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Giuseppe R. Brera

Giuseppe R. Brera
Universita Ambrosiana

MD, Professor LD MA

About

91
Publications
20,426
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191
Citations
Introduction
I'm introducing and spreading an epochal paradigm revolution of medical science (1995-1996)," the Person Centered Medicine Paradigm", (1999) - and "the Person Centered Health Paradigm", (2005) . To date Medicine is passed from a mechanistic and deterministic paradigm , only bio-technological and reductionist for the human nature knowledge , to an undeterministic person centered one wich calls for a rigorous re-assessing of clinical method , research and medical education.
Additional affiliations
January 2002 - present
Position
  • Director of the Person Centered Medicine Research Center
Description
  • Person Centered Medicine-Medical Education-Clinics
June 1998 - October 2016
Ambrosiana University
Position
  • Education in Person Centered Medicine
Description
  • Medical Education
January 1991 - present
Position
  • Managing Director
Description
  • Person Centered Medicine Theory -Teaching - Reserch Epistemology and Medicine
Education
October 1966 - July 1972
State University
Field of study

Publications

Publications (91)
Article
Hospital solidarity is born, develops and ends in love, or at least that is how it should be. It is a strange love, the one that brings Hospitals to life, perhaps paradoxical and anachronistic if one wants to generalise in a rather superficial way, because it finds its object and subject in pain and suffering. It seems illogical that Hospitals can...
Article
In medical science today, much attention is paid not only to what can be experimental, reproducible, observable or describable in data, but also to what concerns the subjectivity of the physician and the patient. We thus break away from a positivistic conception that does little to illuminate our path in this order of phenomena to enter with an obs...
Chapter
Full-text available
.The SARS-COV 2 allostasis theory and the COVID-19 mechanistic primary prevention failure resulted from epistemological ignorance and a guilty omission of secondary prevention. Bacteria, viruses, neoplastic cells, and physical agents constantly challenge the person’s resources to cope with and react. In any pandemic, the first PCM-induced axiomati...
Book
Full-text available
The educational training in pedagogical, psychological, medical work with adolescents is still today fragmented into theories that separate in an epistemologically wrong way the spirit (the natural question of meaning of life) the emotional and cognitive symbolic world and biological variables, three dimensions in continuous interaction and that th...
Conference Paper
Full-text available
The educational training in pedagogical, psychological, medical work with adolescents is still today fragmented into theories that separate in an epistemologically wrong way the spirit (the natural question of meaning of life) the emotional and cognitive symbolic world and biological variables, three dimensions in continuous interaction and that th...
Data
The Ambrosiana University contribution to the paradigm change of health, Medicine, and Medical Education from 1999 “ PERSON-CENTERED MEDICINE”
Preprint
Full-text available
Person-centered Medicine is the paradigm shift of Medicine, medical science, and medical education, based on the interactionist revolution of the basic sciences, determining the relativity of biological reactions to the person and the teleonomy of human nature. The paradigm was theorized with the publication of the Manifesto of Person- centered Med...
Preprint
Full-text available
The problem of the genotoxicity of mRNA and vectorial vaccines against COVID-19, their waning in a short time and immunosenescence of people at high risk ( oldest people with comorbidities) induced the high rate of adverse effects and mortality, and the lack of correspondence between VOC (Variants of Concern) and the mRNA in the market creates grea...
Data
Posology and antiviral targets of the anti SARS-COV 2 pleiotropic therapy
Data
Antiviral targets of the anti-SARSCOV 2 pleiotropic therapy
Preprint
Full-text available
The continued production of variants of SARS-COV 2 due to the change of the Spike Proteins Receptor Binding Motif caused by the characteristics of the virus and the mass vaccination in epidemic time that promotes the immune evasion of the virus, leads to a delay in the production of vaccines after infections and clinical syndromes, which cannot pre...
Preprint
Full-text available
The SARS-COV 2 epidemic has been addressed worldwide with a fundamental epistemological error based on the erroneous deterministic and mechanistic paradigm of medical science and not on the current interactionist-multifactorial-teleonomic Person-Centered Medicine one, which values the subjective-metabolic-immune-environmental resources of the perso...
Book
Full-text available
. In the first part of the treatise, "The virus entry" the author had demonstrated how the SARS-COV 2 virus enters cells through pathological cell membranes characterized by lipid degeneration, thus explaining the vulnerability of the elderly with comorbidities that have atherosclerosis and protection against infection in young people as their comm...
Conference Paper
Full-text available
1. Syndemic identity of COVID-19 pandemic: the experimental child" 2. Limits of the available anti COVID-19 vaccines 3. Genotoxicity of anti-COVID-19 vaccines
Preprint
Full-text available
Micro-RNAs (miR) are non-coding RNA filaments that control mRNA transcription. Micro-RNAs have been studied in cancer pathogenesis, metastasization, cancer therapy, the structuring of the central nervous system, diabetes, and heart disease. Mir-134-138 regulate the development of dendritic spines needed for synapses. Their silencing can lead to aut...
