Gisèle Li

• Université de Montréal

Purpose To determine whether self-reported race/ethnicity is associated with intraocular pressure (IOP) and glaucoma and to explore whether any associations are due to social, behavioral, genetic, or health differences. Design Cross-sectional analysis of population-based data. Methods We used the Canadian Longitudinal Study on Aging Comprehensive...

Purpose: The purpose of this study was to examine the association of alcohol consumption with intraocular pressure (IOP) and glaucoma and to assess whether any associations are modified by a glaucoma polygenic risk score (PRS). Methods: Cross-sectional analysis of data from the Canadian Longitudinal Study on Aging Comprehensive Cohort, consistin...

Purpose: We synthesized the literature on the association between systemic antihypertensive medications with intraocular pressure (IOP) and glaucoma. Antihypertensive medications included beta blockers (BB), calcium channel blockers (CCB), angiotensin converting enzyme inhibitors (ACEi), angiotensin receptor blockers (ARB), and diuretics. Design:...

Purpose: Studies examining the apolipoprotein E (APOE) ε4 allele and glaucoma are inconsistent, which could be due to interactions with other factors. We examined the relationship between the APOE ε4 allele and glaucoma and intraocular pressure in a large, population-based random sample and explored whether the APOE ε4 allele interacted with syste...

Purpose To examine the longitudinal association between vision-related variables and the 3-year change in cognitive test scores in a community-dwelling sample of adults and to explore whether sex, education, or hearing loss act as effect modifiers. Methods Data came from two waves of a 3-year population-based prospective cohort study (Canadian Lon...

Purpose: To determine the relationship between fine particulate matter (PM2.5) and ocular outcomes such as visual impairment and age-related eye disease. Methods: Baseline data were used from the Canadian Longitudinal Study on Aging. The Comprehensive Cohort consisted of 30,097 adults ages 45 to 85 years. Annual mean PM2.5 levels (µg/m3) for eac...

Purpose Age-related eye disease may be associated with cognitive decline, but the scientific literature has not been consistent. Furthermore, no studies have been able to explain the relationship. Our objective was to assess whether older adults with age-related macular degeneration (AMD) or glaucoma performed worse on 6 cognitive tests compared wi...

Studies have found a benefit to living a cognitively active life in older age. Our goal was to quantify participation in cognitively stimulating activities in adults with and without age-related eye disease. We conducted a cross-sectional hospital-based study in Montreal, Canada of older adults (n = 303) having either age-related macular degenerati...

The identification of modifiable risk factors for glaucoma progression is needed. Our objective was to determine whether maladaptive coping styles are associated with recent glaucoma progression or worse visual field mean deviation. A hospital-based case–control study was conducted in the Glaucoma Service of Maisonneuve-Rosemont Hospital in Montrea...

To estimate the diagnostic accuracy of the GDx-VCC for glaucoma screening in a population with ≥1 risk factors for glaucoma. Cross-sectional evaluation of a diagnostic test for screening. Two hundred forty-seven community-based volunteer participants with risk factors for glaucoma. The peripapillary retinal nerve fibre layers (RNFL) of participants...

Purpose: Theoretical models and animal studies have suggested that scleral rigidity plays an important role in the pathogenesis of glaucoma. The aim of this study was to present a noninvasive technique for estimating ocular rigidity (E) in vivo, and to compare the estimated rigidity between patients with open-angle glaucoma (OAG); ocular hypertens...

To describe a novel surgical technique for drainage of bullous serous and hemorrhagic choroidal detachments. A prospective, consecutive case series of 6 eyes with serous and/or hemorrhagic choroidal detachments secondary to intraocular surgery was documented to evaluate the feasibility of using the 25-gauge and 20-gauge transconjunctival trocar/can...

To determine if the difference in intraocular pressure (IOP) measurements between dynamic contour tonometry (DCT) and Goldmann applanation tonometry (GAT) is correlated with axial length (AL), and to assess the possible influence of age, sex, central corneal thickness (CCT), corneal hysteresis (CH), ocular pulse amplitude (OPA), and glaucoma status...

To evaluate whether a single frequency doubling perimetry (FDT) test is a valid screening tool to detect open-angle glaucoma (OAG) in high-risk populations. All participants underwent frequency doubling Technology perimetry (FDT C-20-5 algorithm, Carl Zeiss Meditec Inc, Dublin, CA) and complete ophthalmic examination. FDT printouts were classified...

To estimate the diagnostic accuracy of Stratus optical coherence tomography (OCT) for glaucoma screening in high-risk populations. Cross-sectional evaluation of a diagnostic test for screening. Three hundred thirty-three community-based volunteer participants with risk factors for glaucoma. The optic nerve and peripapillary retinal nerve fiber laye...

To report 4 cases of recurrent anterior uveitis occurring 1-11 months after trabeculectomy with mitomycin C. Observational case series. Four patients in whom recurrent uveitis developed after trabeculectomy with mitomycin C, followed at Maisonneuve-Rosemont Hospital in Montreal, Quebec. Retrospective review of the medical records. One to 11 months...

Topical and systemic corticosteroids are well known to raise intra-ocular pressure while the effect of inhaled corticosteroids (ICS) on the risk of glaucoma remains uncertain. We sought to determine the risk of new onset ocular hypertension or glaucoma requiring treatment, associated with the use of ICS in elderly patients treated for airways disea...

To use optical coherence tomography (OCT) to identify the specific retinal layers and macular regions damaged in glaucoma. Observational cross-sectional study. One hundred forty-nine participants in the Advanced Imaging for Glaucoma Study, divided into 3 groups: normal (N) perimetric glaucoma (PG), and glaucoma suspect and preperimetric glaucoma (G...

To describe the use of amniotic membrane (AM) transplantation for the repair of conjunctival buttonholes during trabeculectomy with mitomycin C. Four eyes of 3 patients with thin conjunctiva, precluding watertight conjunctival closure at the incision site with suturing, underwent intraoperative AM grafts over the leaking areas. In all eyes, a funct...

To report a case in an adult of xanthogranuloma of the iris that clinically simulated iris melanoma. Observational case report. Clinical and histopathologic examination of iris mass obtained from a 77-year-old white woman. High-frequency ultrasonography of the right eye revealed a small, echodense lesion involving the iris root. The mass revealed h...

To describe the results of a novel postoperative management approach for patients undergoing combined cataract and glaucoma surgery supplemented with early needle revision and antimetabolites. Consecutive retrospective chart review identified 66 patients who had undergone combined cataract and glaucoma surgery with early needling and antimetabolite...

Endogenous Klebsiella endophthalmitis is known to occur in adults with suppurative liver disease, diabetes, or urinary tract infections.1 To our knowledge, endogenous Klebsiella endophthalmitis has not been reported in neonates. We report one case of unilateral endogenous endophthalmitis presumed to be secondary to Klebsiella pneumonia sepsis in a...