Godwin Upoki Anywar

Godwin Upoki Anywar
Makerere University · Plant Sciences, Microbiology & Biotechnology

BSc MSc PhD FUNAS

About

68
Publications
30,124
Reads
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464
Citations
Introduction
Anywar Godwin completed his PhD as a CARTA fellow at the prestigious Fraunhofer Institute for Cell Therapy & Immunology in Leipzig, Germany, The Leipzig Institute for Medical Microbiology & Virology & Makerere University, Kampala. He is an academician, author and entrepreneur. He currently lectures at the Department of Plant Sciences, Microbiology & Biotechnology at Makerere University.
Additional affiliations
January 2017 - present
Makerere University
Position
  • Principal Investigator
Description
  • Project on Enhancing the production and utilisation of aromatic crops; Cymbopogon citratus & Eucalyptus citriodora & assessment of the malaria vector repellence of their essential oils under the National Agricultural Research Organisation (NARO)
January 2015 - present
Makerere University
Position
  • Assistant Lectrer
September 2010 - January 2015
Makerere University
Position
  • Research Assistant
Education
March 2016 - January 2020
Makerere University & Fraunhoher Institute for Cell Therapy & Immunology
Field of study
  • Microbiology/Ethnopharmacology
August 2012 - January 2015
Makerere University
Field of study
  • Plant Physiology & Ethnobotany
August 2004 - January 2008
Makerere University
Field of study
  • Ethnobotany

