Gilberto Berti

Gilberto Berti
University of Ferrara | UNIFE · Department of Morphology, Surgery and Experimental Medicine

About

137
Publications
6,057
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1,557
Citations
Citations since 2017
2 Research Items
784 Citations
2017201820192020202120222023020406080100120140
2017201820192020202120222023020406080100120140
2017201820192020202120222023020406080100120140
2017201820192020202120222023020406080100120140

Publications

Publications (137)
Article
Full-text available
The aim of MED HISS methodology was to test the effectiveness of a low-cost approach to study long-term effects of air pollution, applicable in all European countries. This approach is potentially exportable to other environmental issues where a cohort representative of the country population is needed. The cohort is derived from the National Healt...
Article
Background: The LIFE MED HISS project aims at setting up a surveillance system on the long term effects of air pollution on health, using data from National Health Interview Surveys and other currently available sources of information in most European countries. Few studies assessed the long term effect of air pollution on hospital admissions in Eu...
Article
We performed a multisite study to evaluate demographic and clinical conditions as potential modifiers of the particulate matter (PM)–mortality association. We selected 228,619 natural deaths of elderly persons (ages ≥65 years) that occurred in 12 Italian cities during the period 2006–2010. Individual data on causes of death, age, sex, location of d...
Article
Previous studies reported significant variability of air pollutants across Europe with the lowest concentrations generally found in Northern Europe and the highest in Southern European countries. Within the MED-PARTICLES project the spatial and temporal variations of long-term PM and gaseous pollutants data were investigated in traffic and urban ba...
Article
Full-text available
construction of environmental indicators of air pollution suitable for epidemiological surveillance in 25 Italian cities for EpiAir2 project (2006-2010) and presentation of the results from a 10 years of surveillance system (2001-2010) in 10 Italian cities. data on particulate matter (PM10 and its fine fraction PM2.5), nitrogen dioxide (NO2), and o...
Article
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Background: Evidence on the short-term effects of fine and coarse particles on morbidity in Europe is scarce and inconsistent. oBjectives: We aimed to estimate the association between daily concentrations of fine and coarse particles with hospitalizations for cardiovascular and respiratory conditions in eight Southern European cities, within the ME...
Article
Full-text available
OBJECTIVES: this study aims at presenting the results from the Italian EpiaAir2 Project on the short-term effects of air pollution on adult population (35+ years old) in 25 Italian cities. DESIGN: the short-term effects of air pollution on resident people died in their city were analysed adopting the time series approach. The association between in...
Article
Full-text available
OBJECTIVES: to estimate the short-term impact of air pollutants on adult population of 23 Italian cities on the calendar period 2006-2009 as part of the EpiAir2 project. DESIGN, MATERIALS AND METHODS: for each city, the short-term impact of air pollution on mortality was estimated. In particular, it was calculated the number of deaths attributable...
Article
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OBJECTIVE: to evaluate the relationship between air pollution and hospital admissions in 25 Italian cities that took part in the EpiAir (Epidemiological surveillance of air pollution effects among Italian cities) project. DESIGN: study of time series with case-crossover methodology, with adjustment for meteorological and time-dependent variables. T...
Article
Full-text available
OBJECTIVE: construction of environmental indicators of air pollution suitable for epidemiological surveillance in 25 Italian cities for EpiAir2 project (2006-2010) and presentation of the results from a 10 years of surveillance system (2001-2010) in 10 Italian cities. DESIGN: data on particulate matter (PM10 and its fine fraction PM2.5), nitrogen d...
Article
Full-text available
Background: Evidence on the short-term effects of fine and coarse particles on morbidity in Europe is scarce and inconsistent. Objectives: We aimed to estimate the association between daily concentrations of fine and coarse particles with hospitalizations for cardiovascular and respiratory conditions in eight Southern European cities, within the...
Article
Full-text available
Short-term effects of air pollutants on respiratory mortality and morbidity have been consistently reported but usually studied separately.To more completely assess air pollution effects, we studied hospitalisations for respiratory diseases together with out-of hospital respiratory deaths.A "time-stratified" case-crossover study was carried out in...
