Gottfried Lemperle

Gottfried Lemperle
University of California, San Diego | UCSD · Division of Plastic Surgery

Professor

About

291
Publications
583,169
Reads
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4,226
Citations
Citations since 2016
61 Research Items
1295 Citations
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2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
2016201720182019202020212022050100150200
Introduction
Medical Exam in Kiel, Germany 1960. Experimental Surgery at Yale and Freiburg 1964-1971.Plastic Surgeon in Frankfurt 1971-1998 and at UC San Diego 1998-2013. Chief Scientific Officer of Artes Medical, Inc. San Diego 1998-2006, and of AscentX Medical, Inc., San Diego 2009-present. Chief Medical Officer of Hafod Bioscience, B.V. in Guangzhou 2006-present.
Additional affiliations
August 1998 - July 2013
University of California, San Diego
Position
  • Voluntary Professor
May 1974 - July 1998
Goethe-Universität Frankfurt am Main
Position
  • Teaching Professor
Description
  • Teaching Reconstructive Aesthetic Plastic Surgery

Publications

Publications (291)
Article
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Background and study design: Bulking agents are currently not available for the treatment of gastroesophageal reflux disease (GERD) and only play a secondary role in the treatment of stress urinary incontinence (SUI) and fecal incontinence (FI). The main reasons for their reluctant use are a relatively high rate of reported adverse events with curr...
Article
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(1) Background: Protruding ears are the most common auricular malformation affecting approximately 5% of the population. One common factor leading to auricular protrusion is a deficiency or total absence of the antihelix. A technique first described by Gottfried Lemperle in 2003 attempts cartilage thinning, folding, and fixation by non-absorbable m...
Article
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An increasing number of soft tissue filler substances have been introduced to the beauty market outside the U.S. which lackexperimental and clinical data in support of their claim. Ten commercially available filler substances were examined for biocompatibility and durability: 0.1 cc of each substance was injected deep intradermally into the volar f...
Article
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The reason for these simple tests was the lack of knowledge on the effects and reactions of surging dermal fillers in 2003. How can we as physicians inject any dermal filler not knowing what histologic reactions it causes in the dermis and beneath? What is the mechanism of its absorption, and how long does it last? Does a filler remain where it is...
Article
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Langer’s lines are still the recommendation and matrix for surgical incisions in most surgical textbooks, even if they were never meant to be by their first describer in 1861. To achieve minimal scarring, surgeons should attempt to make incisions parallel to skin tension lines, i.e., in skin folds or skin creases. On the basis of visible stretch ma...
Article
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Of huge importance now is to provide a fast, cost-effective, safe, and immediately available pharmaceutical solution to curb the rapid global spread of SARS-CoV-2. Recent publications on SARS-CoV-2 have brought attention to the possible benefit of chloroquine in the treatment of patients infected by SARS-CoV-2. Whether chloroquine can treat SARS-Co...
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Abstract A better knowledge of the SARS-CoV-2 virus and its underlying pathobiology is accumulating every day. Of huge importance now is to provide a fast, cost effective, safe, and immediately available pharmaceutical solution to curb the rapid global spread of SARS-CoV-2. This Opinion discusses the demands for such an ideal drug and taking into a...
Article
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Lemperle G. et al. Keloids: Which Types Can Be Excised without Risk of Recurrence? A New Clinical Classification. Background: A surgical team from Interplast-Germany removed 387 keloids in 302 patients during 4 visits to Goma, Democratic Republic of the Congo, from 2015-2018. Preoperative and postoperative photographs and a thorough anamnesis of ke...
Chapter
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Microspheres of polymethylmethacrylate (PMMA) have been injected beneath wrinkles and for facial volume augmentation since 1990 in more than 500,000 patients worldwide. They remain in the body permanently and are as safe as hyaluronic acid injections if injected strictly subdermally and epiperiosteally. Most serious complications occur after intra-...
Article
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Background: ALK-positive Anaplastic Large-Cell Lymphomas (ALCL) are chemo-sensitive cancers; combination of histologic and immunophenotypic or genetic studies remains the main strategy to prevent their unnecessary surgical excision as they can mimic soft tissues sarcomas in histology. In sub- Saharan Africa, however, availability and affordability...
Article
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An estimated 1000 patients worldwide, who develop foreign body granulomas after the injection of all kinds of dermal fillers, are treated falsely with systemic antibiotics over several months – just because one pathologist claimed to have found the reason for granulomas in a local bacterial infection. The problem is the easiness today how authors c...
Article
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Gastric Reflux Disease: Minimal Invasive Treatment Options, an Overview Gottfried Lemperle, Stefan M. Lemperle, Abstract Gastric Reflux (GERD) represents one of the most prevalent medical conditions in society. Pharmaceutical and invasive surgical treatments of reflux are readily available with good results in most cases. However, medications don'...
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Background: Patients, particularly those who are young, often develop noticeable orthopaedic scars. In order to achieve minimal scarring, surgeons should attempt to place incisions in skinfolds or skin creases. Methods: Optimal incision lines can be determined from the direction of stretch marks (striae distensae), which develop perpendicular to...
