Gillian L Allison

Gillian L Allison
University of the West Indies, St. Augustine | UWI · Faculty of Medical Sciences

B.Sc. (Hons) Biomedical Science, M.Sc. Immunology & Allergy, Ph.D Biochemistry, PgCert University Teaching & Learning

About

13
Publications
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230
Citations

Publications

Publications (13)
Article
Background and purpose Blended learning (BL) integrates face-to-face and online instructional methods, with applications in pharmacy education. This study aimed to assess pharmacy students’ perceptions of BL in a pharmacy seminar course at The University of the West Indies, St. Augustine campus, Trinidad and Tobago. Educational activity and settin...
Article
Abstract: An online survey was distributed to first-year pharmacy students in Trinidad and Tobago, to evaluate their experiences using adaptive learning technology in the form of a SmartBook for an Anatomy and Physiology course. Fifty percent of the students sampled completed the survey. Respondents reported spending approximately five hours per w...
Poster
Abstract: An online survey was distributed to first-year pharmacy students in Trinidad and Tobago, to evaluate their experiences using adaptive learning technology in the form of a SmartBook for an Anatomy and Physiology course. Fifty percent of the students sampled completed the survey. Respondents reported spending approximately five hours per w...
Article
Full-text available
Although the etiology of squamous cell carcinomas of the oral mucosa is well understood, the cellular origin and the exact molecular mechanisms leading to their formation are not. Previously, we observed the coordinated loss of E-cadherin (CDH1) and transforming growth factor beta receptor II (TGFBR2) in esophageal squamous tumors. To investigate i...
Article
Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC We previously observed that 70% of esophageal tumors demonstrated coordinated loss of E-cadherin and TGFβRII. When grown in three-dimensional organotypic reconstruct cultures, cells lacking E-cadherin and TGFβRII demonstrate fibroblast-dependent invasion into the underlyin...
Article
Aims: Increased platelet aggregation plays an important role in the etiology of cardiovascular disease. Garlic inhibits platelet aggregation; however, the mechanisms involved have not clearly been defined. This study was undertaken to investigate the mechanisms by which an aged garlic extract (AGE) inhibits both the activation and aggregation of h...
Article
Full-text available
E-cadherin is frequently lost during epithelial-mesenchymal transition and the progression of epithelial tumorigenesis. We found a marker of epithelial-mesenchymal transition, CD44, upregulated in response to functional loss of E-cadherin in esophageal cell lines and cancer. Loss of E-cadherin expression correlates with increased expression of CD44...
Article
Full-text available
Esophageal cancer, which frequently exhibits coordinated loss of E-cadherin (Ecad) and transforming growth factor beta (TGFbeta) receptor II (TbetaRII), has a high mortality rate. In a three-dimensional organotypic culture model system, esophageal keratinocytes expressing dominant-negative mutant versions of both Ecad and TbetaRII (ECdnT) invade in...
Article
Aged garlic extract (AGE) is a complex mixture. Its constituents include allin, cycloalliin, S-allyl-L-cysteine, S-methyl-L-cysteine, S-ethylcysteine, S-1-proponyl-L-cysteine, S-allylmercapto-L-cysteine, fructosyl-arginine, and beta-chlorogenin. It also contains L-arginine, L-cysteine, and L-methionine. AGE reduces the parameters associated with ca...
Article
Cardiovascular disease is associated with multiple factors including the increased ability of platelets to aggregate. Aged garlic extract (AGE) was shown to inhibit platelet aggregation; however, the underlying mechanisms have yet to be established. Because calcium mobilization plays an important role in platelet aggregation, the effect of AGE was...

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