Preprint
Full-text available
SARS-COV 2, like HIV, induces an NK, CD4+, CD8+-based immune-depression proportional to the COVID-19 severity and immune-anergy after the seventh day from the beginning of clinical symptoms, which is the principal cause of fatalities in older people affected by atherosclerosis-based comorbidities. Since the 2003 SARS-COV pandemic, this clinical evi...
Chapter
Full-text available
SARS-COV 2, like HIV, induces an NK, CD4+, CD8+-based immune-depression proportional to the COVID-19 severity and immune-anergy after the seventh day from the beginning of clinical symptoms, which is the principal cause of fatalities in older people affected by atherosclerosis-based comorbidities. Since the 2003 SARS-COV pandemic, this clinical evi...
Book
Full-text available
The Ambrosiana University has edited a treatise on SARS-COV 2 by Professor Giuseppe R.Brera, director of the Milan School of Medicine and President of the International Committee for the change of the paradigm of health and medicine. The treatise introduces into virology the revolutionary physiological concept of "Allostasis", hitherto unknown to m...
Conference Paper
Person-Centered Medicine is the first extrinsic paradigm of medical science instituted owing to the last forty years of biomedical science and human sciences advance. Their epistemological bases are interactionism and the human nature teleonomy allowing the freedom and dignity-based "being-person" identity. The Medicine indeterministic epochal shif...
Presentation
Full-text available
Person-Centered Medicine is the first extrinsic paradigm of medical science instituted owing to the last forty years of biomedical science and human sciences advance. Their epistemological bases are interactionism and the human nature teleonomy allowing the freedom and dignity-based "being-person" identity. The Medicine indeterministic epochal shif...
Book
Full-text available
PRESENTATION This second book on Person-Centered Medicine (PCM), written by the theory author- the first was published in 2001 by the same author- introduces the PCM paradigm applied in the Milan School of Medicine since 1998, and the first results of the Person-Centered Clinical Method application in clinical practice. The book is essential to un...
Presentation
Full-text available
The mystery of the SARS-COV 2 entry in cells , allostasis and the COVID-19 severity up to fatality has been revealed. The theory, inspired by the Person-Centered Medicine paradigm change of medical science and medicine and the derived health concept relativity, resulted from the prof. Giuseppe R.Brera’s (University Ambrosiana-Milan School of Medic...
Article
Full-text available
The “Mercury Syndrome” or the smartphone addiction Giuseppe R. Brera Summary Different investigation scales like SAS ( Smartphone addiction scale), SAPS (Smartphone Addiction Proneness Scale), e la KS-scale. (The Korean self-reporting internet addiction short-form scale ), gives evidence to the existence of a mass of adolescents and young people...
Article
Full-text available
« Persona est Individua substantia rationalis naturae ». This definition, that filled the Middle Age philosophy, makes relative the person ontology to his/her acts and functions and it is wrong, because also persons without intelligence, at the first or final stage of their life, or unable of a human relation like schizophrenics or suffering from a...
Book
Full-text available
he Human nature has a relative value in agreement with hermeneutics which interprets it . The interpretative theory consequently is at the origin of the epistemology , its objects and methods of knowing reality. Therefore the progress of science and humanity is entrusted to hermeneutics of the human symbolic world. In the study of Adolescence, the...
Preprint
Full-text available
The identification of two new clinical syndrome: “The Post Hexavalent Vaccination Sudden Infant Death Syndrome ”, (PHVSIDS) and the Post Vaccination ASIA Syndrome (PVAS), irrefutably confirmed by the scientific literature and for PHVSIDS from autopsies of newborns died without pathologies inducing a life risk, calls for an urgent revision of the cr...
Experiment Findings
Full-text available
This is a descriptive pilot study. 20 Physicians (7 medical practitioners, 6 Paediatricians, 3 hospital doctors, 4 private doctors) accepted to fill out a questionnaire on “ PCCM Quality in Medical Practice” and e-mail it upon completion. Questionnaire items, positive answer rates on the perception of change in medical practice, associations with t...
Article
Full-text available
THE HEXAVALENT VACCINATION RUSSIAN ROULETTE THE HEXAVALENT VACCINATION RISK FOR CHILDREN AND ADULTS' LIFE . THE INTRODUCTION OF THE POST HEXAVALENT VACCINATION SUDDEN DEATH SYNDROME (PHVSIDS) AND THE POST VACCINATION ASIA SYNDROME( PVAS). REVIEW UNDER THE PATRONAGE OF THE ITALIAN SOCIETY OF ADOLESCENTOLOGY AND ADOLESCENCE MEDICINE, THE MILAN SCHO...
Book
Full-text available
Proceedings of the Conference : Medical science and health paradigm change 13-14-15 October 2017.Milan,Italy
Data
The epistemological principles of Person Centered Medicine (published in 1999)
Presentation
Full-text available
In the last forty years there has been a great change of medical science through the progress of neurobiology, the birth of quantum biology, the development of epigenetics, the change of physiology with the concept of “Allostasis instead of “Homeostasis”, the opening of new interactionist investigation fields like Psycho-neuro-endocrine-immunology...