Data
Ein auffälliges Down´Gesicht kann durch kleinere, in der plast. Chir. übliche Korrekturen wie Geraderichten der Lidspalte, Anheben des Nasenrückens, Keilexzision aus der Zunge, ein Kinn-Implantat und Absaugen des Halses ansprechender gestaltet werden - - nicht für das Kind, sondern für dessen Eltern ! Trotzdem scheint ein unauffälligeres Aussehen d...
Chapter
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Bei KIndern mit Down-Syndrom kann das Aussehen mit kleinen, in der plastischen Chirurgie üblichen Korrekturen verbessert werden: Geraderichten der Lidspalte, Anheben des Nasenrückens, Keilexzision aus einer großen Zunge, Kinn-Implantat und Absaugen des Halses - Obwohl es für die Eltern getan wird, erleichtert es die Entwicklung des Kindes (Ron Wexl...
Chapter
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The appearance of the female breast depends not only on its volume and nipple areola complex , but also a great deal on the submammary fold, which allows a certain overhanging of the breast. The first postmastectomy reconstructions using silicone prostheses were described by Snyderman in l97l (13) and Lewis (6,7) The prostheses were gel-filled impl...
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surgical incisions result in fine scars when cut in main folding lines
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Mit dem Wiederaufbau der weiblichen Brust begannen wir l97l in unserer Klinik mit einer vergleichsweise umständlichen Methode : dem ge stielten Unterb auch-lappen (5). Dieser sogenannte ,pancake-flap" war bereits 1942von GILLIES,1955 von DE CHOLNOCKY und 1976 von MILLARD beschrieben worden. Bei unseren ersten l5 Patientinnen entstan-den nach 8-16 o...
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Breast Nipple Reconstruction - different possibilities
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Cold water therapy and antibiotic creams save rats from death after 3rd degree burn
Chapter
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In children with Down-Syndrome, facial features can be improved by common small surgical procedures
Article
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Das kosmetische Resultat einer Reduktions-Mammapla-stik steht und fäIlt mit der Position der Mamillen. Nach jeder operativen Verkleinerung oder Straffung senkt sich die Brust aufgrund der Narbenresorption und physiologi-schen Dehnung der Haut. Während diese normale Ptosis bei den verschiedenen Operationsmethoden berücksich-tigt wird, kommt es bei e...
Chapter
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Since Patey and Dyson (8) showed that breast amputation could be performed adequately via a horizontal incision, and since Crile (2), Fisher (4), and Veronesi.(11) showed with large statistical studies that the long-term results depend on the tumor stage at the time of surgery rather than on the extent of surgery, plastic surgeons were then able to...
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Einführung ,,Bigger is better" schwirrt in den Köpfen vieler Männer herum, auch wenn es sich um ihr bestes Stück handelt. Die \Terbeindu-strie hämmert es uns täglich ein, wenn es um Mode, Autos und selbst um Ernährung geht. Und hier tut die Pornoindustrie noch ein Übriges: den Druck auf die Männer erhöhen, ihre Erscheinung und ihre Leistung optimie...
Chapter
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In elderly patients who are bothered by their "turkey gobbler", a vertical skin excision can solve the problem in 30 minutes.
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In protruding ears, the shape of the anti helix can be formed much smoother and better with a dermabrador from an anterior skin incision along the scapha.
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Ein unbekannter Prozentsatz von Männern wird jedes Risiko auf sich nehmen, um einen größeren Penis zu bekommen. In der Vergangenheit wurden weltweit alle möglichen Flüssigkeiten oder Gele meist in Eigeninjektionen unter die Haut des Penis gespritzt – mit meist desaströsen Folgen. Auch alle zugelassenen injizierbaren „medizinischen Produkte“ haben b...
Article
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When the skin cover is sufficient thick, silicone implants can provide fast and safe augmentation of the facial bones.
Article
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The depression of most funnel chest deformities can easily be filled with a custom-made RTV-silicone implant on the operating table.
Chapter
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slim calves with a lack of contour can easily be augmented with prefabricated solid or soft silicone implants. The contour with solid implants is more natural.
Chapter
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Up to today, the effect of total removal of both gastrocnemius muscles is still far superior to only nerve or head excisions - and has not shown any problems in static or sports.
Article
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Background: Considering that aesthetic benefits can be obtained with the use of permanent filling materials, this work focuses on the development of a consensus regarding the facial and corporal use of polymethylmethacrylate (PMMA) filler in Brazil. Methods: A questionnaire regarding PMMA treatment, which included items on the main indication, a...
Article
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Brazilian Consensus Recommendation on the Use of Polymethylmethacrylate Filler in Facial and Corporal Aesthetics Tulio Armanini Blanco Souza Letıcia Marques Colome´ Eduardo Andre´ Bender Gottfried Lemperle Aesthetic Plast Surg. 2018 Oct;42(5):1244-1251. Background Considering that aesthetic benefits can be obtained with the use of permanent filling...
Chapter
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Men are often concerned about their beginning "turkey gobbler" under the chin and want to get rid of it. Most often, a facelifting procedure is not indicared. Skin which you can grab, you can excise. Therefore, a simple vertical oval removal of the excess skin is advised and can be performed under local anesthesia. Even if the scar runs against the...
