Gloria Cimaglia

Gloria Cimaglia
Cardiff University | CU

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8
Publications
993
Reads
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40
Citations
Additional affiliations
October 2019 - October 2022
Karolinska Institutet
Position
  • .

Publications

Publications (8)
Article
Full-text available
Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal levels of NAD decline. We assess the effects of nicotinamide (a precursor to NAD) on retinal ganglion cells (the affected neuron in glaucoma) in normal physiological conditions...
Preprint
Full-text available
Nicotinamide adenine dinucleotide (NAD) is a REDOX cofactor and metabolite essential for neuronal survival. Glaucoma is a common neurodegenerative disease in which neuronal levels of NAD decline. Repleting NAD via dietary supplementation of nicotinamide (a precursor to NAD) is effective in preventing retinal ganglion cell neurodegeneration in mouse...
Article
Full-text available
Glaucoma and age-related macular degeneration are leading causes of irreversible blindness worldwide with significant health and societal burdens. To date, no clinical cures are available and treatments target only the manageable symptoms and risk factors (but do not remediate the underlying pathology of the disease). Both diseases are neurodegener...
Article
Full-text available
Nutraceuticals had always been known for their therapeutic effects in ancient medicine and had been the primary healing remedy until the introduction of modern chemistry and pharmacology. However, their use has not been dismissed but actually is acquiring a new acclamation among the scientific community especially for their efficacy on the Central...
Conference Paper
Neural stem cells (NSCs) proliferation and differentiation play a pivotal role in the generation of functional neuronal networks. However, NSCs as they develop and acquire the features of a mature neuronal phenotype progressively lose their ability to proliferate. Here we demonstrate that Ruta graveolens aqueous extract (R. graveolens a.e.), which...

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