Presentation
Full-text available
The paper introduces a new research paradigm against malaria
Presentation
Full-text available
A new paradigm for research against Malaria from the Antimalaria Project of the Milan School of Medicine
Article
Full-text available
Socrates…… Well then, could we ever know what an art makes the man himself better, if we were ignorant of what we are ourselves ? Alcibiades: Impossible ! (Plato) Medical science is changed because of the epistemological revolution of basic sciences in the last 40 years through the birth of Epigenetics, Allostasis, Psycho-Neuro-Endocrine-Immunology...
Article
Full-text available
Medical Education in Person Centered Medicine in Italy and its international development * Giuseppe R.Brera** SUMMARY*** Person Centered Medicine (PCM) is the foundation of the first paradigm of Medicine and Medical Science, enunciated in 1999 in the “ Person Centered Medicine Epistemological Manifesto”, an epistemological change from the domina...
Research
Full-text available
The contribution is a partial summary of the prof Brera’s invited presentation at World Health Organization in the IVth Geneva Conference in Medical Education Proceedings in the Symposium: Person Centered Medicine and Medical Education - May 4 2011, , pg 39-41
Research
Full-text available
The epistemological revolution of basic sciences which irrefutably documented the interaction subjectivity-biology-environment,determined a shift from the dominant intrinsic deterministic mechanic bio-technological paradigm toward a person centered indeterministic one. Its introduction in clinics and research is necessary to prevent epistemological...
Research
Full-text available
Key words Kew words In vitro fertilization, mental retardation, autistic disorder, pulmonary embolism, ovarian cancer - The bio-technology of fertility is very spread all over the world, but it is only a bio-technical tool that cannot produce lost of the medicine objective ethics and that cannot make individuals’ health or life relative to subject...
Research
Full-text available
Reliability and validity of Person Centered Medicine Clinical method from the analysis of Physicians 144 Clinical Reports prepared to apply Person Centered Medicine
Research
Full-text available
Results of the application of Person Centered Clinical Method in Clinical Practice
Conference Paper
Full-text available
Adolescence is the life period where persons discovery that existence experience time is a mystery which calls to be interpreted-giving a meaning to it-according to a necessary code for survival and life: truth, love and beauty, that adolescents live as personal resources, which make each time as opportune –kairos-for a personal realization as dign...
Data
The model introduces the Person Centered Reality Theory according Kairology.The model is interactionist ( spirit-mind bod) and teleonomic. The person, thank to genetic structures receive possibility to interpret possibilities offered by experience constructing reality or pseudoreality. The concept of reality is consistent with the concept of health...
Conference Paper
Director of the Milan School of Medicine and Person Centered Medicine International Academy SUMMARY Up to now, to our knowledge, medicine and medical science didn't ever submit to a scientific investigation clinical method. A reliable, valid, teachable clinical method is the basis of the Medicine progress and public health, because it is the cond...
Conference Paper
Full-text available
Person Centered Medicine and Change of the Paradigm in Medical Education Giuseppe R. Brera MD ,MA. MAG.LD* 1 Person Centered Medicine is the first paradigm of Medicine and Medical Science, enunciated in 1999 in the “ Person Centered Medicine Epistemological Manifesto” a change from the dominant intrinsic bio-molecular one. 2 The paradigm kew wor...
Presentation
Full-text available
1 Person-Centered Medicine is the first paradigm of Medicine and Medical Science, enunciated in 1999 in the " Person-Centered Medicine Epistemological Manifesto" a change from the dominant intrinsic bio-molecular one. 2 The paradigm kew words are: Being person", Teleonomy, Objective ethics, Interactionism, Indeterminism". The paradigm change event...
Article
Full-text available
Person Centered Medicine (PCM) is a new inter-actionist, indeterministic, extrinsic Paradigm of Medicine, born in 1999, based on the Theory of the determinate and the quality indeterminate relativity of biological reactions” (1996). Structuring a new health epistemological model, developed from Medical Science base interactionist investigations, co...
Article
Full-text available
The recent advances in the psychoneuroendocrinology have suggested the possibility to modulate tumor hormone dependency through a neuroendocrine approach. In particular, it has been proven that the pineal neurohormone melatonin (MLT) may stimulate estrogen receptor (ER) expression in breast cancer cells and inhibit the aromatase activity. On this b...
Article
Full-text available
Abbreviations: Melatonin (MLT), complete response (CR), partial response (PR), stable disease (SD), disease control (DC), progressive disease (PD), T helper lymphocytes (TH, CD4 +), T regulatory lymphocytes (T reg, CD4 + CD25 +) Summary Background: The recent advances in understanding the immunobiological interactions responsible for cancer progres...
Article
Full-text available
Lymphocytopenia represents one of the most evident side-effects of radiotherapy (RT), particularly in the case of irradiation of pelvis, since it is the main location of bone-marrow proliferating cells in adults. Because of the fundamental role of lymphocytes in suppressing anticancer immunity, RT-induced lymphocytopenia could negatively influence...
