile and suspected infertile men, and their relationships with spermatozoal characteristics and fertilizing capacity in vitro were evaluated. PRL concentrations were similar in normospermic and oligospermic samples, but were significantly lower in azoosperm...
Article
The effect of exogenous prolactin (PRL) on the fertilizing capacity of human spermatozoa in vitro was evaluated by the zona-free hamster ova penetration assay. Bovine and ovine PRL, in both physiological and pharmacological concentrations, failed to increase the penetration after 5 hr of incubation in vitro. The percent motility of spermatozoa was...
Article
In 20 anovulatory patients who were normoprolactinaemic, 12 developed transient hyperprolactinaemia when they were treated with human menopausal gonadotropin (hMG) for induction of ovulation. The hyperprolactinaemia was probably due to the increased oestrogen production effect on some susceptible patients. The pregnancy rate was found to be lower i...
Article
Cancer is a disease associated with suffering and death. Cancer patients have special needs and related emotions which require special care. Much has been written on the psychosocial needs of Caucasian cancer patients and on what their physicians should do. A preliminary descriptive study was made on 21 Chinese women suffering from carcinoma of the...
Article
The potential functions of testosterone and 5 alpha-dihydrotestosterone, the androgens normally present in human seminal plasma, on human spermatozoal physiology were evaluated by studying the effects of these two steroid hormones on the in vitro fertilizing capacity of human spermatozoa. Spermatozoa collected from presumably fertile men were washe...
Article
The effect of a prostaglandin E1 analogue on the cervix prior to termination of first trimester pregnancy was studied in a double-blind placebo-controlled trial with 70 primigravid and 125 multigravid patients in the Hong Kong University Gynaecological Unit. One mg of 16, 16-dimethyl-trans-delta 2-prostaglandin E1 methyl ester (ONO 802) in the form...
Article
The findings of a retrospective study of 638 couples attending an infertility clinic in Hong Kong from 1975-79 are presented. Of these 72% had primary and 28% secondary infertility. Causes of infertility were: 1) ovulation disorders, 42.2%; 2) tubal factor, 16%; 3) unknown, 13.2%; 4) multiple factors, 11.1%; and 5) male factors, 9.7%. The only sign...
Article
Vacuum aspiration is the most common method of termination of pregnancy in the first trimester. Mechanical dilatation of the cervix can lead to cervical laceration and uterine perforation. There is also concern about the effect of cervical injury on subsequent reproductive performance1, 2. Therefore various types of natural prostaglandins and prost...
Article
Using radioimmunoassay for human chorionic gonadotrophin beta-subunit, 39 treatment cycles of clomiphene citrate therapy were studied prospectively for incidence of subclinical abortions. Eight treatment cycles resulted in clinically recognizable pregnancies and three other treatment cycles ended up with subclinical abortions. The plasma progestero...
Article
Abortion in single girls in an increasing problem in Hong Kong. This paper is an attempt to look at the psychosocial factors in sexual behavior in a selected sample of girls. Of 100 girls requesting an abortion, 70% were educated to Form III level (grade 10 U.S. equivalent) and these did not come from broken or disturbed homes. The adequacy of thei...

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