Gokce Laleci

Gokce Laleci
SRDC Ltd

PhD

About

100
Publications
24,329
Reads
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1,810
Citations
Citations since 2017
29 Research Items
430 Citations
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2017201820192020202120222023020406080100
2017201820192020202120222023020406080100

Publications

Publications (100)
Conference Paper
Introduction: CAREPATH is an Horizon 2020 funded project aiming to generate a digital health solution, supported by an information and communication technology infrastructure, for care based on the current best practice guidelines, optimizing it for specific regions and health systems, for treatment and management of multimorbid patients with mild...
Conference Paper
Full-text available
The process of developing a computer interpretable, integrated clinical guideline requires multiple considerations and decisions. As part of the CAREPATH project, a holistic approach to comorbidity has been adopted using an integrated clinical guideline for the management of multimorbid patients with mild cognitive impairment or mild dementia. The...
Conference Paper
Full-text available
Management of multiple chronic conditions introduces demanding challenges for patients. This situation becomes more complex when multimorbidity is associated with dementia. In this paper, we present the design of a mobile Patient Empowerment Platform that enables older multimorbid patients with mild dementia or mild cognitive impairment (MCI) to ea...
Chapter
In the health care sector, person-centred treatment approaches have shown the potential to improve treatment outcomes and quality of life of patients. In particular, this applies where patients are living with complex conditions like multimorbid older patients with Mild Cognitive Impairment (MCI) or mild dementia. Such treatment approaches quite of...
Article
Full-text available
CAREPATH project is focusing on providing an integrated solution for sustainable care for multimorbid elderly patients with dementia or mild cognitive impairment. The project has a digitally enhanced integrated patient-centered care approach clinical decision and associated intelligent tools with the aim to increase patients' independence, quality...
Article
Full-text available
Modern healthcare providers rely upon Electronic Healthcare Records (EHR) systems to record patient data inside their own organization. Some healthcare providers share this data to facilitate patient care with other providers. Medical devices and healthcare providers can use differing standards of recording healthcare information. The Structural an...
Chapter
Full-text available
Chronic diseases introduce challenges for the patients to manage the changing requirements of the disease. Patient empowerment activities are a critical component to assist patients in their long-term care journey. In order to be effective, patient empowerment tools need to be well-integrated with the chronic disease management tools used at the cl...
Preprint
BACKGROUND There is an increasing need to organise the care around the patient and not the disease, as well as taking into account the complex realities of multiple physical, psycho-social conditions and polypharmacy. Integrated patient-centred care delivery platforms have been developed for both patients and clinicians. These platforms could provi...
Article
Background: There is an increasing need to organize the care around the patient and not the disease, while considering the complex realities of multiple physical and psychosocial conditions, and polypharmacy. Integrated patient-centered care delivery platforms have been developed for both patients and clinicians. These platforms could provide a pr...
Article
Full-text available
Background: C3-Cloud is an integrated care ICT infrastructure offering seamless patient-centered approach to managing multimorbidity, deployed in three European pilot sites. Challenge: The digital delivery of best practice guidelines unified for multimorbidity, customized to local practice, offering the capability to improve patient personalizatio...
Article
Full-text available
Background FAIR (findability, accessibility, interoperability, and reusability) guiding principles seek the reuse of data and other digital research input, output, and objects (algorithms, tools, and workflows that led to that data) making them findable, accessible, interoperable, and reusable. GO FAIR - a bottom-up, stakeholder driven and self-gov...
Article
Full-text available
Supported by the European Commission under Horizon 2020, mHealth4Afrika is co-designing and validating a modular, multilingual, state-of-the-art health information system addressing primary healthcare requirements in resource constrained environments. mHealth4Afrika has co-designed a comprehensive range of functionality and medical programs in part...
Article
Full-text available
Introduction: A growing share of the population in OECD countries is of age 65 and over, expected to reach 22% by 2030 (compared to 15% in 2010). Life expectancy has also significantly increased. People at age of 65 are expected to live for an average of 21 and 17 years for women and men; an almost 40% increase since 1960. The profound success in i...
Article
This paper provides a summary of the Privacy Management Analysis method followed for the analysis of the International Patient Summary exchange use cases of Trillium II Project. The objective is to recommend the required security and privacy measures by providing traceability from Regulations/Principles/Preferences to the recommended Security & Pri...
Article
Full-text available
Older age is associated with an increased accumulation of multiple chronic conditions. The clinical management of patients suffering from multiple chronic conditions is very complex, disconnected and time-consuming with the traditional care settings. Integrated care is a means to address the growing demand for improved patient experience and health...
