Giorgio Maria Calori

Giorgio Maria Calori
University of Milan | UNIMI · Reparative Orthopaedic Surgery

Prof., M.D.

About

285
Publications
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13,178
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Publications

Publications (285)
Article
Full-text available
Background The purpose of this work is to characterize the anatomy of the intraarticular portion of the long head of the biceps tendon (long head biceps tendon) using magnetic resonance (MR) arthrography by investigating whether anatomical variants may facilitate the onset of a supraequatorial lesion (superior labral anterior to posterior, SLAP)....
Article
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Highlights Prosthetic joint infections (PJI) represent one of the major problems in orthopedic prosthetic surgery. The diagnosis of prosthetic infections requires a multispecialist approach, from accurate anamnestic collection, to clinical evaluation and biomarkers of inflammation, to the use of imaging techniques. The identification of the bacteri...
Article
Fractures of the pelvic ring and acetabulum generally result after high energy trauma. Pelvic fractures, especially, are considered complex injuries from a therapeutic point of view, in relation to the frequent coexistence of skeletal and / or parenchymal lesions affecting other areas, and the abundant bleeding invariably associated with the latter...
Article
Background: Most models for outcome prediction in heart failure are under-utilized because complex or including non-routine clinical use variables. We aimed to develop a prognostic score for patients with stable heart failure, including only easily obtainable parameters. Methods: In 376 outpatients with heart failure (ejection fraction ≤40%), tw...
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Background: Hand hygiene is the primary preventive measure against health care-associated infections in terms of cost-effectiveness. In 2005, the WHO proposed the "Global Patient Safety Challenge" campaign, with the aim of reducing the overall incidence of such infections, through multimodal programs and strategies, interactive training tools and...
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During the Trauma Meeting 2017 in Riccione an important Round Table took place entitled “Analysis of the epicrisis and development of effective organizational models” within the session “Fast-track of proximal femur fractures in patients over 65 years”. Given the great relevance of the topic and the precious contribution of the participants, it was...
Article
The incidence of periprosthetic fractures of the femur associated with total hip and total knee arthroplasty varies in different studies. Overall rates have been estimated at 2 to 5%. Although infrequent, periprosthetic femoral non-unions create a debilitating condition for the patient. To date, the literature on the surgical management of femoral...
Article
Introduction Open reduction and internal fixation (ORIF) with plate and screws represents the recommended treatment for unstable intra-articular distal radius fractures. Although significant progresses in surgical technique have been made, anatomical reconstruction of radio-carpal articular surface still represent a difficult task, especially in mu...
Article
Proximal femoral fractures in elderly patients represent a rapidly increasing socio-economic problem. The functional recovery and the mortality rate are influenced by a substantial quantity of variables, including the waiting time for surgical treatment (“time to surgery”). This study aims at investigating the average waiting time, and ascertaining...
Article
The gold standard technique for treating non-union of the clavicle is based on corticocancellous bone graft harvested from the iliac crest and fixation with a plate. In cases of large clavicular defects, this surgical procedure becomes ineffective and only a complex bone reconstruction can be considered. In the herein study we report on a clavicula...
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Non-union of long bones is a significant consequence of fracture treatment. Bone regeneration is a complex physiological process of bone formation which can be seen during normal fracture healing. An improved understanding of the molecular and cellular events that occur during bone repair and remodelling has led to the development of biologic agent...
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Avascular necrosis (AVN) of the femoral head (FH) causes 5% to 12% of total hip arthroplasties (THA). It especially affects active male adults between the third and fifth decades of life. The exact worldwide incidence is unknown. There are only few data related to each country, but most of it relates to the United States. Non-surgical management ha...
Article
Introduction: Latest advances made in joint replacement implants allows reconstruction of entire limbs. These special prostheses or megaprostheses were originally designed for the treatment of severe oncological bone loss. Nowadays, however, the indications and applications of these devices are expanding to other orthopaedic and trauma clinical co...
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Purpose: Reamer-irrigator-aspirator (RIA) is an innovative device that its indications have recently been expanded to the management of long bone infections. Methods: In this narrative review, we summarise the most important studies in the field and we present the current open questions pertaining to the use of RIA in the management of osteomyel...