Publications

Publications (68)
Article
Full-text available
Aims: The potential activity against Candida albicans of five commonly used medicinal plant species of Bwindi Impenetrable Forest National Park in southwestern Uganda was investigated. Study Design: The phytochemical profiles of Tetradenia riparia, Erucastrum arabicum, Plectranthus lactiflorus, Solanecio mannii and Platostoma africanum were analyse...
Article
Full-text available
Communities adjacent to Bwindi Impenetrable National Park (BINP) in South-western Uganda largely depend on traditional herbal treatment for basic health care. The aim of this study was to investigate the use of medicinal plants in the treatment of fungal infections by these communities. Data was collected using semi-structured interviews, focus gro...
Article
Full-text available
Aims: The purpose of this study was to investigate the antibacterial and antifungal properties of selected wild nutraceutical plants from Nebbi district in Uganda. Study Design: Experimental study. Place and Duration of Study: The study was carried out at the Department of Veterinary Microbiology and Parasitology, College of Veterinary Medicine, An...
Article
Full-text available
Abstract Background: An ethnobotanical study was carried out in Namungalwe Sub County, Iganga District Eastern Uganda, to document medicinal plant species used in disease management among children. Methods: Ethnobotanical data was collected through interviews with households and key informants, Focus Group Discussions and the Snow ball technique. T...
Article
Full-text available
Background Globally, diarrheal and respiratory diseases are among the main causes of mortality and morbidity. In Uganda, cities are facing proliferation of trade in herbal medicines (HM), including those for diarrhea and/or cough. Information on the economic, and the ethnopharmacological aspects of these HM is scarce, deterring the sector from achi...
Conference Paper
Full-text available
Vaccines are the most cost-effective and efficacious means of reducing the disease burden of infectious diseases. Traditionally vaccines are prepared by using an attenuated version of the pathogen or by preparing and inactivating a disease-causing organism or a suitable part of it. A novel approach to vaccine making involves the production of vacci...
Article
Full-text available
Introduction: Many people living with HIV/AIDS (PLHIV) in Uganda widely use herbal medicines. However, their toxicity and safety have not been investigated. The use of these plants can potentially cause harmful effects to the health of patients. The purpose of this study was to determine the cytotoxicity of some commonly used medicinal plant specie...
Article
Full-text available
Introduction: The Uganda National Drug Authority requires phytochemical screening, freedom from microbial contamination, and evidence of safety and efficacy of the constituent plants to register herbal products. Since Uganda has no pharmacopeia, safety, efficacy, and plant processing information are not readily available. We documented the plant m...
Article
Full-text available
Background Antimicrobial resistance is swiftly increasing all over the world. In Africa, it manifests more in pathogenic bacteria in form of antibiotic resistance (ABR). On this continent, bacterial contamination of commonly used herbal medicine (HM) is on the increase, but information about antimicrobial resistance in these contaminants is limited...
Chapter
African traditional medicine is as old as mankind. There has been a recent resurgence in the use of traditional medicine all over the world, and in Africa specifically. The term traditional medicine is usually interchangeably used with complementary medicine and alternative medicine in some countries. Although different African governments have con...
Article
Full-text available
In ethnopharmacology, scientists often survey indigenous communities to identify and collect natural remedies such as medicinal plants that are yet to be investigated pharmacologically in a laboratory setting. The Nagoya Protocol provided international agreements on financial benefit sharing. However, what has yet only been poorly defined in these...
Preprint
Full-text available
Background: Globally, diarrheal and respiratory diseases are among the top ten causes of mortality, and are the major ailments for which humans seek treatment. Kampala, the capital city of Uganda is facing a proliferation of herbalists that sell herbal medicine (HM) used to manage ailments such as diarrhea and cough. The ethnopharmacological and ec...
Article
Full-text available
Introduction: The worldwide burden of viral infections has triggered a resurgence in the search for new and more efficient antiviral drugs. Scientists are also repurposing existing natural compounds such as the antimalarial drug artemisinin from Artemesia annua L. as potential drug candidates for some of the emerging and re-emerging viral infection...
Article
Full-text available
Introduction There is widespread use of Aloe species in traditional healing practices in East Africa for a variety of diseases. Unfortunately, there is a tendency of mistakenly referring to all species of the genus Aloe as Aloe vera, despite the diversity of aloes in the region. The names for the different Aloe species in local languages are usuall...
Article
Full-text available
We investigated the potential antimalarial and toxicological effects of 16 medicinal plants frequently used by traditional healers to treat malaria, fever, and related disorders in the Greater Mpigi region in Uganda. Species studied were Albizia coriaria, Cassine buchananii, Combretum molle, Erythrina abyssinica, Ficus saussureana, Harungana madaga...
Article
Full-text available
Introduction: Despite concerns about toxicity, potentially harmful effects and herb-drug interactions, the use of herbal medicines remains widely practiced by people living with HIV/AIDS (PLHIV) in Uganda. Objective: The objective of the paper was to comprehensively review the literature on the toxicity and chemical composition of commonly used med...
Article
Full-text available
Background: In Sub-Saharan Africa, herbal therapy continues to be utilized for HIV-1 disease management. However, the therapeutic benefits of these substances remain ambiguous. To date, little is known about the effects of these plant extracts on chronic CD4 + T-cell activation and exhaustion which is partly driven by HIV-1 associated microbial tr...
