
Giorgi ChakhunashviliNational Center for Disease Control and Public Health | NCDC · Communicable Disease Department
Giorgi Chakhunashvili
PhD
About
29
Publications
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312
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Publications
Publications (29)
Introduction
Understanding COVID-19 vaccine effectiveness (VE) in healthcare workers (HCWs) is critical to inform vaccination policies. We measured COVID-19 VE against laboratory-confirmed symptomatic infection in HCWs in the country of Georgia from January – June 2022, during a period of Omicron circulation.
Methods
We conducted a cohort study of...
Background
Healthcare workers (HCWs) have suffered considerable morbidity and mortality during the COVID-19 pandemic. Few data on COVID-19 vaccine effectiveness (VE) are available from middle-income countries in the WHO European Region. We evaluated primary series COVID-19 VE against laboratory-confirmed COVID-19 among HCWs in Georgia.
Methods
HCW...
Background Healthcare workers (HCWs) have suffered considerable morbidity and mortality during the COVID-19 pandemic. Few data on COVID-19 vaccine effectiveness (VE) are available from middle-income countries in Europe. We evaluated primary series COVID-19 VE against laboratory-confirmed COVID-19 among HCWs in Georgia. Methods HCWs in six hospitals...
Background Healthcare workers (HCWs) have suffered considerable morbidity and mortality during the COVID-19 pandemic. Few data on COVID-19 vaccine effectiveness (VE) are available from middle-income countries in Europe. We evaluated primary series COVID-19 VE against laboratory-confirmed COVID-19 among HCWs in Georgia. Methods HCWs in six hospitals...
Background
Georgia has adopted the World Health Organization European Region's and global goals to eliminate viral hepatitis. A nationwide serosurvey among adults in 2015 showed 2.9% prevalence for hepatitis B virus (HBV) surface antigen (HBsAg) and 25.9% for antibodies against HBV core antigen (anti-HBc). HBV infection prevalence among children ha...
Background:
The country of Georgia initiated its hepatitis C virus (HCV) elimination program in 2015, at which point a serosurvey showed the adult prevalence of HCV antibody (anti-HCV) and HCV RNA to be 7.7% and 5.4%, respectively. This analysis reports hepatitis C results of a follow-up serosurvey conducted in 2021, and progress towards eliminati...
This study has evaluated the correlation between different carbapenemases detection methods on carbapenem non-susceptible Klebsiella pneumoniae strains from Northern and Eastern Europe; 31 institutions in 9 countries participated in the research project, namely Finland, Estonia, Latvia, Lithuania, Russia, St. Petersburg, Poland, Belarus, Ukraine, a...
Objective
Identify cases of West Nile virus in Black Sea region of Georgia through active surveillance.IntroductionArbovirus infections are causing enormous global burden, while their geographic distribution expands and affects new regions and areas. West Nile virus (WNV), one of the most important pathogens among arboviruses, was historically asso...
Background
Severe Acute Respiratory Infection (SARI) causes substantial mortality and morbidity worldwide. The country of Georgia conducts sentinel surveillance to monitor SARI activity and changes in its infectious etiology. This study characterizes the epidemiology of SARI in Georgia over the 2015/16 and 2016/17 influenza seasons, compares clinic...
Background
Influenza epidemiological and virologic data from Georgia are limited. We aimed to present Influenza Like Illness (ILI) and Severe Acute Respiratory Infection (SARI) surveillance data and characterize influenza viruses circulating in the country over three influenza seasons.
Methods
We analyzed sentinel site ILI and SARI data for the 20...
Map of Georgia.
Sentinel site cities are marked in dark green.
(TIF)
NA gene phylogeny of influenza A(H3N2) viruses detected in Georgia during three influenza seasons 2014–2017.
Virus annotation is as for Fig 5.
(TIF)
HA gene phylogeny of influenza B/Yamagata lineage viruses detected in Georgia during the 2014–2015 influenza season.
Vaccine viruses are indicated in red, viruses from Georgia in the 2014–2015 season are shown in blue. Reference and vaccine viruses against which post-infection ferret antisera were raised for use in HI assays are in bold type. The s...
HA and NA sequence accession numbers for all reference and test influenza viruses.
(XLS)
Influenza-associated deaths during 2014–2017 influenza seasons, Georgia.
(TIF)
NA gene phylogeny of influenza A(H1N1)pdm09 viruses detected in Georgia during 2014–2015 and 2015–2016 influenza seasons.
Virus annotation is as for Fig 4.
(TIF)
NA gene phylogeny of influenza B/Yamagata lineage viruses detected in Georgia during the 2014–2015 influenza season.
Virus annotation is as for S4 Fig.
(TIF)
NA gene phylogeny of influenza B/Victoria lineage viruses detected in Georgia during 2015–2016 and 2016–2017 influenza seasons.
Virus annotation is as for S6 Fig.
(TIF)
HA gene phylogeny of influenza B/Victoria lineage viruses detected in Georgia during 2015–2016 and 2016–2017 influenza seasons.
Vaccine virus is indicated in red; 2015–2016 and 2016–2017 viruses from Georgia in pink and brown respectively. Reference and vaccine viruses against which post-infection ferret antisera were raised for use in HI assays ar...
Infections caused by viruses of the parapoxvirus (PPV) genus, including orf and pseudocowpox viruses, are frequently seen in both humans and animals in many regions of the world. These infections are often misdiagnosed or neglected because of the lack of clinician awareness, inadequate diagnostic capacity, and their relatively mild disease presenta...
Objectives:
Due to reports of substandard influenza preparedness, the country of Georgia developed two influenza surveillance systems. This paper describes these surveillance systems in their capacity to detect influenza.
Methods:
Two surveillance systems for influenza operate in Georgia: an influenza-like illness (ILI) sentinel surveillance sys...
Background:
Leishmaniasis includes multiple clinical syndromes, most notably visceral, cutaneous, and mucosal forms. Visceral leishmaniasis (VL), also known as kala-azar, is a potentially fatal disease endemic to large parts of Africa and Asia, and in South-Eastern Europe (Greece, Turkey, Georgia). Visceral leishmaniasis is a parasitic zoonosis ca...
Background
The 2009 H1N1 pandemic highlighted the need to routinely monitor severe influenza, which lead to the establishment of sentinel hospital-based surveillance of severe acute respiratory infections (SARI) in several countries in Europe. The objective of this study is to describe characteristics of SARI patients and to explore risk factors fo...
This study investigated the transmission and prevalence of Leishmania parasite infection of humans in two foci of Visceral Leishmaniasis (VL) in Georgia, the well known focus in Tbilisi in the East, and in Kutaisi, a new focus in the West of the country. The seroprevalence of canine leishmaniasis was investigated in order to understand the zoonotic...