Giampaolo Pitruzzello

Giampaolo Pitruzzello
Springer Nature

PhD

About

18
Publications
5,490
Reads
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206
Citations
Introduction
Associate Editor at Nature Photonics. Eager science communicator eager to convey the latest research to the photonics community.
Additional affiliations
August 2020 - present
The University of York
Position
  • PostDoc Position
Description
  • Optical and electrical characterisation of the antimicrobial susceptibility of individual bacteria by integrating photonics, electrical impedance and microfluidics.

Publications

Publications (18)
Article
Full-text available
Single‐Cell Bacterial Motility Rapidly Identifies Heteroresistance A key issue in the study of antimicrobial resistance is that heterogeneous bacterial populations can display varied responses to antibiotics. In article number 2100123, Giampaolo Pitruzzello, Thomas F. Krauss, and co‐workers show that single‐cell motility measured in microfluidic ar...
Article
Full-text available
Heterogeneous bacterial populations can display increased resistance to external threats, such as exposure to antibiotics. Despite the mounting clinical evidence supporting the importance of bacterial heterogeneity in acute infections, current antimicrobial susceptibility tests (ASTs) are typically insensitive to cell‐to‐cell differences as they on...
Article
Full-text available
Optical trapping has revolutionized our understanding of biology by manipulating cells and single molecules using optical forces. Moving to the near-field creates intense field gradients to trap very smaller particles, such as DNA fragments, viruses, and vesicles. The next frontier for such optical nanotweezers in biomedical applications is to trap...
Article
Full-text available
Dielectric metasurfaces support resonances that are widely explored both for far-field wavefront shaping and for near-field sensing and imaging. Their design explores the interplay between localised and extended resonances, with a typical trade-off between Q-factor and light localisation; high Q-factors are desirable for refractive index sensing wh...
Article
Full-text available
Photonic biosensors are a major topic of research that continues to make exciting advances. Technology has now improved sufficiently for photonics to enter the realm of microbiology and to allow for the detection of individual bacteria. Here, we discuss the different nanophotonic modalities used in this context and highlight the opportunities they...
Preprint
Full-text available
Dielectric metasurfaces support resonances that are widely explored both for far-field wavefront shaping and for near-field sensing and imaging. Their design explores the interplay between localised Mie resonances and extended Bragg resonances, with a typical trade-off between Q-factor and light localisation; high Q-factors are desirable for refrac...
Article
Full-text available
There is an urgent need to develop novel methods for assessing the response of bacteria to antibiotics in a timely manner. Antibiotics are traditionally assessed via their effect on bacteria in a culture medium, which takes 24-48 h and exploits only a single parameter, i.e. growth. Here, we present a multiparameter approach at the single-cell level...
Article
Full-text available
Grating couplers are a fundamental building block of integrated optics as they allow light to be coupled from free-space to on-chip components and vice versa. A challenging task in designing any grating coupler is represented by the need for reducing back reflections at the waveguide-grating interface, which introduce additional losses and undesira...
Article
Full-text available
In guided-wave optics, using gratings to couple between single mode waveguides and single mode fibers and vice versa is well-established. In contrast, the coupling between multimode waveguides is more complex and a much less understood topic, even though multimode coupling is essential for the excitation of guided modes from spatially incoherent so...
Article
Full-text available
This review provides an insight into the recent developments of photonic crystal (PhC)-based devices for sensing and imaging, with a particular emphasis on biosensors. We focus on two main classes of devices, namely sensors based on PhC cavities and those on guided mode resonances (GMRs). This distinction is able to capture the richness of possibil...
Conference Paper
We introduce a 2D waveguide platform employing an integrating cell approach which enables ultra-long optical propagation paths in a very small geometrical footprint. Effective propagation length of 25 cm is demonstrated.
Article
Full-text available
Optical waveguides are the most fundamental building blocks of integrated optical circuits. They are extremely well understood, yet there is still room for surprises. Here, we introduce a novel 2D waveguide platform which affords a strong interaction of the evanescent tail of a guided optical wave with an external medium while only employing a very...
Article
Full-text available
Your teachers and your colleagues have an essential role in helping you to determine your scientific interests and your way of doing research, says Giampaolo Pitruzzello.
Article
Full-text available
A simple and low‐cost approach for the large‐scale production of Au nanodendritic structures on Si is presented. Starting from the methodology involving deposition of a Au film on Si and heating the system to high temperatures in an inert ambient containing trace amounts of oxygen for the growth of SiO2 nanowires (NWs), we show that a suppression o...

Questions

Questions (2)
Question
I am doing a 2D simulation of gold electrodes on a glass substrate immersed in liquid - typically biological solutions, such as PBS with ionic strength of around 100mM. In particular, I am simulating the complex electrical impedance as a function of frequency (basically electrical impedance spectroscopy - EIS). Is there a way to stimulate the presence of the EDL in order to include its screening effects in the EIS spectra? I am currently using the AC/DC module, do I need to use a different one? Which parameters should I know to simulate the formation of the EDL?
Question
Hi everyone,
I am trying to make SU8 conductive by dispersing gold nanoparticles in it. The resist will then be patterned by UV/e-beam lithography. I was wondering about the best way of getting the nanoparticles dispersed in the SU8. I am aiming for a few wt%. Would it be better to use powdered gold or nanoparticles in solution? In the latter case, what is the best buffer to ensure good dispersion? The SU8 I am using is not very viscous, as I do not need very thick films, so my first guess was to use powdered gold + mechanical stirring and ultrasonic.
Any suggestion would be highly appreciated.

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