Article
Full-text available
Cancer progression depend on the immune and endocrine status of the patients. In particular, it has been observed that abnormally high levels of cortisol and/or an altered circadian secretion are associated with a poor prognosis in advanced cancer patients. The present study was performed to establish whether cancer-induced hypercortisolemia depend...
Conference Paper
Full-text available
In medical science, there is a need to shift from a mechanistic paradigm, to an explicit, person-centred, indeterministic, interactionist one. This change is supported by psycho-neuro-endocrine immune and neurobiological investigations which show a qualitative relation among human subjectivity and behaviour, possibilities and quality of coping. and...
Article
Full-text available
The recent advances in the investigation of tumor immunobiology have suggested that cancer chemotherapy, in addition to its well known cytotoxic activity, may play modulatory effects on the endogenous production of cytokines involved in the control of both tumor angiogenesis and antitumor immunity. Cancer chemotherapy constantly acts with inhibitor...
Article
Full-text available
The present study was carried out to evaluate the influence of a short-period IL-2 administration on the efficacy of chemotherapy in metastatic colorectal cancer patients with pretreatment lymphocytopenia, which was defined as a lymphocyte count of less than 1500/mm3. The study included 144 consecutive metastatic colorectal cancer patients, who und...
Conference Paper
Full-text available
Epistemology is the mother of science and vice versa. Medical science, from Claude Bernard, entrusted theories’ corroborations to experimental laboratory and clinical investigations. This approach lead to the “Evidence Based Medicine” theory (EBM) which links clinical reasoning to scientific results of clinical trials and underrates the traditional...
Data
Data from Lombardia Region, Italy, about clinical outcomes of a student in Person Centered Medicine Clinical Method
Book
Summary of the book “La medicina centrata sulla persona e la Formazione dei medici nel terzo Millennio” IEPI Pisa 2001. ISBN 88-8147-245-7 Person Centered Medicine is the change of Paradigm of Medicine and Medical Science born in Italy in 1998 and officially instituted in Postgraduate Courses of the University Ambrosiana of Milan with quality proc...
Book
Full-text available
The first and unique Book-to date- in Person Centered Medicine (pg 153) which introduced in Medical Science and Clinics Person Centered Medicine, the Paradigm Change in Medical Science, the Person Centered Clinical Method, Medical Education in Person Centered Medicine, the Person Centered Medicine clinical sheet It is the result of the application...
Article
Full-text available
The core of adolescence is the appearance of new possibilities in perceiving and constructing reality in personal and interpersonal relationships. The whole person, body, mind, and spirit is involved in what could be defined as a new subjective hermeneutics. Possibilities originate from new logical, noethical, biological, affective, and social comp...
Book
Full-text available
THE EPISTEMOLOGICA MANIFESTO OF PERSON-CENTERED MEDICINE *Giuseppe Rodolfo Brera 1Abstract“Person -centred medicine” represents a new epistemologic orientation for medical science. The components of the paradigm derive firstly from an acknowledgement of the impact of Christianity on the History of medicine, secondly from kairological introspectio...
Article
Full-text available
Person - centred medicine” represents a new epistemologic orientation for medical science. The components of the paradigm derive firstly from an acknowledgement of the impact of Christianity on the History of medicine, secondly from kairological introspection, which, starting from phenomenological and anthropo-analytical premises, provides evidence...
Article
Dignity has not generally been seen as something that can be applied to clinical medicine. There are instances, however, where this has direct application. An adolescent with phobic problems and “at risk” behaviors who seemed not to change with a normal psychodynamic approach, quickly solved his problems when his counselor utilized a method that in...
Article
Full-text available
Abstract Studies on the interactions between the central nervous, immunitary and endocrinological systems, the mind and behaviour, permit a theory of medical science to be formulated . The variability of immunitary reactions to the experimental possibility offered to animals to escape - or otherwise - conditions of stress determined the obsolescenc...
Article
The Human nature has a relative value in agreement with hermeneutics which interprets it . The interpretative theory consequently is at the origin of the epistemology , its objects and methods of knowing reality. Therefore the progress of science and humanity is entrusted to hermeneutics of the human symbolic world. In the study of Adolescence, th...
Book
Summary of the book A Revolution for the Clinical Method and Biomedical Research : the Determinate and the Quality Indeterminate Relativity of Biological Reaction Giuseppe R.Brera ©Copyright Università Ambrosiana 1996 The book introduces the concept of "Relativity of Biological Reactions" separating these from "Biological constants" necessary fo...
Article
The scientific logos of Medicine, founded on the clinic method and biomedical research, permits us to discover the determinant role of subjectivity, that is the subject's psychological-existential dimension in edifying, on the basis of natural laws, the human, individual and interpersonal reality. The close inter-connections between immunitary, en...
Article
Giuseppe R. Brera's B-test was used in a group of students from upper secondary school (102 male adolescents and 86 females) in order to carry out a preliminary standardisation in centiles and to assess the pattern of the seven scales of the test: mood, anxiety, interpersonal affectivity, sociability, autonomy of ego, strength of ego and guilt in a...
