Giuseppina Laganà

• DDS, PhD
• PhD at University of Rome Tor Vergata

Background: The aim of the present cross-sectional study was to assess oral and functional conditions, the prevalence of malocclusions, and oral habits in a population of schoolchildren in Rome (Italy). Methods: The study sample included n. 1033 subjects, between 6 and 14 years of age, attending public schools in Rome. Oral health condition, occlus...

Background Interleukin-6 (IL-6) represents one of the main molecules involved in inflammatory responses, which can be altered in either patients with cognitive impairment or obstructive sleep apnea (OSA). The present study aimed to evaluate serum IL-6 levels and cognitive performance in patients with severe OSA (Apnea-Hypopnea Index - AHI >30/h)....

Background: The aim of the present study was to compare the vertical dimension changes, before and after treatment, in two groups of growing patients, one group treated with clear aligner therapy versus a group treated with Quad-helix and bite-block therapy. Methods: The studied sample was composed of n. 40 patients (20 females and 20 males with a...

Background: this study aims to investigate the accuracy and completeness of ChatGPT in answering questions and solving clinical scenarios of interceptive orthodontics. Materials and Methods: ten specialized orthodontists from ten Italian postgraduate orthodontics schools developed 21 clinical open-ended questions encompassing all of the subspeciali...

Background: Emotional impulsivity has been found to be relevant in explaining the association between sleep problems and depressive symptoms, suggesting the potential role of impulsivity as a key underlying mechanism of this link. The objective of this study was to take a preliminary step in understanding the mediating role of impulsivity in the r...

This study aimed to analyse the effectiveness of four different designs of the Mandibular Advancement Device (MAD) and the morphological changes on upper airway characteristics of Obstructive Sleep Apnea (OSA) patients inducted by each of them, detected by Cone Beam Computer Tomography (CBCT) 3D imaging. Twenty-two patients were recruited after an...

MAD is the gold standard therapy for mild/moderate OSA and is a second-choice treatment in patients with severe OSA not responding to CPAP. The aim of this study was to analyze the upper airway characteristics of OSA patients and the morphological changes in the upper airway, inducted by four different types of mandibular advancement devices, using...

Aim: The upper jaw transverse deficit is certainly one of the most common clinical issues in the orthodontic field. It can be due to skeletal or dental factors, and its etiology may be both genetic and environmental. Rapid maxillary expanders (RMEs) are certainly the most effective appliance for upper transverse deficiency correction. The aim of th...

Background To evaluate the prevalence and the distribution of dental anomalies in an Albanian orthodontic sample. Methods For this retrospective study, a sample of panoramic radiographs (PR) of n. 779 (456 F and 323 M, mean age of 15.1 ± 5.5 years) Albanian subjects with no genetic syndromes or craniofacial malformations (e.g., cleft lip/palate),...

Background: Obstructive sleep apnea syndrome (OSAS) may be associated with and activates the stress response system, and variation in the physiological antioxidant capacity of body fluids. Our aim was to evaluate the variation of pH and antioxidant capacity on the saliva of obstructive sleep apnea subjects (OG) compared to a control group (CG). M...

Abstract Background The aim of the study was to compare the amount of interproximal enamel reduction (IPR) provided on ClinCheck software with the amount of IPR carried out by the orthodontist during treatment with clear aligners. Methods 30 subjects (14 males, 16 females; mean age of 24.53 ± 13.41 years) randomly recruited from the Invisalign acco...

The main cause of mortality in Marfan syndrome (MS) is aortic disease. Obstructive sleep apnea (OSA) is highly prevalent in MS, and it is also associated with cardiovascular risk and maxillary deformities. The aim of this research was to analyze the possible relations between OSA, palatal morphology, and aortic root diameters in growing subjects. A...

Background The aim of this study was to evaluate a possible correlation between sleep bruxism and risk factors of developing obstructive sleep apnea syndrome (OSAS) in a sample of growing subjects and to assess parental awareness about sleep bruxism in their children. Methods: The sample was composed of 310 subjects (173 females and 137 males), wit...

Sleep Disordered Breathing (SDB) comprises a group of diseases characterized by alterations in the frequency and/or depth of breathing during sleep. The aim of this study was to investigate the frequency of SDB in a group of Albanian children and adolescents and to describe its social, physiological, psychological, sleep-related, and anthropometric...

Background: Aim of the study was to evaluate the gelatinolytic activity in the saliva and gingival crevicular fluid from a sample group of subjects with Marfan syndrome. Methods: Two groups were analyzed in this case-control study. A group of 28 subjects with Marfan syndrome (MG) was recruited from the Centre for Rare Disease, Marfan Clinic of T...