Article
Necrosis of the humeral head, infections and non-unions are among the most dangerous and difficult-to-treat complications of proximal humeral fractures. The aim of this work was to analyse in detail non-unions and post-traumatic bone defects and to suggest an algorithm of care. Treatment options are based not only on the radiological frame, but als...
Article
Introduction: Proximal humeral fractures with a spiral line of fracture extending from the humeral head to the diaphyseal region are increasing. Treatment for these fractures is comparable to that for shaft fractures. The purpose of this study was to evaluate the use of a new "Long" humeral nail for this type of lesion and identify the best distal...
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Background Bone tissue engineering and the research surrounding peptides has expanded significantly over the last few decades. Several peptides have been shown to support and stimulate the bone healing response and have been proposed as therapeutic vehicles for clinical use. The aim of this comprehensive review is to present the clinical and experi...
Article
This project aims to develop a model for assessing the direct cost of SSIs borne by the hospital and the regional health service. The study was run by the Gaetano Pini Orthopaedic Institute in partnership with Aon Hewitt Risk & Consulting AGRC Italy and the University of Milan. Seven patients who developed an SSI during the ISChIA active prospectiv...
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Bone density insufficiency is the main cause for significant musculoskeletal trauma in the elderly population following low-energy falls. Hip fractures, in particular, represent an important public health concern taking into account the complicated needs of the patients due to their medical comorbidities as well as their rehabilitation and social d...
Article
The surgical treatment of forearm fracture nonunions remains a therapeutic challenge for orthopedic trauma surgeons. Nonunions of the forearm diaphysis, although not frequent, cause severe anatomic and functional impairment related to disturbance of the interosseous membrane and dysfunction of the adjacent elbow and wrist joints. Lately the induced...
Article
Current evidence, based primarily on case series, suggest that the eptotermin alfa (recombinant bone morphogenetic protein-7 (rhBM-7)), which is commercialized as Osigraft with an indication for tibial non-union, used in monotherapy or polytherapy, is a safe and effective therapy for long bones non-unions of lower and upper limbs. No previous study...
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Deep vein thrombosis (DVT), with its complications, is a common, serious and potentially fatal disease; it aggravates the course of patients undergoing elective surgery, even more so in case of trauma; considering its frequently binding and urgent nature, it has to be specifically prevented.
Article
Megaprostheses were developed for the treatment of severe oncological bone loss. We present an analysis of results and complications during and after implantation of megaprosthesis based on our experience in the treatment of acute traumatic and post-traumatic bone loss in non-oncological patients.
Conference Paper
Introduction: Our department is responsible specifically for complex cases resulting from trauma. Our experience aims to demonstrate how the use of this molecule was effective not only in THA-TKA but also in mega-prosthesis and how it has proven to be flexible and safe in dealing with difficulties and surgical complications more common in such diff...
Article
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Over the years, the Gaetano Pini Orthopaedic Institute has implemented several projects in the hope of preventing healthcare-associated infections (HAIs). In particular, the institute participated in a long-term project monitoring arthroplasty-associated SSIs in 2010 (the ISChIA study), funded by the Italian Society of Hygiene’s GISIO (the Italian...
Conference Paper
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Objective: to determinate the efficacy of core decompression technique with the use of recombinant morphogenetic proteins, autologous mesenchimal stem cells (MSCs) and xenograft bone substitute into the necrotic lesion of the femoral head on clinical symptoms and on the progression of osteonecrosis of the femoral head. Methods: we studied 38 patie...
Conference Paper
Introduction: Ruptures in ligaments and tendons may occur as a result of repetitive motion and traumatic or sports-related accidents. Unfortunately, the ligaments and tendons have relatively poor vascular supply and have no ability to heal a complete tear. We present out experience intended to strengthen weak or repaired soft tissue in different ca...
Conference Paper
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INTRODUCTION The 5-10% of all fractures is associated with healing problems resulting in delayed union or nonunion development. The aim of this study is to assess what might be the most appropriate therapeutic strategy in the treatment of nonunions and bone defect of the forearm. In particular we want to determine whether, in a bone segment such as...