Article
Full-text available
Article
PIP: The English language and Scandinavian literatuare include an ample discussion of the problem of negative psychological and psychiatric sequelae of abortion. However, most works are based on an epistemologically incorrect methodology, being limited to a statistical comparison of the absence and presence of sequelae. The present study is based o...

Questions

Questions (52)
Question
Assisi 2024
PERSON-CENTERED HEALTH
and THE RESILENT ADOLESCENT
ASSISI 25-26-27 October 2024
Pre-Conference presentation of the Congress Assisi 2024
Milan, 1 June 2024
THE INDUCTION OF RESILIENCE THAT INVOLVES ALL DIMENSIONS OF THE PERSON, SPIRIT-MIND AND BODY, WHICH CANNOT BE FRAGMENTED, IS THE GREAT CHALLENGE OF HEALTH SYSTEMS AND INDIVIDUALS, WHO ARE STILL MORE ORIENTED TO BE PROBLEM-CENTERED, BECAUSE THEY ARE SUBJECTED TO PRESSURE FOR PROFIT. TO DATE, WE HAVE AN EFFECTIVE CLINICAL METHOD AND PERSON-CENTERED HEALTH PROGRAMS FOR INDUCING RESILIENCE AND RESEARCH METHODS THAT ASK TO BE APPLIED AND SHARED. THE AIM OF THE CONGRESS IS TO PROMOTE THE PRESENTATION AND SHARING OF THEORIES, RESEARCH, METHODS, CLINICAL CASES FOCUSED ON THE RESILIENCE OF ADOLESCENTS AND YOUNG PEOPLE IN DIFFERENT SOCIAL AND CULTURAL CONTEXTS WITH A MULTIDISCIPLINARY AND INTEGRABLE APPROACH according the person-centered health paradigm:
" THE BEST POSSIBILITIES FOR BEING THE BEST HUMAN PERSON"
ASSISI, WHERE THE WFSA, SIAD, AND THE AMBROSIANA UNIVERSITY HAVE PROMOTED 11 INTERNATIONAL CONGRESSES AND WHERE IN 1993 THE ADOLESCENTOLOGY THEORY , KAIROLOGY AND THE UNIVERSAL DECLARATION OF YOUTH RIGHTS AND DUTIES WERE PRESENTED TO THE WORLD, IS AN IDEAL CITY TO HOST THIS MILESTONE CONGRESS.
THEORETICAL , AND EXPERIMENTAL PRESENTATIONS, CLINICAL REPORTS, PROGRAMS AND METHODS, SYMPOSIA ARE WELCOME
WELCOME IN ITALY AND IN ASSISI FOR THIS UNFORGETTABLE CONFERENCE
MAIN TOPICS
Person-centered health theory and resilience in young people Spirituality, religious faith and resilience Family and resilience Education in Youth Health Rights Person-centered medicine and young people Health Education to resilience Learning programs to resilience in schools Counseling with the adolescent and young people Psichotherapy with the adolescent Medical Education and resilience Special topic
A threat to humanity: the smartphone addiction. Philosophy,Social Psychiatry,Psycho-Neurobiology Abstracts on
Artificial intelligence Mental health, adolescence and resilience in particular social and cultural contexts as war, immigration. Health psychoanalysis and the promotion of the genital personality Psychoneurobiology, epigenetics and resilience Mental health and resilience to drugs Epidemiological theory and resilience
are welcome
LE ROY TRAVIS
WFSA INTERNATIONAL PRIZE
FOR THE BEST PRESENTATION
by INVESTIGATORS UNDER 35
Workshops
Person-Centered Health Program (Kairos program) Resilience and research methods Medical education in Person-Centered Clinical Method
Invitation to attend the
The chairs: Giuseppe R.Brera , Claudio Violato, Richard Fiordo
Conference website
Question
"La Charte Mondiale de la Santé-The World Health Charter was presented in 2017 at the International Congress for the paradigm shift of medical science.
I am pleased to invite Research Gate scientists
to sign it before its sending to the United Nations
Giuseppe R.Brera
President
Inyternational Committee for the World Health Charter
Attached
Text
Signature form
Question
The current paradigm of Medicine and the health concept urgently requests a qualitative shift in light of the epistemological change of medical science. To date, medicine is applied and taught with a wrong mechanistic and deterministic approach that the progress of basic science has overcome by revealing the interaction between subjective- biological-environmental variables and the teleonomy of human nature. To date, this epistemology is necessary for the right approach to the patient, which cannot be only reduced to a bio-technological approach, confounding tools with the person-centered clinical work, which can be avoided by teaching the Person-centered clinical method, the result of the epistemological revolution of medical science.
Person-centered medicine teaching, interactionism, and teleonomy must be introduced in all Medical schools that to date risk being closed only in a bio-technological paradigm, when to date, empathy, person-diagnosis, and the interactionist multidimensional resource-centered clinical method since 1999 taught at the Milan School of Medicine of Ambrosiana University, allow saving suffering, drugs, and hospital admissions.