Article
Full-text available
mHealth4Afrika has introduced the use of CE approved medical sensors at the point of care in primary healthcare facilities in Africa as part of an integrated platform supporting primary health care services. This paper shares insights into the standards-based architecture and HL7 FHIR service developed to support data transfer from sensors with pro...
Article
Full-text available
Objective We aim to deliver a framework with 2 main objectives: 1) facilitating the design of theory-driven, adaptive, digital interventions addressing chronic illnesses or health problems and 2) producing personalized intervention delivery strategies to support self-management by optimizing various intervention components tailored to people’s indi...
Article
Full-text available
Background: Utilization of the available observational healthcare datasets is key to complement and strengthen the postmarketing safety studies. Use of common data models (CDM) is the predominant approach in order to enable large scale systematic analyses on disparate data models and vocabularies. Current CDM transformation practices depend on prop...
Article
Older age is associated with an increased accumulation of multiple chronic conditions. The clinical management of patients suffering from multiple chronic conditions is very complex, disconnected and time-consuming with the traditional care settings. Integrated care is a means to address the growing demand for improved patient experience and health...
Chapter
Full-text available
This paper describes how semantic interoperability can be achieved in emergency management domain where different organizations in different domains should communicate through a number of distinct standards to manage crises and disasters effectively. To achieve this goal, a common ontology is defined as lingua franca and standard content models are...
Article
Full-text available
Depending mostly on voluntarily sent spontaneous reports, pharmacovigilance studies are hampered by low quantity and quality of patient data. Our objective is to improve postmarket safety studies by enabling safety analysts to seamlessly access a wide range of EHR sources for collecting deidentified medical data sets of selected patient populations...
Conference Paper
In this study, we address two major problems of spontaneous reporting systems for adverse drug events (ADEs): underreporting and low report content quality. In the scope of WEB-RADR project, we make use of relevant patient information available in electronic health record (EHR) systems to facilitate ADE reporting process and promote spontaneous rep...
Article
Full-text available
Postmarketing drug surveillance is a crucial aspect of the clinical research activities in pharmacovigilance and pharmacoepidemiology. Successful utilization of available Electronic Health Record (EHR) data can complement and strengthen postmarketing safety studies. In terms of the secondary use of EHRs, access and analysis of patient data across d...
Article
Full-text available
This article is part of the Focus Theme of Methods of Information in Medicine on "Managing lnteroperability and Complexity in Health Systems". Background: SALUS project aims at building an interoperability platform and a dedicated toolkit to enable secondary use of electronic health records (EHR) data for post marketing drug surveillance. An impor...
Article
Adverse drug events (ADEs) are common, costly and one of the most important issues in contemporary pharmacotherapy. Current drug safety surveillance methods are largely based on spontaneous reports. However, this is known to be rather ineffective. There is a lack of automated systems checking potential ADEs on routine data captured in electronic he...
Article
Full-text available
Use of medical terminologies and mappings across them are considered to be crucial pre-requisites for achieving interoperable eHealth applications. Built upon the outcomes of several research projects, we introduce a framework for evaluating and utilizing terminology mappings that offers a platform for i) performing various mappings strategies, ii)...
Article
Full-text available
Objectives: The objective of this paper is to describe some of the major healthcare information technology (IT) infrastructures in Turkey, namely, Sağlık-Net (Turkish for "Health-Net"), the Centralized Hospital Appointment System, the Basic Health Statistics Module, the Core Resources Management System, and the e-prescription system of the Social...
Conference Paper
Adverse drug events (ADEs) are common, costly and a public health issue. Today, their detection relies on medical chart review and spontaneous reports, but this is known to be rather ineffective. Along with the increasing availability of clinical patient data in electronic health records (EHRs), a computer-based ADE detection has a tremendous poten...
Article
Full-text available
Integration profiles collaboratively developed by CDISC and IHE for integrating data from Electronic Health Records (EHRs) with clinical research and pharmacovigilance are limited to resolving lexical/syntactic data integration issues and do not address semantic barriers. This paper describes the collaboration between two European projects - EHR4CR...
Technical Report
Full-text available
This report describes the second release of the semantic mediation framework prototype developed to support the semantic interoperability between the clinical research and clinical care systems of the SALUS project. The deliverable itself is the set of tools and services developed to create the semantic mediation framework prototype. For each of th...
Article
The goal of the keyCRF project is the creation of a semantically annotated electronic Case Report Form (eCRF) that can enable the pre-population of the eCRF from data elements in an EHR summary document through the use of semantically linked Common Data Element definitions across care and research domains.
