Gokce Dicle Kalaycioglu- Doctor of Engineering
- Professor (Assistant) at Hacettepe University
Gokce Dicle Kalaycioglu
- Doctor of Engineering
- Professor (Assistant) at Hacettepe University
About
24
Publications
1,424
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
194
Citations
Introduction
Current institution
Additional affiliations
July 2023 - present
Publications
Publications (24)
Lyotropic non-lamellar liquid crystalline (LLC) nano-self-assemblies (including cubosomes and hexosomes) are attractive versatile platforms for encapsulation and delivery of drugs and nutritional molecules. This is due to their unique structural features and architectural arrangements that afford loading of small molecules and macromolecules having...
Breast cancer is one of the fatal diseases renowned worldwide. Chemotherapy is not sufficient for the treatment of breast cancer in a significant number of cases. In this study, we present the doxorubicin (DOX) and gold nanoparticles (AuNPs) loaded nanostructured lipid carriers (DOX+AuNPs)@NLCs, designed for dual chemo/photothermal therapy. Differe...
The biophysical interaction between the nanoparticles (NPs) and biological interfaces is vitally important due to the increasing usage of NPs in biomedical and pharmaceutical applications such as drug delivery. Several different approaches or ligands can be utilized including surfactants for the surface decoration of NPs. We used two custom-made, p...
Microcapsules (MCs), prepared using colloidal particles as shell material for assembly, are a drug-delivery system offering several advantages such as increased drug encapsulation efficiency, higher surface area, modifiable structure, and multi-functionality. Nano-in-micro ibuprofen (IBU) MCs were prepared using the layer-by-layer method for use as...
Solid lipid nanoparticles (SLN), a promising drug delivery vehicle, offer an alternative system to traditional colloidal carriers. In our study 12 new SLN formulations were fabricated via the “microemulsion (ME) method”, each leading to a different SLN size and composition. This method is a relatively easy technique and involves biocompatible condi...
Although numerous technical advances have been made in cancer treatment, chemotherapy is still a viable treatment option. However, it is more effective when used in combination with photothermal therapy for resistant breast cancer cells. This study introduces a smart drug delivery system, (DOX-OA+VERA+AuNRs)@NLC, which is designed for dual chemo/ph...
One of the most important issues in the design and preparation of drug delivery systems in the recent years is versatility which includes providing synergistic therapeutic effects and sustainability. This study uses a redox‐active ferrocenyl surfactant (FcN⁺(CH2CH3)3(CH2)10CH3, Fc(C11) where Fc is ferrocene) and pH responsive Zeolitic Imidazolate F...
Breast cancer is the most common type of cancer in women and the second cause of cancer-related deathafter lung cancer. Although the common methods used in the treatment of breast cancer are chemotherapy,radiotherapy and surgery, the search for alternative treatments continues. The leading alternative treatmentsare medicinal plants which inspire th...
An anionic and amphiphilic molecule, AQua (AQ-NH-(CH2)10COOH; where AQ is anthraquinone), which has two stimuli responsive functional-groups, can form self-assembled interfacial aggregates at the air-water interface and, their morphologies can be controlled by changing the subphase conditions such as the pH of the subphase. These interfacial morpho...
Oral administration of the drugs is considered as one of the most convenient and comfortable routes. However, an effective oral delivery of insulin still remains a challenging and elusive goal, due to bioavailability problem. The aim of our work is to develop a pH sensitive polymeric system for the oral delivery of insulin based on a poly (ϵ‐caprol...
Most cancer treatments can cause vital side effects on healthy tissues. Ascorbic acid (AA) is a water-soluble antioxidant molecule and possesses a variety of functions such as prevention of tumor proliferation and treatment of cancer. However, AA, is very sensitive to air, heat and light. Its high hydrophilicity also makes the controlled delivery d...
Recently, nanomaterial-based adhesives have arised as alternatives to be used in the industrial field or to provide the next generation of biomedical adhesives with their enhanced mechanical properties and adhesion strengths. In this work, we developed a method for achieving adhesion between two PDMA (Poly dimethylacrylamide) hydrogel surfaces by u...
Organic‐inorganic hybrid nanotubes are highly functional and interesting materials. However, their formation generally requires reducing agents, high temperatures, special procedures, organic solvents etc. Here, using a simple concept based on engineering and materials design, we fabricated stimuli‐responsive lipid‐gold hybrid nanotubes. Self‐assem...
Lipid nanotubes (LNTs) are one of the most advantageous structures for drug delivery and targeting. LNTs formed by a specially designed molecule called AQUA (AQ-NH-(CH2)10COOH (AQ: anthraquinone group) is used for drug delivery, and doxorubicin (DOX) is the drug selected. DOX and AQUA have some similarities in their molecular structures, so a signi...