Article
Full-text available
Background: In the Acholi sub-region, consumption of wild edible plants is still an integral part of the food culture, particularly during times of food shortage. However, much of indigenous traditional knowledge has not been documented due to the history of prolonged civil war in the area. We conducted an ethnobotanical survey to document the wild...
Article
Full-text available
Our study investigates 16 medicinal plants via assessment of inhibition of proinflammatory enzymes such as cyclooxygenases (COX). The plants are used by traditional healers in the Greater Mpigi region in Uganda to treat inflammation and related disorders. We present results of diverse in vitro experiments performed with 76 different plant extracts,...
Chapter
According to the World Health Organization, the global burden of neurological disorders (NDs) is projected to increase from 92 at present to 103 million Disability Life Adjusted Years (DALYs) by 2030. However, NDs are not prioritized in modern healthcare systems considering the funds allocated and the limited availability of specialized modern heal...
Article
Full-text available
In ethnopharmacological research, many field assessment tools exist. Yet, these miss that critical point of how to really determine which species merit the costly lab studies, e.g., evaluation of traditional use via pharmacological assays and isolation of bioactive secondary metabolites. This gap can be filled with the introduction of a new tool fo...
Chapter
Full-text available
Toxic or poisonous plants have both intrigued and fascinated man throughout history. They have been, and are still, shrouded in mystery and secrecy in many societies, forming the mainstay of religion and superstition. Knowledge on poisonous plants has been the preserve of a select few, such as hunters and herbalists. The historical use of toxic pla...
Article
Full-text available
Antibiotic resistance poses one of the greatest threats to global health today; conventional drug therapies are becoming increasingly inefficacious and limited. We identified 16 medicinal plant species used by traditional healers for the treatment of infectious and inflammatory diseases in the Greater Mpigi region of Uganda. Extracts were evaluated...
Article
Full-text available
Background: There are high mortality and morbidity rates due to poisonous snakebites globally with sub-Saharan Africa having some of the highest cases. However, traditional medicine practitioners (TMP) have been treating snakebites in Uganda for long despite the fact that few studies have been conducted to document such vital and rich indigenous tr...
Preprint
Full-text available
Background There is high mortality and morbidity due to poisonous snakebites globally, with Sub Saharan African having one of the highest rates. However, Traditional Medicine Practitioners (TMP) have been treating snakebites in Uganda for long. However, few studies have been conducted to document such vital traditional indigenous knowledge before i...
Article
Introduction: People living with HIV/AIDS (PLHIV) widely use medicinal plants for boosting immunity and managing infections. The aim of this study was to document the medicinal plant species used by herbalists to boost the immune system of people living with HIV/AIDS in Uganda. Materials and methods: Semi-structured questionnaires were administered...
Chapter
Plants have traditionally been used as a source lead compounds in the development of drugs. Plants have also been the source of several drugs, which are currently the main stay for the treatment of major diseases like malaria and cancer. This has led to continued research for new drugs, leading to new bioprospecting initiatives for novel lead compo...
Chapter
A number of bioactive natural products with therapeutic potential are naturally available. Drug discovery and development from these products using conventional methods is time and resource consuming. In order to improve efficiency of identifying new drugs from natural products, Computer Aided Drug Design (CADD) or in silico screening is now routin...
Article
Ethnopharmacological relevance: Currently, more than two thirds of the world's 36.9 million people living with HIV/AIDS reside in Sub-Saharan Africa. Opportunistic infections (OI) associated with HIV are the single most important cause of mortality and morbidity among HIV/AIDS patients in poor countries. There is widespread use of medicinal plant...
Article
Full-text available
This Data in Brief article provides supplementary information to or earlier Ethnobotanical survey on medicinal plants used by traditional medicine practitioners to boost the immune system in people living with HIV/AIDS in Uganda [1]. We identified 71 medicinal plant species from 37 families and 64 genera. The data were analysed using descriptive st...
Raw Data
In Uganda, herbalists widely used medicinal plants for treating people living with HIV/AIDS (PLHIV). Different species are mainly used to treat the opportunistic infections that characterise the disease. An ethnobotanical survey was conducted in eight districts of Arua, Dokolo, Mbale, Bushenyi, Iganga, Rakai, Luwero and Kaabong in different parts o...
Article
Full-text available
Background We aimed to determine the rate of herbal medicine usage and the treatment-seeking behaviour of caregivers of children under 5 years of age with presumed or confirmed malaria in in an endemic area of Uganda. Methods We interviewed parents/ guardians of 722 children aged 6 months to 5 years, who had experienced an episode of presumed mal...
Chapter
Full-text available
The production of phytochemicals is usually known to be natural in plants. Recently, the propagation techniques have taken newer paths involving the preservation of plant species that saw the advantage of further manipulation of the growth environment of the plants to suit better growth patterns. Researchers understood that similar methods can be u...
Chapter
Full-text available
Indigenous Traditional Knowledge (ITK), particularly on medicinal plants is a rich source of lead compounds for drug discovery. However, this knowledge is often shrouded in secrecy and is not well documented. Much of this knowledge is being lost each time its custodians pass away. This is largely because of the predominantly oral nature of the Afri...