Background Marfan’s syndrome (MFS) is a systemic disorder of connective tissue caused by mutations in the extracellular matrix protein fibrillin-1. Orofacial characteristics may be useful in identification of the syndrome. Severe periodontitis is sometimes observed in MFS patients, but no in-depth information has been reported in Italian groups of...

Background Marfan syndrome is a rare autosomal dominant inherited disease of the connective tissue associated with various craniofacial abnormalities. Aim of the present study was to assess the variability of palatal shape in a sample of 31 Marfan patients compared to a control group of no syndromic subjects, in two stages of dentition, by using 3D...

Background: The aim of present study was to test the association between hypodontia and displaced maxillary canine when compared with a control group. Methods: The study group was composed of 336 subjects with a mean age of 10.7 ± 1.2 years, presenting with at least one missing tooth. Exclusion criteria included syndromes, craniofacial malformat...

Objective Marfan patients had an increasing risk of aortic dissection related to the quality of the aortic wall. The aortic size is not a safe indicator to prevent aortic dissection. Other factors need to be consedered such as the morphology of the aortic root, the Valsalva sinus prolapse, genetic and clinical aspects. We analysed the role of a spe...

Objective: To compare morphologic findings in MRI and skeletal divergence of a group of patients with temporomandibular joint disorders (TMD) subdivided into condylar symmetric and asymmetric. Methods: Fifty-nine adults (26.7 years old) with TMD were retrospectively recruited. Condylar height symmetry was evaluated by orthopantomography (Habets’s m...

Objectives. Adolescent patient treated for bilateral impaction of permanent maxillary canines with adjacent lateral incisors roots resorpted. Methods. M.T., 13 years, male, shows a Class II molar relationship with the persistent of both upper deciduous canines and the unerupted successors. Analysis of CBCT confirms the impaction of maxillary canine...

Background The aim of the present study was to evaluate if the different muscular activity correlated to different degrees of facial divergence has an effect on the time needed to extrude a palatally impacted maxillary canine. Material and Methods Twenty-six patients were retrospectively selected, all treated with a specific cantilever appliance t...

Objectives: To assess the morphological shape variations of the palatal vault in Open Bite (OB) growing subjects when compared with a Control Group (CG) by means of Geometric Morphometric Method (GMM). Materials and methods: The OB Group (OBG) consisted of 75 subjects (39 females, 36 males; mean age: 8.5 ± 0.8 years) who were collected retrospec...

di specializzazione in ortognatodonzia 2 Università degli studi di Roma Tor Vergata, Scuola di specializzazione in ortognatodonzia; UNSBC Tirana (Albania) RIASSUNTO OBIETTIVI Scopo del seguente lavoro è quel-lo di fornire all'ortodontista una serie di raccomandazioni e indica-zioni evidence based aggiornate per la diagnosi e il trattamento del russ...

Objective: To evaluate the relationship between the severity degree of OSA (apnea/hypopnea index AHI>1) and palatal area and volume, measured by 3D analysis of digital casts in Marfan children. Methods: Twenty children with a clinical diagnosis of MS were recruited from a tertiary medical center. All the subjects underwent standard nocturnal pol...

Introduction: Marfan’s Syndrome (MS) is a multisystem disorder of the connective tissue. A number of oral manifestations and craniofacial characteristics show a strong correlation with MS. There are no data available in the literature with regard to morphological characteristics of the maxilla in Marfan’s syndrome assessed by 3D morphometric analys...

Objective. The aim of this study was to analyze the prevalence of infraocclusion of deciduous molars and the pattern of associations with other dental anomalies. Methods. Digital panoramic radiographs of 5005 subjects were initially randomly selected from the files of the Department of Orthodontics of the University of Rome “Tor Vergata”. According...

Objective. The purpose of the study was to analyze the association between dento-skeletal malocclusions, ocular motility, and convergence disorders in growing subjects. Materials and methods. 84 subjects (49 males, 35 females) with a mean age of 7.3±1.7 years were enrolled in a screening procedure for celiac disease at the Department of Gastroenter...

Polyunsaturated fatty acids have been reported to play a protective role in a wide range of diseases characterized by an increased metalloproteinases (MMPs) activity. The recent finding that omega-3 and omega-6 fatty acids exert an anti-inflammatory effect in periodontal diseases has stimulated the present study, designed to determine whether such...

Prompt-gamma activation analysis (PGAA) measurements were carried out at the ISIS Spallation Neutron Source on two sets of functional commercial stainless steel orthodontic archwires, aiming at providing insights into the elemental and isotopic composition differences of two nominally equivalent archwires. The results were compared to those obtaine...