Article
Although numerous studies have provided evidence of an association between ambient air pollution and acute cardiac morbidity, little is known regarding susceptibility factors. We conducted a time-stratified case-crossover study in 9 Italian cities between 2001 and 2005 to estimate the short-term association between airborne particles with aerodynam...
Article
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The association of air pollutants with natural and respiratory mortality has been consistently reported. However, several aspects of the relationship between particulate matter with a 50% cut-off aerodynamic diameter of 10 μm (PM(10)) and respiratory mortality require further investigation. The aim of the present study was to assess the PM(10)-resp...
Article
Full-text available
Background: Several studies have shown an association between nitrogen dioxide (NO2) and mortality. In Italy, the EpiAir multicentric study, “Air Pollution and Health: Epidemiological Surveillance and Primary Prevention,” investigated short-term health effects of air pollution, including NO2. Objectives: To study the individual susceptibility, we e...
Article
to produce environmental indicators suitable for an epidemiological surveillance in 10 Italian cities part of the EpiAir Project (2001-2005). the environmental parameters that correlate to relevant health effects are the particles with diameters less than or equal to 10 micrometers (PM10), the nitrogen dioxide (NO2) and the ozone (O3). The necessar...
Article
the EpiAir (Air pollution and health: epidemiological surveillance and prevention) Project has been conducted in 10 Italian cities. In this paper we describe the health data used to detect adverse health effects associated with air pollution exposure (mortality and hospital discharge databases) and to identify comorbidities (based on hospital disch...
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the relationship between air pollution and mortality has been well established in national and international scientific literature. This study reports the results of the EpiAir Project relative to the effect of air pollution on mortality in 10 Italian cities during 2001-2005. The association between particulate matter (PM10) and gases (nitrogen dio...
Article
the relationship between air pollution and hospital admissions has been well studied. In this study, the results of the Italian EpiAir Project are reported on the effect of air pollution on hospital admissions in 9 Italian cities during 2001-2005. The association between particulate matter (PM10) and gases (NO2 and O3) and hospital admissions for c...
Article
Full-text available
The EpiAir Project evaluated the short term effects of air pollution on mortality and morbidity in 10 Italian cities (Milano, Mestre-Venezia, Torino, Bologna, Firenze, Pisa, Roma, Taranto, Cagliari e Palermo) during the period 2001-2005. A time-stratified case-crossover design was adopted, with results equivalent to those found using the traditiona...
Article
We evaluated the association between PM(10) concentration and out-of-hospital coronary deaths in eight Italian cities during 1997-2004. 16 989 subjects aged >35 years who died out-of-hospital from coronary causes were studied and hospital admissions in the previous 2 years identified. We studied the effect of the mean of current and previous day PM...
Article
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Background: Epidemiological studies have provided evidence that exposure to vehicular traffic increases the prevalence of respiratory symptoms and may exacerbate pre-existing asthma in children. Self-reported exposure to road traffic has been questioned as a reliable measurement of exposure to air pollutants. The aim of this study was to investiga...
Data
Associations between traffic indicators and selected respiratory symptoms. The table shows the results of the associations (odds ratios) for: 1. different asthma symptoms; 2. light and severe asthma symptoms; 3. symptoms of cough or phlegm of different duration (1–2 months per year and 3 or more months per year).
Data
Associations between traffic indicators in the overall sample (n = 33,632), by source of information. SIDRIA 2. Table A: for both age groups (6–7 years and 13–14 years), information on exposure and symptoms are those reported by parents. Table B: for the younger age group (6–7 years), information on exposure and symptoms are those reported by paren...
Data
Wording of the traffic questions. The table reports the exact wording of the questions on exposure to traffic.
Data
Traffic exposure in the whole SIDRIA 2 sample. Frequency (numbers and percentages) of reported exposure by each traffic indicator.
Data
Characteristics of subjects (cities of Turin, Milan and Rome) included in the internal validation analysis. Description of the whole sample (N = 9,034) and of the subgroup of subjects that could be matched by census block (N = 2,446) for "cough or phlegm".