Article
Full-text available
Plants are commonly used during the antenatal stage in pregnancy to manage different ailments in Africa. In Uganda, both medicinal and food plants are used to handle common pregnancy related conditions. An ethnobotanical survey was conducted in Iganga district, eastern Uganda. Seven traditional birth attendants (TBA) and 46 mothers were interviewed...
Article
Full-text available
There are high levels of malnutrition especially among children in Africa. In Uganda, this is compounded by widespread food insecurity. There are various wild edible plant species in Uganda. However, little research has been carried out to document and validate the claims associated with their use. A study was, therefore, carried out to analyse the...
Conference Paper
The majority of plant and insect species of the tropical rainforests in western Uganda and eastern Democratic Republic of Congo have not yet been discovered; 99% have not yet been screened for bioactivity. Approx. 60% of the world’s population relies almost entirely on plants for medication and knowledge of East African plants and their traditional...
Poster
Full-text available
Presented at: Technological, Industrial and Political Conference 2017 - Nutrition. In 2015, Fabien Schultz started collaboration with the Ugandan botanist Godwin Anywar, initiating a research project aiming towards the search for new bioactive molecules that may fight globally relevant diseases. This project approach is supposed to accompany Mr. Sc...
Presentation
Presented at NatuRA Research Group – Prof Luc Pieters. University of Antwerpen, Antwerpen, Belgium.
Presentation
Presented at: Leibniz-Institute of Plant Biochemistry, Halle, Germany
Chapter
Full-text available
Noncommunicable diseases (NCDs) are recent and growing health problem in Uganda. The NCDs epidemic is burdening the healthcare systems, which is already under pressure from the high prevalence of communicable diseases. Hypertension is the most common NCD in Uganda; more females than males suffer from NCDs. High blood pressure and heart disease equa...
Poster
Presented at: Celebration 25 years Neubrandenburg University of Applied Sciences
Presentation
Presented at: Lectures at Special Locations - Long night of Science, Neubrandenburg, Germany
Chapter
Currently there is no universally accepted definition of ''nutraceutical'' and "functional food". There is some degree of overlap when using these terms and some authors have them interchangeably. Whereas nutraceuticals are mainly involved in the prevention and treatment of disease, functional foods are mainly involved in disease reduction. Globall...
Article
Full-text available
In Uganda, malaria has been ranked as a leading cause of morbidity and mortality with Apac District having one of the highest transmission rates. The objective of this study was to assess the use of medicinal plants in preventing and treating malaria and to determine the traditional concept of malaria in Cegere Sub-County, Apac. A snowball sampling...
Article
Full-text available
Hernia is a common neglected disease that occurs when a portion of tissue or a body organ bulges through a weak- ened muscle area. This study was carried out to docu- ment traditional concepts of hernia and the medicinal plant species used in its treatment among Prometra Tra- ditional Medical Practitioners (TMP) in Mpigi District, cen- tral Uganda....
Article
Full-text available
Aframomum angustifolium (Sonn.) K. Schum., is a perennial herb indigenous to Uganda and is widely used for medicinal and ethnodietary purposes. The ether and methanol extracts of the ripe pod of A. angustifolium were screened for antibacterial activity against; Staphylococcus aureus (ATCC 43300), Staphylococcus aureus (ATCC 25923), Escherichia coli...
Conference Paper
Full-text available
Six plant species commonly used as nutraceuticals from Nebbi district in northwestern Uganda Erythrococca bongensis, Grewia trichocarpa, Leptadenia hastata, Nymphaea lotus, Oxygonum sinuatum and Talinum portulacifolium) were analysed for their nutritional content. The plants were selected mainly because of their high frequency of use as food and me...
Article
An ethnopharmacological survey was conducted on medicinal plant species used in the treatment of snakebites in Mukono district, central Uganda, between February and May 2014. Interviews were held using questionnaires and Focus Group Discus- sions. Data was collected from Herbalists, school children and households who had been afflicted by snakebite...
Article
Full-text available
Aims: To inventory the wild plant species used both as food and medicine and how they are used in Panyago Sub County, Nebbi district. Study Design: Ethnobotanical study. Place and Duration of Study: The villages of Kaal, Padoch South, Nyakaduli and Pacer South, Panyango Sub County, Jonam County in Nebbi district, between May and July 2011. Methodol...
Article
Full-text available
Aims: The purpose of this study was to investigate the antibacterial and antifungalproperties of selected wild nutraceutical plants from Nebbi district in Uganda. Study Design: Experimental study. Place and Duration of Study: The study was carried out at the Department of VeterinaryMicrobiology and Parasitology, College of Veterinary Medicine, Anim...
Conference Paper
Full-text available
An ethnobotanical study was conducted to inventory the wild plant species used as both food and medicine and how they are used in Panyago Sub County, Nebbi district, Uganda. Data were collected using questionnaires; focus group discussions and field observations. Both purposeful sampling methods and simple random sampling methods were used to obtai...

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There is a seminal work with over 5000 anticancer agents from plants/nature but I can't remember the title or author. Can anyone please share?

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Projects

Projects (11)
Project
To document medicinal plants used in the treatment of diabetes. This project will be the foundation for further research in discovering potential antidiabetic drugs.
Project
To provide a detailed and comprehensive up to date book on the priority and important medicinal plant species of Uganda