In order to accelerate the Medicine paradigm shift, the Milan School of Medicine of Ambrosiana University and the World Health Committee, under the patronage of the European Parliament, and the Pontifical Academy of Science promoted two world Congresses in streaming
THE PARADIGM CHANGE OF MEDICINE: THE EPISTEMOLOGICAL AND SCIENTIFIC BASIS OF PERSON-CENTERED MEDICINE
21-22 June 2023
PERSON-CENTERED MEDICINE: THE PARADIGM CHANGE IN MEDICAL SCIENCE AND MEDICAL EDUCATION
23 June 2023
The two Congresses, after those of 2017 and 2021, further confirmed the change of paradigm of Medicine introduced by Ambrosiana University in 1999. (www.healthparadigmchange.it)
Currently there is an urgent need for an adaptation of medical education to the Person-Centered Medicine paradigm and the Persn-centered clinical method
The Milan Medical School of Ambrosiana University, which first introduced in 1999 the new paradigm that changed also in 2011 the current concept of health , since 2003 has promoted in Italy a master’s degree in Person-Centered Medicine and since 2009 an international program and a PHD (www.unambro.it), of which the Summer School is part.
In 2023 the Summer School is held from 4 to 9 September 2023 in the beautiful Viareggio, ( Italy-Toscana) "The pearl of the Tyrrhenian Sea", with the collaboration of the province of Lucca.
Today there is an urgent need for clinical teachers able to teach the true , not false medicine.
The proceedings of the Concresses can be requested to dipedit@unambro.it ( without any charge).
Question
After the revolutionary indeterminist and teleonomic change of Medicine occurred thanks to the person-centered shift of basic sciences, in physiology, psychoendocrinoneuroimmunology , psychophysiology, neurobiology, synthesized by the birth in 1999 of the Person-centered Medicine paradigm , the curriculum of the Doctors must be changed.
The paradigm shift of medical education will be formally established in Congress
PERSON-CENTERED MEDICINE : THE PARADIGM CHANGE IN MEDICAL SCIENCE AND MEDICAL EDUCATION
with the patronage of the Pontifical Academy of Sciences, at the Pontifical Academy of Sciences (Holy See-Vatican State) on 24 June 2023.
The Conference is particularly dedicated to the principals of the School of Medicine and the world leaders of Medical Education and the International Health and Medical Organizations
Participation in the Conference is only possible with institutional accreditation.
We also inform that the World Congress in streaming (open to all investigators and clinicians also as individuals) has been postponed to 21-22-23 June
THE CHANGING PARADIGM OF MEDICINE: THE EPISTEMOLOGICAL AND SCIENTIFIC BASIS OF PERSON-CENTRED MEDICINE
Information about both conferences can be found on the University’s websites: www.unambro.it and www.healthparadigmchange.it (registration forms and abstracts)
we hope in your presence
Giuseppe R.Brera
Question
On 21-22-23 June 2023, the Milan Medical School of Ambrosiana University promoted an International Conference in streaming, on the subject:
The paradigm change of medicine: the epistemological and scientific basis
of Person-Centered Medicine
This conference is aimed to underscore the urgent need for overcoming Medicine's current wrong and obsolete deterministic-mechanistic-biological paradigm based on the linear causality toward the assumption in Medical Education, Clinics, and Public Health of the right indeterministic person-centered paradigm of human nature, Medicine, medical science, and health.
Call for papers on the following topics:
EPISTEMOLOGY AND MEDICINE, ALLOSTASIS PHYSIOLOGY, EPIGENETICS PSYCHO-NEURO-ENDOCRINE-IMMUNOLOGY, PSYCHOPHYSIOLOGY, NEUROBIOLOGY, MEDICAL ETHICS, PERSON-CENTERED MEDICINE, PERSON-CENTERED HEALTH, PERSON-CENTERED PSYCHIATRY, MEDICAL EDUCATION, WHO and HEALTH DEFINITION, SOCIAL PSYCHIATRY
If you have an interactionist approach to behavior and affectivity quality, PNEI, neuromodulation, and epigenetics you are welcome.
Deadline: June 10, 2023
Registration and abstract forms on
Giuseppe R.Brera
Rector of Ambrosiana University
Director of the Milan School of Medicine
Question
There is scientific evidence of mRNA and vectorial vaccines' genotoxicity.
mRNA vaccines induce immunodepression increasing vulnerability to communicable and non-communicable diseases ( cancer) and have a high rate of serious adverse effects, including death. Many otherwise healthy young people have died
Scientific evidence is supported by epidemiological data that show an increase in the infection risk from VOC in vaccinated people and in oncologic patients.
Moreover, I suggest reading Christine Cotton's expertise about the mRNA vaccines' unreliability.
In Florida, there was an 83% increase in mortality in vaccinated people.
We proposed on Research gate an International Research Manifesto for the withdrawal of mRNA and vectorial vaccines. if you agree you could sign it for building an international pressure lobby and there is an open discussion on Researchgate about this topic.