Background To analyze the prevalence and associations between dental anomalies detectable on panoramic radiographs in a sample of non-orthodontic growing subjects. Methods For this cross-sectional study, digital panoramic radiographs of 5005 subjects were initially screened from a single radiographic center in Rome. Inclusion criteria were: subject...

Quantitative metallurgical and phase analyses employing neutron diffraction technique were conducted on two as-received commercial rectangular austenitic stainless steel orthodontic archwires, G&H and Azdent, 0.43×0.64 mm (0.017×0.025 inch). Results showed a bi-phase structure containing martensitic phase (45.67% for G&H and 6.62% for Azdent) in ad...

Background: To analyze the prevalence and associations between dental anomalies detectable on panoramic radiographs in a sample of non-orthodontic growing subjects. Methods: For this cross-sectional study, digital panoramic radiographs of 5005 subjects were initially screened from a single radiographic center in Rome. Inclusion criteria were: subje...

Objective: To analyze variations in palatal morphology in subjects presenting unilaterally impacted maxillary permanent central incisors compared with a control group of subjects without eruption anomalies using a three-dimensional (3D) analysis. Materials and methods: Twenty-six white subjects (10 girls and 16 boys; mean age 9.5 ± 1.5 years) wi...

Aim: To analyse the dental effects on digital dental casts in subjects with Class III malocclusion treated with bonded Rapid Maxillary Expansion and Facial Mask (RME/FM). Materials and methods: A study group sample (SG) of 29 subjects (13 females and 16 males) and mean age of 7.4 years (SD 1.2 years) was selected. A bonded RME was placed and act...

Background The aim of this study was to determine the oral health conditions of an adolescent population of Tirana. Methods A cross-sectional epidemiological study was carried out in a sample (n = 1885), aged 16-19, mean age 17.4 (SD = 1.0), attending public schools in Tirana and province; 1200 adolescents were included into the analysis. A clinic...

Objective: To analyze the effects on vertical dentoskeletal dimension produced by cervical headgear (CHG) or Pendulum (P) both followed by full fixed appliances in growing patients with Class II malocclusion. Material and methods: The CHG group (CHGG) consisted of 40 patients (25 females, 15 males) with a mean age of 11.5 years. The P group (PG)...

Aim The aim of this study was to assess the prevalence of oral habits in an Albanian population of schoolchildren. Materials and methods Study design: A sample of 2617 subjects, aged 7-15, was examined by clinical observation without radiograms. The sample comprised 1257 males and 1360 females, with no history of orthodontic treatment. Aestethical...

The aim of this study was to assess the prevalence of oral habits in an Albanian population of schoolchildren. Study design: A sample of 2617 subjects, aged 7-15, was examined by clinical observation without radiograms. The sample comprised 1257 males and 1360 females, with no history of orthodontic treatment. Aestethical frontal and profile analys...

In this study we assessed the influence of rapid maxillary expansion (RME) on the intraosseous vertical position and inclination of the impacted incisors diagnosed at an early developmental stage on panoramic radiographs and subsequently treated by surgical removal of the obstacle. Following surgical removal of the obstacles to incisor eruption (T1...

To provide clinicians with useful information for immediate diagnosis and management of impacted maxillary incisors due to trauma. We present a case of post-traumatic impaction of a central right maxillary incisor in a young patient. The treatment plan consisted in the interceptive management (surgical and orthodontic), the valuation of the necessa...

The purpose of this study was to assess the effectiveness of rapid maxillary expansion (RME) vs simply monitoring the eruption of permanent maxillary incisors following the surgical removal of obstacles to their eruption (supernumerary teeth, odontomas). Following surgical removal of the obstacles to incisor eruption (T1), 62 patients were randomly...

The aim of present study was to determine the prevalence of malocclusions, oral habits and the need for orthodontic treatment in a sample of 7- to 15-year-old Albanese schoolchildren. The final sample comprised 2,617 subjects (1,257 males and 1,360 females), all orthodontically untreated. Occlusal relationship and the functional analysis were recor...

Abstract: Purpose: The purpose of this study was to assess the effectiveness of rapid maxillary expansion (RME) vs simply monitoring the eruption of permanent maxillary incisors following the surgical removal of obstacles to their eruption (supernumerary teeth, odontomas). Methods: Following surgical removal of the obstacles to incisor eruption (T1...

Objective: This prospective study evaluated the density of the midpalatal and transverse sutures as assessed by low-dose CT before rapid maxillary expansion (T0), at the end of active expansion (T1) and after a retention period of 6 months (T2). Methods: The study sample comprised 17 pre-pubertal subjects (mean age 11.2 years) with constricted m...