Conference Paper
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From January 2010 to date DVT prophylaxis in THR / TKR and revision was routinely performed with rivaroxaban. To date, over 200 cases of first implant/revision in THR/TKR and about 20 cases of large segments replacements have not been highlighted complications attributable to rivaroxaban. Our department is responsible specifically for complex cases...
Article
The incidence of fracture non-union has been estimated to be as high as 10 %. The treatment of fracture non-union remains challenging even for the most experienced surgeons. The presence of a poor soft tissue envelope, deformity, avascular bone edges, reduced bone stock, low-grade infection and patient related co-morbidities are some of the importa...
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Studies have estimated that 5–10% of all fractures are associated with impaired healing, resulting in delayed union or non-union. Bone defects can result from a high-energy traumatic event, from large bone resection for different pathologies such as tumours or infections or from the treatment of complex non-unions. A large bone defect represents a...
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In the Department of Micro-surgery of the hand are made interventions identified by regional legislation as “low-complexity care interventions” (BOCA). For this reason, as pilot experience, it has been decided to apply Diagnostic Therapeutic Path (PDT) to this type of interventions in order to improve the offered service. From 2011 to 2012 we colle...
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Increases in life expectancy, active population and survival to road accidents create a growing population of patients with traumatic pathology, and therefore of nonunions. A proper surgical treatment appears an essential condition to obtain the necessary initial stability, that is the basis of the healing process. But now it clearly appears that t...
Article
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A new scoring system is proposed in order to assist surgeons with the complex analysis associated with non-union surgery. Patients with non-union are rarely easily compared with one another and this has frustrated research in this field. We have therefore attributed values to clinical features based on clinical experience and research evidence, so...
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The long bone nonunions and critical bone defects are two of the more difficult complications to treat. We treated a 59 years old patient that came to our attention through the ambulatory of nonunion of our institute with a diagnosis of distal femoral nonunion on the left side: the patient had undergone previous osteosynthesis with plate and screws...
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Bone regeneration presents a unique challenge to both clinicians and scientists. Recently, a vast amount of knowledge has been attained with regard to the molecular mediators, cell populations and the overall cascade of events participating in the bone repair processes. For the treatment of bone non-unions or bone defects, the ‘Diamond Concept’ for...
Article
In traumatologia e ortopedia, l’innesto di tessuto osseo viene frequentemente effettuato per facilitare la rigenerazione ossea. L’innesto di osso autologo è tuttora il “gold standard” e il sito di prelievo più comune rimane la cresta iliaca. La recente introduzione di un nuovo “device”, il “reamer irrigator aspirator” (RIA), consente di prelevare t...
Article
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Lo sviluppo di nuove megaprotesi per il trattamento di grandi difetti ossei ha offerto importanti opportunità ai chirurghi ortopedici oncologi per la sostituzione di grandi segmenti scheletrici, come le ossa lunghe degli arti superiori e inferiori e le relative articolazioni. La nostra esperienza clinica nel trattamento di pseudoartrosi e grave per...
Article
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Avascular necrosis of the femoral head (AVN) is a common cause of hip disability that, if left untreated, may cause collapse of femoral head and secondary hip osteoarthritis in up to 80% of patients. Osteonecrosis of the femoral head typically affects patients in their third-to-fifth decades of life and often, in 50% of these patients, the disease...
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Abbiamo trattato un paziente di 47 anni giunto alla nostra osservazione tramite il Servizio Traumatologico d’Urgenza del nostro Istituto con diagnosi di frattura di trochine dalla testa omerale destra in paziente sottoposto a stabilizzazione della spalla omolaterale con tecnica secondo Letarjet nel 1993. Il paziente pertanto è stato sottoposto a in...
Article
L’innesto osseo autologo è stato a lungo considerato il gold standard per il ripristino dei difetti ossei. Tuttavia questa procedura si associa nel tempo allo sviluppo di un alto tasso di complicazioni senza, peraltro, garantire benefici clinici assoluti. Per questo motivo la ricerca si è concentrata negli ultimi anni sullo sviluppo di sostituti os...