Reference on Research Gate
Question
The COVID-19 pandemic finds its basis in the epistemological error imperant in medicine and public health: To date, the obsolete and wrong deterministic-mechanistic paradigm used to cope with the pandemic implementing only biotechnology and profit is "Pathogen-infection- mortality risk" and not the right indeterministic multidimensional one:" Pathogen-anti-pathogen allostasis = antiviral metabolic allostasis and immunity stimulation -resilience- recovery." the basis of Person-Centered Medicine that states that health is: " The choice of the best possibilities for being the best human person." Truth, freedom, and health are inseparable.
( Brera, G.R. Person-Centered Medicine and Person Centered Clinical Method. Milano: Università Ambrosiana ed.: 2021 ISBN: 9798726465432)
The error led to the omission of secondary prevention, which should have been based on research on the first 2002 SARS-COV and 2009 MERS disappeared without mass vaccination.
The error leads to the omission of secondary prevention in the oldest people at risk with comorbidities (93% of deaths).
Genotoxicity due to the silencing of mi-RNA to promoter genes by mRNA vaccines but to date has not yet been investigated in their epidemiological consequences. There is evidence of risk of mortality, cardiovascular and oncological morbidity after vaccination, and a high-risk index for adverse effects, including increased vulnerability to cancer, autoimmune diseases, and cardiovascular diseases. These data call for the immediate withdrawal of mRNA sera worldwide.
Immunodepression induced by multiple injections of mRNA vaccines has been demonstrated. In fact, after two doses, the unvaccinated are more protected from infection than the unvaccinated.
Moreover, there are no" large differences in the median duration of viral shedding among participants who were unvaccinated, those who were vaccinated but not boosted, and those who were vaccinated and boosted." Duration of Shedding of Culturable Virus in SARS-CoV-2 Omicron...
These observations, along with the AB mRNA vaccines waning and the lack or weak presence of IGA in mucosae of upper respiratory ways, make the persecution made by some countries against prudent unvaccinated health professionals a delusion of illiterate governments that prescribed an obligement to vaccination.
Vectorial sera have a great probability of hybridizing human DNA and present risk of autoimmunity and induced cardiovascular pathologies up to death like mRNA.
There are other forms of prevention and easy treatment of COVID-19 in the early stages that make them useless. The state of Florida (USA), having found a risk of 2.3 for mortality in subjects vaccinated by mRNA sera with an 83% increase in mortality under 39 years, has prohibited them. Swede, Denmark, and Canada, respectively. didn't recommend vaccination under 19-50-60 yo. The induction of children and young people's vaccination is a crime against humanity motivated only by profit and power, as the Nobel prize Luc Montagnier agreed.
The 2002 SARS-VOC epidemics and the 2010 MERS have disappeared without mass vaccinations in a year. Mass vaccinations, in addition, in times of epidemic, select increasingly dangerous variants for the evasion of the immune system, an enormous business for BIG PHARMA.
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This letter is intended to propose to Research Gate researchers a World Manifesto for the withdrawal of mRNA vaccines from the market as follows.:
"Researchers of the Research Gate, by highlighting the danger of mass vaccination and boosting with mRNA and vectorial sera for the world health people, make an appeal to governments for their withdrawal from the market and the withdrawal by governments of vaccination obligations. RG researchers, moreover, make an appeal to suspend any crazy suspension from the work of unvaccinated health professionals because of the lack of any scientific motivation and the result of governments' illiteracy which led to a violation of human rights."
Adherence to the World Manifesto takes place through adherence to this initiative in the discussion and mail to
, subscribing to the site and supporting this initiative if you agree.
Giuseppe R. Brera
President of the World Health Committee
President of the Italian National Health Committee
Director of the Milan School of Medicine
Question
The World Health Committee (WHC) is born in 2021 to spread the Person-Centered Medicine (PCM) and Health paradigm, the Medicine indeterministic-teleonomic epistemological revolution born in 1998-1999 at the Milan School of Medicine of Milan that substitutes the current wrong mechanistic deterministic one based on linear causality outside emergence. This epistemological error has been the basis of the SARS-COV 2 pandemic and millions of deads.
WHC, which also recovers the ethical values of the Hippocratic Medicine, is organized in national committees and wants introduce in Schools of Medicine, General Medicine, and in specialties, clinical research PCM overcoming the fragmentation of the person by introducing interactionism and teleonomy.
The Person-Centered Medicine Manifesto and the World Health Charter are the Ethical-epistemological basis of WHC.