Conference Paper
Full-text available
This work aims to demonstrate the interoperability framework developed in the SALUS project which enables effective integration and utilization of EHR data to reinforce post-market safety activities.
Article
In order to enable secondary use of Electronic Health Records (EHRs) by bridging the interoperability gap between clinical care and research domains, in this paper, a unified methodology and the supporting framework is introduced which brings together the power of metadata registries (MDR) and semantic web technologies. We introduce a federated sem...
Article
Full-text available
EHRs can now be adapted to integrate seamlessly with existing research platforms. However, key challenges need to be overcome in order to provide a platform that functions across many EHR systems. The IHE Quality, Research and Public Health (QRPH) domain addresses the information exchange standards necessary to share information relevant to quality...
Article
With this work, we demonstrate SALUS Patient History Tool which presents patient summaries to the clinical researcher by retrieving the values of the patient data fields from the semantic instances which come in the form of SALUS Common Information Model. The tool makes use of the SALUS Common Data Elements to extract the corresponding data from th...
Article
Full-text available
Improving the efficiency with which clinical research studies are conducted can lead to faster medication innovation and decreased time to market for new drugs. To increase this efficiency, the parties involved in a regulated clinical research study, namely, the sponsor, the clinical investigator and the regulatory body, each with their own softwar...
Conference Paper
Full-text available
Pre-approval clinical trials cannot guarantee that drugs will not have serious side effects after they are marketed. Post-approval drug safety data studies aim to address this problem, however, their effectiveness is started to be discussed especially after recent examples of drug withdrawals. This is due to the fact that, current post market safet...
Article
Patient Empowerment engages individuals in taking care of their own health. This has been identified as a key element of change for improved quality and safety in healthcare. In the iCARDEA project, we aim at enabling cardiovascular implantable electronic device (CIED) patients to take a more active role in their own healthcare management by offeri...
Conference Paper
Remote monitoring and follow-up of cardiac implantable electronic devices (CIEDs) introduces novel patient-focused and information-driven models of care. In this context, iCARDEA employs guideline-driven personalized care plans that use information from personal health records, hospital-based medical records, and CIED reports from remote follow-up...
Article
The reasons behind adverse drug events (ADE) getting underreported by medical professionals are overlooking complex drug reactions and dealing with cumbersome manual process of reporting ADE based on patient profiles. We present an initial design of SALUS ICSR reporting tool that supports the reporting of ADE to regulatory authorities with services...
Article
For patients with Cardiovascular Implantable Electronic Devices (CIEDs), telemonitoring promises improved quality of life and safety, since events recorded by the device or observed by the patient can alert a health professional. Taking into account the latest clinical guidelines when responding to such alerts, is a topic of active research address...
Chapter
The SAPHIRE project aimed to develop an intelligent healthcare monitoring and decision support system on a platform integrating the wireless medical sensor data with hospital information systems. In this paper one of the two demonstrator environments—the homecare scenario—is described from the medical and technical point of view. A retrospective vi...
Article
Full-text available
Cardiovascular Implantable Electronic Devices (CIED) are gaining popularity in treating patients with heart disease. Remote monitoring through care management systems enables continuous surveillance of such patients by checking device functions and clinical events. These care management systems include decision support capabilities based on clinica...
Technical Report
The intelligent bathroom use case represents a "far out" vision of IKS for direct user interactions with embedded contents that are organized by a "Semantic CMS Technology Stack". This case combines advanced content and knowledge management with an ubiquitous computing scenario in a place everybody is familiar with - the bathroom. The use case show...
Article
One of the goals of iSURF project is creating an interoperability platform in order to enable the exchange of planning data between enterprises and especially across domains. The interoperability platform of iSURF is named iSURF Interoperability Service Utility (iSURF ISU). Interoperability should be regarded as a service that users can utilize any...
Article
One of the key challenges in supply chain collaboration is to improve the efficiency and effectiveness of the suplly chain planning process to handle rapidly changing customer demands. Trading partners usually have different competencies based on their business strategies and investments. They have varying sources of information and also dissimilar...
Article
The users of a content repository express the semantics they have in mind while defining the content items and their properties, and forming them into a particular hierarchy. However, this valuable semantics is not formally expressed, and hence cannot be used to discover meaningful relationships among the content items in an automated way. Although...
Conference Paper
Full-text available
Patient empowerment frameworks engage citizens in their healthcare. Heart patients undergo implantation of Cardiovascular Implantable Electronic Devices (CIEDs) that support remote monitoring hoping to live a longer healthier life. Electronic Health Records (EHR), remote device monitoring, and lifestyle data can supply patient context to computeriz...
