Giuseppe Potrick StefaniPontifical Catholic University of Rio Grande do Sul | PUCRS · Escola de Ciências da Saúde e da Vida
Giuseppe Potrick Stefani
Professor
Postdoctoral fellow in UNIJUÍ
About
49
Publications
23,306
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
240
Citations
Introduction
Additional affiliations
January 2018 - July 2021
August 2016 - October 2020
March 2013 - June 2015
Education
December 2022 - December 2023
Publications
Publications (49)
Creatine supplementation is known to exert an effect by increasing strength in high intensity and short duration exercises. There is a hypothesis which suggests that creatine supplementation may provide antioxidant activity by scavenging Reactive Oxygen Species. However, the antioxidant effect of creatine supplementation associated with resistance...
The role of resistance training on collagen deposition, the inflammatory profile and muscle weakness in heart failure remains unclear. Therefore, this study evaluated the influence of a resistance training program on hemodynamic function, maximum strength gain, collagen deposition and inflammatory profile in chronic heart failure rats. Thirty-two m...
L-arginine supplementation has been related to increased maximum strength and improvement of hemodynamic parameters in several diseases. The aim of our study was to evaluate the effect of L-arginine supplementation and resistance training on muscle mass, hemodynamic function and DNA damage in healthy rats subjected to a low-arginine concentration d...
Background
Combined exercise training (CET) has been associated with positive responses in the clinical status of patients with heart failure (HF). Other nonpharmacological tools, such as amino acid supplementation, may further enhance its adaptation. The aim was to test whether CET associated with supplementing carnosine precursors could present b...
Highlights • Branched-chain amino acids could provide valuable nutrition for cancer patients. • Protocol for systematic review aims to evaluate if the supplementation is effective. • Only randomized clinical trials will be included in this protocol. Abstract Introduction: Cancer is a growing public health problem in the world. Poor nutrition is one...
Supplementation with antioxidant vitamins is common among amateur and elite athletes. It is thought to cause a reduction in the muscle damage that results from exercised-induced oxidative stress, increasing the ability to improve performance markers. A systematic review and meta-analysis were carried out to evaluate the effects of supplementation w...
Introduction: Protein Supplements Microparticles are crucial for their sensory properties and applicability in food production. This study has the objective to correlate protein particle length and content in different sources of protein supplements.
Methods: A analytical study with protein supplements from different sources was carried out to est...
Vitamin D is essential for the optimal health of the skeletal system. However, this vitamin also plays a role in other functions of the human body, such as muscle, immune, and inflammatory functions. Some studies reported that adequate levels of vitamin D improve immune system function by reducing the levels of certain pro-inflammatory cytokines, w...
The consumption of protein supplements is increasingly part of the everyday life of adults in general and is associated with a healthier lifestyle. However, a constant lack of commitment to the quality of these products by companies poses risks to consumers’ health. Therefore, this study aims to analyze the protein content and compare it with the n...
Resumo Introdução: A dieta vegetariana, alimentação baseada em plantas, se mostra eficiente no ganho de massa muscular, uma vez que contém alimentos de boa qualidade, resultando em benefícios para os praticantes de exercício físico de força. Objetivo: Realizar revisão integrativa de literatura sobre a influência da dieta vegetariana aplicada a prat...
Objective: This study aimed to compare the influence of a high carbohydrate meal versus high-fat meal on the oxidation of substrates during an exercise incremental test. Materials and methods: Ten untrained male subjects underwent two days of the protocol. Randomly, they received a high carbohydrate meal or a high-fat meal, receiving the other one...
Background: Withania somnifera has been used as an ergogenic resource in recent years. In this scenario, a systematic literature review is justified to compile the findings in the scientific literature and to evaluate the methodological quality of these investigations. Aims: Our objective with this review was to evaluate the effects of Withania som...
Atletas, o público fisicamente ativo e portadores de doenças crônicas buscam cada vez mais por suplementos alimentares proteicos para aumento de massa muscular. Este estudo tem como objetivo verificar a densidade energética, carboidratos, proteínas, sádio e aminoácidos essenciais nos rótulos de produtos de whey protein disponíveis no mercado bras...
Os aminoácidos de cadeia ramificada (BCAAs) ganharam muita popularidade nos últimos anos pelos praticantes de exercícios físicos e são facilmente encontrados em sites de e-commerce. A venda online está em uma crescente e a necessidade de informações sobre os produtos e suas composições é de grande importância tanto para os profissionais nutricion...
The purpose of this study was to evaluate the impact of high-intensity resistance training (RT) isolated or combined with continuous aerobic training (CAT) on cardiac remodeling and left ventricular dysfunction in healthy and heart failure (HF) rats. Forty-one male Wistar rats were divided into: (a) sedentary sham; (b) resistance training sham; (c)...
Vascular smooth muscle cells (VSMCs) exhibit a high degree of plasticity when they undergo the progression from a normal to a disease condition, which makes them a potential target for evaluating early markers and for the development of new therapies. Purinergic signalling plays a key role in vascular tonus control, ATP being an inductor of vasocon...
New findings:
What is the central question of the study? Does β-alanine with l-histidine supplementation associated with endurance and strength training improve echocardiographic parameters, functional capacity, and maximum strength in rats with chronic heart failure? What is the main finding and its importance? β-Alanine with l-histidine suppleme...
Background: Chronic heart failure (CHF) is a complex syndrome which comprises structural and functional alterations in the heart in maintaining the adequate blood demand to all tissues. Few investigations sought to evaluate oxidative DNA damage in CHF.
Objective: To quantify the DNA damage using the comet assay in left ventricle (LV), lungs, diaph...
Analysis of protein concentration in different types of national protein supplements The consumption of nutritional supplements such as whey protein has been constantly increasing among athletes and physical exercise practitioners. It is extremely important for the consumer that the nutritional information contained in these labels are according to...