Article
Osteonecrosis of the femoral head (up to Stage IIIC of the Steinberg classification system). Patients under 55 years of age. No presence of radiological-documented arthritis of the hip.
Article
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Immediate total hip replacement (THR) in patients with acetabular fractures is controversial because of concerns about high complication rates. The current article is a systematic review of the literature on the use of acute THR for the treatment of acetabular fractures. This systematic review included studies published in English between 1992 and...
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The etiologies of osteonecrosis of the talus are numerous. Use of corticosteroids, alcohol abuse, systemic lupus erythematosus, kidney transplantation, sickle cell anemia, hyperlipidemia, irradiation and inherited thrombophilia are typical of atraumatic forms. Fractures and dislocations of the talar neck are responsible for most traumatic forms.The...
Article
Autograft is considered the gold standard in non-union treatment. However, it is associated with significant morbidity and limited biological activity. The introduction of bone morphogenetic proteins (BMPs) has added a valuable tool to the surgeon's possibilities. The initial expectations of the effectiveness of BMPs were high, but over the years t...
Article
Objective To determinate the efficacy of “polytherapy”, a surgical technique that utilize all the components of the diamond concept (mesenchymal stem cells, bone morphogenetic proteins and scaffold) versus a “monotherapy”, a surgical technique that utilize only one component of the diamond conceptin the treatment of severe forearm non-unions.Method...
Article
Background Subtrochanteric femoral non-unions in the setting of failed metalwork pose a challenging clinical problem. This study assessed the clinical outcome of patients treated according to the principles of the “Diamond” concept.Methods Between 2007 and 2011 all patients presented with a subtrochanteric atrophic aseptic non-union in the setting...
Article
Fractures of the humerus in patients with total shoulder replacement are rare and difficult to treat. The treatment of periprosthetic humeral fractures depends on the location of the fracture in relation to the humeral stem and the stability of the stem/bone interface. We wished to determine the treatment outcomes in a series of patients managed in...
Conference Paper
The third fragment, mainly in the diaphyseal fractures or juxta articular, is often a time of choice of surgical technique, postoperative management of the patient and any medical decisions or other therapeutic proposals. A series of complex open questions and decision points not always easily standardized and classified. The third fragment is the...
Data
Objective To evaluate the feasibility of the Adamkiewicz artery (AKA) detection by multidetector computed tomography (CT) data analysis without the need of a dedicated workstation, using low-cost hardware and the freeware OsiriX.
Article
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ne-gativa per patologie reumatiche, ortopediche, genetiche e disme-taboliche. Paziente attivo, nor-mopeso (BMI 20,7: 1,77 m per 65 kg), non fumatore, non abu-so di alcool. Il 17/07/2011 il paziente riferiva di essere stato coinvolto in inci-dente sportivo (caduta da delta-plano) a seguito del quale ripor-tava trauma contusivo della spal-la sinistra...
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The "Diamond concept" 3 , later evolved into the "Pentagon" one, clarifies the importance of all the factors that can lead to healing nonunion. Then the activity of scientific research has focused to identify a selective 4 and circumscribed area where it was possible the occurrence of the biological process of healing; this is the "bio-logical cham...
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consultants. As long as bone repair and regeneration is considered as a complex clinical condition, the diamond concept, later evolved into the pentagon's one, is the theo-retical and practical basis for the bone healing. The effec-tiveness or not of bone morphogenetic proteins (BMPs) in association with other growth factors and with mesenchy-mal s...
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Full-text available
ABSTRACTNonunion risk factors Increases in life expectancy, active population and survival to road acci-dents create a growing population of patients with traumatic pathology,and therefore of nonunions. A proper surgical treatment appears an essen-tial condition to obtain the necessary initial stability, that is the basis of thehealing process. But...
Article
Le pseudoartrosi (PSA) e le perdite di sostanza ossea juxta-articolari sono una rara complicanza in ortopedia e traumatologia, ma rappresentano situazioni assai impegnative dal punto di vista clinico e della scelta del trattamento. Alcuni problemi coesistenti, come l’osteoporosi, la deformità, l’atrofia dei tessuti molli, l’eventuale presenza di in...