Article
Full-text available
Clinical guidelines are developed to assist healthcare practitioners to make decisions on patient's medical problems, and as such they communicate with external applications to retrieve patient data to initiate medical actions through clinical workflows, and transmit information to alert/reminder systems. The interoperability problems in the health...
Conference Paper
One of the key challenges in supply chain collaboration is to improve the efficiency and effectiveness of the suplly chain planning process to handle rapidly changing customer demands. Trading partners usually have different competencies based on their business strategies and investments. They have varying sources of information and also dissimilar...
Article
Currently in the travel domain most of the travel products are sold through Global Distribution Systems (GDSs). Since only major airline companies or hotel chains can afford to join GDSs, it is difficult for small and medium enterprises to market their travel products. In this paper, we describe a middleware, called SATINE, to address this problem....
Chapter
Full-text available
Due to increasing percentage of graying population and patients with chronic diseases, the world is facing serious problems for serving high quality healthcare services to citizens at a reasonable costs. In this paper, we are providing a Clininical Desicion Support system for remote monitoring of patients at their homes, and at the hospital to decr...
Article
As a response to the challenge of providing high-quality healthcare services with reasonable costs while the elderly population and the associated chronic diseases increase, SAPHIRE architecture provides an intelligent healthcare monitoring architecture. The monitoring of patients is achieved through a clinical decision support system based on clin...
Article
Full-text available
One of the key problems in healthcare informatics is the inability to share patient records across enterprises. To address this problem, an important industry initiative called "integrating the healthcare enterprise (IHE)" specified the "cross enterprise document sharing (XDS)" profile. In the IHE XDS, healthcare enterprises that agree to work toge...
Article
In this chapter we describe two case studies of Semantic Web Services applied in the eHealth domain. Starting from the interoperability problem, which naturally arises in distributed environments such as the healthcare systems, we briefly introduce the state of the art in eHealth standards (e.g. HL7, openEHR, etc.) and the trends towards semantic i...
Article
Full-text available
One of the key problems in healthcare informatics is the lack of interoperability among different healthcare information systems. Interoperability can be investigated in different categories in the eHealth domain, such as the interoperability of the messages exchanged between healthcare applications, interoperability of Electronic Healthcare Record...
Chapter
In this chapter, we describe an infrastructure enabling archetype-based semantic interoperability of Web service messages exchanged in the health care domain. We annotate the Web service messages with the OWL representation of the archetypes. Then, by providing the ontology mapping between the archetypes, we show that the interoperability of the We...
Article
Full-text available
Most medical information systems store clinical informa-tion about patients in proprietary format. To address the resulting interoperability problems, several electronic health record (EHR) standards that enable structured clini-cal content for the purpose of exchange are currently under development. In this article, we present a brief overview of...
Article
An essential element in defining the semantics of Web services is the domain knowledge. Medical informatics is one of the few domains to have considerable domain knowledge exposed through standards. These standards offer significant value in terms of expressing the semantics of Web services in the healthcare domain.In this paper, we describe the ar...
Article
Full-text available
Using archetypes is a promising approach in providing se- mantic interoperability among healthcare systems. To real- ize archetype based interoperability, the healthcare systems need to discover the existing archetypes based on their se- mantics; annotate their archetypes with ontologies; compose templates from archetypes and retrieve corresponding...
Conference Paper
Full-text available
The SAPHIRE project aims to develop an intelligent healthcare monitoring and decision support system on a platform integrating the wireless medical sensor data with hospital information systems. In the SAPHIRE project, patient monitoring will be achieved by using agent technology where the "agent behaviour" will be supported by intelligent clinical...
Chapter
In this chapter, we describe an infrastructure enabling archetype-based semantic interoperability of Web service messages exchanged in the health care domain. We annotate the Web service messages with the OWL representation of the archetypes. Then, by providing the ontology mapping between the archetypes, we show that the interoperability of the We...
Article
Full-text available
Medical information systems today store clinical information about patients in all kinds of proprietary formats. To address the resulting interoperability problems, several Electronic Healthcare Record standards that structure the clinical content for the purpose of exchange are currently under development. In this article, we present a survey of t...
Article
In this article, we describe an infrastructure enabling archetype-based semantic interoperability of Web Service messages exchanged in the health care domain. We annotate the Web Service messages with the OWL representation of the archetypes. Then, by providing the ontology mapping between the archetypes, we show that the interoperability of the We...
Article
One of the most challenging problems in the healthcare domain is providing interoperability among healthcare information systems. In order to address this problem, we propose the semantic mediation of exchanged messages. Given that most of the messages exchanged in the healthcare domain are in EDI (Electronic Data Interchange) or XML format, we des...