Gil Poiares-OliveiraInesc-ID · Information and Decision Support Systems
Gil Poiares-Oliveira
Master of Science
Molecular Systems Biologist
About
5
Publications
347
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14
Citations
Introduction
Molecular Biologist interested in Systems Biology.
Additional affiliations
January 2021 - June 2022
August 2020 - December 2020
Education
September 2019 - June 2022
September 2016 - June 2019
Publications
Publications (5)
In this paper, Long Short-Term Memory (LSTM) networks and multilayered feedforward neural networks (FFNNs) were combined with first principles equations in a hybrid workflow to describe human embryonic kidney 293 (HEK293) culture dynamics. Experimental data of 27 extracellular state variables in 20 fed-batch HEK293 cultures were collected in a para...
MATLAB code of HybridFBA implementation with a toy example
Flux balance analysis (FBA) is currently the standard method to compute metabolic fluxes in genome-scale networks. Several FBA extensions employing diverse objective functions and/or constraints have been published. Here we propose a hybrid semi-parametric FBA extension that combines mechanistic-level constraints (parametric) with empirical constra...
Flux balance analysis is currently the standard method to compute metabolic fluxes in genome-scale networks. Several variations employing diverse objective functions and/or constraints have been published. Here we propose a hybrid semi-parametric version of flux balance analysis that combines mechanistic-level constraints (parametric) with empirica...