Article
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Commentary to: "Neck rejuvenation by direct anterior medial cervicoplasty: the modified zigzag-plasty according to Tschopp" JEADV 2018; DOI: 10.1111/jdv.14776 By Gottfried Lemperle, MD, PhD, plastic surgeon, Frankfurt am Main, Germany Unquestionably, most elderly are less concerned about their face than about their “turkey gobbler” neck (see Ref.9)...
Article
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Though the incidence of complications and adverse events with dermatological fillers is inherently low, practitioners should be well versed in both prevention of filler complications and the treatment algorithms for addressing “granulomas,” nodules, infection, and vascular compromise. Appropriate preventative measures, coupled with timely and effec...
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Biocompatibily of Injectable Microspheres A review of the literature Gottfried Lemperle, M.D., Ph.D. *From the Division of Plastic Surgery, University of California, San Diego, Abstract The increasing need for long lasting injectable soft tissue fillers for the treatment of wrinkles and skin defects, gastric reflux, urinary and fecal incontinence...
Article
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Biocompatibility of Injectable Microspheres Gottfried Lemperle, M.D., Ph.D. Division of Plastic Surgery, University of California, San Diego, CA Abstract The increasing need for long lasting injectable soft tissue fillers for the treatment of wrinkles and skin defects, gastric reflux, urinary and fecal incontinence, and other indications requires...
Article
Artecoll is the only permanent dermal filler to be approved by the European Union and China Food and Drug Administration, and has been used worldwide since 1994 in approximately 400,000 patients. Since 2002, Artecoll-4 has also been injected in China in more than 42,000 patients in more than 100 hospitals, primarily for beauty refinement in younger...
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A 14-month-old Nepalese infant had developed a rapidly growing facial tumor originating from a dark spot on her upper eyelid. A cavernous hemangioma was suspected and treated with high doses of propranolol and prednisolone. Remission was dramatic. Histology confirmed alveolar rhabdomyosarcoma. Chemotherapy was planned but not carried out due to com...
Article
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] A Retrospective Evaluation of the Safety and Effectiveness of the Penuma Silicone Implant for Elective Cosmetic Surgery of the Penis Elist, J.; Lemperle, G.; Mirgoli, O.; Hosseini, A. 1: Cedars-Sinai Medical Center, Los Angeles, CA; 2: Division of Plastic Surgery, University of California, San Diego, CA Abstract. Aim. This retrospective rev...
Article
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Introduction: An unknown percentage of men will take every risk to develop a larger penis. Thus far, most injectables have caused serious problems. Polymethylmethacrylate (PMMA) microspheres have been injected as a wrinkle filler and volumizer with increasing safety since 1989. Aim: To report on a safe and permanently effective method to enhance...
Article
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In an effort to achieve inconspicuous scars, plastic surgeons try to place their incisions in established creases and folds of the skin. While well established in the face and abdomen, these folding lines are often disputable on other parts of the body. We examined photographs of 213 individuals with striae and a composite diagram was created. This...
Article
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Einleitung: Zielsetzung der vorgestellten Lippenrekonstruktion ist der Funktionsaufbau und die Wiederherstellung der Ästhetik unter eingeschränkten Operationsbedingungen im Auslandseinsatz. Es werden 2 Fälle aus der demokratische Republik Kongo vorgestellt. Marodierende Soldaten hatten 2 jungen Männern Ober- und Unterlippen, Ohren und Finger abgesc...
Research
folded breast implants may be thinning out the overlaying skin by their pointed edges
Article
Full-text available
In an effort to achieve inconspicuous scars, plastic surgeons try to place their incisions in established creases and folds of the skin. While well established in the face and abdomen, these folding lines are often disputable on other parts of the body.We examined photographs of 213 individuals with striae and a composite diagram was created. This...
Chapter
Full-text available
the only proven method for predictable penile enlargement
Article
In an effort to achieve inconspicuous scars, plastic surgeons try to place their incisions in established creases and folds of skin. Although well established in the face and abdomen, these folding lines are often disputable on other parts of the body. Striae distensae always develop perpendicular to lines of tension, and their direction can be use...
Article
Full-text available
The present article focuses on the peculiarities of polymethylmethacrylate as facial filler highlighting the injection technique, known adverse effects, and all options for complication management. Supplemented by a historical overview and case series, the authors share their experience with this widespread and in the last decade heavily criticized...
Article
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Penile prosthesis surgery for erectile dysfunction has the highest satisfaction rates among all treatment options but is often associated with subjective and objective loss of penile length and girth following surgery. To present a novel technique using a subcutaneous soft silicone implant for reversal of penile shortening and narrowing after prost...
Article
Endoscopic therapy for GERD is an appealing, minimally invasive alternative to medical treatment and surgery. Various materials have been tested to augment the lower esophageal sphincter (LES), with limited success. To our knowledge, safety and migration of polymethylmethacrylate (PMMA) microspheres has never been evaluated. To assess the safety, m...