The aim of this prospective study was to evaluate the effects of rapid maxillary expansion (RME) on the palatal area as assessed by low-dose CT before treatment (T0), at the end of active expansion (T1) and after a retention period of 6 months (T2). The study sample comprised 17 prepubertal subjects (mean age 11.2 years) with constricted maxillary...

When the incisors do not erupt at the expected time, it is crucial for the clinician to determine the etiology and formulate an appropriate treatment plan. THE AIM OF THIS REPORT IS TO PROVIDE USEFUL INFORMATION FOR IMMEDIATE DIAGNOSIS AND MANAGEMENT OF IMPACTED MAXILLARY INCISORS USING THE INTERCEPTIVE TREATMENT: removal of obstacles and rapid max...

Riassunto Obiettivi. Scopo del presente lavoro è fornire al clinico indicazioni utili e di immediato utilizzo per il recupero degli incisivi mascellari in mal-posizione intraossea a causa della presenza di un ostacolo lungo il loro percorso eruttivo. Materiali e metodi. S.P., 8 anni, si è presentato presso il reparto di Ortognatodonzia del Policli-...

Riassunto Obiettivi. Scopo del lavoro è focalizzare l'attenzione sugli odontomi, i tumori odontogeni più comuni e la loro associazione con il ritardo di eruzione degli incisivi permanenti. Materiali e metodi. Attraverso l'analisi della letteratura sono state esaminate le varie teo-rie eziologiche e le diverse classificazioni degli odontomi. Sono st...

The aim of this study was to determine the caries prevalence in urban and suburban Albanian schools. A large sample (n= 2617) of subjects, aged 7-15, was examined by a clinical observation without radiograms. The sample comprised 1257 males and 1360 females. For each subject an anamnestic questionnaire about feeding, fluoride, dentist attendance an...

The aim of this study was to evaluate the changes in the transverse dimension and the perimeter of the maxillary arch produced by low friction self-ligating brackets TIME 3 compared to the Invisalign technique. Both the self-ligating sample and the Invisalign group were composed of 20 subjects, evaluated at the beginning (T0) and at the completion...

Riassunto Obiettivi . Focalizzare l'attenzione sull'iperdon-zia, una tra le più frequenti anomalie dentali di numero, e sull'associazione tra questa e il ritar-do di eruzione degli incisivi permanenti. Materiali e metodi . Attraverso l'analisi della letteratura sono state esaminate le varie teorie eziologiche, le diverse classifi cazioni dei den-ti...

The aim of this study was to analyse skeletal, dental and arch morphology in a group of subjects with dental agenesis and to compare it with a control group. 2 groups of subjects were selected: an experimental group (84 patients) with tooth agenesis and a control group (84 subjects) without tooth agenesis. Skeletal, dental, morphological and aesthe...

Self-ligating versus Invisalign: analysis of dento-alveolar effects. Aim. The aim of this study was to evaluate the changes in the transverse dimension and the perimeter of the maxillary arch produced by low friction self-ligating brackets TIME 3 compared to the Invisalign technique. Materials and methods. Both the self-ligating sample and the Invi...

Aim of this report is to describe a case of a patient in mixed dentition with dento-skeletal class II malocclusion, deep bite, increased overjet and gummy smile.IN THIS KIND OF CLINICAL CASE THE OBJECTIVES OF TREATMENT WERE: to correct the dento-skeletal malocclusion, to obtain a correct overbite and overjet, to control the permanent teeth in a goo...

ObjectivesThe aim of the present study was to use published data to evaluate quantitavely the skeletal and dental effects of extraoral and intraoral molar-distalizing appliances in individuals with Class II malocclusion.Materials and methodsWe conducted a literature search that identified 37 prospective or retrospective clinical studies that met ou...

Aim of this study was to analyse the relationship between arch form and craniofacial morphology in a group of 715 subjects in mixed dentition, mean age 8 years and 8 months, orthodontically treated at the Dental Clinic of Tor Vergata University in Rome. Data deriving from study models and cephalometric tracings were studied by statistical analysis...

Sleep apnoea obstructive syndrome (OSAS) is a disease frequently seen by both general practitioners and specialists. In their study the Authors analyse clinical characteristics, prevalence, snoring, obesity, therapy and complications of OSAS syndrome with particular reference to growing and adult patients.

The aim of the present report is to describe a case of a patient with eruption disturbances of an ankylosed lower primary second molar, delayed development of a maxillary permanent canine associated with an odontoma and a class III dental malocclusion. In such a case the objectives of treatment are: to prevent impaction of the lower second premolar...

This report describes a rare case of a supplemental tooth with a morphology similar to a lateral incisor, found in the canine region of the mandible of a 6-year-old male. The purpose of this paper is to report the importance of early diagnosis and treatment during mixed dentition. The treatment was extraction of the primary mandibular left canine s...