Data
Associations between exposure to car transit and respiratory symptoms, by several characteristics. The figure reports the associations (OR and 95% CI) between exposure to car transit (continuous vs never/sometimes) and asthma symptoms and cough or phlegm by different factors (age, gender, latitude, level of urbanization, parental education, indoor...
Data
Characteristics of subjects geocoded in the city of Turin. Distribution of frequencies in subgroups linked and not linked with traffic measurements.
Data
Characteristics of subjects (cities of Turin, Milan and Rome) included in the internal validation analysis. Reported exposure to traffic in the whole sample (first column). For the symptom of "cough or phlegm", exposure to traffic in the subgroups of subjects that could be matched by census block (in which at least one symptomatic and one asymptoma...
Article
Full-text available
In this work we report the results of some quality control tests performed on laboratory procedures referring to aerobiological monitoring activities between 2005 and 2007. In every test, the results of each operator have been compared with the scores of a group of experts. For quality evaluation, we have used accuracy and precision to define the p...
Article
Background: Several time-series studies have established the relationship between particulate matter (PM10) and mortality. We adopted a case-crossover design to evaluate whether individual socio-demographic characteristics and chronic or acute medical conditions modify the PM10-mortality association. Methods: We selected all natural deaths (321,024...
Article
The SIDRIA project (Italian Studies on Respiratory Disorders in Children and the Environment) is a large multicentre, population-based survey within the ISAAC study (International Study on Asthma and Allergies in Childhood), aimed at estimating the prevalence of respiratory and allergic disorders in Italian children and adolescents, and at investig...
Article
The effects of prolonged macrophage depletion on haematological parameters were investigated in aged rats and compared with those in young ones. Four weekly i.v. injections of dichloromethylene diphosphonate-containing liposomes (Cl2MDP-CL) were employed to achieve a prolonged depletion of bone marrow (BM) and spleen macrophages. The number of BM m...
Article
Full-text available
To investigate whether macrophage-depleted rats may serve as a model for studying red blood cell (RBC) aging. Rats were macrophage-depleted by 4 weekly injections of dichloromethylene diphosphonate-containing liposomes (Cl2MDP-CL). The macrophage content of spleens and bone marrows (BMs) was investigated by immunohistochemistry and light microscopy...
Article
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To report on the relation between home mould and/or dampness exposure and respiratory disorders in a large sample of children and adolescents in Italy, accounting for age at time of exposure. 20,016 children (mean age 7 years) and 13,266 adolescents (mean age 13 years) completed questionnaires on indoor exposures and respiratory symptoms/diseases....
Article
The second phase of the SIDRIA study provides important information regarding the family characteristics of Italian children (6-7 years old) and adolescents (13-14 years old), and the frequency of risk factors for asthma and allergies, allowing comparisons between study areas according to differences in latitude (North, Centre, South) and urbanizat...
Article
Full-text available
Prevalence of asthma and allergies in children shows large variations among different populations, but there is limited evidence about these conditions in immigrants from developing countries. The aim of this study was to evaluate the prevalence of asthma symptoms and allergies in immigrant children and adolescents living in Italy and to investigat...
Article
Several studies have shown that indoor pollution increases the risk for chronic pulmonary diseases and acute respiratory symptoms in children/adolescents. Some associations have been confirmed by studies. Other relations are still unclear, such as those regarding dog and cat ownership. In this study we assessed the relationships of the exposure to...
Article
Full-text available
Several epidemiological studies have provided evidence that exposure to auto vehicular traffic increases the prevalence of bronchitis, cough and deficits in lung function and may exacerbate pre-existing asthma, especially in children. The aim of this study was to investigate the role of road traffic pollution on respiratory health in a large sample...
Article
In order to explore the effect on bone marrow macrophages of liposome-encapsulated dichloromethylene diphosphonate (Cl2MDP), mice were injected intravenously with a preparation of such liposomes at a dose known to deplete spleen and liver macrophages. Two days later, the macrophages in the marrow of the femoral bones were quantified by flow cytomet...