A letter of adhesion to the WHC Presidency (Giuseppe R.Brera-Italy) and General Secretariat (Roy Kallivayalil-India) with the proposal of a country delegation or adhesion to an existent one ( see on www.worldhealthcommitteee.net)
An extensive essay on Person-Centered Medicine and Person-Centered Clinical Method, with research results on its application in clinics, is treated in the book
“ Person-Centered Medicine and Person-Centered Clinical Method. Clinical Results of the Medicine Unitary Paradigm teaching and the SARS-COV 2 entry relativity inducing COVID-19 Person-Centered prevention
( Giuseppe R.Brera, Milan, University Ambrosiana ed,2021- distributed by Amazon)
Question
MicroRNAs (miR) are non-coding RNA filaments that control mRNA transcription. MiR has been studied in cancer pathogenesis, metastasization, cancer therapy, the structuring of the central nervous system, diabetes, and heart disease. Mir-134-138 regulate the development of dendritic spines needed for synapses. Their alteration and/or silencing can lead to autistic spectrum disorders and mental retardation and damage to brains in evolution such as childhood and adolescence, producing learning problems and mood problems, and in adults for alterations of receptors for neurotransmission. It has been shown that N1-methyl pseudouridine binds to miR and alters their silencing processes, increasing cell methylome at the origin of cancer. The production of mRNA vaccines replaces Uridine with N1-methylpseudouridine to escape innate immunity and implement rapid translation. However, n1-methyl pseudouridine binds miR and alters the epigenetic transcription by silencing mRNA of oncosuppressors along with the increase in cell methylation, resulting in the induction of tumors and relapses, natural immunity inhibition, and neuro-behavioral disorders transmissible to progeny. Vectorial vaccines hybridize the host DNA with adenoviruses and, at the experimental level, induce tumors.
Please read the full article on Research Gate-pre-print
Question
I invite you to discuss the "Health Relativity Theory"
that you find in my presentation:
Thank you
Giuseppe R.Brera
Question
I invite you to discuss theories that you find in my presentation
Giuseppe R, Brera
Question
The review of the international literature on the hexavalent vaccination adverse effects, documents, without doubt, the existence of a new clinical syndrome: “The Post Hexavalent Vaccination Sudden Infant Death Syndrome ”, (PHVSIDS) without concurrent pathologies inducing a life risk confirmed by autoptic investigation, with an enhancement of the infant mortality and hospital admissions rates correlated to the number of vaccines before the first year of life.From 1999 to 2004, in Italy, there has been a slaughter of 52 infant deaths directly associated to hexavalent vaccination , 8 before 24 hours (RR= 1,5, RR= 2,3 with the Infarix Hexa vaccine- 0,7 with Hexavac ) , 34 within 7 days (RR=1,8- RR 1,5 with Infarix Hexa- 2,8 with Hexavac, with all the hexavalent products RR =2) 52 within 14 days (RR 1,5, RR= 1,5 with Infarix Hexa,1,6 with Hexavac). Children’s deaths notifications continued after this date. The hexavalent vaccination appears like a Russian Roulette in children with an unknown vulnerability. In addition to PHVSDS, there is the clinical and scientific evidence of auto-immune diseases, associated to vaccinations that derive from minerals added to vaccines as adjuvants, preservatives and stabilizers, like Aluminum , inoculated in enormous quantity, and Mercurium, that allows to define a new clinical Syndrome: the Post Vaccination ASIA Syndrome-PVAS). ASIA is the depicted Autoimmunity Syndrome Induced by Adjuvants . Moreover, there is an irrefutable documentation that hexavalent vaccination determines immunosuppression well depicted by immunology, a consequent cause of death from other infections, as happened .
The philosophy: " “ Let few deaths for saving much more lives " is unacceptable for a clinician, when in Public Health other preventive solutions are possible.
(From
The hexavalent vaccination Russian Roulette
The hexavalent vaccination risk for children’s and adults life . The introduction of The Post Hexavalent Vaccination Sudden Death Syndrome (PHVSIDS) and the Post Vaccination Asia Syndrome( PVAS). in Research Gate)
Question
According to Kuhn, a paradigm change in science, that means an epistemological change, requests the agreement of the scientific community, like it is arrived with the institution of quantum physics. In medicine a new paradigm of Medical Science has been proposed and applied in Medical Education in 1998 at the Milan School of Medicine , with the introduction of Person Centered Clinical Method and after the presentation of the new person centered interactionist and teleological health paradigm in 2005 ,presented at WHO (by invitation) in 2011 along with Person Centered Medicine, Medical Education change the paradigm change has been formalized on 13-14-15 October in Milan along with the presentation of “La Charte Mondiale de la Santé-the World Health Charter”.
The person-centered paradigm change of Medicine,Health, Medical Education and research corresponds to re-birth of clinics like a discipline addressed to discover the individuality of the patient in a disease and not the opposite, reducing him/her to an abstract theory. To date it is impossible because the same basic sciences , neurobiology, physiology, psycho-neuro- immune-endocrinology (PNEI) , already at experimental level, evidenced the end of a mechanistic , deterministic paradigm in Medical Science and the birth o f a person centered one (Person Centered Medicine) , that discriminates biological reactions, whose variability is determined by the person’s existential choices (life style and quality) from biological constants , responsible of biological life, according the Relativity Theory of Biological Reactions (1996)
I invite you to read the e-book “ Medical Science and Health Paradigm Change” and to give your “YES or NOT” about this paradigm change determinant for the destiny of Medicine , Medical Science and Medical Education, reformulating in a new way the epistemological principles of medicine, clinical method and clinical supervision
You can download the e-book from Research Gate:
And , if you agree ,to fulfill the agreement form or download it from www.healthparadigmchange.it sending it to secretariat@healthparadigmchange.it
And to read some other info on Person Centered Medicine on www.unambro.it
Thank you
Giuseppe R.Brera

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