Grace Marion Power

Grace Marion Power
University of Bristol | UB · MRC Integrative Epidemiology Unit

Doctor of Philosophy

About

18
Publications
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48
Citations

Publications

Publications (18)
Article
Full-text available
Background Arboviruses transmitted by day-biting Aedes mosquitoes are a major public health concern. With the challenges inherent in arbovirus vaccine and therapeutics development, vector control and bite prevention strategies are among the limited options available for immediate intervention. Bite prevention through personal protective technologie...
Article
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Increased rates of Zika virus have been identified in economically deprived areas in Brazil at the population level; yet, the implications of the interaction between socioeconomic position and prenatal Zika virus exposure on adverse neurodevelopmental outcomes remains insufficiently evaluated at the individual level. Using data collected between Se...
Preprint
Full-text available
Background: The rising prevalence of childhood obesity has been postulated as an explanation for the increasing rate of individuals diagnosed with type 1 diabetes (T1D). However, robust causal evidence supporting this claim has been extremely challenging to uncover, particularly given the typical early onset of T1D. Methods: In this study, we used...
Article
Full-text available
Background Obesity is associated with long‐term health consequences including cardiovascular disease. Separating the independent effects of childhood and adulthood obesity on cardiovascular disease risk is challenging as children with obesity typically remain overweight throughout the lifecourse. Methods and Results This study used 2‐sample univar...
Article
Full-text available
Background: Vitamin D supplements are widely prescribed to help reduce disease risk. However, this strategy is based on findings using conventional epidemiological methods which are prone to confounding and reverse causation. Methods: In this short report, we leveraged genetic variants which differentially influence body size during childhood an...
Article
Full-text available
Mendelian randomization (MR) is an increasingly popular component of an epidemiologist's toolkit, used to provide evidence of a causal effect of one trait (an exposure, e.g. BMI) on an outcome trait or disease (e.g. osteoarthritis). Identifying these effects is important for understanding disease aetiology and potentially identifying targets for th...
Preprint
Background Vitamin D supplements are widely prescribed to help reduce disease risk. However, this strategy is based on findings using conventional epidemiological methods which are prone to confounding and reverse causation. Methods In this short report, we leveraged genetic variants which differentially influence body size during childhood and ad...
Article
Full-text available
The rising prevalence of childhood obesity has been postulated as an explanation for the increasing rate of individuals diagnosed with type 1 diabetes (T1D). In this study, we use Mendelian randomization (MR) to provide evidence that childhood body size has an effect on T1D risk (OR = 2.05 per change in body size category, 95% CI = 1.20 to 3.50, P...
Article
Full-text available
Introduction Arthropod-borne viruses (arboviruses) are of notable public health importance worldwide, owing to their potential to cause explosive outbreaks and induce debilitating and potentially life-threatening disease manifestations. This systematic review and meta-analysis aims to assess the relationship between markers of socioeconomic positio...
Article
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Objective The World Health Organization declared a Public Health Emergency of International Concern following the rapid emergence of neonatal microcephaly in Brazil during the 2015–2016 Zika virus (ZIKV) epidemic. In response, a national campaign sought to control Aedes mosquito populations and reduce ZIKV transmission. Achieving adherence to vecto...
Preprint
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Musculoskeletal conditions, including fractures, can have severe and long-lasting consequences. Higher body mass index in adulthood is widely acknowledged to be protective for most fracture sites, indicated through previous clinical and epidemiological observational research. However, the association between weight and bone health is complex and so...
Article
Full-text available
Zika virus (ZIKV) infections during pregnancy can lead to adverse neurodevelopmental and clinical outcomes in congenitally infected offspring. As the city of Recife in Pernambuco State, Brazil—the epicentre of the Brazilian microcephaly epidemic—has considerable disparities in living conditions, this study used an ecological approach to investigate...
Preprint
Full-text available
Background: Weight change is a major indicator of adverse health outcomes. This study aims to examine factors contributing to weight change over a one-year interval in midlife. Methods: Observational and one-sample Mendelian randomisation (MR) analyses were conducted to estimate effects on weight change compared to one year previously (mean age: 56...
Article
Full-text available
Background The outbreak of Zika virus in Brazil in 2015 followed the arrival of chikungunya in 2014 and a long history of dengue circulation. Vital to the response to these outbreaks of mosquito-borne pathogens has been the dissemination of public health messages, including those promoted through risk communication posters. This study explores the...
Article
Higher BMI during childhood is associated with an increased likelihood of remaining overweight later in life, leading to higher risk of developing type 2 diabetes (T2D). Using a Mendelian randomisation approach, a recent study found no evidence that childhood BMI has a direct causal effect on T2D. However, the extent to which high BMI in childhood...
Article
Full-text available
Background: Malaria remains a significant public health problem in Guinea-Bissau, West Africa. Government control measures include bed net distribution campaigns, however, local knowledge, attitudes and practices towards bed nets and malaria are uncharacterized on the remote Bijagos Archipelago. Methods: Knowledge, attitude and practice questionna...

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Project (1)
Project
The Global Vector Hub is an open access, interactive resource that not only has the capacity to transform vector research and vector control programmes, but revolutionise our preparedness and ability to respond quickly and effectively to vector-borne disease outbreaks, around the world. https://globalvectorhub.lshtm.ac.uk/