Article
In this study, the binding of naturally occurring antibodies as well as of induced anti-spectrin antibodies to red blood cells (RBC), in relation with different ageing conditions, was investigated in the rat. RBC from aged animals, or from rats whose RBC were age-induced either by means of hypertransfusion (which blocks erythropoiesis) or by treatm...
Article
In order to have a model for studying the possible implications of 2-ethylhexyl-phthalate and dialysate on connective tissue, we evaluated their direct effects on the air pouch lining tissue and on fibroblast cultures. Air pouches were formed on the backs of 60 ten-week-old Wistar rats by subcutaneous injections of 10 ml sterile air. On the tenth d...
Article
In the present study we examined five subjects affected by hereditary spherocytosis (three unsplenectomized and two splenectomized), coming from an area in the north-east of Italy where hereditary spherocytosis is an anaemic disease with very low incidence. All patients showed a low degree of spectrin deficiency (14%), detected with sodium dodecyl...
Article
In order to analyse a possible role of anti-spectrin antibodies in the clearance of aged red blood cells (RBC), a homologous system was employed, whereby a population of aged RBC, obtained by hypertransfusion, was injected into rats bearing a high level of anti-spectrin antibodies, following immunization with spectrin. The aged RBC bound the anti-s...
Article
We have previously shown that a subpopulation of cord/fetal red blood cells (RBC) binds rabbit IgG antibodies raised against cord RBC and absorbed on adult RBC (F-IgG), while control IgG, raised against and absorbed on adult RBC (A-IgG), fails to do so. In the present study, F-IgG maintained its binding to cord RBC surface antigens following absorp...
Article
The direct effects of D(2-ethylhexyl)phthalate (DEHP), on subcutaneous tissue were studied in the rat, using the air pouch technique. Two ml of DEHP either undiluted or diluted in olive oil (10 microm/ml), were introduced into a previously created air pouch in the rats. The air pouch was removed and specimens of the lining tissue examined by optica...
Article
Placenta and amnion were analyzed to ascertain the presence of antigens in common with red blood cells (RBC) from cord or fetuses. The expression of distinct antigens displayed on a subpopulation of cord RBC and detected by anticord RBC membrane antibodies was particularly investigated, concomitantly with the presence of transferrin receptors (TR)...
Article
Using the IgG fraction of an antiserum against cord red blood cell (RBC) membranes (F-IgG), antigenic properties of RBC of newborns (n = 24) and patients suffering from anemia (n = 46) [either due to beta-thalassemia intermedia (n = 37) or hemorrhage (n = 9)] as compared to those of normal adults (n = 18) were examined with fluorescence microscopy,...
Article
Minced polyester threads introduced into peritoneal cavity of guinea pigs or rats cause a granulomatous inflammation with evidence of macrophage stimulation. Chemotactic agents play an important role in the inflammatory reaction; they may be exogenous and/or endogenous. These are released locally by the cells involved in inflammation. In this paper...
Article
Minced non adsorbable or adsorbable suture threads introduced into peritoneal cavity of guinea pigs elicit at inflammation with mononuclear and giant cells surrounding suture thread fragments. We studied the presence in the peritoneal cavity of chemotactic factors for PMN cells and we compared the results in relation to the different type of the su...
Article
Purified, homologous spectrin, inner component of red blood cell (RBC) membrane, injected intraperitoneally in rats determines the appearance in the serum of precipitating autoantibodies against spectrin. These have been purified and characterized according to their classes and anti spectrin activity. Immunochemical and immunocytochemical tests, in...
Article
It was previously shown that Yoshida's ascites-hepatoma cells (Y cells) intraperitoneally injected into rats carrying chronic inflammation caused by polyester thread rapidly disappear. In this paper the sedimentation rate in a continuous Percoll gradient at unit gravity (1 g) using the CELSEP apparatus (Sorvall), the mean diameter and volume of the...
Article
It has been known for some years that rats developing a granulomatous inflammation following the intraperitoneal injection of fragments of a polyester suture thread (Mersilene, M) reject a graft of 10(8) Yoshida's ascites hepatoma cells, which on the contrary rapidly grow in M-uninjected animals, originating an ascites tumor and killing the rats in...