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Publications (18)
Microreactor technology applied in continuous flow processing is an essential feature in making organic synthesis more economical and environmentally friendly. On the other hand, microwave-assisted chemistry is a key technique that has made a significant contribution to the thermal control of synthetic reactions in the early 90's by speeding up rea...
We have been studying the development of new asymmetric two-center catalysis using rare earth alkoxides and bifunctional sugar
and related ligands. In The Fourth International Conference on Multi-Component Reactions and Related Chemistry (MCR 2009),
new catalytic asymmetric reactions using catalysts 1 and 2 and catalytic asymmetric syntheses of ran...
Thin-gold films have been laid down on the inner surface of borosilicate capillaries using a variety of deposition techniques
and the resultant film composition and morphology has been evaluated using energy-dispersive x-ray (EDX) and scanning electron
microscopy (SEM) analysis, respectively. These films have been shown to couple very strongly with...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Temperatures can exceed 900 °C when a strongly microwave-conducting thin-metal film is irradiated. In the Full Paper by M. G. Organ and C.-J. Li et al. on page 126 ff., Au and Cu films have been shown to be very proficient at catalysing the three-component coupling of terminal alkynes, amines, and aldehydes to produce propargyl amines.
An effective multi-component reaction (MCR) protocol has been developed for the construction of propargyl amines from aldehydes, amines and terminal alkynes by using microwave-assisted continuous-flow organic synthesis (MACOS). The process is catalysed by thin films of either copper or gold that achieve temperatures in excess of 900 degrees C when...
Methodology has been developed for laying down a thin gold-on-silver film on the inner surface of glass capillaries for the purpose of catalysing benzannulation reactions. The cycloaddition precursors are flowed through these capillaries while the metal film is being heated to high temperatures using microwave irradiation. The transformation can be...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Thin gold films on the surface of glass capillaries have proven to be highly active catalysts for the rapid hydrosilylation of alkynes that are flowed through the reactor while being heated by microwave irradiation. The films are able to be reused at least five times with no loss of activity and with no detectable levels of gold showing up in the h...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Thin Pd films have been deposited on the inside of capillary-sized tubes through which compounds undergoing Diels-Alder reactions have been flowed while being heated with microwave irradiation; dramatic rate accelerations are observed in the presence of the film, which has been shown to play both a heating and catalytic role.
A method has been devised for the microwave-assisted, continuous-flow preparation of indole alkaloids by a two-step aryl amination/cross-coupling sequence of bromoalkenes and 2-bromoanilines. This process requires both the presence of a metal-lined flow tube (a 1180 micron capillary) and the Pd PEPPSI-IPr catalyst; without either, the catalyst or t...
A process has been developed for the deposition of Pd black onto the inner surface of micro-capillaries and these films have been examined by Scanning Electron Microscopy (SEM) and Energy Dispersive X-ray (EDX) analysis to confirm their structure and elemental composition. These films have been shown to be highly catalytically active in metal-catal...
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.