The aim was to perform a review in order to elucidate the actions and efficacy of different antioxidant supplements used on Metabolic Syndrome. The articles were searched during October of 2015 to December of 2018, using the databases PubMed and Web of Knowledge. The keywords used were: "Metabolic Syndrome" AND "dietary supplements" OR "antioxidant...
Effects of supplementation of ômega-3 fatty acids on late muscular pain: a systematic review Delayed onset muscular pain (DOMS) is characterized by stiffness and edema of the muscular bed, pain or discomfort in the musculature to the touch or movement, implying in the diminution of the range of movement, being able to negatively impact the performa...
Data of biochemical analyses, hemodynamic parameters and strength gain.
(XLSX)
Background:
Resistance training (RT) has been associated with positive responses in patients with cardiovascular disease, and when it is combined with continuous aerobic training (CAT), favorable adaptations appear to be even more pronounced. However, the effects of high-intensity RT alone or in combined with CAT in the case of heart failure (HF)...
Respiratory muscle training (RMT) promotes beneficial effects on respiratory mechanics, heart and lung morphological changes, and hemodynamic variables in rats with heart failure (HF). However, the relation between RMT effects and diaphragm oxidative stress remains unclear. Therefore, the aim of this study was to evaluate the RMT effects on diaphra...
New Findings
What is the central question of this study?
To the best of our knowledge, no studies have evaluated oxygen uptake, carbon dioxide production and exercise tolerance in rats that have undergone myocardial infarction classified by myocardial infarct (MI) size.
What is the main finding and its importance?
Oxygen uptake and exercise intoler...
Exercise tolerance and maximal oxygen uptake (VO2max) are reduced in heart failure (HF). The influence of combined resistance training (RT) and low-level laser therapy (LLLT) on exercise tolerance and VO2max in HF has not yet been explored. The aim of this study was to evaluate the influence of combined RTand LLLT on VO2max and exercise tolerance i...
Weight loss supplements are often used by those who wish to accelerate body fat oxidation. Most of these supplements are caffeine-based, but frequently uses other ingredients in order to increase energy expenditure. Few studies aimed to investigate the possible dose-response of isolated caffeine on metabolism in humans. To evaluate the use of isola...
The aim of the present study was to compare the effects of continuous versus interval aerobic exercise training on hemodynamic parameters, cardiac remodeling, and maximal exercise capacity (MEC) in chronic heart failure (CHF) rats.
Twenty-four male Wistar rats were subjected to myocardial infarction (MI) surgery. Five weeks post MI, the animals wer...
The Metabolic Syndrome (MetS) is a complex condition which is characterized by increased risk factor for cardiovascular diseases, such as dyslipidemia, hypertension and central obesity, in addition to increased risk for type 2 diabetes mellitus (T2DM). All of these factors alone have a notable relationship with DNA damage. However, when the risks a...
The effects of creatine supplementation related to ergogenic action which increases maximum strength and body mass has been extensively revised. In the last years it has been hypothesized a novel function of creatine as antioxidant agent. There are few data of this amine on oxidative stress and its role in antioxidant system. A small amount of stud...
Journal of Nutritional Health & Food Engineering of two oxidants in endothelium: the superoxide anion-radical (O 2 - •) and peroxynitrite (ONOO -). These both free radicals are associated with the development of endothelial disfunction [4]. Under normal conditions, endothelium produces NO by Arg in the presence of oxygen catalyzed by eNOS. The NO d...
Purpose: The creatine supplementation (CS) exerts effect on increasing strength in high intensity and short duration exercises, and may perform an antioxidant activity by scavenging reactive oxygen and nitrogen species. Notably, is observed that physical training can increase the modulation of catalase (CAT) activity. We investigated the effect of...
The aim of this study was to investigate the impact of whey protein (WP) supplementation and resistance training (RT) on liver and kidney biomarkers. The sedentary + WP group showed higher levels of plasma liver and kidney dysfunction markers compared with the other groups. In addition, WP supplementation associated with RT resulted in physiologic...
The resistance training is known by causing different adaptations like fiber II hypertrophy, predominantly, as well as the increasing of glycolytic enzyme activity and of the creatine phosphate system. The creatine monohydrate seems to have positive effects on the improvement of muscular maximum strength. The present study had the objective of anal...
Questions
Questions (6)
Any help would be very appreciated!
I need help to search the best and most feasible methods to quantify carnosine content in skeletal muscle of rats. Any suggestion is welcome!
Once Detox diets have gained tremendous attention, people used it as the miracle pill. It does seem to be more an empirical practice than an evidence-based nutritional intervention for weight loss. I found in the majority of published studies, researches that administered a toxic substance, not a diet for desintoxication in healthy subjects. In almost all cases of Detox diets, the subject is not poisoned or intoxicated for following such a diet.
What does the scientific studies shows? Is there a scientific base in this type of diet?
Hope to hear your comments.
Giuseppe PS
There are investigations that shows alterations in testosterone levels of athletes in overtraining, as well as in other biochemical, physiological and psychological parameters.
Since the diagnosis of overtraining is difficult to establish, because it is directly and indirectly related to several factors, my question is: is there other alterations previously reported in the literature in heat shock proteins, DNA damage, vascular or cardiac alterations in athletes that are experiencing overtraining?
I want to learn a possible method for measuring GPx activity that uses other catalase inhibitor. I saw that aminotriazole (3-Amino-1,2,4-triazole) is a irreversible catalase inhibitor, however I don't know its application for measuring GPx activity. Any help will be very appreciated.
I have been searching for the best software to acquire more variables from the comet assay. Yet, I have not had good results of a reliable software. Any examples or ideas to present would be greatly appreciated.
